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The map label for this gene is pkn1 [H]

Identifier: 154248609

GI number: 154248609

Start: 5201071

End: 5201991

Strand: Direct

Name: pkn1 [H]

Synonym: Xaut_4691

Alternate gene names: 154248609

Gene position: 5201071-5201991 (Clockwise)

Preceding gene: 154248605

Following gene: 154248610

Centisome position: 97.97

GC content: 68.08

Gene sequence:

>921_bases
ATGGTGTGGATCCCAGGCGGAACCTTCCATATGGGCTCGGATGCGCACTATCTCGAAGAGGCTCCCGTGCGCGAGGTCGC
GGTCGACGGTTTCTGGATGGATCGCTGCCCGGTCACCAACCGCGATTTCGCCCGCTTCGTCGCCGAGACGGGCCACGTCT
CGCTCGCCGAGCAGGTCCCTTCCATCGAGGATTATCCCGGAGCCGACCCGCTGTTGCTTGTGGCCGGCTCGCTGGTGTTC
GTCACGCCCGACGCGCCGGGCGACAGCGCGGATTGGACGCGCTGGTGGCGCTTCGTGGCGGGTGCGAACTGGCGCCATCC
GCAGGGCCCGGACAGCAGCATCGAAGGGCTCGAAGATCATCCTGTCGTCCATGTCTGCCACGGCGATGCGCTGGCCTATG
CCCGCTGGCAAGGCAAGGAACTGCCGAGCGAGGCCCAATGGGAATATGCGGCGCGCGGCGGCCTTGACCGGGCGGAGTTT
GCCTGGGGCGATGCGCTGGTGCCGGATGGCGTTCACCGCGCCAATACGTGGCAGGGGCACTTCCCGGACGAGAACCTCGC
GCTCGACGGCTATGCCGGCACCTCGCCTGTCACGGCCTTCCCGCCCAACGGCTACGGCCTGCTCGATATGATCGGCAATG
TGTGGGAATGGACCGACGACTGGTACCGACCCCACGGTGCCTCAGCCCAGGGGAAGGCGTGCTGCCTGCCCCGCAACCCG
CGCGGGGGCAGCGCGGAGGAAAGCCGCGATCCTGAGGCGCCCGGTTCCGCGCTTCCCCGCAAGGTGCTGAAAGGCGGGTC
GCATCTGTGCGCCCCCAATTACTGCCGGCGCTATCGCCCCGCCGCGCGCCAGCCCCAGACCATTGACACCGCCTCCGTGC
ACATCGGCTTCCGATGTGTCCGAAAGGTTGCGACCCCCTGA

Upstream 100 bases:

>100_bases
CAGATCCGTGAGGTGATGCGTGGGCGAGGCTTCCATCGGCCATCCCCGTCCCAGGGACGAGCCGTCGCGGGGATTGGCCG
CCTCAGATCAGGATGCCGAC

Downstream 100 bases:

>100_bases
GGAGCTCTCGATGACTGACACACCCGCATCTGCCGACGACGACCGCTCGCAGCCGAGCCGTCGCGATGTGCTCGCCGGGG
GCGCCGGATTCCTGGCCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MVWIPGGTFHMGSDAHYLEEAPVREVAVDGFWMDRCPVTNRDFARFVAETGHVSLAEQVPSIEDYPGADPLLLVAGSLVF
VTPDAPGDSADWTRWWRFVAGANWRHPQGPDSSIEGLEDHPVVHVCHGDALAYARWQGKELPSEAQWEYAARGGLDRAEF
AWGDALVPDGVHRANTWQGHFPDENLALDGYAGTSPVTAFPPNGYGLLDMIGNVWEWTDDWYRPHGASAQGKACCLPRNP
RGGSAEESRDPEAPGSALPRKVLKGGSHLCAPNYCRRYRPAARQPQTIDTASVHIGFRCVRKVATP

Sequences:

