Click here to switch to the map view.

The map label for this gene is obgE

Identifier: 154686927

GI number: 154686927

Start: 2617159

End: 2618445

Strand: Reverse

Name: obgE

Synonym: RBAM_024970

Alternate gene names: 154686927

Gene position: 2618445-2617159 (Counterclockwise)

Preceding gene: 154686928

Following gene: 154686926

Centisome position: 66.82

GC content: 51.98

Gene sequence:

>1287_bases
ATGTTTGTAGATCAGGTGAAAGTATATGTAAAAGGCGGCGACGGCGGTAACGGAATGGTTGCGTTCCGCCGTGAAAAATA
TGTGCCGAAAGGCGGGCCTGCCGGCGGTGACGGAGGTAATGGAGGCGACGTCGTTTTTGAGGTTGATGAAGGACTGCGCA
CGCTCATGGACTTCCGGTACCAGCGGCATTTCAAAGCGATACGCGGCGAGCACGGCATGTCTAAAAACCAGCACGGCAGA
AATGCGGACGATATGGTTGTTAAAGTTCCGCCCGGCACAGTCGTAACGGATGACGATACAAAACAGGTCATTGCCGATCT
GACTGAGCATGGGCAGCGTGCCGTCATCGCAAAAGGCGGACGCGGCGGACGCGGAAATACCCGCTTTGCGACACCGGCCA
ACCCGGCACCGCAGCTGTCAGAGCACGGAGAGCCCGGAAAAGAGCGCTATATCGTGCTTGAACTGAAAGTGCTTGCAGAC
GTAGGTCTCGTCGGCTTCCCGAGCGTCGGAAAATCTACGCTTCTGTCTGTCGTTTCATCGGCAAAGCCGAAAATCGCCGA
TTATCATTTTACAACGCTTGTTCCGAATCTGGGCATGGTGGAAACGGATGACGGAAGAAGCTTCGTCATGGCGGATCTGC
CCGGTTTGATTGAAGGAGCGCATGAAGGAGTCGGCTTAGGCCACCAATTTCTCCGCCATATCGAACGGACGCGCGTCATC
GTTCACGTCATTGACATGTCAGCGATGGAAGGCCGTGATCCGTATGAGGATTATGTCACCATTAATCAGGAGCTCAGTGA
ATATAATCTGCGGCTGACGGAGCGTCCGCAAATTATCGTTGCGAATAAAATGGACATGCCCGAAGCGGCTGAAAATCTTA
AAGCGTTTAAAGAAAAGCTTCAGGATGACCATCCTGTCTTCCCGATCAGCGCGGTGACGAGAGAAGGGCTCCGCGATCTT
CTGTTTGAAGTCGCCAACCAGCTGGAAACAACGCCTGAATTCCCGCTGTATGATGAAGAAGAACTGGCGGAAAACCGCGT
AATGTACACGATGGAAGACGAAGAAATTCCATTTAACATTACCCGTGATCCGGACGGTGCGTTTGTGCTTTCAGGTGACA
GTCTGGAACGCCTCTTTAAAATGACTGATTTCTCCCGTGACGAATCCGTCAAGCGTTTTGCAAGACAGATGCGCGGTATG
GGCGTTGATGAAGCGCTCAGAGAACGCGGTGCTAAAGACGGCGATATCATCCGGCTTCTGGAATTTGAATTTGAATTTAT
TGATTAA

Upstream 100 bases:

>100_bases
GAGGACTTTGATGTCATGCAATTTGAGCTGACCGGCCATGAATGTGTGGCCGAAATTGGAATGAACTAGCGGTTTTTTAC
GGTTTAGAACGGAGGATATT

Downstream 100 bases:

>100_bases
AAAAACGGAGAGCTTGCAATGCAGGCTCTCTGATGTAAAAGGGAGGGGTGCAGGTGAAAGAAGAGACATTTTATTTAGTG
CGTGAAGACGTTCTGCCTGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGNGGDVVFEVDEGLRTLMDFRYQRHFKAIRGEHGMSKNQHGR
NADDMVVKVPPGTVVTDDDTKQVIADLTEHGQRAVIAKGGRGGRGNTRFATPANPAPQLSEHGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMSAMEGRDPYEDYVTINQELSEYNLRLTERPQIIVANKMDMPEAAENLKAFKEKLQDDHPVFPISAVTREGLRDL
LFEVANQLETTPEFPLYDEEELAENRVMYTMEDEEIPFNITRDPDGAFVLSGDSLERLFKMTDFSRDESVKRFARQMRGM
GVDEALRERGAKDGDIIRLLEFEFEFID

Sequences:

>Translated_428_residues
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGNGGDVVFEVDEGLRTLMDFRYQRHFKAIRGEHGMSKNQHGR
NADDMVVKVPPGTVVTDDDTKQVIADLTEHGQRAVIAKGGRGGRGNTRFATPANPAPQLSEHGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMSAMEGRDPYEDYVTINQELSEYNLRLTERPQIIVANKMDMPEAAENLKAFKEKLQDDHPVFPISAVTREGLRDL
LFEVANQLETTPEFPLYDEEELAENRVMYTMEDEEIPFNITRDPDGAFVLSGDSLERLFKMTDFSRDESVKRFARQMRGM
GVDEALRERGAKDGDIIRLLEFEFEFID
>Mature_428_residues
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGNGGDVVFEVDEGLRTLMDFRYQRHFKAIRGEHGMSKNQHGR
NADDMVVKVPPGTVVTDDDTKQVIADLTEHGQRAVIAKGGRGGRGNTRFATPANPAPQLSEHGEPGKERYIVLELKVLAD
VGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMSAMEGRDPYEDYVTINQELSEYNLRLTERPQIIVANKMDMPEAAENLKAFKEKLQDDHPVFPISAVTREGLRDL
LFEVANQLETTPEFPLYDEEELAENRVMYTMEDEEIPFNITRDPDGAFVLSGDSLERLFKMTDFSRDESVKRFARQMRGM
GVDEALRERGAKDGDIIRLLEFEFEFID

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=347, Percent_Identity=42.0749279538905, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI111955139, Length=383, Percent_Identity=35.2480417754569, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI111955063, Length=260, Percent_Identity=36.9230769230769, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=38.0165289256198, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=37.7952755905512, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789574, Length=356, Percent_Identity=48.0337078651685, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.0579710144928, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790615, Length=129, Percent_Identity=31.0077519379845, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17508313, Length=333, Percent_Identity=40.8408408408408, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=326, Percent_Identity=30.9815950920245, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=36.4406779661017, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=36.4406779661017, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=30.9352517985612, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=195, Percent_Identity=37.9487179487179, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=38.8888888888889, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=34.9206349206349, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20129375, Length=324, Percent_Identity=42.9012345679012, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24585318, Length=309, Percent_Identity=39.1585760517799, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=37.007874015748, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356473, Length=126, Percent_Identity=37.3015873015873, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=35.15625, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=35.15625, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=35.15625, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BACA2 (A7Z781)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422088.1
- ProteinModelPortal:   A7Z781
- SMR:   A7Z781
- STRING:   A7Z781
- EnsemblBacteria:   EBBACT00000005179
- GeneID:   5460207
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_024970
- eggNOG:   COG0536
- GeneTree:   EBGT00050000000577
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   BAMY326423:RBAM_024970-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47663; Mature: 47663

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGNGGDVVFEVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
QRHFKAIRGEHGMSKNQHGRNADDMVVKVPPGTVVTDDDTKQVIADLTEHGQRAVIAKGG
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNTRFATPANPAPQLSEHGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEECCCCCCCCCHHHCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
AKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCCCCEEHHHHCCCCCCEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSAMEGRDPYEDYVTINQELSEYNLRLTERPQIIVANKMDMPEAAENLKAFKEKL
EEEECHHHHCCCCCHHHHEEHHHHHHHCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHH
QDDHPVFPISAVTREGLRDLLFEVANQLETTPEFPLYDEEELAENRVMYTMEDEEIPFNI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEEEECCCCCEEE
TRDPDGAFVLSGDSLERLFKMTDFSRDESVKRFARQMRGMGVDEALRERGAKDGDIIRLL
ECCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EFEFEFID
EEEEEECC
>Mature Secondary Structure
MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGNGGDVVFEVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
QRHFKAIRGEHGMSKNQHGRNADDMVVKVPPGTVVTDDDTKQVIADLTEHGQRAVIAKGG
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNTRFATPANPAPQLSEHGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEECCCCCCCCCHHHCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
AKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCCCCEEHHHHCCCCCCEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSAMEGRDPYEDYVTINQELSEYNLRLTERPQIIVANKMDMPEAAENLKAFKEKL
EEEECHHHHCCCCCHHHHEEHHHHHHHCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHH
QDDHPVFPISAVTREGLRDLLFEVANQLETTPEFPLYDEEELAENRVMYTMEDEEIPFNI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEEEECCCCCEEE
TRDPDGAFVLSGDSLERLFKMTDFSRDESVKRFARQMRGMGVDEALRERGAKDGDIIRLL
ECCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EFEFEFID
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA