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The map label for this gene is yqgN [H]

Identifier: 154686751

GI number: 154686751

Start: 2444586

End: 2445140

Strand: Reverse

Name: yqgN [H]

Synonym: RBAM_023210

Alternate gene names: 154686751

Gene position: 2445140-2444586 (Counterclockwise)

Preceding gene: 154686752

Following gene: 154686750

Centisome position: 62.4

GC content: 49.73

Gene sequence:

>555_bases
GTGAAAGCACAAATCAGAACCGCTATCAAAGCAAAGCTTTCTGACATGACAGAAAGTGAATGGGAGAAAAAATGCCGCAG
CATGCGTGAAACGCTGTTTTCTTTAAAAGAATGGAAACAGGCCCGCGTGATCGCCGTTACCATCTCGACACGCCTGGAAA
TTCCGACACAGCCGATTATTGAACAGGCCTGGAAAGAGAAAAAACAAGTCTGTATCCCAAAATGCTTTCCGCAGACGGGA
GCGATGGAGTTCCGTACATTTTCTGCGTATGATCAGCTGGAAACCGTATATGCGGGCCTCAGTGAACCGATCGAGAGCCT
GACGGAAAAAGCCGCCCAAAAAGACATTGACCTTGTGATTGTGCCCGGCGTGGCTTTTGACCGGGAAGGCTTCAGAATCG
GATACGGCGGAGGATATTATGATCGGTACCTCCCCGGTTATAAAGGCCGTACCGTGTCGCTTCTCTTTGACTGCCAGCTG
ACAGACCGCATTCCCCGTATGCCCCACGATATTCCGGTCGATATGATCGTGACTGAATCTGAAACCATCGCTTAA

Upstream 100 bases:

>100_bases
GTTACACCGTGAAACAAAATAAGCTGTTTAAAACAGCGGAAAAAGCTGGAGCTTTCAATAAAGTTCTGGCTTTTTTGTCT
TTCAGGGAGGTTTGAGAAAC

Downstream 100 bases:

>100_bases
TCGCATAAAAAACTTCTTGCACCGGAATAATTCTCGCTGTTTGACAAACGATAGGGGCAGGAGGGATAAGATGAAAAAAT
TGTTGATCTACTCATTATGC

Product: YqgN

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKAQIRTAIKAKLSDMTESEWEKKCRSMRETLFSLKEWKQARVIAVTISTRLEIPTQPIIEQAWKEKKQVCIPKCFPQTG
AMEFRTFSAYDQLETVYAGLSEPIESLTEKAAQKDIDLVIVPGVAFDREGFRIGYGGGYYDRYLPGYKGRTVSLLFDCQL
TDRIPRMPHDIPVDMIVTESETIA

Sequences:

>Translated_184_residues
MKAQIRTAIKAKLSDMTESEWEKKCRSMRETLFSLKEWKQARVIAVTISTRLEIPTQPIIEQAWKEKKQVCIPKCFPQTG
AMEFRTFSAYDQLETVYAGLSEPIESLTEKAAQKDIDLVIVPGVAFDREGFRIGYGGGYYDRYLPGYKGRTVSLLFDCQL
TDRIPRMPHDIPVDMIVTESETIA
>Mature_184_residues
MKAQIRTAIKAKLSDMTESEWEKKCRSMRETLFSLKEWKQARVIAVTISTRLEIPTQPIIEQAWKEKKQVCIPKCFPQTG
AMEFRTFSAYDQLETVYAGLSEPIESLTEKAAQKDIDLVIVPGVAFDREGFRIGYGGGYYDRYLPGYKGRTVSLLFDCQL
TDRIPRMPHDIPVDMIVTESETIA

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=194, Percent_Identity=25.7731958762887, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789278, Length=146, Percent_Identity=35.6164383561644, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17510857, Length=195, Percent_Identity=27.6923076923077, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161077430, Length=193, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 21037; Mature: 21037

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAQIRTAIKAKLSDMTESEWEKKCRSMRETLFSLKEWKQARVIAVTISTRLEIPTQPII
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCHHH
EQAWKEKKQVCIPKCFPQTGAMEFRTFSAYDQLETVYAGLSEPIESLTEKAAQKDIDLVI
HHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VPGVAFDREGFRIGYGGGYYDRYLPGYKGRTVSLLFDCQLTDRIPRMPHDIPVDMIVTES
ECCEEECCCCCEEECCCCCHHHCCCCCCCCEEEEEEECCHHHCCCCCCCCCCCEEEEECC
ETIA
CCCC
>Mature Secondary Structure
MKAQIRTAIKAKLSDMTESEWEKKCRSMRETLFSLKEWKQARVIAVTISTRLEIPTQPII
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCHHH
EQAWKEKKQVCIPKCFPQTGAMEFRTFSAYDQLETVYAGLSEPIESLTEKAAQKDIDLVI
HHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VPGVAFDREGFRIGYGGGYYDRYLPGYKGRTVSLLFDCQLTDRIPRMPHDIPVDMIVTES
ECCEEECCCCCEEECCCCCHHHCCCCCCCCEEEEEEECCHHHCCCCCCCCCCCEEEEECC
ETIA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]