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The map label for this gene is ybeC [H]

Identifier: 154248392

GI number: 154248392

Start: 4963880

End: 4965481

Strand: Reverse

Name: ybeC [H]

Synonym: Xaut_4472

Alternate gene names: 154248392

Gene position: 4965481-4963880 (Counterclockwise)

Preceding gene: 154248393

Following gene: 154248390

Centisome position: 93.53

GC content: 69.91

Gene sequence:

>1602_bases
ATGGGCAAGCTGAAGCGCGAGATCGGGCTGATCGGCCTCACCTTCGTGGCCGTGAGCGGCATCATCGGCTCCGGCTGGCT
GTTCGCGCCGCTGCTGGCCGCCCAGCATGCCGGCCCCGCCGCCCTGATCGCGTGGGTGATCGGCGGTGCCGCCATGCTGC
TGTTCGCCCTGACCTTCGCGGAAATCTCGGCGATGCTGCCGGTGGCCGGCGGCATCGCGCGGGTTCCCCAGTTCAGCCAC
GGCAATGTGGTGGCCATGGCCATGGGGTGGAGCGCCTGGGTGGGCTACAACACCACCGCCCCCATCGAGGTGGAGGCCAT
GCTGCGCTACCTCGGCCCCCATCTGGGCTGGCTCTATACGGCGCCGGGCAGCGGCACACTGTCGTGGGCGGGGGTGGCGG
TAGCGGGGCTGATGATGGTCGCCTTCACCGTCATCAATGCCTTCGGCGTGCGCTTCTTCACCCGCGTGAACACCGCCATA
ACCTGGCTCAAGATCGCCATTCCCCTCGTGGTCGTCGCGGCGCTGCTGGCGGCGCGGTTCGAGCCGGCCAATTTCACGCA
AGCGGGCGGCGGGTTCGCGCCGTTCGGGGTGGCCGGCGTGCTGGCGGCGGTCTCGTCCGGGGGCATCGCCTTTTCCTTCA
TCGGCTTTCGCCATGCCATCGACATGGCGGGAGAGGTGAAGAACCCCGGCGTCACCATTCCCATCGCCCTCGTGCTGGCG
CTGGCCATCGCCTTCGTGGTCTATGGCGGCATCCAGTTCGCTTTCACCGGCGCGCTGCTGCAGGCGGATCTTGCCCACGG
CTGGGGAGCGCTGGCGCTGCCGGGGGATTTCGGGCCGCTGGGCGCGCTCGCCGCGGCGCTGGGGATGCTGTGGCTGGTGA
GCCTTTTGAACTTCGGCGCGGTGGTGGGACCGTTCGCCGGCGGCCTCGTCTCGGTGGGCTCCAACGCACGCCTCGCCTTC
GCGCTGGCGGAGAACGGCTTTTTTCCCGAGCGCTTCGCCTCGCTCTCGGCGCGGGGCGTGCCGGTGGCCGCGCTGTTGCT
CAACCTCGTGTTCTCGCTGGCCACCTTCGTGCTCTTGCCGTTCAGCGAGGTGGTGCAGCTGAACTCTTCAGCCGTCATCC
TCTCCTTCGTGGTGGGGCCGGTGGCGGTGGTGGCCCTGCGCCAGCTGCTGCCCGACGCGACGCGGCCGCTGCGGGTGCCG
GCGGTGAAGCTGGTGGCACCGGTGGCCTTCATCATCGCCACTTACATCATCTACTGGAGCGGATGGCCCACCGTGTGGCG
CCTGGGCCTGTGCCTGCTGGCGGGTCTGGCGCTGTTCCTCGTCCATGCCCGCAATCGTGCCGCCGGCAGCCTGGATCTGG
CGGAAGCGGTGTGGCTCGCGCCCTACCTCGCTGGGCTCGGGCTGGTGTCGTTCCTCGGCAGCTTCGGCGGCCGGGGCCTC
ATCCCCTTCGGCTGGGACCTGCTGGTGCTGGCTGCGCTCGGGGGCGGGGCGTTCGCGCTGGCGGTGCGTGAGCGGCTGAG
CCAGGCCAAGTTTGACCGCTACATGAGCGAGGAGCGGGTCCTGGACGCGGCCACGGAGGAAGAGCCGGAGGTCCGGGTCT
AG

