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The map label for this gene is ysnA [H]

Identifier: 154686971

GI number: 154686971

Start: 2664045

End: 2664632

Strand: Reverse

Name: ysnA [H]

Synonym: RBAM_025430

Alternate gene names: 154686971

Gene position: 2664632-2664045 (Counterclockwise)

Preceding gene: 154686972

Following gene: 154686970

Centisome position: 68.0

GC content: 47.79

Gene sequence:

>588_bases
GTGAAAGAAGCCATTATTGCGACACACAATCAGGGAAAAGTGAAAGAATTCAAGGAAATTCTCGAACCGAAAGGCTACAG
CGTCTCTTCTTTGGCGGAAATCGGATTTACGGAAGAAATTGAAGAAACCGGACATACCTTTGAAGAAAACGCCATCTTAA
AAGCGGAAGCCGTGGCAAAAGCCGTCAACAAAATGGTCATTGCAGACGACTCCGGTTTATCGGTGGACAACCTTGGAGGC
AGACCGGGCGTTTATTCAGCCCGTTATGCCGGAGAAGCAAAAGATGATAAGGCGAATATGGACAAGGTGCTGTCAGAATT
AAAAGGCATCGAAAAAGAGCAGCGCACGGCCCGTTTCCGCTGCGCCCTTGCCGTCAGCATGCCGGGGCAGGAAACAAAAA
CGGTCGAAGGTCATGTTGAAGGGTATATTGCGGAAGGACCCGAGGGGGATAACGGGTTCGGCTATGATCCCATTTTTATT
GTAAAAGATAAAGATAAAACCATGGCCCAGCTGACAAGCGCTGAGAAAAACAAAATCAGCCACAGGGCTGAGGCGCTCAA
GAAACTGTCAAAGCTGCTTGATTCATAA

Upstream 100 bases:

>100_bases
GCCTTGCCGAAAAAGGAATCCAGACGCTTATTCAAAAGCAAAAAGAAGTGCTGGGAGAAACATTGCCTGAACTGAAATAA
GAAAGAGAGGCCTGATCACC

Downstream 100 bases:

>100_bases
GGGGGAGCGTATGCAATGAAAGTGCTGATAATAAGTGACAGTCACGGCCTTGAAGACGAGCTGGAGACGATTGCAAAGCG
GCACGAAGAGGAAGCGGATC

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKEAIIATHNQGKVKEFKEILEPKGYSVSSLAEIGFTEEIEETGHTFEENAILKAEAVAKAVNKMVIADDSGLSVDNLGG
RPGVYSARYAGEAKDDKANMDKVLSELKGIEKEQRTARFRCALAVSMPGQETKTVEGHVEGYIAEGPEGDNGFGYDPIFI
VKDKDKTMAQLTSAEKNKISHRAEALKKLSKLLDS

Sequences:

>Translated_195_residues
MKEAIIATHNQGKVKEFKEILEPKGYSVSSLAEIGFTEEIEETGHTFEENAILKAEAVAKAVNKMVIADDSGLSVDNLGG
RPGVYSARYAGEAKDDKANMDKVLSELKGIEKEQRTARFRCALAVSMPGQETKTVEGHVEGYIAEGPEGDNGFGYDPIFI
VKDKDKTMAQLTSAEKNKISHRAEALKKLSKLLDS
>Mature_195_residues
MKEAIIATHNQGKVKEFKEILEPKGYSVSSLAEIGFTEEIEETGHTFEENAILKAEAVAKAVNKMVIADDSGLSVDNLGG
RPGVYSARYAGEAKDDKANMDKVLSELKGIEKEQRTARFRCALAVSMPGQETKTVEGHVEGYIAEGPEGDNGFGYDPIFI
VKDKDKTMAQLTSAEKNKISHRAEALKKLSKLLDS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=194, Percent_Identity=28.8659793814433, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI31657144, Length=148, Percent_Identity=30.4054054054054, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1789324, Length=192, Percent_Identity=47.3958333333333, Blast_Score=164, Evalue=3e-42,
Organism=Drosophila melanogaster, GI19920712, Length=191, Percent_Identity=30.8900523560209, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21250; Mature: 21250

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEAIIATHNQGKVKEFKEILEPKGYSVSSLAEIGFTEEIEETGHTFEENAILKAEAVAK
CCCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHH
AVNKMVIADDSGLSVDNLGGRPGVYSARYAGEAKDDKANMDKVLSELKGIEKEQRTARFR
HHHHEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
CALAVSMPGQETKTVEGHVEGYIAEGPEGDNGFGYDPIFIVKDKDKTMAQLTSAEKNKIS
EEEEECCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
HRAEALKKLSKLLDS
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEAIIATHNQGKVKEFKEILEPKGYSVSSLAEIGFTEEIEETGHTFEENAILKAEAVAK
CCCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHH
AVNKMVIADDSGLSVDNLGGRPGVYSARYAGEAKDDKANMDKVLSELKGIEKEQRTARFR
HHHHEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
CALAVSMPGQETKTVEGHVEGYIAEGPEGDNGFGYDPIFIVKDKDKTMAQLTSAEKNKIS
EEEEECCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
HRAEALKKLSKLLDS
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377; 1624460 [H]