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The map label for this gene is resD [H]

Identifier: 154686557

GI number: 154686557

Start: 2221762

End: 2222484

Strand: Reverse

Name: resD [H]

Synonym: RBAM_021260

Alternate gene names: 154686557

Gene position: 2222484-2221762 (Counterclockwise)

Preceding gene: 154686558

Following gene: 154686556

Centisome position: 56.72

GC content: 47.58

Gene sequence:

>723_bases
ATGGATCAAACAAATGAAACTAAAATATTAGTAGTAGATGATGAAGCCAGAATTCGACGCCTTTTAAGAATGTACCTTGA
ACGGGAAAACTATGTGATTGAAGAAGCGGAAAACGGCGACGAGGCCATTAAAATGGGGCTGGCATCAGATTATGATCTGG
TGCTCTTGGATTTAATGATGCCGGGAACGGACGGAATCGAAGTATGCCGGCAGCTCAGAGAAAAAAAAGCGACGCCGATT
ATCATGCTGACGGCAAAAGGGGAAGAAGCCAACCGCGTTCAGGGGTTTGAAGCGGGTACGGACGATTATATCGTCAAGCC
TTTCAGCCCGAGAGAAGTGGTGCTTCGGGTAAAGGCGCTTTTAAGAAGGGCTTCCCAAACATCTTATCTGACAGCCAATA
CCCCGACAAAAAATGTGCTCGTCTTTTCGCATCTATCCATTGATCACGATGCTCACAGGGTGACTGCGGACGGCACGGAG
GTGAGCCTGACGCCGAAGGAATATGAACTGCTGTACTTCCTGGCGAAAACACCGGACAAAGTGTACGACAGGGAAAAGCT
TTTAAAAGAAGTGTGGCAGTATGAATTTTTCGGAGACCTCAGAACGGTGGACACCCATGTCAAACGGCTCCGTGAAAAAT
TAAATAAAGTGTCCCCGGGAGCGGCGAAAAAAATCGTCACCGTATGGGGAGTCGGATACAAATTTGAGGTAGGCGCTGAA
TGA

Upstream 100 bases:

>100_bases
ACTTCATTCGTACGCATAGATGCAAAAAGCCGATACAGTTCTCAAGCTGCCGCACAGTTTGTTAAAATGAAAGTAACAGA
AGGAAAGCAGGGGGAAAACG

Downstream 100 bases:

>100_bases
AGTTTTGGAAAAGCGTAGTAGGAAAGCTTTGGTTTACCATTCTTTCACTCGTGTTAATTGTTTTATTTATTTTAACGGTG
CTGCTTCTGGAATTTATAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDQTNETKILVVDDEARIRRLLRMYLERENYVIEEAENGDEAIKMGLASDYDLVLLDLMMPGTDGIEVCRQLREKKATPI
IMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLRRASQTSYLTANTPTKNVLVFSHLSIDHDAHRVTADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPGAAKKIVTVWGVGYKFEVGAE

Sequences:

>Translated_240_residues
MDQTNETKILVVDDEARIRRLLRMYLERENYVIEEAENGDEAIKMGLASDYDLVLLDLMMPGTDGIEVCRQLREKKATPI
IMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLRRASQTSYLTANTPTKNVLVFSHLSIDHDAHRVTADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPGAAKKIVTVWGVGYKFEVGAE
>Mature_240_residues
MDQTNETKILVVDDEARIRRLLRMYLERENYVIEEAENGDEAIKMGLASDYDLVLLDLMMPGTDGIEVCRQLREKKATPI
IMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLRRASQTSYLTANTPTKNVLVFSHLSIDHDAHRVTADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPGAAKKIVTVWGVGYKFEVGAE

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=42.2413793103448, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=41.1016949152542, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=35.9649122807018, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=36.2445414847162, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.9310344827586, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=37.280701754386, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=35.8078602620087, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.140350877193, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=37.8854625550661, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=36.3247863247863, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=33.1858407079646, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.8777292576419, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=32.3275862068966, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=34.1666666666667, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788191, Length=108, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=140, Percent_Identity=30, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=198, Percent_Identity=29.2929292929293, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788222, Length=115, Percent_Identity=33.9130434782609, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27444; Mature: 27444

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQTNETKILVVDDEARIRRLLRMYLERENYVIEEAENGDEAIKMGLASDYDLVLLDLMM
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCHHHHEECCCCCCCEEEEEECC
PGTDGIEVCRQLREKKATPIIMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKAL
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
LRRASQTSYLTANTPTKNVLVFSHLSIDHDAHRVTADGTEVSLTPKEYELLYFLAKTPDK
HHHCCCCCEEEECCCCCCEEEEEEECCCCCCCEEECCCCEEEECCCCEEEEEEEECCCHH
VYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPGAAKKIVTVWGVGYKFEVGAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCEEEEECCC
>Mature Secondary Structure
MDQTNETKILVVDDEARIRRLLRMYLERENYVIEEAENGDEAIKMGLASDYDLVLLDLMM
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEECCCCCHHHHEECCCCCCCEEEEEECC
PGTDGIEVCRQLREKKATPIIMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKAL
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
LRRASQTSYLTANTPTKNVLVFSHLSIDHDAHRVTADGTEVSLTPKEYELLYFLAKTPDK
HHHCCCCCEEEECCCCCCEEEEEEECCCCCCCEEECCCCEEEECCCCEEEEEEEECCCHH
VYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPGAAKKIVTVWGVGYKFEVGAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]