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The map label for this gene is hepT [H]

Identifier: 154686522

GI number: 154686522

Start: 2188385

End: 2189434

Strand: Reverse

Name: hepT [H]

Synonym: RBAM_020900

Alternate gene names: 154686522

Gene position: 2189434-2188385 (Counterclockwise)

Preceding gene: 154686523

Following gene: 154686521

Centisome position: 55.87

GC content: 46.86

Gene sequence:

>1050_bases
ATGTCAAATACCATTCGTTTACCGGCGGAGTGGCCGCTACGCATATCGGTTGGAAATGATGAATATACAGATGTTTGGGT
GAATGATATGAAATTTAAAATGGCCTATTCTTTTTTAAATGACGATATTGATGTGATCGAAAGGGAGCTTGAGCAAACGG
TGCGGTCAGACTATCCTTTGCTGAGTGAAGCCGGGCTCCATCTGCTCCAGGCGGGCGGCAAGCGGATCCGCCCTGTTTTC
GTATTGCTTTCCGGCATGTTCGGCGACTATGACATTAATAAAATAAAATATGTTGCGGTGACGCTGGAAATGATTCATAT
GGCGTCCCTCGTGCATGACGACGTCATTGATGACGCCGAGCTGCGGAGGGGAAAACCGACCATCAAAGCCAAGTGGGACA
ACCGCATCGCCATGTATACCGGTGATTATATGCTTGCGGGCTCACTTGAGATGATGACGAGATTGGATGAGCCGAAAGCC
CACCGGATCCTGTCCAAAACCATCGTAGAAGTATGCCTCGGAGAAATTGAACAGATCAGAGATAAATACAATATGGAACA
AAACCTCAGAACCTATTTGCGCCGCATCAAACGGAAAACGGCTCTTCTCATTGCCGTCAGCTGCCAGCTCGGCGCCATCG
CTTCGGGAGCTGATGAGAAGATTCACAAAGCATTATATTGGTTCGGTTATTACGTGGGCATGTCCTATCAGATTATTGAC
GACATTCTTGATTTCACTTCAACGGAAGAGGAACTGGGAAAACCGGTCGGAGGGGATCTGCTGCAAGGAAATGTCACTCT
GCCCGTTTTGTACGCGCTCCGTCAGCCTGAATTGAAAAATCAGCTGAAATTAATTAACAGTGAAACAACACAGGAGCAGC
TCGCCCCCATTATTGAAAATATTAAACGCACAGACGCGATTGAAAAATCAATGGCCGTCAGTGACAGGTACTTAAAAAAA
GCGTTTGAAAAACTGAATACACTGCCGAGAGGACGTGCGCGCTCATCATTGGCCGCCATCGCCAAATATATCGGCAAACG
GAAATTTTAA

Upstream 100 bases:

>100_bases
GCGAAGAGCTATAAAGAATATTCTTGGCTTCAAGAATCGGCAAGAGAATTTCCCGGTATGAAAGAGCTTGCGCGTCTGTT
TGAAGAAGCGGGCCTGACGA

Downstream 100 bases:

>100_bases
ATTCCTTTTTACGAACAAGATGTGAACATTCTCCGCCCTGGATTGATTAATTGTCAGAAAGATGTTACGATTTCGGTGTG
CAACTTGAAAGCCTATACAT

Product: heptaprenyl diphosphate synthase subunit HepT

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSNTIRLPAEWPLRISVGNDEYTDVWVNDMKFKMAYSFLNDDIDVIERELEQTVRSDYPLLSEAGLHLLQAGGKRIRPVF
VLLSGMFGDYDINKIKYVAVTLEMIHMASLVHDDVIDDAELRRGKPTIKAKWDNRIAMYTGDYMLAGSLEMMTRLDEPKA
HRILSKTIVEVCLGEIEQIRDKYNMEQNLRTYLRRIKRKTALLIAVSCQLGAIASGADEKIHKALYWFGYYVGMSYQIID
DILDFTSTEEELGKPVGGDLLQGNVTLPVLYALRQPELKNQLKLINSETTQEQLAPIIENIKRTDAIEKSMAVSDRYLKK
AFEKLNTLPRGRARSSLAAIAKYIGKRKF

Sequences:

>Translated_349_residues
MSNTIRLPAEWPLRISVGNDEYTDVWVNDMKFKMAYSFLNDDIDVIERELEQTVRSDYPLLSEAGLHLLQAGGKRIRPVF
VLLSGMFGDYDINKIKYVAVTLEMIHMASLVHDDVIDDAELRRGKPTIKAKWDNRIAMYTGDYMLAGSLEMMTRLDEPKA
HRILSKTIVEVCLGEIEQIRDKYNMEQNLRTYLRRIKRKTALLIAVSCQLGAIASGADEKIHKALYWFGYYVGMSYQIID
DILDFTSTEEELGKPVGGDLLQGNVTLPVLYALRQPELKNQLKLINSETTQEQLAPIIENIKRTDAIEKSMAVSDRYLKK
AFEKLNTLPRGRARSSLAAIAKYIGKRKF
>Mature_348_residues
SNTIRLPAEWPLRISVGNDEYTDVWVNDMKFKMAYSFLNDDIDVIERELEQTVRSDYPLLSEAGLHLLQAGGKRIRPVFV
LLSGMFGDYDINKIKYVAVTLEMIHMASLVHDDVIDDAELRRGKPTIKAKWDNRIAMYTGDYMLAGSLEMMTRLDEPKAH
RILSKTIVEVCLGEIEQIRDKYNMEQNLRTYLRRIKRKTALLIAVSCQLGAIASGADEKIHKALYWFGYYVGMSYQIIDD
ILDFTSTEEELGKPVGGDLLQGNVTLPVLYALRQPELKNQLKLINSETTQEQLAPIIENIKRTDAIEKSMAVSDRYLKKA
FEKLNTLPRGRARSSLAAIAKYIGKRKF

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=337, Percent_Identity=29.9703264094956, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI4758430, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI83700220, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI169808399, Length=359, Percent_Identity=23.6768802228412, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1789578, Length=301, Percent_Identity=32.2259136212625, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786623, Length=240, Percent_Identity=31.25, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17505681, Length=315, Percent_Identity=33.3333333333333, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6319475, Length=301, Percent_Identity=30.2325581395349, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6325188, Length=230, Percent_Identity=24.7826086956522, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24651612, Length=323, Percent_Identity=29.1021671826625, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI281365769, Length=277, Percent_Identity=25.2707581227437, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24660002, Length=277, Percent_Identity=25.2707581227437, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 39863; Mature: 39732

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTIRLPAEWPLRISVGNDEYTDVWVNDMKFKMAYSFLNDDIDVIERELEQTVRSDYPL
CCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
LSEAGLHLLQAGGKRIRPVFVLLSGMFGDYDINKIKYVAVTLEMIHMASLVHDDVIDDAE
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHH
LRRGKPTIKAKWDNRIAMYTGDYMLAGSLEMMTRLDEPKAHRILSKTIVEVCLGEIEQIR
HHCCCCCEEEECCCEEEEEECCEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKYNMEQNLRTYLRRIKRKTALLIAVSCQLGAIASGADEKIHKALYWFGYYVGMSYQIID
HHHCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
DILDFTSTEEELGKPVGGDLLQGNVTLPVLYALRQPELKNQLKLINSETTQEQLAPIIEN
HHHHCCCCHHHHCCCCCCCEEECCCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
IKRTDAIEKSMAVSDRYLKKAFEKLNTLPRGRARSSLAAIAKYIGKRKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNTIRLPAEWPLRISVGNDEYTDVWVNDMKFKMAYSFLNDDIDVIERELEQTVRSDYPL
CCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
LSEAGLHLLQAGGKRIRPVFVLLSGMFGDYDINKIKYVAVTLEMIHMASLVHDDVIDDAE
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHH
LRRGKPTIKAKWDNRIAMYTGDYMLAGSLEMMTRLDEPKAHRILSKTIVEVCLGEIEQIR
HHCCCCCEEEECCCEEEEEECCEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKYNMEQNLRTYLRRIKRKTALLIAVSCQLGAIASGADEKIHKALYWFGYYVGMSYQIID
HHHCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
DILDFTSTEEELGKPVGGDLLQGNVTLPVLYALRQPELKNQLKLINSETTQEQLAPIIEN
HHHHCCCCHHHHCCCCCCCEEECCCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
IKRTDAIEKSMAVSDRYLKKAFEKLNTLPRGRARSSLAAIAKYIGKRKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]