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The map label for this gene is dgdR [H]

Identifier: 154248572

GI number: 154248572

Start: 5142874

End: 5143827

Strand: Direct

Name: dgdR [H]

Synonym: Xaut_4653

Alternate gene names: 154248572

Gene position: 5142874-5143827 (Clockwise)

Preceding gene: 154248570

Following gene: 154248583

Centisome position: 96.87

GC content: 68.87

Gene sequence:

>954_bases
ATGAATCAAGCTAGCGAATGTTTTTCATCTCACGTATCATTCTGCGTGATGAATGCTCCGGAACCGCACCCCATGACGGT
GATGCTCGACCCCGACCAGCTGCGCACATTCGTGGCCATTGCCGAGACCGGCAGCTTCACCCGTGCGGCGGAGGTGGTGC
ACAAGACGCAGTCCGCCGTCTCCATGCAGATGAAGCGCCTGGAGGAGCGCGTGGGCCGCCCGGTGTTCATGCGCGACGGC
CGCGCCTCGCGCCTGACCGAGGACGGCGAGCGCCTGCTCGATTATGCCCGGCGCATCGTCAAGCTGAACGTGGAAGCGGT
GCTCAGCTTCGCCGATGCCGCCCTGTCGGGGCGGGTCTGCCTGGGGGTGCCGGACGATTACGCCGACCGCTACCTGCCGG
ACATCATGGCCCGCTTCTCGCGGACCCATCCCTCGGTGGAGCTGACCGTGCTGTGCGAGCCGTCGAGCGAACTGGTGCAG
CACATCGCCGGCGGCACCATCGACCTCGCCATCATCACCGCGACCGAGATCACCGCCCGGAACGCCCACGTCATCCGCCG
CGAGCGGCTTTTGTGGGTGTCCTCGGCGCGGCACAGCGTGCATCTGGAGACGCCGGTGCCGCTGGCGCTGGGCCGAACCA
CCTGCCAGTGGCGCGATATCGCCGTCTCCCGGCTGGTCGGGGCGGGGCGCAGCCACCGCATCCTCTACACCAGCCCCAAC
AGCGGCGCGGTGGCGGCGGCGGTGCTGGCTGGTCTCGCGGTCTCGGTGCTGCCGGAATCGGCGCTGCGCACCGGCATGCG
CGTGCTCGGCAGCGCCGACGGCTATCCGCCCCTACCCCCGTGCGACATCGGCCTGCTGCGCAATCGCCACGAGCCGTCGC
TGCTGGCGGACGCGCTGGCCCAGCACATCGTGCAGGGCCTCGACAACCTCACGGATGCTGAAGCGGCGCAGTGA

Upstream 100 bases:

>100_bases
GGTGGGGATCGCGGACAGTCCTTTCGTGGGTCCCAGGGGCTCCTCGAGCCACCCGATTTCGTATCCCGCCGCTTCGGCGC
GCCCTTTGTGACCCCCCGGC

Downstream 100 bases:

>100_bases
CGCCACTCACGCCGCGCCGCCCTCACACACTCTCGGCGTAACGCTCGTAGGCAACCTCGACGGTGAGGATGTGGGCGCGC
ATGGCGGCGGCGGCCTCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNQASECFSSHVSFCVMNAPEPHPMTVMLDPDQLRTFVAIAETGSFTRAAEVVHKTQSAVSMQMKRLEERVGRPVFMRDG
RASRLTEDGERLLDYARRIVKLNVEAVLSFADAALSGRVCLGVPDDYADRYLPDIMARFSRTHPSVELTVLCEPSSELVQ
HIAGGTIDLAIITATEITARNAHVIRRERLLWVSSARHSVHLETPVPLALGRTTCQWRDIAVSRLVGAGRSHRILYTSPN
SGAVAAAVLAGLAVSVLPESALRTGMRVLGSADGYPPLPPCDIGLLRNRHEPSLLADALAQHIVQGLDNLTDAEAAQ

Sequences:

>Translated_317_residues
MNQASECFSSHVSFCVMNAPEPHPMTVMLDPDQLRTFVAIAETGSFTRAAEVVHKTQSAVSMQMKRLEERVGRPVFMRDG
RASRLTEDGERLLDYARRIVKLNVEAVLSFADAALSGRVCLGVPDDYADRYLPDIMARFSRTHPSVELTVLCEPSSELVQ
HIAGGTIDLAIITATEITARNAHVIRRERLLWVSSARHSVHLETPVPLALGRTTCQWRDIAVSRLVGAGRSHRILYTSPN
SGAVAAAVLAGLAVSVLPESALRTGMRVLGSADGYPPLPPCDIGLLRNRHEPSLLADALAQHIVQGLDNLTDAEAAQ
>Mature_317_residues
MNQASECFSSHVSFCVMNAPEPHPMTVMLDPDQLRTFVAIAETGSFTRAAEVVHKTQSAVSMQMKRLEERVGRPVFMRDG
RASRLTEDGERLLDYARRIVKLNVEAVLSFADAALSGRVCLGVPDDYADRYLPDIMARFSRTHPSVELTVLCEPSSELVQ
HIAGGTIDLAIITATEITARNAHVIRRERLLWVSSARHSVHLETPVPLALGRTTCQWRDIAVSRLVGAGRSHRILYTSPN
SGAVAAAVLAGLAVSVLPESALRTGMRVLGSADGYPPLPPCDIGLLRNRHEPSLLADALAQHIVQGLDNLTDAEAAQ

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=283, Percent_Identity=36.3957597173145, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787806, Length=246, Percent_Identity=26.4227642276423, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790208, Length=284, Percent_Identity=27.8169014084507, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI157672245, Length=131, Percent_Identity=36.6412213740458, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786713, Length=70, Percent_Identity=51.4285714285714, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=140, Percent_Identity=27.8571428571429, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI48994962, Length=148, Percent_Identity=28.3783783783784, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=151, Percent_Identity=23.841059602649, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788706, Length=139, Percent_Identity=33.0935251798561, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34471; Mature: 34471

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQASECFSSHVSFCVMNAPEPHPMTVMLDPDQLRTFVAIAETGSFTRAAEVVHKTQSAV
CCHHHHHHHHHHCEEEECCCCCCCEEEEECHHHHHHHHEEECCCCHHHHHHHHHHHHHHH
SMQMKRLEERVGRPVFMRDGRASRLTEDGERLLDYARRIVKLNVEAVLSFADAALSGRVC
HHHHHHHHHHHCCCEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LGVPDDYADRYLPDIMARFSRTHPSVELTVLCEPSSELVQHIAGGTIDLAIITATEITAR
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCCEEEEEEEEEEHHCCC
NAHVIRRERLLWVSSARHSVHLETPVPLALGRTTCQWRDIAVSRLVGAGRSHRILYTSPN
CHHHHHHHHHHEEECCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
SGAVAAAVLAGLAVSVLPESALRTGMRVLGSADGYPPLPPCDIGLLRNRHEPSLLADALA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHH
QHIVQGLDNLTDAEAAQ
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNQASECFSSHVSFCVMNAPEPHPMTVMLDPDQLRTFVAIAETGSFTRAAEVVHKTQSAV
CCHHHHHHHHHHCEEEECCCCCCCEEEEECHHHHHHHHEEECCCCHHHHHHHHHHHHHHH
SMQMKRLEERVGRPVFMRDGRASRLTEDGERLLDYARRIVKLNVEAVLSFADAALSGRVC
HHHHHHHHHHHCCCEEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LGVPDDYADRYLPDIMARFSRTHPSVELTVLCEPSSELVQHIAGGTIDLAIITATEITAR
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCCEEEEEEEEEEHHCCC
NAHVIRRERLLWVSSARHSVHLETPVPLALGRTTCQWRDIAVSRLVGAGRSHRILYTSPN
CHHHHHHHHHHEEECCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
SGAVAAAVLAGLAVSVLPESALRTGMRVLGSADGYPPLPPCDIGLLRNRHEPSLLADALA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHH
QHIVQGLDNLTDAEAAQ
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]