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The map label for this gene is xpt

Identifier: 154686458

GI number: 154686458

Start: 2129393

End: 2129977

Strand: Reverse

Name: xpt

Synonym: RBAM_020260

Alternate gene names: 154686458

Gene position: 2129977-2129393 (Counterclockwise)

Preceding gene: 154686459

Following gene: 154686457

Centisome position: 54.36

GC content: 46.5

Gene sequence:

>585_bases
GTGGAAGCGTTAAAACGAAAAATAGCAGAAGACGGAATCGTTCTTTCTGATCAAGTGCTGAAAGTGGATTCTTTTTTAAA
CCATCAAATTGATCCGGTTCTCATGCAGCAGATCGGCCGGGAATTTGCGCGCCGTTTTGAAAAAGACGAGATAACCAAAA
TCGTCACAATTGAATCTTCCGGCATTGCCCCTGCGGTGATGGCCGGCCTTGAACTCGGCGTTCCCGTCATCTTTGCGAGA
AAAAGGAAGTCTCTCACATTAACGGATGATCTGCTGACGGCATCCGTCTATTCTTTCACGAAAAAAACAGAAAGTCAGAT
TGCAATCTCCGGAAATCATCTGTCGAAAGATGACCGCGTGTTAATCATTGACGACTTTTTAGCGAACGGACAGGCGGCAG
AAGGACTTTTATCCATCGTAAAACAAGCAGGTGCAGCGGTTTGCGGGATCGGAATCGTCATTGAAAAGTCATTTCAGCCG
GGAAGAGATGAGCTGGTGAAAAAAGGATGCCGGGTCGAATCACTGGCGAGAATCCAATCGCTTGAAGACGGAAAAGTGAC
ATTTGTACAGGAGGTCCGTTCATGA

Upstream 100 bases:

>100_bases
CTTTATTCGGCCGTTACGTGTAGATCATTCGGCATTGCTTGCTCTTTTTTTGGAGAGCGGGCGATGCTTTTTTTATTTTT
TATAAGCGGGGGTAATCATT

Downstream 100 bases:

>100_bases
AAAACGGCTATGCCAAAACACTTTCCCTCGGTATCCAGCACGTGCTTGCCATGTATGCCGGCGCCGTCGTCGTTCCCTTA
ATTGTAGGAGCGGCATTGGG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MEALKRKIAEDGIVLSDQVLKVDSFLNHQIDPVLMQQIGREFARRFEKDEITKIVTIESSGIAPAVMAGLELGVPVIFAR
KRKSLTLTDDLLTASVYSFTKKTESQIAISGNHLSKDDRVLIIDDFLANGQAAEGLLSIVKQAGAAVCGIGIVIEKSFQP
GRDELVKKGCRVESLARIQSLEDGKVTFVQEVRS

Sequences:

>Translated_194_residues
MEALKRKIAEDGIVLSDQVLKVDSFLNHQIDPVLMQQIGREFARRFEKDEITKIVTIESSGIAPAVMAGLELGVPVIFAR
KRKSLTLTDDLLTASVYSFTKKTESQIAISGNHLSKDDRVLIIDDFLANGQAAEGLLSIVKQAGAAVCGIGIVIEKSFQP
GRDELVKKGCRVESLARIQSLEDGKVTFVQEVRS
>Mature_194_residues
MEALKRKIAEDGIVLSDQVLKVDSFLNHQIDPVLMQQIGREFARRFEKDEITKIVTIESSGIAPAVMAGLELGVPVIFAR
KRKSLTLTDDLLTASVYSFTKKTESQIAISGNHLSKDDRVLIIDDFLANGQAAEGLLSIVKQAGAAVCGIGIVIEKSFQP
GRDELVKKGCRVESLARIQSLEDGKVTFVQEVRS

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_BACA2 (A7Z5W2)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421619.1
- ProteinModelPortal:   A7Z5W2
- SMR:   A7Z5W2
- STRING:   A7Z5W2
- EnsemblBacteria:   EBBACT00000005728
- GeneID:   5459853
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020260
- eggNOG:   COG0503
- GeneTree:   EBGT00050000001498
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   BAMY326423:RBAM_020260-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21212; Mature: 21212

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALKRKIAEDGIVLSDQVLKVDSFLNHQIDPVLMQQIGREFARRFEKDEITKIVTIESS
CHHHHHHHHHCCEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCEEEEEEECC
GIAPAVMAGLELGVPVIFARKRKSLTLTDDLLTASVYSFTKKTESQIAISGNHLSKDDRV
CCCHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCE
LIIDDFLANGQAAEGLLSIVKQAGAAVCGIGIVIEKSFQPGRDELVKKGCRVESLARIQS
EEEECCCCCCHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCHHHHHHCCCCHHHHHHHHC
LEDGKVTFVQEVRS
CCCCCHHHHHHHCC
>Mature Secondary Structure
MEALKRKIAEDGIVLSDQVLKVDSFLNHQIDPVLMQQIGREFARRFEKDEITKIVTIESS
CHHHHHHHHHCCEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHCEEEEEEECC
GIAPAVMAGLELGVPVIFARKRKSLTLTDDLLTASVYSFTKKTESQIAISGNHLSKDDRV
CCCHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCE
LIIDDFLANGQAAEGLLSIVKQAGAAVCGIGIVIEKSFQPGRDELVKKGCRVESLARIQS
EEEECCCCCCHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCHHHHHHCCCCHHHHHHHHC
LEDGKVTFVQEVRS
CCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA