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The map label for this gene is fhuC [C]

Identifier: 154248625

GI number: 154248625

Start: 5220495

End: 5221235

Strand: Direct

Name: fhuC [C]

Synonym: Xaut_4707

Alternate gene names: 154248625

Gene position: 5220495-5221235 (Clockwise)

Preceding gene: 154248624

Following gene: 154248626

Centisome position: 98.33

GC content: 70.72

Gene sequence:

>741_bases
GTGACCGCCCAGATCTCCTTCCGCAACCTGACCCTCGGCTATGAGCGCCACCCCGCCGTCCATCACCTGTCGGGCGATGT
GCGCGAGGGCGCGCTGCTCGCCGTGTGCGGATCCAACGGCGCCGGCAAATCCACCCTGCTGAAGGGCATCTGCGGCGCGC
TTAAGCCGCTCGGCGGCGCCATCGACCTCCACGGCGTCTCCCCGCGCGACATCGCCTACCTGCCGCAGGGCGCCGAGATC
GACCGCAGCTTCCCCATCAATGTTTACGACATGGTGTCCATGGGCCTGTGGCGGCGCGCCGGCCTGTTCGGTGGCATCGG
CCGCGCCGACCGGCAGCACATCGCCGATGCCATCGCCGCCGTGGGCCTGGAAGGCTTCGAGGCGCGCCCCATCGGCACGC
TGTCCGGCGGGCAGATGCAGCGCACCCTGTTCGCCCGCCTGCTGCTGCAGGACGCCCGCGTGATCCTTCTGGACGAGCCC
TTCACCGCCCTCGACGCCAAGACCGTGTCCGACCTCGTGGACCTGGTGCGGCGCTGGCACGGCGAGAAGCGCACGGTGAT
CGCGGTGCTGCACGATTTCGATCTGGTCCGCACCACCTTCCCTGAGACGCTGCTCCTGGCCCGGACCCCGGTGGCCTGGG
GCCCGACCTCGGAAGCGCTGGGCGCGGAGAACCTGCTTAAGGCGCGCCGCATGGGCGAAGCCTGGCGGGAGGATGCCCCG
GACTGTTCCGACGCGGCCTGA

Upstream 100 bases:

>100_bases
CCTCGGTGCTGCGGCTCTCCCTTCTCGCCCGCCTCGCCATCGCCGGCACGCTGCTGGCGGTGTTGTGGACCGTCGTCTCC
CTCGTGGTGGGGAGCGAGCC

Downstream 100 bases:

>100_bases
GCGCGCCCGCACCGCACGTTTATCGCCGGCCCTTTGCTTGGCCGGGAGCCGGGAAAAGGCTGTCCAACCCCGGTCCGGTT
TCAGCCCCCAACCGGACCCT

Product: ABC transporter-like protein

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTAQISFRNLTLGYERHPAVHHLSGDVREGALLAVCGSNGAGKSTLLKGICGALKPLGGAIDLHGVSPRDIAYLPQGAEI
DRSFPINVYDMVSMGLWRRAGLFGGIGRADRQHIADAIAAVGLEGFEARPIGTLSGGQMQRTLFARLLLQDARVILLDEP
FTALDAKTVSDLVDLVRRWHGEKRTVIAVLHDFDLVRTTFPETLLLARTPVAWGPTSEALGAENLLKARRMGEAWREDAP
DCSDAA

Sequences:

>Translated_246_residues
MTAQISFRNLTLGYERHPAVHHLSGDVREGALLAVCGSNGAGKSTLLKGICGALKPLGGAIDLHGVSPRDIAYLPQGAEI
DRSFPINVYDMVSMGLWRRAGLFGGIGRADRQHIADAIAAVGLEGFEARPIGTLSGGQMQRTLFARLLLQDARVILLDEP
FTALDAKTVSDLVDLVRRWHGEKRTVIAVLHDFDLVRTTFPETLLLARTPVAWGPTSEALGAENLLKARRMGEAWREDAP
DCSDAA
>Mature_245_residues
TAQISFRNLTLGYERHPAVHHLSGDVREGALLAVCGSNGAGKSTLLKGICGALKPLGGAIDLHGVSPRDIAYLPQGAEID
RSFPINVYDMVSMGLWRRAGLFGGIGRADRQHIADAIAAVGLEGFEARPIGTLSGGQMQRTLFARLLLQDARVILLDEPF
TALDAKTVSDLVDLVRRWHGEKRTVIAVLHDFDLVRTTFPETLLLARTPVAWGPTSEALGAENLLKARRMGEAWREDAPD
CSDAA

