Click here to switch to the map view.

The map label for this gene is spoVD [H]

Identifier: 15594481

GI number: 15594481

Start: 133975

End: 135864

Strand: Direct

Name: spoVD [H]

Synonym: BB0136

Alternate gene names: 15594481

Gene position: 133975-135864 (Clockwise)

Preceding gene: 15594479

Following gene: 15594488

Centisome position: 14.71

GC content: 28.73

Gene sequence:

>1890_bases
ATGACCAAAAGAATGCTTAATAACACTTATCGAATAAAAACAATATTAACAATATTCTTGGCTATAACTTTGTTAACTAT
TTACAAATATTTCACACTAATGGCCTTCAATAACAGCCCAGACAACACAATATCTTTAAAGTCAAATGATATTGCCAAAA
GAGGAACAATTTATGATAGAAATGGCAAACCAATAGCATTCTCTTCAAAATCCTACTCAATTGGTACAAATCCTCAAAAA
ATAGAAAATATTGTAAGCACATCTGAAACTCTTGGTGCAATACTTCAAATTAATTCAAGAATTTTAAAGGAAAAGCTTTC
CTCTAACAAAGGGTTTTTATATATAAAAAGAAAAATAAAAAGAGAAGAATCAGATTTAATAAAAAGAATTCAAGCTGAAG
GCAGGCTTTCAAACATCACTTTATATCCTGATTACACAAGAATTTATCCCTTCAGGAATACCACAAGCAATATTACTGGT
TTTGTAGGAACAGATAATCTTGGCCTTGAGGGCATTGAATTTTCCCTAAATAGCATATTAGGAAAAGATAAAACCAAGCA
ACAATTTTTAAATGAGGAGCCAGAAACAAACAACATCCACTTAACAATAGACATGGATATACAACAAGGTGTTAGCAAAA
TAGCTAAAAAATACTTTAAAGAAAATAATCCTGAAAGTTTAATTACCTTGGTAATGAACTCCCAAAATGGAGAAATATTA
TCCATGGTTCAATTTCCTCAATATGATGCAAACTTTTATTCTAAATATCCTGAAGAAATCCGAAAAAACCTTTCTTCATC
TCTAACCTATGAGCCCGGAAGCATTAATAAAATTTTTACAGTTGCAATAATATTAGAAAGTGGAAAATTAAATTTAGAAG
AAAAATTTTTAGACAATGGAATATATCAAAAACAATTTCCATCAGGAGAAAAAATTACAATCAAAACATTAAATCCCCCC
TATAAACATATCGACTCTACAGAGATTTTAATTTATTCATCAAATGTTGGAATAGCTTACATTACTGAAAAAGTTAGCAA
TGAATACTTTTATAAAAAACTTTTAGATTTTGGCTTTGGGGAAAAAGTTGGAGTTCCATTTCCCGGAGAAACAAAAGGAC
TGCTAAATCATTATTCAAAATGGTCAGGACGAAGTAAAGCTACAATTGGATTTGGACAAGAAATAGGAGTGTCAGCGGTT
CAAATATTACAAGCTGCAAGCATACTAAGCAATAATGGAATAATGCTAAAACCTAGAATAATAAAAAAAATAAGCAACGA
TAAAGGAGAAAATATTAAAGAATTTGATAAAGAAGAAATAAGAAAAGTAATATCCAAAAATTCAGCACAAAAAGTTTTAA
AAATGATGAGAGAAGTTGTAAATAAAGGTGGAATTCCAAATCTTAAAATTAAAAATCTTGACATTTCTGCAAAAAGTGGA
ACATCTCAAGCTATTGATAGAAAAACGGGAAAATACTCAGAAGAAGACTATACATCTTCTATATTGGCAATATACCCCAC
AGAACAACCAAAATATATTATTTACATTGTATACAGATACCCAAAAAAAATAATATACGGAACAAGAATAGCAGCCCCAA
TGGCAAAAGAAATAATAGAATTTATTGAGCACCAACAAAATACAATAGCATATAAAAAAATTAAAATGCCATCAAAAATC
AAGATCCCTAAAGCTGAAACTAATTACAAAAACAAAACATACTTACCAAATTTTATCAACCTTTCTAAAAGAGAAGCAAT
AGACATACTAAAATACTATAAAAATACTATGAAAATAAAAATAAATGGCGATGGATTTGTTTACAAGCAAAGTATATCCC
CCAATACAAAATTAGAAGATATAACAGAGCTTGAACTGTATTTAAAATAA

Upstream 100 bases:

>100_bases
TTTTTCAGAATATAATAACATATAATAATATAGATGCAAAAAAAAATGAATAATTTTTTATTTCATATAGTCATAAAATA
ATTTAAGAGGTCCAAAATTC

Downstream 100 bases:

>100_bases
TTGGGTTAATTAAATAAATAAATTTTTAATTTCATTTTTATAAAAATTTAAAATATAGCTTCGCTTAATGTCCATTTTAA
TAGACATTTCTTTACCAACT

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MTKRMLNNTYRIKTILTIFLAITLLTIYKYFTLMAFNNSPDNTISLKSNDIAKRGTIYDRNGKPIAFSSKSYSIGTNPQK
IENIVSTSETLGAILQINSRILKEKLSSNKGFLYIKRKIKREESDLIKRIQAEGRLSNITLYPDYTRIYPFRNTTSNITG
FVGTDNLGLEGIEFSLNSILGKDKTKQQFLNEEPETNNIHLTIDMDIQQGVSKIAKKYFKENNPESLITLVMNSQNGEIL
SMVQFPQYDANFYSKYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNGIYQKQFPSGEKITIKTLNPP
YKHIDSTEILIYSSNVGIAYITEKVSNEYFYKKLLDFGFGEKVGVPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAV
QILQAASILSNNGIMLKPRIIKKISNDKGENIKEFDKEEIRKVISKNSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIEFIEHQQNTIAYKKIKMPSKI
KIPKAETNYKNKTYLPNFINLSKREAIDILKYYKNTMKIKINGDGFVYKQSISPNTKLEDITELELYLK

Sequences:

>Translated_629_residues
MTKRMLNNTYRIKTILTIFLAITLLTIYKYFTLMAFNNSPDNTISLKSNDIAKRGTIYDRNGKPIAFSSKSYSIGTNPQK
IENIVSTSETLGAILQINSRILKEKLSSNKGFLYIKRKIKREESDLIKRIQAEGRLSNITLYPDYTRIYPFRNTTSNITG
FVGTDNLGLEGIEFSLNSILGKDKTKQQFLNEEPETNNIHLTIDMDIQQGVSKIAKKYFKENNPESLITLVMNSQNGEIL
SMVQFPQYDANFYSKYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNGIYQKQFPSGEKITIKTLNPP
YKHIDSTEILIYSSNVGIAYITEKVSNEYFYKKLLDFGFGEKVGVPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAV
QILQAASILSNNGIMLKPRIIKKISNDKGENIKEFDKEEIRKVISKNSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIEFIEHQQNTIAYKKIKMPSKI
KIPKAETNYKNKTYLPNFINLSKREAIDILKYYKNTMKIKINGDGFVYKQSISPNTKLEDITELELYLK
>Mature_628_residues
TKRMLNNTYRIKTILTIFLAITLLTIYKYFTLMAFNNSPDNTISLKSNDIAKRGTIYDRNGKPIAFSSKSYSIGTNPQKI
ENIVSTSETLGAILQINSRILKEKLSSNKGFLYIKRKIKREESDLIKRIQAEGRLSNITLYPDYTRIYPFRNTTSNITGF
VGTDNLGLEGIEFSLNSILGKDKTKQQFLNEEPETNNIHLTIDMDIQQGVSKIAKKYFKENNPESLITLVMNSQNGEILS
MVQFPQYDANFYSKYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNGIYQKQFPSGEKITIKTLNPPY
KHIDSTEILIYSSNVGIAYITEKVSNEYFYKKLLDFGFGEKVGVPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAVQ
ILQAASILSNNGIMLKPRIIKKISNDKGENIKEFDKEEIRKVISKNSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSGT
SQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIEFIEHQQNTIAYKKIKMPSKIK
IPKAETNYKNKTYLPNFINLSKREAIDILKYYKNTMKIKINGDGFVYKQSISPNTKLEDITELELYLK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=571, Percent_Identity=25.3940455341506, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1786854, Length=486, Percent_Identity=21.8106995884774, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 71749; Mature: 71618

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRMLNNTYRIKTILTIFLAITLLTIYKYFTLMAFNNSPDNTISLKSNDIAKRGTIYDR
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCHHCCCEEEC
NGKPIAFSSKSYSIGTNPQKIENIVSTSETLGAILQINSRILKEKLSSNKGFLYIKRKIK
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHC
REESDLIKRIQAEGRLSNITLYPDYTRIYPFRNTTSNITGFVGTDNLGLEGIEFSLNSIL
CCHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHH
GKDKTKQQFLNEEPETNNIHLTIDMDIQQGVSKIAKKYFKENNPESLITLVMNSQNGEIL
CCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEE
SMVQFPQYDANFYSKYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNG
EEEECCCCCCHHHHCCHHHHHHHHHHCCEECCCCCCEEEEEEEEEECCCCCHHHHHHCCC
IYQKQFPSGEKITIKTLNPPYKHIDSTEILIYSSNVGIAYITEKVSNEYFYKKLLDFGFG
CCCCCCCCCCEEEEEECCCCHHHCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCC
EKVGVPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAVQILQAASILSNNGIMLKPRI
CCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEECHHH
IKKISNDKGENIKEFDKEEIRKVISKNSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
HHHHCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIE
CHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHEECCHHHHHHHHHHHH
FIEHQQNTIAYKKIKMPSKIKIPKAETNYKNKTYLPNFINLSKREAIDILKYYKNTMKIK
HHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCEEEEE
INGDGFVYKQSISPNTKLEDITELELYLK
ECCCCEEEECCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
TKRMLNNTYRIKTILTIFLAITLLTIYKYFTLMAFNNSPDNTISLKSNDIAKRGTIYDR
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCHHCCCEEEC
NGKPIAFSSKSYSIGTNPQKIENIVSTSETLGAILQINSRILKEKLSSNKGFLYIKRKIK
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHC
REESDLIKRIQAEGRLSNITLYPDYTRIYPFRNTTSNITGFVGTDNLGLEGIEFSLNSIL
CCHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHH
GKDKTKQQFLNEEPETNNIHLTIDMDIQQGVSKIAKKYFKENNPESLITLVMNSQNGEIL
CCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEE
SMVQFPQYDANFYSKYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNG
EEEECCCCCCHHHHCCHHHHHHHHHHCCEECCCCCCEEEEEEEEEECCCCCHHHHHHCCC
IYQKQFPSGEKITIKTLNPPYKHIDSTEILIYSSNVGIAYITEKVSNEYFYKKLLDFGFG
CCCCCCCCCCEEEEEECCCCHHHCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCC
EKVGVPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAVQILQAASILSNNGIMLKPRI
CCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEECHHH
IKKISNDKGENIKEFDKEEIRKVISKNSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
HHHHCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIE
CHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHEECCHHHHHHHHHHHH
FIEHQQNTIAYKKIKMPSKIKIPKAETNYKNKTYLPNFINLSKREAIDILKYYKNTMKIK
HHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCEEEEE
INGDGFVYKQSISPNTKLEDITELELYLK
ECCCCEEEECCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]