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The map label for this gene is yhaU [H]

Identifier: 154685443

GI number: 154685443

Start: 986792

End: 988006

Strand: Reverse

Name: yhaU [H]

Synonym: RBAM_010090

Alternate gene names: 154685443

Gene position: 988006-986792 (Counterclockwise)

Preceding gene: 154685444

Following gene: 154685439

Centisome position: 25.21

GC content: 50.86

Gene sequence:

>1215_bases
ATGGACCATCTCGTATTTGAAGTCGGTACGGCGTTAGTTCTTGTGGCTATTGCGAGTGTCATCGCCAATAAAATTAAATT
CTCGATCATCCCCTTCCTGATCATTTTAGGAATGCTCGTCGGGCCGCACGCGCCCCAAGCGGGCATCATTGACCTGACGT
TTATCGAAAGCCGGGAAGTGATTGAATTTTTCGGACGGATGGGCGTCCTGTTCCTCCTCTTTTACCTCGGGCTTGAATTC
TCGGTCGGAAAATTAGTCAAATCCGGACGTTCTATCGCCGCCGGCGGAACGATTTATATTCTGATTAATTTCAGTTTAGG
GCTGATCTACGGCTTTATCACAGGCTTTTCCTTTTTGGAAGTGCTTGTATTGGCGGGCGTCATCACGATATCATCAAGCG
CCATTGTCGCAAAGGTGCTTGTCGACTTAAAGCGCACGGCCAATCCGGAAACGGAGCTGATTCTCGGCATCATTATGTTT
GAGGATATCTTTCTGGCGGTTTACTTGTCCGTCGTTTCCGGGCTTGTTCTGGGAGACGCGACGTCTGTCGGAGGCGCGCT
GATGTCAATCGTGATCGCTTTCGGATATATGCTGCTGTTTTTCATTGCCGCTCGAAAATTGCCGCCTCTGCTGAACAAGC
TGCTTGATATCCGTTCAAACGAGGTATTTGCCATCGTCATTTTCGCCGCGCTCTTTTTCATTGCCGGCTTTTCCGAAACG
ATTCATGTCGCTGAAGCGATCGGCGCGCTCTTGCTCGGACTCGTGTTTTCGGAGACGGCCCATTCTGACAGGATTGAGCA
TCTTGTCGTGCCGTTCCGTGACTTTTTCGGGGCCATGTTTTTCTTCAGCTTCGGTCTCAGCATTGATCCGTTTTCACTCG
GAGATGCGGTATGGCTTGCCCTCGGCGCCGTTCTGCTGACGATTGCCGGAAACTTTATTGCCGGCATGATCGCCGGGCGC
CGGGCGGGGCTTTCTCATAAAGCATCGTCTAATATCGGGCTGACCATTGTGTCACGCGGCGAATTCTCCATTATCGTCGC
AAATCTCGGCATCGCCGGCGGCCTGTCCGCTTCACTTAAACCTTTCGCCGCCTTATATGTTTTGATACTGGCCATCTTCG
GCCCTTTGCTCACGAAAGAATCGAAGCGGATATATCTCCTGTTGAACAGCGTGTTCAAATGGAAGACGCCTGAAAAGAAG
CCGCAGAAATCATAA

Upstream 100 bases:

>100_bases
CTCCTTGAAGCAAACGATACACTCGTCCTCTCAGGTGAAAGAAAGCATTTGAAAAAGCTGATCCAAGACTTCCTCTCCAG
AGACGGAGTGTGATCTGTTT

Downstream 100 bases:

>100_bases
AAAAAACTGACCTCTTCATAAGGGGTCAGTTTTTTTGAGCAGGAAGAAATTGCTGAAAAGCCGTTTTTTTATTAATGGAG
AAATGCTCTTTCCCCAGAAT

Product: YhaU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIILGMLVGPHAPQAGIIDLTFIESREVIEFFGRMGVLFLLFYLGLEF
SVGKLVKSGRSIAAGGTIYILINFSLGLIYGFITGFSFLEVLVLAGVITISSSAIVAKVLVDLKRTANPETELILGIIMF
EDIFLAVYLSVVSGLVLGDATSVGGALMSIVIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFAIVIFAALFFIAGFSET
IHVAEAIGALLLGLVFSETAHSDRIEHLVVPFRDFFGAMFFFSFGLSIDPFSLGDAVWLALGAVLLTIAGNFIAGMIAGR
RAGLSHKASSNIGLTIVSRGEFSIIVANLGIAGGLSASLKPFAALYVLILAIFGPLLTKESKRIYLLLNSVFKWKTPEKK
PQKS

