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The map label for this gene is mecB [H]

Identifier: 154686543

GI number: 154686543

Start: 2208811

End: 2209395

Strand: Reverse

Name: mecB [H]

Synonym: RBAM_021120

Alternate gene names: 154686543

Gene position: 2209395-2208811 (Counterclockwise)

Preceding gene: 154686544

Following gene: 154686542

Centisome position: 56.38

GC content: 46.5

Gene sequence:

>585_bases
ATGCGGCTTGAGCGTCTGAACTATAATAAGATTAAAATCTTTTTAACCCTCGACGATCTGACTGATCGGGGACTGACAAA
AGAAGACCTCTGGAAGGACTCGTTTAAAGTCCACCAGTTATTTAAAGATATGATGAATGAAGCAAATACAGAGCTCGGCT
TTGAAGCGAATGGTCCGATCGCGGTGGAAGTATATTCTCTTCAGGCACAAGGCATGGTTGTGATTGTAACGAAAAATCAT
GACGCGGACGCAGAAGATGACGAATATGACGATGATTACATCGAGATGCAGGTCAAACTTGACGAAAGCCCGGATATTAT
TTATCAGTTCCATTCGTTTGAAGATATCATTCAGCTTGCCGGAAGCCTTCACCGAATCGGGATTACCGGCGGCACCGTCT
ACCACTATGAGAACCAATACTATGTAAGCCTTGAAGACCTCGGCTCCCGGTCCGCCGAAGGCGTCATCGCGGTGCTGGCT
GAATACGGACACCCGGCGACGATTACGATTTACAGGCTCCATGAGTACGGAAAACTCATCATGGACGGCAATGCTGTGGA
GACCATCCACAAACATTTTTCATAA

Upstream 100 bases:

>100_bases
GTACACGGTGTAAACTGATAACAAATTAAGAACCTATGACTCATTTATTCATATACTGTGTTATATGATTTGTGTGCAAG
AAGAGGCAGGAGGGAACATT

Downstream 100 bases:

>100_bases
AAAAGATTTGAAACGGCAGCTGTTTTCAGCGGCCGTCTTTTTTTAGGCGAAATAATGGAAAAATCATTGTCTTTCTTCTA
TGCACGGAGATATTGAAGGT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MRLERLNYNKIKIFLTLDDLTDRGLTKEDLWKDSFKVHQLFKDMMNEANTELGFEANGPIAVEVYSLQAQGMVVIVTKNH
DADAEDDEYDDDYIEMQVKLDESPDIIYQFHSFEDIIQLAGSLHRIGITGGTVYHYENQYYVSLEDLGSRSAEGVIAVLA
EYGHPATITIYRLHEYGKLIMDGNAVETIHKHFS

Sequences:

>Translated_194_residues
MRLERLNYNKIKIFLTLDDLTDRGLTKEDLWKDSFKVHQLFKDMMNEANTELGFEANGPIAVEVYSLQAQGMVVIVTKNH
DADAEDDEYDDDYIEMQVKLDESPDIIYQFHSFEDIIQLAGSLHRIGITGGTVYHYENQYYVSLEDLGSRSAEGVIAVLA
EYGHPATITIYRLHEYGKLIMDGNAVETIHKHFS
>Mature_194_residues
MRLERLNYNKIKIFLTLDDLTDRGLTKEDLWKDSFKVHQLFKDMMNEANTELGFEANGPIAVEVYSLQAQGMVVIVTKNH
DADAEDDEYDDDYIEMQVKLDESPDIIYQFHSFEDIIQLAGSLHRIGITGGTVYHYENQYYVSLEDLGSRSAEGVIAVLA
EYGHPATITIYRLHEYGKLIMDGNAVETIHKHFS

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved in Spx degradation by ClpC. Acts negatively in the development of competence by binding ComK and rec

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 22227; Mature: 22227

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLERLNYNKIKIFLTLDDLTDRGLTKEDLWKDSFKVHQLFKDMMNEANTELGFEANGPI
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCE
AVEVYSLQAQGMVVIVTKNHDADAEDDEYDDDYIEMQVKLDESPDIIYQFHSFEDIIQLA
EEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCHHHHHHHH
GSLHRIGITGGTVYHYENQYYVSLEDLGSRSAEGVIAVLAEYGHPATITIYRLHEYGKLI
CCEEEEEECCCEEEEECCEEEEEHHHCCCCCCCCCEEEEECCCCCEEEEEEEEECCCEEE
MDGNAVETIHKHFS
ECCCHHHHHHHHCC
>Mature Secondary Structure
MRLERLNYNKIKIFLTLDDLTDRGLTKEDLWKDSFKVHQLFKDMMNEANTELGFEANGPI
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCE
AVEVYSLQAQGMVVIVTKNHDADAEDDEYDDDYIEMQVKLDESPDIIYQFHSFEDIIQLA
EEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCHHHHHHHH
GSLHRIGITGGTVYHYENQYYVSLEDLGSRSAEGVIAVLAEYGHPATITIYRLHEYGKLI
CCEEEEEECCCEEEEECCEEEEEHHHCCCCCCCCCEEEEECCCCCEEEEEEEEECCCEEE
MDGNAVETIHKHFS
ECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]