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The map label for this gene is exoB [H]

Identifier: 154248598

GI number: 154248598

Start: 5183503

End: 5184519

Strand: Reverse

Name: exoB [H]

Synonym: Xaut_4679

Alternate gene names: 154248598

Gene position: 5184519-5183503 (Counterclockwise)

Preceding gene: 154248599

Following gene: 154248593

Centisome position: 97.66

GC content: 67.75

Gene sequence:

>1017_bases
ATGTCAGTGCTTGTGACCGGCGGTGCCGGCTATATCGGAAGCCATGCTGTTCTCGAGCTGGTCGGGCGCGGGGAAAGCGT
CACCGTGCTGGACGACCTCTCCACCGGCTTCGACTGGGCCGTGCCGGAAGCGATCGACCTGGTGGTGGGTGACGTGGGCG
ACGCCGTTTTCATGCGGCGCCTGCTGGAAGAGCGCGGCATCACCGAGATCATCCATTTCGCGGCCCGGAGCCTGGTGGCG
GAATCGGTGGCGGACCCGCTCGGCTATTATTTCGGCAACATCGTGAAGACCCGCACCCTGATCCAGACCGCGATCGAGGC
CGGGGTGACGCGGATGATTTTTTCCTCCTCCGCCTCGGTCTACGGCGAGCCGGTGGTGGACATCATCGGCGAGGACGAGC
CCACCGTCCCCATCAATCCCTACGGCCGCTCCAAGCTGGCGAGCGAATGGATGCTGGAGGACGCGGCCCGCGCCCACGGC
CTCGTCTACACGGCGCTGCGCTATTTCAACGTGGCCGGCGCCGATCCGCTGGGGCGCTCGGGCCAGTCGTCCCGCGTCGC
CACCCACCTCATCAAGATCGCGAGTCAGGTGGCGGCGGGCGCAAGGCCGGGCCTTGAGATCTACGGCACCGACTATCCTA
CGCGGGATGGCACCTGCATCCGCGACTATATCCACGTCACCGATCTCGCCCGGGCCCATGTGGCGGCGCTGGAGCGCCTG
CGGGCCGGCGGCGGGAGCCTGAAGGTGAATTGCGGCTACGGCCGCGGCTATTCCGTGAAGGAGGTGGTGGACGTGGTGAA
GGAGGTGTCCGGCATCGACTTTCCGGTGACGCTCTCGCCGCGTCGGCCGGGCGATCCGGCTTGCCTGGTGGCCAGGGCCG
ACCGCGTTCGCGCCGAACTCGGTTGGGAACCGACCCTCGACCATCTGCCCACCATCGTCGGTCATGCCATCGAGTGGGAA
AAGCGCCTGGAACGGCGCAAGGCCGCGCAACGGGCCGCCGCCAGCAGCGTGGCCTGA

Upstream 100 bases:

>100_bases
CCGGAGTGGTTATCGCAATGGTATTTCGTCCACCGCCTGGCTGTGGCGGAGCGGGACGCGGCGGCGCGTCTCTTGTTTGA
ATGTTGGGGCGGCAACCTTA

Downstream 100 bases:

>100_bases
CGCAGTCCGATCAGATCGCATCGCGATCTGATCGGCAGGAGCGTGATAGACTTGAGGTGCGAAGACCGGCCCGTCAGCCG
ACCGCGATCTCCTTGCCGCT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSVLVTGGAGYIGSHAVLELVGRGESVTVLDDLSTGFDWAVPEAIDLVVGDVGDAVFMRRLLEERGITEIIHFAARSLVA
ESVADPLGYYFGNIVKTRTLIQTAIEAGVTRMIFSSSASVYGEPVVDIIGEDEPTVPINPYGRSKLASEWMLEDAARAHG
LVYTALRYFNVAGADPLGRSGQSSRVATHLIKIASQVAAGARPGLEIYGTDYPTRDGTCIRDYIHVTDLARAHVAALERL
RAGGGSLKVNCGYGRGYSVKEVVDVVKEVSGIDFPVTLSPRRPGDPACLVARADRVRAELGWEPTLDHLPTIVGHAIEWE
KRLERRKAAQRAAASSVA

Sequences:

