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The map label for this gene is galE1 [H]

Identifier: 154685647

GI number: 154685647

Start: 1182758

End: 1183750

Strand: Reverse

Name: galE1 [H]

Synonym: RBAM_012140

Alternate gene names: 154685647

Gene position: 1183750-1182758 (Counterclockwise)

Preceding gene: 154685648

Following gene: 154685646

Centisome position: 30.21

GC content: 47.94

Gene sequence:

>993_bases
ATGGCGATTCTCGTTCTCGGCGGAGCCGGCTATATCGGTTCTCATGCGGTTGATCAATTATTAAACAAAGGATTTAAAAC
GATAGCTGTGGATCATCTGCAGACAGGCCACCGGAAAGCTGTTCATGAAAAAGCAGTTTTTTACCATGGAGATATCCGTG
ACAAACCGTTTCTTCGCTCTGTGTTTGCGAAGGAGAACGTAACAGGCGTTCTCCATTTTGCCGCTCAATCCCTTGTCGGC
GAATCAATGAAAGACCCTCTTTCATATTTCAATAATAATGTGTACGGTACGCAAATTACACTGGAGGTCATGCAGGAATT
CGGGGTGAAACACATTGTGTTTTCTTCATCCGCCGCTGTATACGGCGAACCTGAAAAAGTGCCCATCACAGAAGACATGC
CGGAAAAGCCGGAAAGCGCATACGGCGAATCAAAACTCATGGCAGAAAAAATGCTGAAGTGGTGTGAAACCGCCTGCGGC
ATAAAATATGTCTCGCTTCGGTATTTTAACGTTGCCGGCGCGAAAACGGACGGTTCCATCGGAGAAGATCATCATCCGGA
AACCCACCTTATCCCTATCCTTTTACAAACCGCGCTCGGTCAGCGCGAGGAGGTTTTGATATTCGGCACTGACTATGATA
CAAAAGACGGCACGTGCATCCGCGATTATGTCCATGTTTCCGATTTAATCGATGCCCATATTCTCGCTCTGGAATATTTG
CAAAACGGCGGAGACAGCGGCATTTTCAATTTAGGATCAAGCAGCGGGTTTTCCGTATCAGAAATGGCCGAAGCGGCCCG
GCAAGTGACCGAAAGAGACATAAAAGTAAGAGCGGCCGCAAGAAGACCCGGTGATCCAAGCACCCTCATCGCTTCCAGCG
ATAAAGCGCGGAACATTCTGGGCTGGAATCCGAAACAAACGGACATATCGGAAATCATTGCGTCAGCATGGAATTGGCAT
CGGCAACATCCAAACGGATACAAGGACAAATGA

Upstream 100 bases:

>100_bases
GGCCGTTTCATCTCACTACCGCAGCAGGACAGGTCTTGAAGCTTCTTTTTACATCGCGGATATAAGCGATGGCGCGGCTG
AATGGAGGGAAAAATAAATC

Downstream 100 bases:

>100_bases
AATGGAGGCGGCGGTCATTGAAGTTTTTGAATCAGTGGCAGGGTTTCTGAAAGAAAGCACTGTCTTAGGCGACATAAATG
AAACAGATGTGATTTACACA

Product: GalE1

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAILVLGGAGYIGSHAVDQLLNKGFKTIAVDHLQTGHRKAVHEKAVFYHGDIRDKPFLRSVFAKENVTGVLHFAAQSLVG
ESMKDPLSYFNNNVYGTQITLEVMQEFGVKHIVFSSSAAVYGEPEKVPITEDMPEKPESAYGESKLMAEKMLKWCETACG
IKYVSLRYFNVAGAKTDGSIGEDHHPETHLIPILLQTALGQREEVLIFGTDYDTKDGTCIRDYVHVSDLIDAHILALEYL
QNGGDSGIFNLGSSSGFSVSEMAEAARQVTERDIKVRAAARRPGDPSTLIASSDKARNILGWNPKQTDISEIIASAWNWH
RQHPNGYKDK

Sequences:

>Translated_330_residues
MAILVLGGAGYIGSHAVDQLLNKGFKTIAVDHLQTGHRKAVHEKAVFYHGDIRDKPFLRSVFAKENVTGVLHFAAQSLVG
ESMKDPLSYFNNNVYGTQITLEVMQEFGVKHIVFSSSAAVYGEPEKVPITEDMPEKPESAYGESKLMAEKMLKWCETACG
IKYVSLRYFNVAGAKTDGSIGEDHHPETHLIPILLQTALGQREEVLIFGTDYDTKDGTCIRDYVHVSDLIDAHILALEYL
QNGGDSGIFNLGSSSGFSVSEMAEAARQVTERDIKVRAAARRPGDPSTLIASSDKARNILGWNPKQTDISEIIASAWNWH
RQHPNGYKDK
>Mature_329_residues
AILVLGGAGYIGSHAVDQLLNKGFKTIAVDHLQTGHRKAVHEKAVFYHGDIRDKPFLRSVFAKENVTGVLHFAAQSLVGE
SMKDPLSYFNNNVYGTQITLEVMQEFGVKHIVFSSSAAVYGEPEKVPITEDMPEKPESAYGESKLMAEKMLKWCETACGI
KYVSLRYFNVAGAKTDGSIGEDHHPETHLIPILLQTALGQREEVLIFGTDYDTKDGTCIRDYVHVSDLIDAHILALEYLQ
NGGDSGIFNLGSSSGFSVSEMAEAARQVTERDIKVRAAARRPGDPSTLIASSDKARNILGWNPKQTDISEIIASAWNWHR
QHPNGYKDK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=38.7096774193548, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=38.7096774193548, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=38.7096774193548, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI7657641, Length=346, Percent_Identity=26.878612716763, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI42516563, Length=312, Percent_Identity=25.9615384615385, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI193211614, Length=247, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI8393516, Length=247, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=39.0029325513196, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788353, Length=346, Percent_Identity=27.4566473988439, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI48994969, Length=344, Percent_Identity=27.906976744186, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=30.7116104868914, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=353, Percent_Identity=36.5439093484419, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71982038, Length=355, Percent_Identity=36.3380281690141, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17539532, Length=281, Percent_Identity=26.6903914590747, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=26.4615384615385, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=38.953488372093, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI19923002, Length=346, Percent_Identity=39.8843930635838, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=25.7142857142857, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36409; Mature: 36277

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLGGAGYIGSHAVDQLLNKGFKTIAVDHLQTGHRKAVHEKAVFYHGDIRDKPFLRS
CEEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHEEEECCCCCCHHHHH
VFAKENVTGVLHFAAQSLVGESMKDPLSYFNNNVYGTQITLEVMQEFGVKHIVFSSSAAV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCEE
YGEPEKVPITEDMPEKPESAYGESKLMAEKMLKWCETACGIKYVSLRYFNVAGAKTDGSI
CCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCC
GEDHHPETHLIPILLQTALGQREEVLIFGTDYDTKDGTCIRDYVHVSDLIDAHILALEYL
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QNGGDSGIFNLGSSSGFSVSEMAEAARQVTERDIKVRAAARRPGDPSTLIASSDKARNIL
HCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCCC
GWNPKQTDISEIIASAWNWHRQHPNGYKDK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AILVLGGAGYIGSHAVDQLLNKGFKTIAVDHLQTGHRKAVHEKAVFYHGDIRDKPFLRS
EEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHEEEECCCCCCHHHHH
VFAKENVTGVLHFAAQSLVGESMKDPLSYFNNNVYGTQITLEVMQEFGVKHIVFSSSAAV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCEE
YGEPEKVPITEDMPEKPESAYGESKLMAEKMLKWCETACGIKYVSLRYFNVAGAKTDGSI
CCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCC
GEDHHPETHLIPILLQTALGQREEVLIFGTDYDTKDGTCIRDYVHVSDLIDAHILALEYL
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QNGGDSGIFNLGSSSGFSVSEMAEAARQVTERDIKVRAAARRPGDPSTLIASSDKARNIL
HCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCCC
GWNPKQTDISEIIASAWNWHRQHPNGYKDK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]