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The map label for this gene is kamA [H]

Identifier: 154686384

GI number: 154686384

Start: 2065185

End: 2066606

Strand: Reverse

Name: kamA [H]

Synonym: RBAM_019520

Alternate gene names: 154686384

Gene position: 2066606-2065185 (Counterclockwise)

Preceding gene: 154686385

Following gene: 154686383

Centisome position: 52.74

GC content: 47.82

Gene sequence:

>1422_bases
TTGACAAACAAATGGTTTCAGCCGAAGCGTCATTGGAAGGAGATTGAATTGTGGAAAGATGTGCCGGAAGACAAGTGGAA
TGATTGGCTGTGGCAGCTCACCCATACTGTAAGAACCGTCGATGACCTGAAAAAAGTCATTCATTTGACCGAAGAGGAAG
AAGAAGGCGTCAGGATGTCTGTAAAAACCATTCCCCTGAACATTACGCCTTATTATGCTTCTTTAATGGATCCCGATAAC
CCGAGATGTCCGATCCGCATGCAGTCCGTGCCGCTGTCAGAAGAAATGCACAAAACGAAATATGACCTTGAAGATCCGCT
GTTTGAAGATGAAGATTCACCGGTTCCCGGTCTTACGCACCGATATCCCGACCGCGTTCTTTTTCTGGTGACAAATCAAT
GCTCGATGTATTGCCGATATTGCACCAGAAGGCGTTTTTCCGGACAGATCGGAATGGGGGTGCCGAAAAAACAGCTCGAT
GCGGCAATCGCTTACATCCGGGAAACGCCGGAAATCCGTGACTGCCTGATTTCCGGCGGAGACGGGCTTTTAATCAACGA
TCAGATTCTGGAATATATTTTGAAAAACCTGCGTGACATTCCCCATCTTGAAATTATCCGGATCGGAACGAGAGCGCCCG
TTGTATTTCCGCAGCGGATAACGGATAACCTTTGTGAGATTTTGAAAAAATATCATCCGGTCTGGCTGAACACTCATTTT
AATACGAGCATCGAACTGACGGAAGAATCGGTTGCGGCGTGTGAAAAGCTCGTTAACGCAGGTGTTCCGGTCGGTAACCA
GGCCGTTATTTTAGCAGGCATTAACGATTCGGTGCCGATTATGAAAAAACTCATGCATGATTTAGTGAAAATCCGTGTGC
GTCCGTATTATATTTATCAATGTGATTTGTCAGAGGGAATCGGCCATTTCAGAGCGCCTGTGTCAAAAGGGCTGGAAATC
ATTGAAGGACTGAGGGGCCACACAACGGGCTTTGCCGTGCCGACCTTTGTCGTCGACGCCCCGGGCGGAGGCGGTAAAAT
CGCCCTGCAGCCGAACTACTTGCTCTCCCAAAGTCCGGAGAAAGTTGTGATCAGAAACTTCGAAGGGGTGATTACATCTT
ATCCCGAGCCGGAAAACTATATCCCGAATCAAGCCGACGACTATTTTGAATCTGTTTTTCCGGGAACGATGGCCAAACGC
GAGCCGGTCGGACTGAGCGCCATTTTCGCGGACAAAGAGGTTTCGTTCACACCGGAAAATGTATCGAGGATCGACAGGAG
GAAAACGTTTACATCAAACCCTGATCATGAAACGCTGAAAGACCGCAGGGAAAAGAGAGATGAATTGAAAGAAAAGAAAT
TTATTGCACAGCAAAAGAAAGAGCAAAAAGCAGGATCGGAAGTCGGAGGTGAGTCGCCGTGA

Upstream 100 bases:

>100_bases
GAGGCAGGCTTGTGAACAACTGCCGCATTTCAGAAGGGCTCGAAAATATGAATATATGGTGCAAGACTTTACGTTTGGCC
ATTCATAAGGAGGAATTCGT

Downstream 100 bases:

>100_bases
AGCCATGCGAGTGGTGCGGCAATCAGAAGGCATCAGCTTGTCAGGCGGCTGTGTACTGGGAGCTTCCTGACGGTACGAGG
GCCATAGAAATTACAGAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MTNKWFQPKRHWKEIELWKDVPEDKWNDWLWQLTHTVRTVDDLKKVIHLTEEEEEGVRMSVKTIPLNITPYYASLMDPDN
PRCPIRMQSVPLSEEMHKTKYDLEDPLFEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
AAIAYIRETPEIRDCLISGGDGLLINDQILEYILKNLRDIPHLEIIRIGTRAPVVFPQRITDNLCEILKKYHPVWLNTHF
NTSIELTEESVAACEKLVNAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTTGFAVPTFVVDAPGGGGKIALQPNYLLSQSPEKVVIRNFEGVITSYPEPENYIPNQADDYFESVFPGTMAKR
EPVGLSAIFADKEVSFTPENVSRIDRRKTFTSNPDHETLKDRREKRDELKEKKFIAQQKKEQKAGSEVGGESP

