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The map label for this gene is smc [H]

Identifier: 15594391

GI number: 15594391

Start: 42907

End: 45366

Strand: Reverse

Name: smc [H]

Synonym: BB0045

Alternate gene names: 15594391

Gene position: 45366-42907 (Counterclockwise)

Preceding gene: 15594393

Following gene: 15594390

Centisome position: 4.98

GC content: 25.98

Gene sequence:

>2460_bases
TTGGGAGTTAGTTTGGTTTTAAAAAAAATAGTGCTTTTAGGGTTTAAATCTTTTCTAAATAGACAAGAGTTTGAAATAGG
TGAAAATTTAAGTTTTATTGTGGGGCCTAATGGATGTGGGAAGAGCAATCTTATTGATGCTGTACGTTTTTGTATGGGAG
AAGATAATTTAAAATTTTTAAGGGTTGAAGATATTTCTGATTTAATTTCTGTTTCAAAATCAGGAAAATCAAATTTTGCC
GAAATAACTCTTTTTTTTAGCAACATTAACTCTGAAAAATCGACTTTAAAGGAATTTAATGAAGATTTTTATATTCGCAG
GCGTCTTTATAAGGATGGTTCAAGTGAATATTATTTTAATAATAAAATTTTGAATTTTCAAGATTATAATAGACTTTTGA
ACAGTTTTAAGTTTAAAAAATCGCCTTATATGTTTATAACTCAAGGTAGGGTTGAGGACATTTCTTTGGAAAGAAATGTA
AATCTCAAATCTTTGATTGAACAAGCAAGCGGAATAGATATTTTAAAAATGGAAGAAGAAGAGGCCTTGAAAAATTTTAA
GCAATCTAGTCAAAATTTATCATCTTTGTTGTCTCTGCAAGAAAATTTAAGGCAAAAGTACGATAACATAAAAAATGTTT
TCCTTTTGAGAAAAAAACATCAAGATTTAAGTCAAAAATTAGAAGCTTTAGAAAAAACAATAACGTTAAAAAAGCTTTTC
AATATTAATTTTGATCTTAATGTCTTGAAGAGCGAATTAAATTTAGACGGTTTGAGTAAATTTTTGTCTTCTGGTTTTAA
AGAAAAGTTAGAATTTTATTCATTTAGAGAAAAAAATGTTATTAATAATATTCAAGAATTAGAAAAAGATCTTGAGCTTA
TGAAGTCTAAAATTCTTGGGCTAGAGATTAAAATTCAAAAATTAGAGCAAGAAAAGACGTTAAAGATGAATTTGGAAGAT
AAGTTTGTCAAGAGCAAATCTGAGTCTGAAGAGAAAAAGAATTCTATAAATAATAATTTATATCAATTAAATAGTTTGCT
TAAAGAAAAGAAAAATGATTTTTTTTCTTTAAGTGACGAGATTAATAGGTATACTAAAAGTTTTTTTGAACTTGTTGATC
TAATTTTGTCTGTATTAAGGAGTGCCAAATCAGAAGAGTTTGTTTTATTAAAAGAGCATATATTAGACTCTCTTAAACTT
TTTGAAGAATCATTGAGTATAAAATATATTAAAGAGATTAGGGTAAATTTAATCAAGTATATAAGCAAAGATGAGAATCT
TTTGGCTTTATTGAGGGATAAAATTGAACCTATTTTTGATCAAAATGTTAATTTGAAAAAATTTTTGCTTGAAAAAAATG
CTTTAAAATCAAATCTTGCTAAAGAGATAACAAATATCGAGAGATTAATCGAAGAAAAGACTCTTCAATTAAATGATGTA
TTGGGTGAGCTTGAGTATATAGAGCTTTCTAAGTTTAAAAATTTGGATGAAATTAAACTTATAGATGGTAATTTAGAATT
TTTATTTGAATCTAAGAATAGCCTTGATGAAGAGCTTAAAGACTTATATTTAAAGCTTGAAAATTTAAATTTAGAAAAAA
GCGATATTCAGCTTAATTTAAGCAATCTTATTGGTGCTTCAAAATTCAGTAGTGAGTCTTTTAAGGAGAAAGATTTTAAT
TCCTTAGTTTTTTTGAATGATTTTAAAAAAACTAATTATTATGAATATATAAAAAAACAGACAGAATACGAATTTCTTTT
AAATTCTAATGTAAGCATTAAGAGCGAAATAGAAAATTTCAATGTTTCTAATGAAATGTCTGATAAATTTGAATTGGAAG
AAGATCTTGCAACCAGAGAGTTGTTGCGCAAAGAGATAGATGCAATCAAGCTGGGTGATTATGTATTTTTCAATATTGAT
AAAGAGTTTGATGAAACTAAGGAGCGTTTTGAAAAAGTAAGTTTACAAGTAGAAGATTTAAAGCTTTCAAAATATTCATT
ACAAAAGCTTCAAAAAAAAATAAAAAATGAGATTTATAAAAAATTTAGAGAATCATTTGATGAGATTAATAAAAATTTTT
CTTTCTTTTTTAAAAAAATTTTTAAAGGAACCGCTAGTCTTTTTTATAATGAAAATACCGATAATGTTGAGATTAGAATA
AATTTTTCAAACAAGTTTGTCAAAAACAATAACATGCTTTCAGGGGGCGAGAGTACTTTGGTTAGTATGGCTTTTTTATT
TGCACTTTATTATTATTCTCCTGCTTGTTTTTGCATGCTTGATGAAATAGATGCAGCTCTTGATTTTGAAAATAGCAAAA
AACTTTCTTTACTTTTAAGAGAATTGGGTAAAAAGTTCCAACTCTTAGTAATAACCCATAATGCATATGTTTCTGAGGGT
GGTGAAAATTTGATAGGTATTACACTTGATAATGGTGAAAGCAGGGTGTTTAATATATAA

Upstream 100 bases:

>100_bases
TTCATCTATTCCGCAAATCATAATTGACCTTTTTTTAAAATATTTTTATTTATTATAATATGAAATTGTAGATTTATCAG
TAATTGGTTTTTAATTTTAA

Downstream 100 bases:

>100_bases
TTAAGTTAGATTTAAGGAAATTAACATGCAAGATAGAAAGTTTAGTTTTAGAAAATATTTTTTAATTTCAGTATTTTTGA
TTTTTATTGTTTCTGGTATT

Product: P115 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 819; Mature: 818

Protein sequence:

>819_residues
MGVSLVLKKIVLLGFKSFLNRQEFEIGENLSFIVGPNGCGKSNLIDAVRFCMGEDNLKFLRVEDISDLISVSKSGKSNFA
EITLFFSNINSEKSTLKEFNEDFYIRRRLYKDGSSEYYFNNKILNFQDYNRLLNSFKFKKSPYMFITQGRVEDISLERNV
NLKSLIEQASGIDILKMEEEEALKNFKQSSQNLSSLLSLQENLRQKYDNIKNVFLLRKKHQDLSQKLEALEKTITLKKLF
NINFDLNVLKSELNLDGLSKFLSSGFKEKLEFYSFREKNVINNIQELEKDLELMKSKILGLEIKIQKLEQEKTLKMNLED
KFVKSKSESEEKKNSINNNLYQLNSLLKEKKNDFFSLSDEINRYTKSFFELVDLILSVLRSAKSEEFVLLKEHILDSLKL
FEESLSIKYIKEIRVNLIKYISKDENLLALLRDKIEPIFDQNVNLKKFLLEKNALKSNLAKEITNIERLIEEKTLQLNDV
LGELEYIELSKFKNLDEIKLIDGNLEFLFESKNSLDEELKDLYLKLENLNLEKSDIQLNLSNLIGASKFSSESFKEKDFN
SLVFLNDFKKTNYYEYIKKQTEYEFLLNSNVSIKSEIENFNVSNEMSDKFELEEDLATRELLRKEIDAIKLGDYVFFNID
KEFDETKERFEKVSLQVEDLKLSKYSLQKLQKKIKNEIYKKFRESFDEINKNFSFFFKKIFKGTASLFYNENTDNVEIRI
NFSNKFVKNNNMLSGGESTLVSMAFLFALYYYSPACFCMLDEIDAALDFENSKKLSLLLRELGKKFQLLVITHNAYVSEG
GENLIGITLDNGESRVFNI

Sequences:

>Translated_819_residues
MGVSLVLKKIVLLGFKSFLNRQEFEIGENLSFIVGPNGCGKSNLIDAVRFCMGEDNLKFLRVEDISDLISVSKSGKSNFA
EITLFFSNINSEKSTLKEFNEDFYIRRRLYKDGSSEYYFNNKILNFQDYNRLLNSFKFKKSPYMFITQGRVEDISLERNV
NLKSLIEQASGIDILKMEEEEALKNFKQSSQNLSSLLSLQENLRQKYDNIKNVFLLRKKHQDLSQKLEALEKTITLKKLF
NINFDLNVLKSELNLDGLSKFLSSGFKEKLEFYSFREKNVINNIQELEKDLELMKSKILGLEIKIQKLEQEKTLKMNLED
KFVKSKSESEEKKNSINNNLYQLNSLLKEKKNDFFSLSDEINRYTKSFFELVDLILSVLRSAKSEEFVLLKEHILDSLKL
FEESLSIKYIKEIRVNLIKYISKDENLLALLRDKIEPIFDQNVNLKKFLLEKNALKSNLAKEITNIERLIEEKTLQLNDV
LGELEYIELSKFKNLDEIKLIDGNLEFLFESKNSLDEELKDLYLKLENLNLEKSDIQLNLSNLIGASKFSSESFKEKDFN
SLVFLNDFKKTNYYEYIKKQTEYEFLLNSNVSIKSEIENFNVSNEMSDKFELEEDLATRELLRKEIDAIKLGDYVFFNID
KEFDETKERFEKVSLQVEDLKLSKYSLQKLQKKIKNEIYKKFRESFDEINKNFSFFFKKIFKGTASLFYNENTDNVEIRI
NFSNKFVKNNNMLSGGESTLVSMAFLFALYYYSPACFCMLDEIDAALDFENSKKLSLLLRELGKKFQLLVITHNAYVSEG
GENLIGITLDNGESRVFNI
>Mature_818_residues
GVSLVLKKIVLLGFKSFLNRQEFEIGENLSFIVGPNGCGKSNLIDAVRFCMGEDNLKFLRVEDISDLISVSKSGKSNFAE
ITLFFSNINSEKSTLKEFNEDFYIRRRLYKDGSSEYYFNNKILNFQDYNRLLNSFKFKKSPYMFITQGRVEDISLERNVN
LKSLIEQASGIDILKMEEEEALKNFKQSSQNLSSLLSLQENLRQKYDNIKNVFLLRKKHQDLSQKLEALEKTITLKKLFN
INFDLNVLKSELNLDGLSKFLSSGFKEKLEFYSFREKNVINNIQELEKDLELMKSKILGLEIKIQKLEQEKTLKMNLEDK
FVKSKSESEEKKNSINNNLYQLNSLLKEKKNDFFSLSDEINRYTKSFFELVDLILSVLRSAKSEEFVLLKEHILDSLKLF
EESLSIKYIKEIRVNLIKYISKDENLLALLRDKIEPIFDQNVNLKKFLLEKNALKSNLAKEITNIERLIEEKTLQLNDVL
GELEYIELSKFKNLDEIKLIDGNLEFLFESKNSLDEELKDLYLKLENLNLEKSDIQLNLSNLIGASKFSSESFKEKDFNS
LVFLNDFKKTNYYEYIKKQTEYEFLLNSNVSIKSEIENFNVSNEMSDKFELEEDLATRELLRKEIDAIKLGDYVFFNIDK
EFDETKERFEKVSLQVEDLKLSKYSLQKLQKKIKNEIYKKFRESFDEINKNFSFFFKKIFKGTASLFYNENTDNVEIRIN
FSNKFVKNNNMLSGGESTLVSMAFLFALYYYSPACFCMLDEIDAALDFENSKKLSLLLRELGKKFQLLVITHNAYVSEGG
ENLIGITLDNGESRVFNI

Specific function: Plays an important role in chromosome structure and partitioning. Essential for chromosome partition [H]

COG id: COG1196

COG function: function code D; Chromosome segregation ATPases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMC family [H]

Homologues:

Organism=Homo sapiens, GI110347425, Length=173, Percent_Identity=30.0578034682081, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110347420, Length=173, Percent_Identity=30.0578034682081, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110347418, Length=173, Percent_Identity=30.0578034682081, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI71565160, Length=147, Percent_Identity=31.9727891156463, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI30581135, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI4885399, Length=173, Percent_Identity=26.0115606936416, Blast_Score=69, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202684, Length=171, Percent_Identity=28.6549707602339, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17553272, Length=153, Percent_Identity=33.9869281045752, Blast_Score=73, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI212656546, Length=188, Percent_Identity=23.936170212766, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193210872, Length=188, Percent_Identity=23.936170212766, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321104, Length=180, Percent_Identity=28.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321144, Length=240, Percent_Identity=24.1666666666667, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322387, Length=181, Percent_Identity=27.6243093922652, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323115, Length=142, Percent_Identity=35.2112676056338, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649535, Length=156, Percent_Identity=32.6923076923077, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19922276, Length=172, Percent_Identity=28.4883720930233, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584683, Length=159, Percent_Identity=30.8176100628931, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642557, Length=151, Percent_Identity=26.4900662251656, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24642555, Length=151, Percent_Identity=26.4900662251656, Blast_Score=67, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003395
- InterPro:   IPR010935
- InterPro:   IPR011890 [H]

Pfam domain/function: PF06470 SMC_hinge; PF02463 SMC_N [H]

EC number: NA

Molecular weight: Translated: 95858; Mature: 95727

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSLVLKKIVLLGFKSFLNRQEFEIGENLSFIVGPNGCGKSNLIDAVRFCMGEDNLKFL
CCHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEE
RVEDISDLISVSKSGKSNFAEITLFFSNINSEKSTLKEFNEDFYIRRRLYKDGSSEYYFN
EEHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHCHHHHHHHHHHCCCCCCEEEC
NKILNFQDYNRLLNSFKFKKSPYMFITQGRVEDISLERNVNLKSLIEQASGIDILKMEEE
CEEECHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHCCCCEEEECHH
EALKNFKQSSQNLSSLLSLQENLRQKYDNIKNVFLLRKKHQDLSQKLEALEKTITLKKLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NINFDLNVLKSELNLDGLSKFLSSGFKEKLEFYSFREKNVINNIQELEKDLELMKSKILG
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEIKIQKLEQEKTLKMNLEDKFVKSKSESEEKKNSINNNLYQLNSLLKEKKNDFFSLSDE
CEEEHHHHCCCHHEEECCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHH
INRYTKSFFELVDLILSVLRSAKSEEFVLLKEHILDSLKLFEESLSIKYIKEIRVNLIKY
HHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISKDENLLALLRDKIEPIFDQNVNLKKFLLEKNALKSNLAKEITNIERLIEEKTLQLNDV
HCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGELEYIELSKFKNLDEIKLIDGNLEFLFESKNSLDEELKDLYLKLENLNLEKSDIQLNL
HCCHHHHHHHHCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHEEEH
SNLIGASKFSSESFKEKDFNSLVFLNDFKKTNYYEYIKKQTEYEFLLNSNVSIKSEIENF
HHHHCCCCCCCCHHCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHEECCCCCHHHHHHCC
NVSNEMSDKFELEEDLATRELLRKEIDAIKLGDYVFFNIDKEFDETKERFEKVSLQVEDL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCEEEEECCCHHHHHHHHHHHHCCCHHHH
KLSKYSLQKLQKKIKNEIYKKFRESFDEINKNFSFFFKKIFKGTASLFYNENTDNVEIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCEEEEEE
NFSNKFVKNNNMLSGGESTLVSMAFLFALYYYSPACFCMLDEIDAALDFENSKKLSLLLR
EECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ELGKKFQLLVITHNAYVSEGGENLIGITLDNGESRVFNI
HHCCCEEEEEEEECCHHCCCCCEEEEEEEECCCCCEECC
>Mature Secondary Structure 
GVSLVLKKIVLLGFKSFLNRQEFEIGENLSFIVGPNGCGKSNLIDAVRFCMGEDNLKFL
CHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEE
RVEDISDLISVSKSGKSNFAEITLFFSNINSEKSTLKEFNEDFYIRRRLYKDGSSEYYFN
EEHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHCHHHHHHHHHHCCCCCCEEEC
NKILNFQDYNRLLNSFKFKKSPYMFITQGRVEDISLERNVNLKSLIEQASGIDILKMEEE
CEEECHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHCCCCEEEECHH
EALKNFKQSSQNLSSLLSLQENLRQKYDNIKNVFLLRKKHQDLSQKLEALEKTITLKKLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NINFDLNVLKSELNLDGLSKFLSSGFKEKLEFYSFREKNVINNIQELEKDLELMKSKILG
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEIKIQKLEQEKTLKMNLEDKFVKSKSESEEKKNSINNNLYQLNSLLKEKKNDFFSLSDE
CEEEHHHHCCCHHEEECCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHH
INRYTKSFFELVDLILSVLRSAKSEEFVLLKEHILDSLKLFEESLSIKYIKEIRVNLIKY
HHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISKDENLLALLRDKIEPIFDQNVNLKKFLLEKNALKSNLAKEITNIERLIEEKTLQLNDV
HCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGELEYIELSKFKNLDEIKLIDGNLEFLFESKNSLDEELKDLYLKLENLNLEKSDIQLNL
HCCHHHHHHHHCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHEEEH
SNLIGASKFSSESFKEKDFNSLVFLNDFKKTNYYEYIKKQTEYEFLLNSNVSIKSEIENF
HHHHCCCCCCCCHHCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHEECCCCCHHHHHHCC
NVSNEMSDKFELEEDLATRELLRKEIDAIKLGDYVFFNIDKEFDETKERFEKVSLQVEDL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCEEEEECCCHHHHHHHHHHHHCCCHHHH
KLSKYSLQKLQKKIKNEIYKKFRESFDEINKNFSFFFKKIFKGTASLFYNENTDNVEIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCEEEEEE
NFSNKFVKNNNMLSGGESTLVSMAFLFALYYYSPACFCMLDEIDAALDFENSKKLSLLLR
EECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ELGKKFQLLVITHNAYVSEGGENLIGITLDNGESRVFNI
HHCCCEEEEEEEECCHHCCCCCEEEEEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]