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The map label for this gene is alr

Identifier: 15594505

GI number: 15594505

Start: 160090

End: 161208

Strand: Direct

Name: alr

Synonym: BB0160

Alternate gene names: 15594505

Gene position: 160090-161208 (Clockwise)

Preceding gene: 15594504

Following gene: 15594507

Centisome position: 17.58

GC content: 23.95

Gene sequence:

>1119_bases
ATGTATAATAATAAAACAATGGGTAGTAACAAAACAATAATAATAAATTTAAATAATTTAGAACATAACTTAAATTTAAT
TAAAAATAAAATTGGCGAAAAAGAAATAGTGGCCACCTTAAAAGGTGACGCATATGGTCACGGACTTATAAACATCTTTA
AATTTTTAAAATCAAAAAACATAAATTATTTTGGACTTTCTAATATTGAAGATGCTAAAACACTTAAAAAAATTGATAAA
AATATAAAAATATTAATGTACATTAAGGTGGATAAAAAAGAAATTAAAAATTTGATTAAATTTGAGTTAGTACCATTTGT
TTCTGATTTTGAATATCTATTTTTAATAGAAAAAGAATGCGCATTGCAAAAAAATAAAATAAAAGTCCACTTAAAAATTG
ATATCGGAATGAATAGATATGGAATAAAAATAGATGATGCCCTTGAAATAGCTACATATATTCAAAATTCAAAATTTCTA
GAACTAGAAGGGATCTGCTCACATCTCCCATCAATAGAAAACTTTAAAACCACACAAAAGCAAATAGAGCAATTCTTATT
TTTTTTAGAAACACTAAAACAAAAAAATATTCATCCCAAATTTGTCCATATTTCTAATTCAGGGCACATTATTAACTACA
AACTAAATCCACAATTTAATATGGTAAGACCAGGTCTTATTCTTTACGGTTACTGTCAATCGCTAAAAAACAAAAAACCT
GCTTTAAATTTTAAGCCTGTATTAAGTTTATTTTCAAAAGTAATATTTATCAAAAATGTCAAAAAGGGTGAAAAAATTTC
ATATTCGGGTATATTTCAAGCCAAAGAAGATATGAAAATAGGAATTATTCCAATCGGATATTTTGATGGAATACCTCAAA
ATATAAGTAATGATTTTTATTTTTTAATAAACAATAAAAAATGTAAAATAAGAGGAAAAGTTTGCATGAATCTGACAATA
GTAGAAATTCCCAAAGACCTAAAAGTTAAAACAGGTTCAAAAGTAGAAATTGTATCAGAAAAATTAAGTATAGATGAAAT
GAGTAAATTTTCTAAAAGAAGTCATTATGAATTACTATGTAATATAGGAAAATACGAAAAGAGAAAATACTTAGATTAA

Upstream 100 bases:

>100_bases
TACATTTTAAAAGCAACCAAATAAAAAAATTTCCAATACCCATTATAGAATAAACTACAAATTAATAGAAAAAAGATTTT
TACTTCTCTAAGAGAGCTAA

Downstream 100 bases:

>100_bases
ATTACCCAAAGAATCAAATTTTTGAAAATCTATTAAATTGCCTCTAGAATCATAAATCCACTTATAAATTGAAAATCCTC
CAACATCATCTCTTAATCTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MYNNKTMGSNKTIIINLNNLEHNLNLIKNKIGEKEIVATLKGDAYGHGLINIFKFLKSKNINYFGLSNIEDAKTLKKIDK
NIKILMYIKVDKKEIKNLIKFELVPFVSDFEYLFLIEKECALQKNKIKVHLKIDIGMNRYGIKIDDALEIATYIQNSKFL
ELEGICSHLPSIENFKTTQKQIEQFLFFLETLKQKNIHPKFVHISNSGHIINYKLNPQFNMVRPGLILYGYCQSLKNKKP
ALNFKPVLSLFSKVIFIKNVKKGEKISYSGIFQAKEDMKIGIIPIGYFDGIPQNISNDFYFLINNKKCKIRGKVCMNLTI
VEIPKDLKVKTGSKVEIVSEKLSIDEMSKFSKRSHYELLCNIGKYEKRKYLD

Sequences:

>Translated_372_residues
MYNNKTMGSNKTIIINLNNLEHNLNLIKNKIGEKEIVATLKGDAYGHGLINIFKFLKSKNINYFGLSNIEDAKTLKKIDK
NIKILMYIKVDKKEIKNLIKFELVPFVSDFEYLFLIEKECALQKNKIKVHLKIDIGMNRYGIKIDDALEIATYIQNSKFL
ELEGICSHLPSIENFKTTQKQIEQFLFFLETLKQKNIHPKFVHISNSGHIINYKLNPQFNMVRPGLILYGYCQSLKNKKP
ALNFKPVLSLFSKVIFIKNVKKGEKISYSGIFQAKEDMKIGIIPIGYFDGIPQNISNDFYFLINNKKCKIRGKVCMNLTI
VEIPKDLKVKTGSKVEIVSEKLSIDEMSKFSKRSHYELLCNIGKYEKRKYLD
>Mature_372_residues
MYNNKTMGSNKTIIINLNNLEHNLNLIKNKIGEKEIVATLKGDAYGHGLINIFKFLKSKNINYFGLSNIEDAKTLKKIDK
NIKILMYIKVDKKEIKNLIKFELVPFVSDFEYLFLIEKECALQKNKIKVHLKIDIGMNRYGIKIDDALEIATYIQNSKFL
ELEGICSHLPSIENFKTTQKQIEQFLFFLETLKQKNIHPKFVHISNSGHIINYKLNPQFNMVRPGLILYGYCQSLKNKKP
ALNFKPVLSLFSKVIFIKNVKKGEKISYSGIFQAKEDMKIGIIPIGYFDGIPQNISNDFYFLINNKKCKIRGKVCMNLTI
VEIPKDLKVKTGSKVEIVSEKLSIDEMSKFSKRSHYELLCNIGKYEKRKYLD

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=370, Percent_Identity=29.1891891891892, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787439, Length=356, Percent_Identity=26.123595505618, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_BORBU (O51182)

Other databases:

- EMBL:   AE000783
- PIR:   H70119
- RefSeq:   NP_212294.1
- ProteinModelPortal:   O51182
- EnsemblBacteria:   EBBORT00000008471
- GeneID:   1194995
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0160
- NMPDR:   fig|224326.1.peg.544
- TIGR:   BB_0160
- GeneTree:   EBGT00050000007269
- HOGENOM:   HBG712172
- OMA:   KKIKVHL
- ProtClustDB:   CLSK507396
- BioCyc:   BBUR224326:BB_0160-MONOMER
- BRENDA:   5.1.1.1
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 43087; Mature: 43087

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 41-41 ACT_SITE 268-268

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNNKTMGSNKTIIINLNNLEHNLNLIKNKIGEKEIVATLKGDAYGHGLINIFKFLKSKN
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCC
INYFGLSNIEDAKTLKKIDKNIKILMYIKVDKKEIKNLIKFELVPFVSDFEYLFLIEKEC
CCEEECCCCHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHEEECCCCCCEEEEEEEHHH
ALQKNKIKVHLKIDIGMNRYGIKIDDALEIATYIQNSKFLELEGICSHLPSIENFKTTQK
CCCCCEEEEEEEEEECCCCCCEEECHHHHHHHHHCCCCEEEEHHHHHHCCCCCHHHHHHH
QIEQFLFFLETLKQKNIHPKFVHISNSGHIINYKLNPQFNMVRPGLILYGYCQSLKNKKP
HHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCEECCCHHHHHHHHHHCCCCC
ALNFKPVLSLFSKVIFIKNVKKGEKISYSGIFQAKEDMKIGIIPIGYFDGIPQNISNDFY
CCCHHHHHHHHHHHHHEECCCCCCEEEECEEEEECCCCEEEEEEECCCCCCCCCCCCCEE
FLINNKKCKIRGKVCMNLTIVEIPKDLKVKTGSKVEIVSEKLSIDEMSKFSKRSHYELLC
EEEECCEEEEEEEEEEEEEEEECCCCCEECCCCEEEEEHHHCCHHHHHHHHCCCCCCEEE
NIGKYEKRKYLD
CCCCCCHHCCCC
>Mature Secondary Structure
MYNNKTMGSNKTIIINLNNLEHNLNLIKNKIGEKEIVATLKGDAYGHGLINIFKFLKSKN
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCC
INYFGLSNIEDAKTLKKIDKNIKILMYIKVDKKEIKNLIKFELVPFVSDFEYLFLIEKEC
CCEEECCCCHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHEEECCCCCCEEEEEEEHHH
ALQKNKIKVHLKIDIGMNRYGIKIDDALEIATYIQNSKFLELEGICSHLPSIENFKTTQK
CCCCCEEEEEEEEEECCCCCCEEECHHHHHHHHHCCCCEEEEHHHHHHCCCCCHHHHHHH
QIEQFLFFLETLKQKNIHPKFVHISNSGHIINYKLNPQFNMVRPGLILYGYCQSLKNKKP
HHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCEECCCHHHHHHHHHHCCCCC
ALNFKPVLSLFSKVIFIKNVKKGEKISYSGIFQAKEDMKIGIIPIGYFDGIPQNISNDFY
CCCHHHHHHHHHHHHHEECCCCCCEEEECEEEEECCCCEEEEEEECCCCCCCCCCCCCEE
FLINNKKCKIRGKVCMNLTIVEIPKDLKVKTGSKVEIVSEKLSIDEMSKFSKRSHYELLC
EEEECCEEEEEEEEEEEEEEEECCCCCEECCCCEEEEEHHHCCHHHHHHHHCCCCCCEEE
NIGKYEKRKYLD
CCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685