Sequences:

>Translated_473_residues
MTNKWFQPKRHWKEIELWKDVPEDKWNDWLWQLTHTVRTVDDLKKVIHLTEEEEEGVRMSVKTIPLNITPYYASLMDPDN
PRCPIRMQSVPLSEEMHKTKYDLEDPLFEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
AAIAYIRETPEIRDCLISGGDGLLINDQILEYILKNLRDIPHLEIIRIGTRAPVVFPQRITDNLCEILKKYHPVWLNTHF
NTSIELTEESVAACEKLVNAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTTGFAVPTFVVDAPGGGGKIALQPNYLLSQSPEKVVIRNFEGVITSYPEPENYIPNQADDYFESVFPGTMAKR
EPVGLSAIFADKEVSFTPENVSRIDRRKTFTSNPDHETLKDRREKRDELKEKKFIAQQKKEQKAGSEVGGESP
>Mature_472_residues
TNKWFQPKRHWKEIELWKDVPEDKWNDWLWQLTHTVRTVDDLKKVIHLTEEEEEGVRMSVKTIPLNITPYYASLMDPDNP
RCPIRMQSVPLSEEMHKTKYDLEDPLFEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDA
AIAYIRETPEIRDCLISGGDGLLINDQILEYILKNLRDIPHLEIIRIGTRAPVVFPQRITDNLCEILKKYHPVWLNTHFN
TSIELTEESVAACEKLVNAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEII
EGLRGHTTGFAVPTFVVDAPGGGGKIALQPNYLLSQSPEKVVIRNFEGVITSYPEPENYIPNQADDYFESVFPGTMAKRE
PVGLSAIFADKEVSFTPENVSRIDRRKTFTSNPDHETLKDRREKRDELKEKKFIAQQKKEQKAGSEVGGESP

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=324, Percent_Identity=32.4074074074074, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR006638
- InterPro:   IPR022459 [H]

Pfam domain/function: NA

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 54134; Mature: 54002

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKWFQPKRHWKEIELWKDVPEDKWNDWLWQLTHTVRTVDDLKKVIHLTEEEEEGVRMS
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VKTIPLNITPYYASLMDPDNPRCPIRMQSVPLSEEMHKTKYDLEDPLFEDEDSPVPGLTH
EEEEEEEECHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDAAIAYIRETPEIRDCLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
DGLLINDQILEYILKNLRDIPHLEIIRIGTRAPVVFPQRITDNLCEILKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIELTEESVAACEKLVNAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQ
CCEEEECHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTTGFAVPTFVVDAPGGGGKIALQPNYLLSQSPE
ECHHHCHHHHHCCHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCEEEECCCHHHCCCCC
KVVIRNFEGVITSYPEPENYIPNQADDYFESVFPGTMAKREPVGLSAIFADKEVSFTPEN
CEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHH
VSRIDRRKTFTSNPDHETLKDRREKRDELKEKKFIAQQKKEQKAGSEVGGESP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TNKWFQPKRHWKEIELWKDVPEDKWNDWLWQLTHTVRTVDDLKKVIHLTEEEEEGVRMS
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VKTIPLNITPYYASLMDPDNPRCPIRMQSVPLSEEMHKTKYDLEDPLFEDEDSPVPGLTH
EEEEEEEECHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDAAIAYIRETPEIRDCLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
DGLLINDQILEYILKNLRDIPHLEIIRIGTRAPVVFPQRITDNLCEILKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIELTEESVAACEKLVNAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQ
CCEEEECHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTTGFAVPTFVVDAPGGGGKIALQPNYLLSQSPE
ECHHHCHHHHHCCHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCEEEECCCHHHCCCCC
KVVIRNFEGVITSYPEPENYIPNQADDYFESVFPGTMAKREPVGLSAIFADKEVSFTPEN
CEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHH
VSRIDRRKTFTSNPDHETLKDRREKRDELKEKKFIAQQKKEQKAGSEVGGESP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377; 10839984 [H]