>Translated_338_residues
MSVLVTGGAGYIGSHAVLELVGRGESVTVLDDLSTGFDWAVPEAIDLVVGDVGDAVFMRRLLEERGITEIIHFAARSLVA
ESVADPLGYYFGNIVKTRTLIQTAIEAGVTRMIFSSSASVYGEPVVDIIGEDEPTVPINPYGRSKLASEWMLEDAARAHG
LVYTALRYFNVAGADPLGRSGQSSRVATHLIKIASQVAAGARPGLEIYGTDYPTRDGTCIRDYIHVTDLARAHVAALERL
RAGGGSLKVNCGYGRGYSVKEVVDVVKEVSGIDFPVTLSPRRPGDPACLVARADRVRAELGWEPTLDHLPTIVGHAIEWE
KRLERRKAAQRAAASSVA
>Mature_337_residues
SVLVTGGAGYIGSHAVLELVGRGESVTVLDDLSTGFDWAVPEAIDLVVGDVGDAVFMRRLLEERGITEIIHFAARSLVAE
SVADPLGYYFGNIVKTRTLIQTAIEAGVTRMIFSSSASVYGEPVVDIIGEDEPTVPINPYGRSKLASEWMLEDAARAHGL
VYTALRYFNVAGADPLGRSGQSSRVATHLIKIASQVAAGARPGLEIYGTDYPTRDGTCIRDYIHVTDLARAHVAALERLR
AGGGSLKVNCGYGRGYSVKEVVDVVKEVSGIDFPVTLSPRRPGDPACLVARADRVRAELGWEPTLDHLPTIVGHAIEWEK
RLERRKAAQRAAASSVA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=38.7573964497041, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=38.7573964497041, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=38.7573964497041, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI7657641, Length=346, Percent_Identity=26.0115606936416, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=26.1146496815287, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI116268111, Length=294, Percent_Identity=26.8707482993197, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=40.2985074626866, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1790049, Length=293, Percent_Identity=30.7167235494881, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994969, Length=336, Percent_Identity=25.8928571428571, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788353, Length=357, Percent_Identity=26.3305322128852, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=321, Percent_Identity=40.809968847352, Blast_Score=210, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI71982038, Length=323, Percent_Identity=40.5572755417957, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17568069, Length=249, Percent_Identity=27.3092369477912, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=322, Percent_Identity=40.3726708074534, Blast_Score=212, Evalue=7e-56,
Organism=Drosophila melanogaster, GI19923002, Length=320, Percent_Identity=39.6875, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=25.1592356687898, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36268; Mature: 36136

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVTGGAGYIGSHAVLELVGRGESVTVLDDLSTGFDWAVPEAIDLVVGDVGDAVFMRR
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHH
LLEERGITEIIHFAARSLVAESVADPLGYYFGNIVKTRTLIQTAIEAGVTRMIFSSSASV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YGEPVVDIIGEDEPTVPINPYGRSKLASEWMLEDAARAHGLVYTALRYFNVAGADPLGRS
CCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQSSRVATHLIKIASQVAAGARPGLEIYGTDYPTRDGTCIRDYIHVTDLARAHVAALERL
CCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAGGGSLKVNCGYGRGYSVKEVVDVVKEVSGIDFPVTLSPRRPGDPACLVARADRVRAEL
HCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEHHHHHHHHHC
GWEPTLDHLPTIVGHAIEWEKRLERRKAAQRAAASSVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLVTGGAGYIGSHAVLELVGRGESVTVLDDLSTGFDWAVPEAIDLVVGDVGDAVFMRR
EEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHH
LLEERGITEIIHFAARSLVAESVADPLGYYFGNIVKTRTLIQTAIEAGVTRMIFSSSASV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YGEPVVDIIGEDEPTVPINPYGRSKLASEWMLEDAARAHGLVYTALRYFNVAGADPLGRS
CCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQSSRVATHLIKIASQVAAGARPGLEIYGTDYPTRDGTCIRDYIHVTDLARAHVAALERL
CCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAGGGSLKVNCGYGRGYSVKEVVDVVKEVSGIDFPVTLSPRRPGDPACLVARADRVRAEL
HCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEHHHHHHHHHC
GWEPTLDHLPTIVGHAIEWEKRLERRKAAQRAAASSVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]