Sequences:

>Translated_404_residues
MDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIILGMLVGPHAPQAGIIDLTFIESREVIEFFGRMGVLFLLFYLGLEF
SVGKLVKSGRSIAAGGTIYILINFSLGLIYGFITGFSFLEVLVLAGVITISSSAIVAKVLVDLKRTANPETELILGIIMF
EDIFLAVYLSVVSGLVLGDATSVGGALMSIVIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFAIVIFAALFFIAGFSET
IHVAEAIGALLLGLVFSETAHSDRIEHLVVPFRDFFGAMFFFSFGLSIDPFSLGDAVWLALGAVLLTIAGNFIAGMIAGR
RAGLSHKASSNIGLTIVSRGEFSIIVANLGIAGGLSASLKPFAALYVLILAIFGPLLTKESKRIYLLLNSVFKWKTPEKK
PQKS
>Mature_404_residues
MDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIILGMLVGPHAPQAGIIDLTFIESREVIEFFGRMGVLFLLFYLGLEF
SVGKLVKSGRSIAAGGTIYILINFSLGLIYGFITGFSFLEVLVLAGVITISSSAIVAKVLVDLKRTANPETELILGIIMF
EDIFLAVYLSVVSGLVLGDATSVGGALMSIVIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFAIVIFAALFFIAGFSET
IHVAEAIGALLLGLVFSETAHSDRIEHLVVPFRDFFGAMFFFSFGLSIDPFSLGDAVWLALGAVLLTIAGNFIAGMIAGR
RAGLSHKASSNIGLTIVSRGEFSIIVANLGIAGGLSASLKPFAALYVLILAIFGPLLTKESKRIYLLLNSVFKWKTPEKK
PQKS

Specific function: Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of khtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=298, Percent_Identity=25.1677852348993, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1786685, Length=354, Percent_Identity=26.271186440678, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786232, Length=261, Percent_Identity=23.3716475095785, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 43348; Mature: 43348

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIILGMLVGPHAPQAGIIDLTFIESREV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHH
IEFFGRMGVLFLLFYLGLEFSVGKLVKSGRSIAAGGTIYILINFSLGLIYGFITGFSFLE
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCEEEEEEEHHHHHHHHHHHHHHHHH
VLVLAGVITISSSAIVAKVLVDLKRTANPETELILGIIMFEDIFLAVYLSVVSGLVLGDA
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSVGGALMSIVIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFAIVIFAALFFIAGFSET
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHH
IHVAEAIGALLLGLVFSETAHSDRIEHLVVPFRDFFGAMFFFSFGLSIDPFSLGDAVWLA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LGAVLLTIAGNFIAGMIAGRRAGLSHKASSNIGLTIVSRGEFSIIVANLGIAGGLSASLK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCHH
PFAALYVLILAIFGPLLTKESKRIYLLLNSVFKWKTPEKKPQKS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIILGMLVGPHAPQAGIIDLTFIESREV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHH
IEFFGRMGVLFLLFYLGLEFSVGKLVKSGRSIAAGGTIYILINFSLGLIYGFITGFSFLE
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCEEEEEEEHHHHHHHHHHHHHHHHH
VLVLAGVITISSSAIVAKVLVDLKRTANPETELILGIIMFEDIFLAVYLSVVSGLVLGDA
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSVGGALMSIVIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFAIVIFAALFFIAGFSET
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHH
IHVAEAIGALLLGLVFSETAHSDRIEHLVVPFRDFFGAMFFFSFGLSIDPFSLGDAVWLA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LGAVLLTIAGNFIAGMIAGRRAGLSHKASSNIGLTIVSRGEFSIIVANLGIAGGLSASLK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCHH
PFAALYVLILAIFGPLLTKESKRIYLLLNSVFKWKTPEKKPQKS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]