Specific function: Part of an ATP-driven transport system CPn0346/CPn0347/CPn0348/CPn0349 for a metal. Probably responsible for energy coupling to the transport system [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI157502203, Length=191, Percent_Identity=33.5078534031414, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI157502201, Length=191, Percent_Identity=33.5078534031414, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI153792144, Length=157, Percent_Identity=31.8471337579618, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786345, Length=201, Percent_Identity=36.318407960199, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1786803, Length=202, Percent_Identity=33.1683168316832, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1786563, Length=215, Percent_Identity=35.3488372093023, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790739, Length=230, Percent_Identity=30.8695652173913, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788165, Length=207, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790544, Length=249, Percent_Identity=28.1124497991968, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788225, Length=205, Percent_Identity=29.7560975609756, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081709, Length=198, Percent_Identity=30.3030303030303, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787041, Length=211, Percent_Identity=29.8578199052133, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786253, Length=217, Percent_Identity=33.6405529953917, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788761, Length=196, Percent_Identity=30.6122448979592, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787712, Length=202, Percent_Identity=32.6732673267327, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=31.0679611650485, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994943, Length=192, Percent_Identity=29.6875, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788450, Length=203, Percent_Identity=32.512315270936, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI48995001, Length=187, Percent_Identity=29.9465240641711, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789032, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789593, Length=245, Percent_Identity=27.3469387755102, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788210, Length=205, Percent_Identity=26.3414634146341, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI87081782, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082268, Length=248, Percent_Identity=25, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788053, Length=205, Percent_Identity=30.2439024390244, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=190, Percent_Identity=35.7894736842105, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787182, Length=188, Percent_Identity=31.3829787234043, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787105, Length=193, Percent_Identity=30.5699481865285, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788897, Length=215, Percent_Identity=26.9767441860465, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789873, Length=181, Percent_Identity=30.939226519337, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787112, Length=200, Percent_Identity=33.5, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789864, Length=237, Percent_Identity=24.8945147679325, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787547, Length=256, Percent_Identity=29.6875, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=213, Percent_Identity=30.9859154929577, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=207, Percent_Identity=28.9855072463768, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=203, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321121, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325030, Length=167, Percent_Identity=31.1377245508982, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550390, Length=205, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574744, Length=213, Percent_Identity=30.9859154929577, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45552805, Length=170, Percent_Identity=31.1764705882353, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17647219, Length=170, Percent_Identity=31.1764705882353, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28574533, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585091, Length=207, Percent_Identity=28.5024154589372, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26558; Mature: 26427

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQISFRNLTLGYERHPAVHHLSGDVREGALLAVCGSNGAGKSTLLKGICGALKPLGGA
CCCEEEECEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
IDLHGVSPRDIAYLPQGAEIDRSFPINVYDMVSMGLWRRAGLFGGIGRADRQHIADAIAA
EEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VGLEGFEARPIGTLSGGQMQRTLFARLLLQDARVILLDEPFTALDAKTVSDLVDLVRRWH
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
GEKRTVIAVLHDFDLVRTTFPETLLLARTPVAWGPTSEALGAENLLKARRMGEAWREDAP
CCCCEEEEEEHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHCCC
DCSDAA
CCCCCC
>Mature Secondary Structure 
TAQISFRNLTLGYERHPAVHHLSGDVREGALLAVCGSNGAGKSTLLKGICGALKPLGGA
CCEEEECEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
IDLHGVSPRDIAYLPQGAEIDRSFPINVYDMVSMGLWRRAGLFGGIGRADRQHIADAIAA
EEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VGLEGFEARPIGTLSGGQMQRTLFARLLLQDARVILLDEPFTALDAKTVSDLVDLVRRWH
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
GEKRTVIAVLHDFDLVRTTFPETLLLARTPVAWGPTSEALGAENLLKARRMGEAWREDAP
CCCCEEEEEEHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHCCC
DCSDAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]