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The map label for this gene is sipS [H]

Identifier: 154686575

GI number: 154686575

Start: 2237038

End: 2237598

Strand: Reverse

Name: sipS [H]

Synonym: RBAM_021440

Alternate gene names: 154686575

Gene position: 2237598-2237038 (Counterclockwise)

Preceding gene: 154686576

Following gene: 154686574

Centisome position: 57.1

GC content: 46.17

Gene sequence:

>561_bases
TTGAAATCAGAAAAAGAAAAAACTTCTAAAAAAAGCGCCGTACTTGATTGGGCGAAAGCCATTATCATCGCTGTCGTTCT
GGCACTGCTCATCCGAAACTTTTTATTTGCCCCTTATCTCGTTGATGGAAGATCAATGGATCCGACGCTGCATGACCGCG
AGAGAATCTTTGTCAATATGACGGTCAAATACATAAGCGACTTCAAACGCGGCCAGATCGTCGTTCTGAACGGAGAAAAC
GAGCACTATGTCAAGCGGATTATCGGACTTCCCGGCGACACGGTACAAATGAAAAACGACCAGCTGTACATCAACGGCAA
AAAAGTGTCCGAACCGTATTTAGCGGCAAATAAGCACAAGGCGAAGCAAGACGGCTATGACCGGCTGACAGAAGACTTCG
GCCCGGTGAAGGTGCCGGACGACAAATATTTCGTCATGGGTGATAACCGCAGAGAATCTATGGACAGCCGCAACGGCCTC
GGTCTTTTTACGAAAAAACAAATAGCGGGCACATCAAAATTCGTCTTCTTCCCGTTTAATGAAATTCGCAAGACGAAATA
A

Upstream 100 bases:

>100_bases
TATAAAATGAAAAAAATGGATGAGGTGCGGGGCTTATTTGCCCTCTGTGCAGGGATTCATGGTAAAATAAAAACGACCAT
GGCTAATGGGAGGAAATCAC

Downstream 100 bases:

>100_bases
ACCGTACAGGCAGTTTTCTTCATGAGGAAAACTGCTTTTTTATATAAATTTATCTTTCCACCCTCAAAAACAGAACATAA
ATTCGTATATCTATTTAATA

Product: SipS

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKSEKEKTSKKSAVLDWAKAIIIAVVLALLIRNFLFAPYLVDGRSMDPTLHDRERIFVNMTVKYISDFKRGQIVVLNGEN
EHYVKRIIGLPGDTVQMKNDQLYINGKKVSEPYLAANKHKAKQDGYDRLTEDFGPVKVPDDKYFVMGDNRRESMDSRNGL
GLFTKKQIAGTSKFVFFPFNEIRKTK

Sequences:

>Translated_186_residues
MKSEKEKTSKKSAVLDWAKAIIIAVVLALLIRNFLFAPYLVDGRSMDPTLHDRERIFVNMTVKYISDFKRGQIVVLNGEN
EHYVKRIIGLPGDTVQMKNDQLYINGKKVSEPYLAANKHKAKQDGYDRLTEDFGPVKVPDDKYFVMGDNRRESMDSRNGL
GLFTKKQIAGTSKFVFFPFNEIRKTK
>Mature_186_residues
MKSEKEKTSKKSAVLDWAKAIIIAVVLALLIRNFLFAPYLVDGRSMDPTLHDRERIFVNMTVKYISDFKRGQIVVLNGEN
EHYVKRIIGLPGDTVQMKNDQLYINGKKVSEPYLAANKHKAKQDGYDRLTEDFGPVKVPDDKYFVMGDNRRESMDSRNGL
GLFTKKQIAGTSKFVFFPFNEIRKTK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21354; Mature: 21354

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSEKEKTSKKSAVLDWAKAIIIAVVLALLIRNFLFAPYLVDGRSMDPTLHDRERIFVNM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEEEEE
TVKYISDFKRGQIVVLNGENEHYVKRIIGLPGDTVQMKNDQLYINGKKVSEPYLAANKHK
EHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCCHHCCCCC
AKQDGYDRLTEDFGPVKVPDDKYFVMGDNRRESMDSRNGLGLFTKKQIAGTSKFVFFPFN
HHHCHHHHHHHCCCCEECCCCCEEEEECCHHHHCCCCCCCCEEEHHHHCCCCEEEEECHH
EIRKTK
HHCCCC
>Mature Secondary Structure
MKSEKEKTSKKSAVLDWAKAIIIAVVLALLIRNFLFAPYLVDGRSMDPTLHDRERIFVNM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEEEEE
TVKYISDFKRGQIVVLNGENEHYVKRIIGLPGDTVQMKNDQLYINGKKVSEPYLAANKHK
EHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCCHHCCCCC
AKQDGYDRLTEDFGPVKVPDDKYFVMGDNRRESMDSRNGLGLFTKKQIAGTSKFVFFPFN
HHHCHHHHHHHCCCCEECCCCCEEEEECCHHHHCCCCCCCCEEEHHHHCCCCEEEEECHH
EIRKTK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]