>Translated_306_residues
MVWIPGGTFHMGSDAHYLEEAPVREVAVDGFWMDRCPVTNRDFARFVAETGHVSLAEQVPSIEDYPGADPLLLVAGSLVF
VTPDAPGDSADWTRWWRFVAGANWRHPQGPDSSIEGLEDHPVVHVCHGDALAYARWQGKELPSEAQWEYAARGGLDRAEF
AWGDALVPDGVHRANTWQGHFPDENLALDGYAGTSPVTAFPPNGYGLLDMIGNVWEWTDDWYRPHGASAQGKACCLPRNP
RGGSAEESRDPEAPGSALPRKVLKGGSHLCAPNYCRRYRPAARQPQTIDTASVHIGFRCVRKVATP
>Mature_306_residues
MVWIPGGTFHMGSDAHYLEEAPVREVAVDGFWMDRCPVTNRDFARFVAETGHVSLAEQVPSIEDYPGADPLLLVAGSLVF
VTPDAPGDSADWTRWWRFVAGANWRHPQGPDSSIEGLEDHPVVHVCHGDALAYARWQGKELPSEAQWEYAARGGLDRAEF
AWGDALVPDGVHRANTWQGHFPDENLALDGYAGTSPVTAFPPNGYGLLDMIGNVWEWTDDWYRPHGASAQGKACCLPRNP
RGGSAEESRDPEAPGSALPRKVLKGGSHLCAPNYCRRYRPAARQPQTIDTASVHIGFRCVRKVATP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=303, Percent_Identity=44.2244224422442, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI257470975, Length=303, Percent_Identity=43.2343234323432, Blast_Score=240, Evalue=9e-64,
Organism=Homo sapiens, GI257470977, Length=303, Percent_Identity=41.2541254125413, Blast_Score=224, Evalue=6e-59,
Organism=Homo sapiens, GI194248088, Length=312, Percent_Identity=39.1025641025641, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI194248087, Length=309, Percent_Identity=36.5695792880259, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI226437577, Length=213, Percent_Identity=41.7840375586854, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI194248090, Length=212, Percent_Identity=42.4528301886792, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI20130397, Length=309, Percent_Identity=40.7766990291262, Blast_Score=221, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33592; Mature: 33592

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWIPGGTFHMGSDAHYLEEAPVREVAVDGFWMDRCPVTNRDFARFVAETGHVSLAEQVP
CEECCCCCEECCCCCHHHHHCCHHHHEECCEEECCCCCCCHHHHHHHHHCCCEEHHHHCC
SIEDYPGADPLLLVAGSLVFVTPDAPGDSADWTRWWRFVAGANWRHPQGPDSSIEGLEDH
CCCCCCCCCHHEEEECCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PVVHVCHGDALAYARWQGKELPSEAQWEYAARGGLDRAEFAWGDALVPDGVHRANTWQGH
CEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCC
FPDENLALDGYAGTSPVTAFPPNGYGLLDMIGNVWEWTDDWYRPHGASAQGKACCLPRNP
CCCCCEEECCCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCCC
RGGSAEESRDPEAPGSALPRKVLKGGSHLCAPNYCRRYRPAARQPQTIDTASVHIGFRCV
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHH
RKVATP
HHHCCC
>Mature Secondary Structure
MVWIPGGTFHMGSDAHYLEEAPVREVAVDGFWMDRCPVTNRDFARFVAETGHVSLAEQVP
CEECCCCCEECCCCCHHHHHCCHHHHEECCEEECCCCCCCHHHHHHHHHCCCEEHHHHCC
SIEDYPGADPLLLVAGSLVFVTPDAPGDSADWTRWWRFVAGANWRHPQGPDSSIEGLEDH
CCCCCCCCCHHEEEECCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PVVHVCHGDALAYARWQGKELPSEAQWEYAARGGLDRAEFAWGDALVPDGVHRANTWQGH
CEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCC
FPDENLALDGYAGTSPVTAFPPNGYGLLDMIGNVWEWTDDWYRPHGASAQGKACCLPRNP
CCCCCEEECCCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCCC
RGGSAEESRDPEAPGSALPRKVLKGGSHLCAPNYCRRYRPAARQPQTIDTASVHIGFRCV
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHH
RKVATP
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]