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The map label for this gene is nagB [H]

Identifier: 15594497

GI number: 15594497

Start: 152206

End: 153012

Strand: Direct

Name: nagB [H]

Synonym: BB0152

Alternate gene names: 15594497

Gene position: 152206-153012 (Clockwise)

Preceding gene: 15594496

Following gene: 15594500

Centisome position: 16.71

GC content: 31.1

Gene sequence:

>807_bases
ATGAGATTAATAATCAGACCCACATACGAAGACATATCAAAATGGGCGGCTAATCATGTAGCACAAAAAATTAATGAATT
TTCCCCAACAAAAGAAAATCCATTTATCCTTGGACTTCCAACAGGAAGCTCTCCGATTGGCATGTACAAAAACTTAATTG
AATTAAATAAAAATAAAAAAATTTCATTTCAAAATGTCATAACTTTTAATATGGATGAATACATAGGAATTGAAGAAAAT
CATCCTGAAAGTTACCATTCATTTATGTGGAACAATTTTTTTTCCCACATTGACATTAAAAAAGAAAACATAAATATACT
AAACGGAAATGCTTCAAATCTCAAAAAAGAATGCGAAGAATATGAAAAAAAAATCAAATCTTTCGGGGGAATAATGCTTT
TTGTAGGGGGAATAGGCCCCGATGGTCACATTGCTTTTAATGAGCCGGGCTCCTCCTTAACATCAAGAACAAGAATTAAA
ACTTTAACCCAGGATACAATTATTGCTAATTCAAGATTTTTTGAAGGCGATGTAAACAAAGTTCCCAAAAATGCACTAAC
TGTTGGAATTGGAACGATCATGGATTCACAAGAAGTTTTAATAATAGTAAATGGACATAACAAAGCAAGAGCATTAAAGC
ATGCCATTGAAAAAGGCGTTAACCACATGTGGACAATTAGTGCACTCCAACTACATAAAAATGCAATCATAGTATCTGAC
AAAAATGCAACTTACGAATTAAAAGTTGGAACAGTAGAATACTTTAATGATATAGAAAGAAAAAACTTTAATAATGACTT
AAAATAA

Upstream 100 bases:

>100_bases
TCAATGTCCTAGATAAAGATTTTAATCTAAAGTTAACAATGATAGAATCTAAAATAATTTTTAACAATCTCTAACTTTAA
TCAATTTTAAGGAGATCTCA

Downstream 100 bases:

>100_bases
ATTGCTTAAAATTTTAAAGTAAAATACTAAATATAGAATTGAAAATCTTTATAAAGTAAAGGCTAATTAATCACTTCATT
GTAAACTTTTGAAACTTCTT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MRLIIRPTYEDISKWAANHVAQKINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKKISFQNVITFNMDEYIGIEEN
HPESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEEYEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIK
TLTQDTIIANSRFFEGDVNKVPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIVSD
KNATYELKVGTVEYFNDIERKNFNNDLK

Sequences:

>Translated_268_residues
MRLIIRPTYEDISKWAANHVAQKINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKKISFQNVITFNMDEYIGIEEN
HPESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEEYEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIK
TLTQDTIIANSRFFEGDVNKVPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIVSD
KNATYELKVGTVEYFNDIERKNFNNDLK
>Mature_268_residues
MRLIIRPTYEDISKWAANHVAQKINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKKISFQNVITFNMDEYIGIEEN
HPESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEEYEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIK
TLTQDTIIANSRFFEGDVNKVPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIVSD
KNATYELKVGTVEYFNDIERKNFNNDLK

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=258, Percent_Identity=61.6279069767442, Blast_Score=347, Evalue=7e-96,
Organism=Homo sapiens, GI19923881, Length=258, Percent_Identity=60.4651162790698, Blast_Score=344, Evalue=4e-95,
Organism=Escherichia coli, GI1786893, Length=262, Percent_Identity=60.6870229007634, Blast_Score=354, Evalue=4e-99,
Organism=Escherichia coli, GI48994958, Length=242, Percent_Identity=31.8181818181818, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789530, Length=230, Percent_Identity=25.2173913043478, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17554876, Length=258, Percent_Identity=59.3023255813954, Blast_Score=323, Evalue=5e-89,
Organism=Drosophila melanogaster, GI24581960, Length=260, Percent_Identity=60.7692307692308, Blast_Score=357, Evalue=6e-99,
Organism=Drosophila melanogaster, GI19920764, Length=260, Percent_Identity=60.7692307692308, Blast_Score=357, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 30358; Mature: 30358

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIIRPTYEDISKWAANHVAQKINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKK
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCC
ISFQNVITFNMDEYIGIEENHPESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEE
EEEEEEEEECCHHEECCCCCCCHHHHHHHHHHHHHHEEEEECCEEEECCCHHHHHHHHHH
YEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIKTLTQDTIIANSRFFEGDVNK
HHHHHHHCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHCEEEECCEEECCCCCC
VPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIVSD
CCCCCEEEEEHEEECCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEHEEEEECCEEEEEC
KNATYELKVGTVEYFNDIERKNFNNDLK
CCCEEEEEECHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLIIRPTYEDISKWAANHVAQKINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKK
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCC
ISFQNVITFNMDEYIGIEENHPESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEE
EEEEEEEEECCHHEECCCCCCCHHHHHHHHHHHHHHEEEEECCEEEECCCHHHHHHHHHH
YEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIKTLTQDTIIANSRFFEGDVNK
HHHHHHHCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHCEEEECCEEECCCCCC
VPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIVSD
CCCCCEEEEEHEEECCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEHEEEEECCEEEEEC
KNATYELKVGTVEYFNDIERKNFNNDLK
CCCEEEEEECHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA