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The map label for this gene is lytS [H]

Identifier: 154687025

GI number: 154687025

Start: 2719149

End: 2720930

Strand: Reverse

Name: lytS [H]

Synonym: RBAM_025970

Alternate gene names: 154687025

Gene position: 2720930-2719149 (Counterclockwise)

Preceding gene: 154687027

Following gene: 154687024

Centisome position: 69.44

GC content: 50.62

Gene sequence:

>1782_bases
ATGCTGCATTTGATCATCATGATGCTGGAAAGAGTCGGAATTATCGTCATATTGGGATTTGTTCTGGCTCATACCAGATT
GTTCAGACAGGCGCTCCAGCAGCCTGAGAGCTATAAAGGCAAAGCGGTGCTGATTTCAATTTTCTCGCTGTTCAGTATCA
TCAGCAACTATACGGGAATAGAAATTCAGCGGAATACAATCATGAATAATGACTGGGTGTTTCAAATTAATCCGTCCGGT
TCAATTGCCAATACAAGAATTATGGGCGTTGAAATCGGCGGACTCTTAGGCGGCCCGTATGTGGGGATCGGCGTCGGCAT
ACTGGCCGGCCTGCATCGTTTATCACTCGGCGGCGCGACCGCAGTCAGCTGTGCCGTCTCATCCGTTTTAGCGGGCATTT
TGTCCGGATGGATCGGACGGTATTTCAGAAAACGCTATGCGATGCCGACACCGCGGGTGGCCGCGCTTGTCGGACTCGGA
ATGGAATCGCTGCAAATGCTGCTCATCCTCTTGATGGCCAAGCCGTTTTCTGATGCTTGGACGCTTGTGAGCATCATCGG
CATCCCGATGATATTGGTAAACGGGTCAGGGACTTTTATTTTTCTTTCGATCATTCAGTCGATTATCCGGAAGGAAGAAC
GGGCGAGAGCCCTTGAAACCCACAGGGTGCTGATGATTGCCGACCAGACGCTTCCGTTTTTCCGCCAGGGGCTGAATGAA
AGCTCATGCAAAAGCGTCGCCGCCATCATTCACAGGCAAACAGGAACGGACGCGGTATCGCTTACGGATAACGAAAAGAT
TTTGGCGCACGTCGGCGCGGGTGCCGACCATCATATTCCGTCTGAAAGCCTGATCACCGGATTGTCAAAACGCGTCATTA
AAACGGGTCATATTATGAAAGCGACATCAAAGGAAGAAATTGAATGCACGCACGATCCCTGTCCGCTGCATGCGGCGATC
GTATTGCCGCTGACGTCAAACGGCAAAACGATCGGGACGTTGAAAATGTACTTTAAAAGCCCGTCAGGTTTAAGCCGGGT
TGAAGAAGAGCTTGCAGAAGGACTCGCCATGCTGTTTTCCACCCAGCTTGAACTCGGCGAGGCGGAACTGCAGAGCAAAT
TGCTGAAAGACGCAGAAATAAAGGCGCTTCAGGCACAGGTCAATCCGCATTTTCTGTTTAATGCGATCAATACGATTTCT
GCTCTTTGCCGTACGGATGTGGAAAAAACCCGAAAGCTTCTGCTGCAGCTCAGCGTCTATTTCCGTTCCAATCTGCAGGG
GGCAAGGCAGCTGCTCATCCCGCTTTCTAAAGAACTGAACCATCTGCAGGCGTATTTATCATTGGAGCAGGCCCGTTTTC
CCGGGAAATATAAAATCAGTCTTGAAATCGAACGCGGTTTGGAGGACATCGAAATTCCTCCTTTTGTGCTGCAGATTCTC
GTCGAAAATGCGCTCCGCCATGCATTTTCAAGAAAGCAGGACAGCTGTGCCGTCAATGTCAGCGTGGTATCCGCCGGTCA
GTCGGTTTTAATGCGGGTTGGAGATAACGGGCGAGGAATTGATCCGGAATTGCTGTCCGTGCTCGGAAACCGTCCGCTGC
CGTCTAAAGAAGGGACGGGAACCGCGCTTTACAATTTAAATCAGCGGCTGATCGGGCTGTTCGGCCCCAAAGCAGCCCTG
CGATTGGAAAGTGAGCCCGGCAAAGGTACGGACGTATCATTTGAGCTGCCTTTGAAACTGATGACTAAAGGAGAAGAACA
TGCTGAAGGTGTTAATCGTTGA

Upstream 100 bases:

>100_bases
TGTTTTCAGATGATTTGAAAAAAACAGGCAGGTTTGTGTCAGATTCTGTCTCAGGCTCTAAAACGTGATAAAATAAAATT
TGAAAGAACAGGTGAAAAGT

Downstream 100 bases:

>100_bases
TGATGAAATGCTGGCAAGAGATGAATTAGCTTATTTGCTGAAACGGACGAATGAAGTAAGTGACATAAACGAAGCTGAAA
ATATTGAATCCGCTTTTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MLHLIIMMLERVGIIVILGFVLAHTRLFRQALQQPESYKGKAVLISIFSLFSIISNYTGIEIQRNTIMNNDWVFQINPSG
SIANTRIMGVEIGGLLGGPYVGIGVGILAGLHRLSLGGATAVSCAVSSVLAGILSGWIGRYFRKRYAMPTPRVAALVGLG
MESLQMLLILLMAKPFSDAWTLVSIIGIPMILVNGSGTFIFLSIIQSIIRKEERARALETHRVLMIADQTLPFFRQGLNE
SSCKSVAAIIHRQTGTDAVSLTDNEKILAHVGAGADHHIPSESLITGLSKRVIKTGHIMKATSKEEIECTHDPCPLHAAI
VLPLTSNGKTIGTLKMYFKSPSGLSRVEEELAEGLAMLFSTQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAINTIS
ALCRTDVEKTRKLLLQLSVYFRSNLQGARQLLIPLSKELNHLQAYLSLEQARFPGKYKISLEIERGLEDIEIPPFVLQIL
VENALRHAFSRKQDSCAVNVSVVSAGQSVLMRVGDNGRGIDPELLSVLGNRPLPSKEGTGTALYNLNQRLIGLFGPKAAL
RLESEPGKGTDVSFELPLKLMTKGEEHAEGVNR

Sequences:

>Translated_593_residues
MLHLIIMMLERVGIIVILGFVLAHTRLFRQALQQPESYKGKAVLISIFSLFSIISNYTGIEIQRNTIMNNDWVFQINPSG
SIANTRIMGVEIGGLLGGPYVGIGVGILAGLHRLSLGGATAVSCAVSSVLAGILSGWIGRYFRKRYAMPTPRVAALVGLG
MESLQMLLILLMAKPFSDAWTLVSIIGIPMILVNGSGTFIFLSIIQSIIRKEERARALETHRVLMIADQTLPFFRQGLNE
SSCKSVAAIIHRQTGTDAVSLTDNEKILAHVGAGADHHIPSESLITGLSKRVIKTGHIMKATSKEEIECTHDPCPLHAAI
VLPLTSNGKTIGTLKMYFKSPSGLSRVEEELAEGLAMLFSTQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAINTIS
ALCRTDVEKTRKLLLQLSVYFRSNLQGARQLLIPLSKELNHLQAYLSLEQARFPGKYKISLEIERGLEDIEIPPFVLQIL
VENALRHAFSRKQDSCAVNVSVVSAGQSVLMRVGDNGRGIDPELLSVLGNRPLPSKEGTGTALYNLNQRLIGLFGPKAAL
RLESEPGKGTDVSFELPLKLMTKGEEHAEGVNR
>Mature_593_residues
MLHLIIMMLERVGIIVILGFVLAHTRLFRQALQQPESYKGKAVLISIFSLFSIISNYTGIEIQRNTIMNNDWVFQINPSG
SIANTRIMGVEIGGLLGGPYVGIGVGILAGLHRLSLGGATAVSCAVSSVLAGILSGWIGRYFRKRYAMPTPRVAALVGLG
MESLQMLLILLMAKPFSDAWTLVSIIGIPMILVNGSGTFIFLSIIQSIIRKEERARALETHRVLMIADQTLPFFRQGLNE
SSCKSVAAIIHRQTGTDAVSLTDNEKILAHVGAGADHHIPSESLITGLSKRVIKTGHIMKATSKEEIECTHDPCPLHAAI
VLPLTSNGKTIGTLKMYFKSPSGLSRVEEELAEGLAMLFSTQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAINTIS
ALCRTDVEKTRKLLLQLSVYFRSNLQGARQLLIPLSKELNHLQAYLSLEQARFPGKYKISLEIERGLEDIEIPPFVLQIL
VENALRHAFSRKQDSCAVNVSVVSAGQSVLMRVGDNGRGIDPELLSVLGNRPLPSKEGTGTALYNLNQRLIGLFGPKAAL
RLESEPGKGTDVSFELPLKLMTKGEEHAEGVNR

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=580, Percent_Identity=33.6206896551724, Blast_Score=317, Evalue=2e-87,
Organism=Escherichia coli, GI1788446, Length=584, Percent_Identity=33.5616438356164, Blast_Score=298, Evalue=5e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64732; Mature: 64732

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLIIMMLERVGIIVILGFVLAHTRLFRQALQQPESYKGKAVLISIFSLFSIISNYTGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC
EIQRNTIMNNDWVFQINPSGSIANTRIMGVEIGGLLGGPYVGIGVGILAGLHRLSLGGAT
EEEECEECCCCEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHH
AVSCAVSSVLAGILSGWIGRYFRKRYAMPTPRVAALVGLGMESLQMLLILLMAKPFSDAW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
TLVSIIGIPMILVNGSGTFIFLSIIQSIIRKEERARALETHRVLMIADQTLPFFRQGLNE
HHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHCCCH
SSCKSVAAIIHRQTGTDAVSLTDNEKILAHVGAGADHHIPSESLITGLSKRVIKTGHIMK
HHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEE
ATSKEEIECTHDPCPLHAAIVLPLTSNGKTIGTLKMYFKSPSGLSRVEEELAEGLAMLFS
CCCCCCCEECCCCCCCEEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
TQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAINTISALCRTDVEKTRKLLLQLSVY
HHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSNLQGARQLLIPLSKELNHLQAYLSLEQARFPGKYKISLEIERGLEDIEIPPFVLQIL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
VENALRHAFSRKQDSCAVNVSVVSAGQSVLMRVGDNGRGIDPELLSVLGNRPLPSKEGTG
HHHHHHHHHHCCCCCCEEEEEEECCCHHHHEEECCCCCCCCHHHHHHHCCCCCCCCCCCC
TALYNLNQRLIGLFGPKAALRLESEPGKGTDVSFELPLKLMTKGEEHAEGVNR
CEEEECCHHHHHHCCCCEEEEEECCCCCCCCEEEECCHHHHCCCCHHHCCCCC
>Mature Secondary Structure
MLHLIIMMLERVGIIVILGFVLAHTRLFRQALQQPESYKGKAVLISIFSLFSIISNYTGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC
EIQRNTIMNNDWVFQINPSGSIANTRIMGVEIGGLLGGPYVGIGVGILAGLHRLSLGGAT
EEEECEECCCCEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHH
AVSCAVSSVLAGILSGWIGRYFRKRYAMPTPRVAALVGLGMESLQMLLILLMAKPFSDAW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
TLVSIIGIPMILVNGSGTFIFLSIIQSIIRKEERARALETHRVLMIADQTLPFFRQGLNE
HHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHCCCH
SSCKSVAAIIHRQTGTDAVSLTDNEKILAHVGAGADHHIPSESLITGLSKRVIKTGHIMK
HHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEE
ATSKEEIECTHDPCPLHAAIVLPLTSNGKTIGTLKMYFKSPSGLSRVEEELAEGLAMLFS
CCCCCCCEECCCCCCCEEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
TQLELGEAELQSKLLKDAEIKALQAQVNPHFLFNAINTISALCRTDVEKTRKLLLQLSVY
HHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSNLQGARQLLIPLSKELNHLQAYLSLEQARFPGKYKISLEIERGLEDIEIPPFVLQIL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
VENALRHAFSRKQDSCAVNVSVVSAGQSVLMRVGDNGRGIDPELLSVLGNRPLPSKEGTG
HHHHHHHHHHCCCCCCEEEEEEECCCHHHHEEECCCCCCCCHHHHHHHCCCCCCCCCCCC
TALYNLNQRLIGLFGPKAALRLESEPGKGTDVSFELPLKLMTKGEEHAEGVNR
CEEEECCHHHHHHCCCCEEEEEECCCCCCCCEEEECCHHHHCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]