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The map label for this gene is holA [H]

Identifier: 154686816

GI number: 154686816

Start: 2505625

End: 2506647

Strand: Reverse

Name: holA [H]

Synonym: RBAM_023860

Alternate gene names: 154686816

Gene position: 2506647-2505625 (Counterclockwise)

Preceding gene: 154686817

Following gene: 154686814

Centisome position: 63.97

GC content: 44.28

Gene sequence:

>1023_bases
ATGGTATTTGATGTTTGGAAAGCCCTGAAAAAAGGGGATGTCCGCTCCGTTTATTGCTTATACGGAAAAGAAACGTATCT
GCTCCAAGAAACTGTCAGCCGGATCAGACAAGCTGTCGTTGATGAGGAGACAAAGGATTTTAACCTGTCTGTTTTTGATC
TTGAAGAAGATCCGCTTGACCAGGCCGTAACCGATGCGGAAACGTTTCCGTTTATGGGAGAGAAGCGGCTGGTCATCGTA
AAAAATCCGTCTTTTTTAACAGGGGAAAAAAAGAAAGAAAAAATAGAGCATAATACAGCCGCTCTGGAGACTTATCTGAA
GGAGCCTGCGCCTTATACGGTCTTTGTGATTGTGGCTCCGTACGAGAAGCTGGACGAACGGAAAAAGCTGACGAAAGCGC
TGAAGCAAAAAGCCCTTATGATTGAAGCTAAGGAGCTGAATGCAAAGGAGACGACTGATTTTACGATTAATCTGGCGAAA
TCCGAAAATAAAATGATCGATACAGAAGCTGCCGAGCATTTGGTTCTGCTTGCAAACGGCCATCTGTCATCCATATATCA
GGAAATACAAAAACTCTCCGCCTACACCGGTGACAGACATGAGATCACACTTGAAGATGTCCGGGAGCTCGTCGCAAGAA
GTTTGGAGCAGAATATTTTTGAGCTGATCAACAAAATCGTGAACCGAAAACGGACGGAAAGTCTTCAAATATTTTATGAT
CTTTTAAAACAAAACGAAGAACCGATCAAAATTATGGCGCTGATCGCCAACCAATTCCGTCTGATTATGCAGACAAAGTA
TTTTGCGGGACAAGGATACGGCCAAAAGCAAATCGCTTCCAACTTAAAGGTGCACCCCTTCCGGGTAAAACTGGCGATGG
ATCAGGCGAGGCTTTTTTCTGAAGAAGAGCTGCGGCGTATTATAGAAAGACTCGCGGTGATGGATTATGAAATGAAAACG
GGGAAAAAGGACAAGCAGCTCTTGCTGGAACTCTTTCTCCTTGAGCTTCTCCGGACTGAATGA

Upstream 100 bases:

>100_bases
ATTATAAATGAGGAAGCTGTCCTTAAAGCTTCCTCTTTACTATTTGCCGAACTCAATTTAGGATAGAAGGGGATCAAGAA
AGAGAGGAAGTCATACGATC

Downstream 100 bases:

>100_bases
AAAAAACGATCCCCGTTAAAGGGATCGTTTTTGTATTATGCAGAAAGTCCGTTCACTTGTTTCGCAAGTCTAGATTTGTA
TCGAGCTGCGGCATTTTTGT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MVFDVWKALKKGDVRSVYCLYGKETYLLQETVSRIRQAVVDEETKDFNLSVFDLEEDPLDQAVTDAETFPFMGEKRLVIV
KNPSFLTGEKKKEKIEHNTAALETYLKEPAPYTVFVIVAPYEKLDERKKLTKALKQKALMIEAKELNAKETTDFTINLAK
SENKMIDTEAAEHLVLLANGHLSSIYQEIQKLSAYTGDRHEITLEDVRELVARSLEQNIFELINKIVNRKRTESLQIFYD
LLKQNEEPIKIMALIANQFRLIMQTKYFAGQGYGQKQIASNLKVHPFRVKLAMDQARLFSEEELRRIIERLAVMDYEMKT
GKKDKQLLLELFLLELLRTE

Sequences:

>Translated_340_residues
MVFDVWKALKKGDVRSVYCLYGKETYLLQETVSRIRQAVVDEETKDFNLSVFDLEEDPLDQAVTDAETFPFMGEKRLVIV
KNPSFLTGEKKKEKIEHNTAALETYLKEPAPYTVFVIVAPYEKLDERKKLTKALKQKALMIEAKELNAKETTDFTINLAK
SENKMIDTEAAEHLVLLANGHLSSIYQEIQKLSAYTGDRHEITLEDVRELVARSLEQNIFELINKIVNRKRTESLQIFYD
LLKQNEEPIKIMALIANQFRLIMQTKYFAGQGYGQKQIASNLKVHPFRVKLAMDQARLFSEEELRRIIERLAVMDYEMKT
GKKDKQLLLELFLLELLRTE
>Mature_340_residues
MVFDVWKALKKGDVRSVYCLYGKETYLLQETVSRIRQAVVDEETKDFNLSVFDLEEDPLDQAVTDAETFPFMGEKRLVIV
KNPSFLTGEKKKEKIEHNTAALETYLKEPAPYTVFVIVAPYEKLDERKKLTKALKQKALMIEAKELNAKETTDFTINLAK
SENKMIDTEAAEHLVLLANGHLSSIYQEIQKLSAYTGDRHEITLEDVRELVARSLEQNIFELINKIVNRKRTESLQIFYD
LLKQNEEPIKIMALIANQFRLIMQTKYFAGQGYGQKQIASNLKVHPFRVKLAMDQARLFSEEELRRIIERLAVMDYEMKT
GKKDKQLLLELFLLELLRTE

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 39506; Mature: 39506

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFDVWKALKKGDVRSVYCLYGKETYLLQETVSRIRQAVVDEETKDFNLSVFDLEEDPLD
CCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHH
QAVTDAETFPFMGEKRLVIVKNPSFLTGEKKKEKIEHNTAALETYLKEPAPYTVFVIVAP
HHHHCHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
YEKLDERKKLTKALKQKALMIEAKELNAKETTDFTINLAKSENKMIDTEAAEHLVLLANG
HHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCEEEEEECCCCCEECHHHHCEEEEEECC
HLSSIYQEIQKLSAYTGDRHEITLEDVRELVARSLEQNIFELINKIVNRKRTESLQIFYD
CHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLKQNEEPIKIMALIANQFRLIMQTKYFAGQGYGQKQIASNLKVHPFRVKLAMDQARLFS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEEHHHHHHCC
EEELRRIIERLAVMDYEMKTGKKDKQLLLELFLLELLRTE
HHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVFDVWKALKKGDVRSVYCLYGKETYLLQETVSRIRQAVVDEETKDFNLSVFDLEEDPLD
CCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHH
QAVTDAETFPFMGEKRLVIVKNPSFLTGEKKKEKIEHNTAALETYLKEPAPYTVFVIVAP
HHHHCHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
YEKLDERKKLTKALKQKALMIEAKELNAKETTDFTINLAKSENKMIDTEAAEHLVLLANG
HHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCEEEEEECCCCCEECHHHHCEEEEEECC
HLSSIYQEIQKLSAYTGDRHEITLEDVRELVARSLEQNIFELINKIVNRKRTESLQIFYD
CHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLKQNEEPIKIMALIANQFRLIMQTKYFAGQGYGQKQIASNLKVHPFRVKLAMDQARLFS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEEHHHHHHCC
EEELRRIIERLAVMDYEMKTGKKDKQLLLELFLLELLRTE
HHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]