Upstream 100 bases:

>100_bases
AAACACGCGGGTACCGCGCGCGACAAGGTGCATGCGGCAGCGGTTCAGCTTAGTCTTCCGTATAGCCGGGGCCTGAAAGC
CGGTGCGGGCGGGGGAATCG

Downstream 100 bases:

>100_bases
TCGGATCTTCTCGCAAAAACGGCCGACCCACAGGGCCGGCCGTTCAGGAAAGCTGGGACGGCGGAAGGATTGCCCTCAGG
CGGCGCTGTCCTTGCTGTCC

Product: amino acid permease-associated protein

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MGKLKREIGLIGLTFVAVSGIIGSGWLFAPLLAAQHAGPAALIAWVIGGAAMLLFALTFAEISAMLPVAGGIARVPQFSH
GNVVAMAMGWSAWVGYNTTAPIEVEAMLRYLGPHLGWLYTAPGSGTLSWAGVAVAGLMMVAFTVINAFGVRFFTRVNTAI
TWLKIAIPLVVVAALLAARFEPANFTQAGGGFAPFGVAGVLAAVSSGGIAFSFIGFRHAIDMAGEVKNPGVTIPIALVLA
LAIAFVVYGGIQFAFTGALLQADLAHGWGALALPGDFGPLGALAAALGMLWLVSLLNFGAVVGPFAGGLVSVGSNARLAF
ALAENGFFPERFASLSARGVPVAALLLNLVFSLATFVLLPFSEVVQLNSSAVILSFVVGPVAVVALRQLLPDATRPLRVP
AVKLVAPVAFIIATYIIYWSGWPTVWRLGLCLLAGLALFLVHARNRAAGSLDLAEAVWLAPYLAGLGLVSFLGSFGGRGL
IPFGWDLLVLAALGGGAFALAVRERLSQAKFDRYMSEERVLDAATEEEPEVRV

Sequences:

>Translated_533_residues
MGKLKREIGLIGLTFVAVSGIIGSGWLFAPLLAAQHAGPAALIAWVIGGAAMLLFALTFAEISAMLPVAGGIARVPQFSH
GNVVAMAMGWSAWVGYNTTAPIEVEAMLRYLGPHLGWLYTAPGSGTLSWAGVAVAGLMMVAFTVINAFGVRFFTRVNTAI
TWLKIAIPLVVVAALLAARFEPANFTQAGGGFAPFGVAGVLAAVSSGGIAFSFIGFRHAIDMAGEVKNPGVTIPIALVLA
LAIAFVVYGGIQFAFTGALLQADLAHGWGALALPGDFGPLGALAAALGMLWLVSLLNFGAVVGPFAGGLVSVGSNARLAF
ALAENGFFPERFASLSARGVPVAALLLNLVFSLATFVLLPFSEVVQLNSSAVILSFVVGPVAVVALRQLLPDATRPLRVP
AVKLVAPVAFIIATYIIYWSGWPTVWRLGLCLLAGLALFLVHARNRAAGSLDLAEAVWLAPYLAGLGLVSFLGSFGGRGL
IPFGWDLLVLAALGGGAFALAVRERLSQAKFDRYMSEERVLDAATEEEPEVRV
>Mature_532_residues
GKLKREIGLIGLTFVAVSGIIGSGWLFAPLLAAQHAGPAALIAWVIGGAAMLLFALTFAEISAMLPVAGGIARVPQFSHG
NVVAMAMGWSAWVGYNTTAPIEVEAMLRYLGPHLGWLYTAPGSGTLSWAGVAVAGLMMVAFTVINAFGVRFFTRVNTAIT
WLKIAIPLVVVAALLAARFEPANFTQAGGGFAPFGVAGVLAAVSSGGIAFSFIGFRHAIDMAGEVKNPGVTIPIALVLAL
AIAFVVYGGIQFAFTGALLQADLAHGWGALALPGDFGPLGALAAALGMLWLVSLLNFGAVVGPFAGGLVSVGSNARLAFA
LAENGFFPERFASLSARGVPVAALLLNLVFSLATFVLLPFSEVVQLNSSAVILSFVVGPVAVVALRQLLPDATRPLRVPA
VKLVAPVAFIIATYIIYWSGWPTVWRLGLCLLAGLALFLVHARNRAAGSLDLAEAVWLAPYLAGLGLVSFLGSFGGRGLI
PFGWDLLVLAALGGGAFALAVRERLSQAKFDRYMSEERVLDAATEEEPEVRV

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=467, Percent_Identity=24.6252676659529, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI181337167, Length=402, Percent_Identity=23.8805970149254, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI110347453, Length=365, Percent_Identity=27.6712328767123, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4507047, Length=421, Percent_Identity=24.4655581947743, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI258645169, Length=420, Percent_Identity=24.047619047619, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1786302, Length=416, Percent_Identity=26.2019230769231, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786602, Length=421, Percent_Identity=24.2280285035629, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788480, Length=356, Percent_Identity=24.438202247191, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=413, Percent_Identity=25.181598062954, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17532491, Length=408, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566699, Length=390, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=412, Percent_Identity=24.0291262135922, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667468, Length=410, Percent_Identity=25.8536585365854, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221512776, Length=425, Percent_Identity=24.7058823529412, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666159, Length=424, Percent_Identity=25, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=24.4755244755245, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=24.4755244755245, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=24.4755244755245, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221331183, Length=483, Percent_Identity=24.6376811594203, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647653, Length=483, Percent_Identity=24.6376811594203, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24664379, Length=483, Percent_Identity=24.6376811594203, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281366235, Length=405, Percent_Identity=26.9135802469136, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI116007820, Length=405, Percent_Identity=26.9135802469136, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 55379; Mature: 55248

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLKREIGLIGLTFVAVSGIIGSGWLFAPLLAAQHAGPAALIAWVIGGAAMLLFALTFA
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
EISAMLPVAGGIARVPQFSHGNVVAMAMGWSAWVGYNTTAPIEVEAMLRYLGPHLGWLYT
HHHHHHHHCCCHHHCCCCCCCCEEEEEECCHHHCCCCCCCCHHHHHHHHHHCCCCCEEEE
APGSGTLSWAGVAVAGLMMVAFTVINAFGVRFFTRVNTAITWLKIAIPLVVVAALLAARF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPANFTQAGGGFAPFGVAGVLAAVSSGGIAFSFIGFRHAIDMAGEVKNPGVTIPIALVLA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LAIAFVVYGGIQFAFTGALLQADLAHGWGALALPGDFGPLGALAAALGMLWLVSLLNFGA
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
VVGPFAGGLVSVGSNARLAFALAENGFFPERFASLSARGVPVAALLLNLVFSLATFVLLP
HHHHHCCCHHCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
FSEVVQLNSSAVILSFVVGPVAVVALRQLLPDATRPLRVPAVKLVAPVAFIIATYIIYWS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GWPTVWRLGLCLLAGLALFLVHARNRAAGSLDLAEAVWLAPYLAGLGLVSFLGSFGGRGL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IPFGWDLLVLAALGGGAFALAVRERLSQAKFDRYMSEERVLDAATEEEPEVRV
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GKLKREIGLIGLTFVAVSGIIGSGWLFAPLLAAQHAGPAALIAWVIGGAAMLLFALTFA
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH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CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]