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The map label for this gene is rnhB [H]

Identifier: 15594392

GI number: 15594392

Start: 45446

End: 45991

Strand: Direct

Name: rnhB [H]

Synonym: BB0046

Alternate gene names: 15594392

Gene position: 45446-45991 (Clockwise)

Preceding gene: 15594387

Following gene: 15594396

Centisome position: 4.99

GC content: 28.39

Gene sequence:

>546_bases
ATGATTTGCGGAATAGATGAAGTCGGAAGGGGTTGTATTTTTGGACCTATTCTAAGTGCTGCTGTGGTTTTCAAAAAAAA
GCCCAGCTTTATAAAAGAATTGGATGATTCTAAAAAACTAAAAAAAGAAAAAAGAGAGTACCTATCCTCATTAATACTTG
AAAACTCATATTATGCATTTGCTGAAATTTCAAATATAACAATAGAAAAAATAAATATTCACAACGCATCCCTTCTTGCA
ATGCAAACTGCATACGAAAACCTAAAATTAAATTGCAGCTTAGTACTTGTAGATGGCAAATTTGTACCCAAAATAACAGC
AAAAAATGTTAAAGCAATAATTAAAGGAGATTCAATAATAGATGAAATAAAAGCTGCTTCAATTATTGCTAAAGTTAAAA
GAGACAAACTAATGGATAAATATGATAAAATTTACCCATTGTATTTACTCAAAAAAAATAAAGGATACCCCACAAAAGAA
CATAAAAACGCAATAAAGAAATATGGGGTCTTAAGCCTTCATAGAAAAAATTTTAAACTAATTTAA

Upstream 100 bases:

>100_bases
TAAAACCAAACTAACTCCCAATTAAAATTAAAAACCAATTACTGATAAATCTACAATTTCATATTATAATAAATAAAAAT
ATTTTAAAAAAAGGTCAATT

Downstream 100 bases:

>100_bases
AAAATAAAAATAATAAAATTTAATAATCCTTCTTTTTAAATCGCCCGCCTGATAAATGAGATTTCTTATCAAATCTAGAA
TCGTCTAATTTAGATCTCTC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MICGIDEVGRGCIFGPILSAAVVFKKKPSFIKELDDSKKLKKEKREYLSSLILENSYYAFAEISNITIEKINIHNASLLA
MQTAYENLKLNCSLVLVDGKFVPKITAKNVKAIIKGDSIIDEIKAASIIAKVKRDKLMDKYDKIYPLYLLKKNKGYPTKE
HKNAIKKYGVLSLHRKNFKLI

Sequences:

>Translated_181_residues
MICGIDEVGRGCIFGPILSAAVVFKKKPSFIKELDDSKKLKKEKREYLSSLILENSYYAFAEISNITIEKINIHNASLLA
MQTAYENLKLNCSLVLVDGKFVPKITAKNVKAIIKGDSIIDEIKAASIIAKVKRDKLMDKYDKIYPLYLLKKNKGYPTKE
HKNAIKKYGVLSLHRKNFKLI
>Mature_181_residues
MICGIDEVGRGCIFGPILSAAVVFKKKPSFIKELDDSKKLKKEKREYLSSLILENSYYAFAEISNITIEKINIHNASLLA
MQTAYENLKLNCSLVLVDGKFVPKITAKNVKAIIKGDSIIDEIKAASIIAKVKRDKLMDKYDKIYPLYLLKKNKGYPTKE
HKNAIKKYGVLSLHRKNFKLI

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=180, Percent_Identity=38.3333333333333, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 20526; Mature: 20526

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICGIDEVGRGCIFGPILSAAVVFKKKPSFIKELDDSKKLKKEKREYLSSLILENSYYAF
CCCCCHHHCCCEEHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEE
AEISNITIEKINIHNASLLAMQTAYENLKLNCSLVLVDGKFVPKITAKNVKAIIKGDSII
EEECCEEEEEEEECCCHHHHHHHHHHCEEEEEEEEEECCCCCCCCCCCCCEEEECCCHHH
DEIKAASIIAKVKRDKLMDKYDKIYPLYLLKKNKGYPTKEHKNAIKKYGVLSLHRKNFKL
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCC
I
C
>Mature Secondary Structure
MICGIDEVGRGCIFGPILSAAVVFKKKPSFIKELDDSKKLKKEKREYLSSLILENSYYAF
CCCCCHHHCCCEEHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEE
AEISNITIEKINIHNASLLAMQTAYENLKLNCSLVLVDGKFVPKITAKNVKAIIKGDSII
EEECCEEEEEEEECCCHHHHHHHHHHCEEEEEEEEEECCCCCCCCCCCCCEEEECCCHHH
DEIKAASIIAKVKRDKLMDKYDKIYPLYLLKKNKGYPTKEHKNAIKKYGVLSLHRKNFKL
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA