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The map label for this gene is yodQ [H]

Identifier: 154686386

GI number: 154686386

Start: 2067438

End: 2068739

Strand: Reverse

Name: yodQ [H]

Synonym: RBAM_019540

Alternate gene names: 154686386

Gene position: 2068739-2067438 (Counterclockwise)

Preceding gene: 154686387

Following gene: 154686385

Centisome position: 52.79

GC content: 52.15

Gene sequence:

>1302_bases
ATGGATCAATTAGAAGAGAAAGTCACTGAGTGGGCGGAAGAAAACACAGCAAAAGCGGTAAGCTTGCTGAAACGGCTGAT
CGGGGAAAAAAGCACGTTCGGCCATGAATTTAACGCACAGGCAGTCGTTTTAGAAAAACTGAGACAGTTTGACATGGATA
TTGATGTATGGGAGCCGAGTGTCAAACATTTGAAAGAGCATCCTTATTTCGTATCTGAACGCGAAGACTTCCATGAAAGC
CCGAATATCACAGCCGTAAAGAAAGGGGCCGGGGGCGGAAGATCACTGATACTGAACGGACATATTGATGTTGTCCCGGA
AGGAAATCCCGCCGCATGGACGTATGAACCGTTTACCGCTGTTGAAAAGGACGGCAAAGTTTACGGCCGCGGGTCAACGG
ATATGAAAGGCGGCAATACAGCCCTCTTGTTTGCGTTAGAAGCGCTTGAAGCCTGCGGGATTACGTTAAAAGGAGATGTC
CTGTTTCAAAGTGTCGTAGATGAAGAGTGCGGCGGCGCGGGAACGCTGTCGGCTGTTATGAGGGGCTACAAGGCTGACGG
GGCGCTTATTCCCGAACCGACTAATCTAAAGCTGTTTGTTAAGCAGCAAGGCTCTATGTGGTTCCGCATTACGGTAAGGG
GATTGTCCGCACACGGCGGCACCCGCTATGAAGGGGTGAGCGCCATTGAAAAAAGCCTGCATGTCATCACAGCCCTTAAA
GAGCTTGAACACGTCCGCAACGCCCGTATCACAGACCCGCTTTATCGGGACGTTCCGATCCCGGTTCCCATTAATATCGG
CACCGTCCAAGGGGGAACGTGGCCATCATCGGTAGCTGACCGTGTGGTGATAGAAGGCAGGTGCGGAATAGCTCCGGATG
AAACGCCCGAAGCAGTAAAAGAAGAGCTCGCAAGCTGGCTGAAAGATTTGGAGTACCGGGATGAGTGGTTTAAACACCAC
CCGGCGGAAATAGAATGGTTTGGCGCTCAGTGGCTTCCGAATGATCTCCCGGATGAGCATCCGCTGATTTCCGCTCTGGA
ATCTTCTTTTGAGAAAATGAAAGGGGCAAAACCGGTTCGTGAAGCGTCCCCGTGGGGAACGGACGGAGGGCTTTTGCAGC
ACGCGGGACAGACGCCGGTCATCGTCTTCGGGCCGGGAGAAGTCAAGGCGGCGCATCAGGCGAATGAATACATTGAAATC
CGGGCGTTAATCGATGCCGTCAAAATCATTTCTCTTTTTATCATGGAATGGTGCGGGGTGGCAGATGGGGGTGACGGAGC
TGATAAAGGAACTGAGGGCTGA

Upstream 100 bases:

>100_bases
CTTGAGGAACTGCTGAATGGCACGACCATAGACGATGTCATTCAAACAACGGATGCCGAAATCAGATTGGGAGAATGTTT
TCTTAAAAGGGGGTCTGTCC

Downstream 100 bases:

>100_bases
AAAGGGAGCGGCCGAGATTGATGCAGACCGTTTCAATGAGCGGCTCAGAGTCATTCGTTATGACGGACAGATCACGGCGC
TTATTCCGGCCGTTTTGGCA

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MDQLEEKVTEWAEENTAKAVSLLKRLIGEKSTFGHEFNAQAVVLEKLRQFDMDIDVWEPSVKHLKEHPYFVSEREDFHES
PNITAVKKGAGGGRSLILNGHIDVVPEGNPAAWTYEPFTAVEKDGKVYGRGSTDMKGGNTALLFALEALEACGITLKGDV
LFQSVVDEECGGAGTLSAVMRGYKADGALIPEPTNLKLFVKQQGSMWFRITVRGLSAHGGTRYEGVSAIEKSLHVITALK
ELEHVRNARITDPLYRDVPIPVPINIGTVQGGTWPSSVADRVVIEGRCGIAPDETPEAVKEELASWLKDLEYRDEWFKHH
PAEIEWFGAQWLPNDLPDEHPLISALESSFEKMKGAKPVREASPWGTDGGLLQHAGQTPVIVFGPGEVKAAHQANEYIEI
RALIDAVKIISLFIMEWCGVADGGDGADKGTEG

Sequences:

>Translated_433_residues
MDQLEEKVTEWAEENTAKAVSLLKRLIGEKSTFGHEFNAQAVVLEKLRQFDMDIDVWEPSVKHLKEHPYFVSEREDFHES
PNITAVKKGAGGGRSLILNGHIDVVPEGNPAAWTYEPFTAVEKDGKVYGRGSTDMKGGNTALLFALEALEACGITLKGDV
LFQSVVDEECGGAGTLSAVMRGYKADGALIPEPTNLKLFVKQQGSMWFRITVRGLSAHGGTRYEGVSAIEKSLHVITALK
ELEHVRNARITDPLYRDVPIPVPINIGTVQGGTWPSSVADRVVIEGRCGIAPDETPEAVKEELASWLKDLEYRDEWFKHH
PAEIEWFGAQWLPNDLPDEHPLISALESSFEKMKGAKPVREASPWGTDGGLLQHAGQTPVIVFGPGEVKAAHQANEYIEI
RALIDAVKIISLFIMEWCGVADGGDGADKGTEG
>Mature_433_residues
MDQLEEKVTEWAEENTAKAVSLLKRLIGEKSTFGHEFNAQAVVLEKLRQFDMDIDVWEPSVKHLKEHPYFVSEREDFHES
PNITAVKKGAGGGRSLILNGHIDVVPEGNPAAWTYEPFTAVEKDGKVYGRGSTDMKGGNTALLFALEALEACGITLKGDV
LFQSVVDEECGGAGTLSAVMRGYKADGALIPEPTNLKLFVKQQGSMWFRITVRGLSAHGGTRYEGVSAIEKSLHVITALK
ELEHVRNARITDPLYRDVPIPVPINIGTVQGGTWPSSVADRVVIEGRCGIAPDETPEAVKEELASWLKDLEYRDEWFKHH
PAEIEWFGAQWLPNDLPDEHPLISALESSFEKMKGAKPVREASPWGTDGGLLQHAGQTPVIVFGPGEVKAAHQANEYIEI
RALIDAVKIISLFIMEWCGVADGGDGADKGTEG

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=310, Percent_Identity=25.4838709677419, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790395, Length=343, Percent_Identity=30.6122448979592, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789236, Length=340, Percent_Identity=24.1176470588235, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788816, Length=397, Percent_Identity=23.6775818639798, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538640, Length=343, Percent_Identity=23.0320699708455, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356353, Length=345, Percent_Identity=24.0579710144928, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24649210, Length=340, Percent_Identity=23.2352941176471, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24649206, Length=227, Percent_Identity=25.9911894273128, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649202, Length=340, Percent_Identity=23.2352941176471, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649204, Length=340, Percent_Identity=23.2352941176471, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649208, Length=333, Percent_Identity=22.8228228228228, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649212, Length=335, Percent_Identity=23.2835820895522, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 47416; Mature: 47416

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLEEKVTEWAEENTAKAVSLLKRLIGEKSTFGHEFNAQAVVLEKLRQFDMDIDVWEPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHH
VKHLKEHPYFVSEREDFHESPNITAVKKGAGGGRSLILNGHIDVVPEGNPAAWTYEPFTA
HHHHHHCCCEECCCHHHCCCCCEEEEECCCCCCCEEEEECCEEEEECCCCCEEEECCCHH
VEKDGKVYGRGSTDMKGGNTALLFALEALEACGITLKGDVLFQSVVDEECGGAGTLSAVM
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHH
RGYKADGALIPEPTNLKLFVKQQGSMWFRITVRGLSAHGGTRYEGVSAIEKSLHVITALK
CCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
ELEHVRNARITDPLYRDVPIPVPINIGTVQGGTWPSSVADRVVIEGRCGIAPDETPEAVK
HHHHHHCCCCCCCHHHCCCCCCCEEECCCCCCCCCHHHHCEEEEECCCCCCCCCCHHHHH
EELASWLKDLEYRDEWFKHHPAEIEWFGAQWLPNDLPDEHPLISALESSFEKMKGAKPVR
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
EASPWGTDGGLLQHAGQTPVIVFGPGEVKAAHQANEYIEIRALIDAVKIISLFIMEWCGV
HCCCCCCCCHHHHCCCCCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
ADGGDGADKGTEG
CCCCCCCCCCCCC
>Mature Secondary Structure
MDQLEEKVTEWAEENTAKAVSLLKRLIGEKSTFGHEFNAQAVVLEKLRQFDMDIDVWEPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHH
VKHLKEHPYFVSEREDFHESPNITAVKKGAGGGRSLILNGHIDVVPEGNPAAWTYEPFTA
HHHHHHCCCEECCCHHHCCCCCEEEEECCCCCCCEEEEECCEEEEECCCCCEEEECCCHH
VEKDGKVYGRGSTDMKGGNTALLFALEALEACGITLKGDVLFQSVVDEECGGAGTLSAVM
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHH
RGYKADGALIPEPTNLKLFVKQQGSMWFRITVRGLSAHGGTRYEGVSAIEKSLHVITALK
CCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
ELEHVRNARITDPLYRDVPIPVPINIGTVQGGTWPSSVADRVVIEGRCGIAPDETPEAVK
HHHHHHCCCCCCCHHHCCCCCCCEEECCCCCCCCCHHHHCEEEEECCCCCCCCCCHHHHH
EELASWLKDLEYRDEWFKHHPAEIEWFGAQWLPNDLPDEHPLISALESSFEKMKGAKPVR
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
EASPWGTDGGLLQHAGQTPVIVFGPGEVKAAHQANEYIEIRALIDAVKIISLFIMEWCGV
HCCCCCCCCHHHHCCCCCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
ADGGDGADKGTEG
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]