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The map label for this gene is ybdL [H]

Identifier: 154248477

GI number: 154248477

Start: 5037712

End: 5038908

Strand: Reverse

Name: ybdL [H]

Synonym: Xaut_4557

Alternate gene names: 154248477

Gene position: 5038908-5037712 (Counterclockwise)

Preceding gene: 154248478

Following gene: 154248476

Centisome position: 94.91

GC content: 67.75

Gene sequence:

>1197_bases
ATGTCCCTTCTTTCCTCCCCGTCCGCCCGCCCCGCCCGTTCGCTCAATCCCCTGTATGCGGAGCTGCCCACCACCATCTT
CGAGGTGATGTCGCAGCTCGCCCGTACCCATGAGGCGGTCAATCTTGGCCAGGGCTTCCCGGACGATCCTGGCCCGGAGG
ATGTGCGGCGCAAGGCGGCCGACGCGGTGGTGAACGGCTGGAACCAATATCCCCCCATGATGGGCCTGCCGGAGCTGCGT
GCCGCCGCAGCCGCCCATTATCGCCATTGGCAGGAGCTGGAGCTGGATCCCGACGCCGAGGTGATGGTGACATCCGGCGC
CACCGAGGCGCTGGCCGGCGCGCTCCTCGCCCTCATCGAACCCGGCGACGAGGTGGTGCTGTTCCAGCCGCTCTATGACG
CCTATCTGCCATTGGTGAAGCGGGCCGGCGGCATCCCCCGGCTGGTGCGGCTCGAGCCGCCGTCCTGGAGCATCACGCGG
GAGGCGCTGACGGCCGCCTTCTCCGAGCGCACCAAGCTGGTGCTGTTCAACAATCCGCAGAACCCCACCGGCGTCGTCTA
CAGCCGCGCGGATCTCGCCTTGCTGGCCGAATTCTGCGTGGCGTTCGACGCCTATGCGGTGTGCGACGAGGTGTGGGAGC
ACGTGATCTTCGACGGCGTCGCCTTCACCTCGCTCATGGCCCTGCCGGGCATGCGCGAGCGCACGGTGAAGATTTCCTCC
GCCGGCAAGATCTTCGGTATGACCGGCTGGAAGGTCGGGCTCGTCTTCGCCGCCCCGCCCCTGATGAAGGTATTGTCGAA
GGCGCACCAGTTCCTCACCTTCACCACGCCGCCCAATCTGCAGGTGGCGGTGGCCTACGGGCTCGGCAAGGCGGACGATT
ATTTCACCGGCATGCGGGCCGACCTCCAGCGCTCCCGCGACCGGCTGGCGCAGGGGCTCGCGGGCCTCGGCTTTTCGGTG
CTGCCCTCCGCTGGCACCTATTTCCTCTCCATCGACCTTGCCGCCCACACCAATGCCGCGGACGACGAGGCCTTCTGCCT
CGATCTGGTGCGTACCCACGGGGTCGCGACCATCCCGGTCTCGGCCTTCTATGCGCAGGACGCGGTGAAGAGCGTGGTGC
GCTTCTGCTTCGCCAAGCGCGACGAGACCATCGACCGCGCGCTGGAGCGGCTGGCCAAGGTGCCGCTGCTGCGCTGA

Upstream 100 bases:

>100_bases
GCCGCTGATGGCCGGGGAGGCCGCGGTCTCCACCGGACTTTCGCCCCACGGCGAGAAGGTCTAAACGGCCAGAGCGTTTT
CCCCTTGCCGTGACCGTTCC

Downstream 100 bases:

>100_bases
AGCTGGCGCGGGATCACGACTGCGTCATGGGGCCATGGCATGCCGGGCGCGGATCTGACCAATCCTTAATTGGACCCAAA
GATCGATTTAGTGTTGCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSLLSSPSARPARSLNPLYAELPTTIFEVMSQLARTHEAVNLGQGFPDDPGPEDVRRKAADAVVNGWNQYPPMMGLPELR
AAAAAHYRHWQELELDPDAEVMVTSGATEALAGALLALIEPGDEVVLFQPLYDAYLPLVKRAGGIPRLVRLEPPSWSITR
EALTAAFSERTKLVLFNNPQNPTGVVYSRADLALLAEFCVAFDAYAVCDEVWEHVIFDGVAFTSLMALPGMRERTVKISS
AGKIFGMTGWKVGLVFAAPPLMKVLSKAHQFLTFTTPPNLQVAVAYGLGKADDYFTGMRADLQRSRDRLAQGLAGLGFSV
LPSAGTYFLSIDLAAHTNAADDEAFCLDLVRTHGVATIPVSAFYAQDAVKSVVRFCFAKRDETIDRALERLAKVPLLR

Sequences:

>Translated_398_residues
MSLLSSPSARPARSLNPLYAELPTTIFEVMSQLARTHEAVNLGQGFPDDPGPEDVRRKAADAVVNGWNQYPPMMGLPELR
AAAAAHYRHWQELELDPDAEVMVTSGATEALAGALLALIEPGDEVVLFQPLYDAYLPLVKRAGGIPRLVRLEPPSWSITR
EALTAAFSERTKLVLFNNPQNPTGVVYSRADLALLAEFCVAFDAYAVCDEVWEHVIFDGVAFTSLMALPGMRERTVKISS
AGKIFGMTGWKVGLVFAAPPLMKVLSKAHQFLTFTTPPNLQVAVAYGLGKADDYFTGMRADLQRSRDRLAQGLAGLGFSV
LPSAGTYFLSIDLAAHTNAADDEAFCLDLVRTHGVATIPVSAFYAQDAVKSVVRFCFAKRDETIDRALERLAKVPLLR
>Mature_397_residues
SLLSSPSARPARSLNPLYAELPTTIFEVMSQLARTHEAVNLGQGFPDDPGPEDVRRKAADAVVNGWNQYPPMMGLPELRA
AAAAHYRHWQELELDPDAEVMVTSGATEALAGALLALIEPGDEVVLFQPLYDAYLPLVKRAGGIPRLVRLEPPSWSITRE
ALTAAFSERTKLVLFNNPQNPTGVVYSRADLALLAEFCVAFDAYAVCDEVWEHVIFDGVAFTSLMALPGMRERTVKISSA
GKIFGMTGWKVGLVFAAPPLMKVLSKAHQFLTFTTPPNLQVAVAYGLGKADDYFTGMRADLQRSRDRLAQGLAGLGFSVL
PSAGTYFLSIDLAAHTNAADDEAFCLDLVRTHGVATIPVSAFYAQDAVKSVVRFCFAKRDETIDRALERLAKVPLLR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=35.8585858585859, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=35.8585858585859, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=32.7455919395466, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=32.7455919395466, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=30.7888040712468, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI4507369, Length=393, Percent_Identity=24.9363867684478, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786816, Length=374, Percent_Identity=40.3743315508021, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1788722, Length=326, Percent_Identity=25.7668711656442, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788627, Length=308, Percent_Identity=23.0519480519481, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=432, Percent_Identity=34.7222222222222, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71994476, Length=427, Percent_Identity=34.8946135831382, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17567369, Length=417, Percent_Identity=30.9352517985612, Blast_Score=188, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322401, Length=385, Percent_Identity=31.4285714285714, Blast_Score=183, Evalue=4e-47,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=34.4387755102041, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=34.4387755102041, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=34.4387755102041, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=34.4387755102041, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI18859735, Length=340, Percent_Identity=25.5882352941176, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43354; Mature: 43223

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLSSPSARPARSLNPLYAELPTTIFEVMSQLARTHEAVNLGQGFPDDPGPEDVRRKAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
DAVVNGWNQYPPMMGLPELRAAAAAHYRHWQELELDPDAEVMVTSGATEALAGALLALIE
HHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCC
PGDEVVLFQPLYDAYLPLVKRAGGIPRLVRLEPPSWSITREALTAAFSERTKLVLFNNPQ
CCCCEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCC
NPTGVVYSRADLALLAEFCVAFDAYAVCDEVWEHVIFDGVAFTSLMALPGMRERTVKISS
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEC
AGKIFGMTGWKVGLVFAAPPLMKVLSKAHQFLTFTTPPNLQVAVAYGLGKADDYFTGMRA
CCCEEEECCCEEEEEEECCHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHH
DLQRSRDRLAQGLAGLGFSVLPSAGTYFLSIDLAAHTNAADDEAFCLDLVRTHGVATIPV
HHHHHHHHHHHHHHHCCCHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEH
SAFYAQDAVKSVVRFCFAKRDETIDRALERLAKVPLLR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLLSSPSARPARSLNPLYAELPTTIFEVMSQLARTHEAVNLGQGFPDDPGPEDVRRKAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
DAVVNGWNQYPPMMGLPELRAAAAAHYRHWQELELDPDAEVMVTSGATEALAGALLALIE
HHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCC
PGDEVVLFQPLYDAYLPLVKRAGGIPRLVRLEPPSWSITREALTAAFSERTKLVLFNNPQ
CCCCEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCC
NPTGVVYSRADLALLAEFCVAFDAYAVCDEVWEHVIFDGVAFTSLMALPGMRERTVKISS
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEC
AGKIFGMTGWKVGLVFAAPPLMKVLSKAHQFLTFTTPPNLQVAVAYGLGKADDYFTGMRA
CCCEEEECCCEEEEEEECCHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHH
DLQRSRDRLAQGLAGLGFSVLPSAGTYFLSIDLAAHTNAADDEAFCLDLVRTHGVATIPV
HHHHHHHHHHHHHHHCCCHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEH
SAFYAQDAVKSVVRFCFAKRDETIDRALERLAKVPLLR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]