Click here to switch to the map view.

The map label for this gene is citR [H]

Identifier: 154685403

GI number: 154685403

Start: 948517

End: 949392

Strand: Reverse

Name: citR [H]

Synonym: RBAM_009690

Alternate gene names: 154685403

Gene position: 949392-948517 (Counterclockwise)

Preceding gene: 154685408

Following gene: 154685401

Centisome position: 24.23

GC content: 48.86

Gene sequence:

>876_bases
ATGGATTTTAAATGGCTTCACACCTTCGTCACCGCGGCAAAATATGAGAATTTCAGAAAAACGGCGGAAACGCTTTTTTT
ATCTCAGCCGACCGTCACCGTTCATATAAAATTATTAGAGAAAGAAATCAGCTGCAAGCTGTTTCAGCGAAGCGGCCGGA
AAATACAATTGACGGAAGAAGGAAAAGCATACGTGCCGTTTGCCATGAGGCTTTTGGAAGACTATGAAAACAGCATGGCG
GAACTGCACAGGGTGCGCCAGGGCTACTCGCACACGCTGACACTCGCTGTTTCGCCGCTTATCGCCGACACCGTTCTCCC
GTCTGTCATGAAGCGTTATACAGAGGACAATAAAGAAACCGAAATGACGGTCACCATTTTCGAATCGGAAGAAATCGCCT
CTCAAATCAGAAACGGCTCAGCCGATATCGGACTGAGCTGCTTAAAGGTGCAATCATCTTCCCTCACTTGCCGCCCCCTG
TACAATGACCCCGTTGTCCTCGTCGCGCCGCCCGGCCGAAAACCCGGAACAGGGAAGGCGGATGAAGTGAAAGACCTGTT
CGGACAATATCTGCTTTTGACCCATAACCATCCTGACTATTGGGATGATTTGCTCCGCCAGGTCAGAATACAGTTCCCTT
TCGTCAGGACAATGAAGGTGACACAGACGCATATTACGAAACGATTTATTAAAGAGGGGCTGGGTGTCTCATTTCTGCCG
CTGTCAGCAGTACGGGCCGAACTCGCCGCAGGCAGCATGATTGAAATTCCGTGCGAATTCGCCCAGATGCCGAGCGCGGG
CGCGTACGCCATCGCCCTCTATGAAAATGAAAAAAAGAAAACCTTTTTAGATTTTTTATCACATTTTCATTTTTAG

Upstream 100 bases:

>100_bases
CCCTTATCCTCTTTCTGTTATTATAGTAAATATAATATTTAAAAAATAATGAATATTTTTAAGGGAATTAATTAAAACTT
TTAATCAGAGGAGTGCATCT

Downstream 100 bases:

>100_bases
GTGAAACAAATGGAGCTCTGTCCCGTCTAAATAAAAAACCCGTTCTGATGAACGGGTTTCTATCGCTGCTAGAATCTTTT
CGCGCCAAGATAGCGAGGTT

Product: CitR

Products: NA

Alternate protein names: Citrate synthase I repressor [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDFKWLHTFVTAAKYENFRKTAETLFLSQPTVTVHIKLLEKEISCKLFQRSGRKIQLTEEGKAYVPFAMRLLEDYENSMA
ELHRVRQGYSHTLTLAVSPLIADTVLPSVMKRYTEDNKETEMTVTIFESEEIASQIRNGSADIGLSCLKVQSSSLTCRPL
YNDPVVLVAPPGRKPGTGKADEVKDLFGQYLLLTHNHPDYWDDLLRQVRIQFPFVRTMKVTQTHITKRFIKEGLGVSFLP
LSAVRAELAAGSMIEIPCEFAQMPSAGAYAIALYENEKKKTFLDFLSHFHF

Sequences:

>Translated_291_residues
MDFKWLHTFVTAAKYENFRKTAETLFLSQPTVTVHIKLLEKEISCKLFQRSGRKIQLTEEGKAYVPFAMRLLEDYENSMA
ELHRVRQGYSHTLTLAVSPLIADTVLPSVMKRYTEDNKETEMTVTIFESEEIASQIRNGSADIGLSCLKVQSSSLTCRPL
YNDPVVLVAPPGRKPGTGKADEVKDLFGQYLLLTHNHPDYWDDLLRQVRIQFPFVRTMKVTQTHITKRFIKEGLGVSFLP
LSAVRAELAAGSMIEIPCEFAQMPSAGAYAIALYENEKKKTFLDFLSHFHF
>Mature_291_residues
MDFKWLHTFVTAAKYENFRKTAETLFLSQPTVTVHIKLLEKEISCKLFQRSGRKIQLTEEGKAYVPFAMRLLEDYENSMA
ELHRVRQGYSHTLTLAVSPLIADTVLPSVMKRYTEDNKETEMTVTIFESEEIASQIRNGSADIGLSCLKVQSSSLTCRPL
YNDPVVLVAPPGRKPGTGKADEVKDLFGQYLLLTHNHPDYWDDLLRQVRIQFPFVRTMKVTQTHITKRFIKEGLGVSFLP
LSAVRAELAAGSMIEIPCEFAQMPSAGAYAIALYENEKKKTFLDFLSHFHF

Specific function: Negative regulatory protein for the citA gene for citrate synthase I [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082132, Length=268, Percent_Identity=26.865671641791, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=25.938566552901, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87081904, Length=144, Percent_Identity=30.5555555555556, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=24.406779661017, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790399, Length=264, Percent_Identity=22.3484848484848, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788296, Length=200, Percent_Identity=30, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=284, Percent_Identity=21.830985915493, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI145693105, Length=237, Percent_Identity=23.6286919831224, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI157672245, Length=168, Percent_Identity=25.5952380952381, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790783, Length=281, Percent_Identity=23.1316725978648, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=256, Percent_Identity=23.828125, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=164, Percent_Identity=26.219512195122, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=23.7931034482759, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788706, Length=256, Percent_Identity=25.78125, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789639, Length=253, Percent_Identity=24.1106719367589, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1787530, Length=239, Percent_Identity=25.5230125523013, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33119; Mature: 33119

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKWLHTFVTAAKYENFRKTAETLFLSQPTVTVHIKLLEKEISCKLFQRSGRKIQLTEE
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEHHHHHHHHHHCCCCEEEEECC
GKAYVPFAMRLLEDYENSMAELHRVRQGYSHTLTLAVSPLIADTVLPSVMKRYTEDNKET
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCC
EMTVTIFESEEIASQIRNGSADIGLSCLKVQSSSLTCRPLYNDPVVLVAPPGRKPGTGKA
EEEEEEECCHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCEEEEECCCCCCCCCCH
DEVKDLFGQYLLLTHNHPDYWDDLLRQVRIQFPFVRTMKVTQTHITKRFIKEGLGVSFLP
HHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEH
LSAVRAELAAGSMIEIPCEFAQMPSAGAYAIALYENEKKKTFLDFLSHFHF
HHHHHHHHHCCCEEECCHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDFKWLHTFVTAAKYENFRKTAETLFLSQPTVTVHIKLLEKEISCKLFQRSGRKIQLTEE
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEHHHHHHHHHHCCCCEEEEECC
GKAYVPFAMRLLEDYENSMAELHRVRQGYSHTLTLAVSPLIADTVLPSVMKRYTEDNKET
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCC
EMTVTIFESEEIASQIRNGSADIGLSCLKVQSSSLTCRPLYNDPVVLVAPPGRKPGTGKA
EEEEEEECCHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCEEEEECCCCCCCCCCH
DEVKDLFGQYLLLTHNHPDYWDDLLRQVRIQFPFVRTMKVTQTHITKRFIKEGLGVSFLP
HHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEH
LSAVRAELAAGSMIEIPCEFAQMPSAGAYAIALYENEKKKTFLDFLSHFHF
HHHHHHHHHCCCEEECCHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045898; 9579061; 9384377; 8045899 [H]