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The map label for this gene is xylR [H]

Identifier: 154686167

GI number: 154686167

Start: 1800029

End: 1801183

Strand: Reverse

Name: xylR [H]

Synonym: RBAM_017340

Alternate gene names: 154686167

Gene position: 1801183-1800029 (Counterclockwise)

Preceding gene: 154686173

Following gene: 154686164

Centisome position: 45.97

GC content: 37.66

Gene sequence:

>1155_bases
GTGGATATCGCTGATCAAGCCTTTGTCAAAAAAGTTAACCAAAAGTTATTACTAAACGAAATACTTAAGAATTCTCCTAT
TTCAAGAGCAAAATTATCTGAAATGACCGGATTAAATAAATCAACTGTTTCGTCACAGGTAAACACATTAATGAAAGAAA
ACCTCGTATTTGAAATCGGTCAGGGACAATCAAGCGGCGGCAGAAGACCTGTTATGCTTGTTTTTAATAAAAAAGCAGGA
TACTCCGTAGGAATAGATGTTGGCGTGGATTATGTTAATGGCATTTTAACAGATCTTGAAGGAACGATCGTCCTTGATCA
ACACCACCATTTGGAATGCAATTCTCCAGAAATCACTAAAGATATTTTAATTGAGATGATTCATCATTTTATTGCAAAAA
TGCCGCAATCTCCATACGGTCTTATTGGTATAGGGATATGCGCGCCCGGGCTGATTGACAAAAATCAAAAAATTGTTTTC
GCTCCGAACGCCAACTGGAGAGATATTGACTTAAAATCTTTCATCCAAAAGAAGTTCAATGTGCCCGTTTTTATTGAAAA
TGAGGCAAATGCCGGCGCATATGGAGAAAAAGTATTTGGTGCTGCAAAAAATCACGATAACATTATTTATGCAAGTATCG
GTACAGGAATAGGGATCGGCGTTATGATCAACAATCATTTATATAGAGGGGTTGGCGGATTCTCTGGAGAAATGGGGCAT
ATGACAATAGACTTTAAGGGTCCTAAATGCAGCTGCGGAAACCGAGGCTGCTGGGAATTGTATGCTTCAGAGAAGGCTTT
AGTAACATCTCTTCAGACGAAAGAGAAAAAAGTGTCCAGCCAAGATATCATAGACCTTGCCCATCTGAATGATGTTGGAA
CTTTACAGGCATTACAGAATTTTGGTTTCTATTTAGGAATAGGCCTGACCAATATTTTAAATACATTTAATCCGCAAGCC
ATCATTTTAAGAAACAGCATCATTGAATCGCATCCTATGGTTTTACATTCAATTAAAAGTGAAGTGTCATCCAGGGTTTA
TTCCCAACTAGACAGTAGCTATGAATTATTACCATCTATCTTAGGAAAAAATGCACCCGCTCTAGGAATGTCCTCCATTG
TTATTGATCATTTTCTCGACATGGTTCATAACTGA

Upstream 100 bases:

>100_bases
ATTAGATATAATAAAGGTTGGATTTGCTATGTACTGCGTTTCGCACGATAACACAGAACGTTCAACTTAATTTAAAGATT
ATACAAATGGAGTGGATGAA

Downstream 100 bases:

>100_bases
AATGTACATACTTCTATGTTTTACGCTCATCTTTAAAGATGGGTTTTTTTATTCTAGGAATATTTCTGAACCAATACTGA
CATGGGCACCTTCTAATATG

Product: XylR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MDIADQAFVKKVNQKLLLNEILKNSPISRAKLSEMTGLNKSTVSSQVNTLMKENLVFEIGQGQSSGGRRPVMLVFNKKAG
YSVGIDVGVDYVNGILTDLEGTIVLDQHHHLECNSPEITKDILIEMIHHFIAKMPQSPYGLIGIGICAPGLIDKNQKIVF
APNANWRDIDLKSFIQKKFNVPVFIENEANAGAYGEKVFGAAKNHDNIIYASIGTGIGIGVMINNHLYRGVGGFSGEMGH
MTIDFKGPKCSCGNRGCWELYASEKALVTSLQTKEKKVSSQDIIDLAHLNDVGTLQALQNFGFYLGIGLTNILNTFNPQA
IILRNSIIESHPMVLHSIKSEVSSRVYSQLDSSYELLPSILGKNAPALGMSSIVIDHFLDMVHN

Sequences:

>Translated_384_residues
MDIADQAFVKKVNQKLLLNEILKNSPISRAKLSEMTGLNKSTVSSQVNTLMKENLVFEIGQGQSSGGRRPVMLVFNKKAG
YSVGIDVGVDYVNGILTDLEGTIVLDQHHHLECNSPEITKDILIEMIHHFIAKMPQSPYGLIGIGICAPGLIDKNQKIVF
APNANWRDIDLKSFIQKKFNVPVFIENEANAGAYGEKVFGAAKNHDNIIYASIGTGIGIGVMINNHLYRGVGGFSGEMGH
MTIDFKGPKCSCGNRGCWELYASEKALVTSLQTKEKKVSSQDIIDLAHLNDVGTLQALQNFGFYLGIGLTNILNTFNPQA
IILRNSIIESHPMVLHSIKSEVSSRVYSQLDSSYELLPSILGKNAPALGMSSIVIDHFLDMVHN
>Mature_384_residues
MDIADQAFVKKVNQKLLLNEILKNSPISRAKLSEMTGLNKSTVSSQVNTLMKENLVFEIGQGQSSGGRRPVMLVFNKKAG
YSVGIDVGVDYVNGILTDLEGTIVLDQHHHLECNSPEITKDILIEMIHHFIAKMPQSPYGLIGIGICAPGLIDKNQKIVF
APNANWRDIDLKSFIQKKFNVPVFIENEANAGAYGEKVFGAAKNHDNIIYASIGTGIGIGVMINNHLYRGVGGFSGEMGH
MTIDFKGPKCSCGNRGCWELYASEKALVTSLQTKEKKVSSQDIIDLAHLNDVGTLQALQNFGFYLGIGLTNILNTFNPQA
IILRNSIIESHPMVLHSIKSEVSSRVYSQLDSSYELLPSILGKNAPALGMSSIVIDHFLDMVHN

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=315, Percent_Identity=26.3492063492064, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4885285, Length=315, Percent_Identity=26.3492063492064, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI190014632, Length=315, Percent_Identity=26.3492063492064, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI298566315, Length=315, Percent_Identity=26.3492063492064, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI298566312, Length=170, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786891, Length=378, Percent_Identity=25.6613756613757, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787878, Length=358, Percent_Identity=24.0223463687151, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1790522, Length=260, Percent_Identity=24.6153846153846, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081733, Length=258, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787363, Length=281, Percent_Identity=21.7081850533808, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082127, Length=176, Percent_Identity=28.4090909090909, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42028; Mature: 42028

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIADQAFVKKVNQKLLLNEILKNSPISRAKLSEMTGLNKSTVSSQVNTLMKENLVFEIG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEC
QGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYVNGILTDLEGTIVLDQHHHLECNSPEITK
CCCCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHH
DILIEMIHHFIAKMPQSPYGLIGIGICAPGLIDKNQKIVFAPNANWRDIDLKSFIQKKFN
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCC
VPVFIENEANAGAYGEKVFGAAKNHDNIIYASIGTGIGIGVMINNHLYRGVGGFSGEMGH
CCEEEECCCCCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEEECCCEECCCCCCCCCCCE
MTIDFKGPKCSCGNRGCWELYASEKALVTSLQTKEKKVSSQDIIDLAHLNDVGTLQALQN
EEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
FGFYLGIGLTNILNTFNPQAIILRNSIIESHPMVLHSIKSEVSSRVYSQLDSSYELLPSI
CCEEEEHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LGKNAPALGMSSIVIDHFLDMVHN
HCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIADQAFVKKVNQKLLLNEILKNSPISRAKLSEMTGLNKSTVSSQVNTLMKENLVFEIG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEC
QGQSSGGRRPVMLVFNKKAGYSVGIDVGVDYVNGILTDLEGTIVLDQHHHLECNSPEITK
CCCCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHH
DILIEMIHHFIAKMPQSPYGLIGIGICAPGLIDKNQKIVFAPNANWRDIDLKSFIQKKFN
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCC
VPVFIENEANAGAYGEKVFGAAKNHDNIIYASIGTGIGIGVMINNHLYRGVGGFSGEMGH
CCEEEECCCCCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEEECCCEECCCCCCCCCCCE
MTIDFKGPKCSCGNRGCWELYASEKALVTSLQTKEKKVSSQDIIDLAHLNDVGTLQALQN
EEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
FGFYLGIGLTNILNTFNPQAIILRNSIIESHPMVLHSIKSEVSSRVYSQLDSSYELLPSI
CCEEEEHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LGKNAPALGMSSIVIDHFLDMVHN
HCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]