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The map label for this gene is gstB [H]

Identifier: 154248602

GI number: 154248602

Start: 5188496

End: 5189140

Strand: Reverse

Name: gstB [H]

Synonym: Xaut_4683

Alternate gene names: 154248602

Gene position: 5189140-5188496 (Counterclockwise)

Preceding gene: 154248604

Following gene: 154248599

Centisome position: 97.74

GC content: 64.5

Gene sequence:

>645_bases
ATGGCACTGAAATTCTACATGACGCCGGGTTCGTGTTCGACCGGCATCCACATCCTGCTCGAAACGCTGGAACTGCCGTT
CGAGGTCTGGGTCATCAACATTCCGGCCGGCGACCACCTGCGCCCGGAATATCTCAAGATCAATCCGAGGGGCACGATCC
CCAGCCTCGTGCTCGATGACGGCACCGCCCTCACCGATTTCAAGTCCATCGCGCTGTGGCTGGCGCAGACCTACCCGCGC
GCCAAGCTCCTGCCGGACGATCCCGCGCTGGCGGCGCAAGCGGTGGACCTGCTGGAATTCGCGCTGATCCAGCTGCATGG
CGAGGGCTTCACCCGCATCTTCACCTCCGAACGCTACATATCGTCGGGCGGCGCGAAGCCCGGACAGCAACTGAAGGACG
ACGTGACCTCCCATGGCCGGGAGATCGTCGAGCAGGCATTCGCAGTGCTGGAAAAGCGTCTGCCGGCCGAGGGCTATGCG
GTTGGACCGGCTTTCTCCATTGCCGACGCGGCGTTGTTCTACAACGAGTTCTGGGCGGAAAAGACCGGCATTCCCATGCC
GCCGCGCGTGCTCGCCCACTACCAGCGGGTGCGGGCGCGGCCGGTGGTGAGGCAGGTGCTGGCCGAGGAAGGCTACCGCA
CCTGA

Upstream 100 bases:

>100_bases
AAAGGCCCGTCGCTGCCGCCACGGGGGCCGGCGGCCGCGTCGTTCAGCGCGGGACAGTGTCGGGATTCGGTCATGGCGGC
GTTCTTGCTTGGCGCGCGCC

Downstream 100 bases:

>100_bases
TCCATGGGGCTCAGCGCAACTGGGGCAAGGGCAGGGGGAGTAGCGCCTGTAGCACCGCCACAAGCTGGGCCGAGGCCGGC
TGCTCCTCCCTCACGTTCTG

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MALKFYMTPGSCSTGIHILLETLELPFEVWVINIPAGDHLRPEYLKINPRGTIPSLVLDDGTALTDFKSIALWLAQTYPR
AKLLPDDPALAAQAVDLLEFALIQLHGEGFTRIFTSERYISSGGAKPGQQLKDDVTSHGREIVEQAFAVLEKRLPAEGYA
VGPAFSIADAALFYNEFWAEKTGIPMPPRVLAHYQRVRARPVVRQVLAEEGYRT

Sequences:

>Translated_214_residues
MALKFYMTPGSCSTGIHILLETLELPFEVWVINIPAGDHLRPEYLKINPRGTIPSLVLDDGTALTDFKSIALWLAQTYPR
AKLLPDDPALAAQAVDLLEFALIQLHGEGFTRIFTSERYISSGGAKPGQQLKDDVTSHGREIVEQAFAVLEKRLPAEGYA
VGPAFSIADAALFYNEFWAEKTGIPMPPRVLAHYQRVRARPVVRQVLAEEGYRT
>Mature_213_residues
ALKFYMTPGSCSTGIHILLETLELPFEVWVINIPAGDHLRPEYLKINPRGTIPSLVLDDGTALTDFKSIALWLAQTYPRA
KLLPDDPALAAQAVDLLEFALIQLHGEGFTRIFTSERYISSGGAKPGQQLKDDVTSHGREIVEQAFAVLEKRLPAEGYAV
GPAFSIADAALFYNEFWAEKTGIPMPPRVLAHYQRVRARPVVRQVLAEEGYRT

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=222, Percent_Identity=29.7297297297297, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17864594, Length=172, Percent_Identity=31.3953488372093, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17864592, Length=173, Percent_Identity=30.635838150289, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI85725204, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737923, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17933730, Length=171, Percent_Identity=30.4093567251462, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 23749; Mature: 23617

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKFYMTPGSCSTGIHILLETLELPFEVWVINIPAGDHLRPEYLKINPRGTIPSLVLDD
CEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEECC
GTALTDFKSIALWLAQTYPRAKLLPDDPALAAQAVDLLEFALIQLHGEGFTRIFTSERYI
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHCHHHH
SSGGAKPGQQLKDDVTSHGREIVEQAFAVLEKRLPAEGYAVGPAFSIADAALFYNEFWAE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHH
KTGIPMPPRVLAHYQRVRARPVVRQVLAEEGYRT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALKFYMTPGSCSTGIHILLETLELPFEVWVINIPAGDHLRPEYLKINPRGTIPSLVLDD
EEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEECC
GTALTDFKSIALWLAQTYPRAKLLPDDPALAAQAVDLLEFALIQLHGEGFTRIFTSERYI
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHCHHHH
SSGGAKPGQQLKDDVTSHGREIVEQAFAVLEKRLPAEGYAVGPAFSIADAALFYNEFWAE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHH
KTGIPMPPRVLAHYQRVRARPVVRQVLAEEGYRT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]