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The map label for this gene is ntrY [H]

Identifier: 154248318

GI number: 154248318

Start: 4875926

End: 4878163

Strand: Reverse

Name: ntrY [H]

Synonym: Xaut_4398

Alternate gene names: 154248318

Gene position: 4878163-4875926 (Counterclockwise)

Preceding gene: 154248319

Following gene: 154248317

Centisome position: 91.89

GC content: 68.63

Gene sequence:

>2238_bases
ATGACGGACGCGCCGGTCAAGGACGCAGTGGAAGGCGTTGTGCCCCGTCGCGGCATTGCCGCCCGCCTGTTCGCGCCCAT
CATTGTGGTCCTGTCGCTGGTGCTGGCGGTCGCCACCTTCCTGATCCTGATGGGCCTCACCTCCATCGTGCCGACGCCGC
AGGTGGTGGTGGGCGTGCTCACCGCATCGGGCATCGCGGTGCTCATCCTGCTGGCCATCATCGGCCGGGAGGTGTGGCGC
ATCCTGCGGGCACGGGCGCGCGGGCGGGCCGCCTCGCGGCTGCATGTGCGCATCGTCGGCCTGTTCGCGGGCGTGGCGGT
GGTGCCGGCCATCGTGGTGGCGCTGGTGGCCAGCCTCACCCTCGACCGCAGCCTTGATCGCTACTTCTCCGGCCGGACCC
GGGAGATCGTCGGCACCGCCGCTTCGGTGGCGCAGACCTATGTGCGCGAGCACGCGCTCTCCATCCGCGGCGACGTGCTC
GCCATGAGCAATGACCTGTCGCGGATGAAGCAGCTCTACGACACGGATATCGAGAAGTTCCGGCAGATCCTCACCGCCCA
GGCGGCGCTGCGCAACGTGCCGGGCGCACAGATCGTCCGGCGCGACCTCTCGGTGGTGGAGCGGGCGAACCTGCGGACGG
ACCGCGAATATATCGTCCCCTCCAACATCGCCATCGCCGAGGCTTCCACCGAGCAGCCCATCATCTATCTGCCGTCGGAC
GCGGACTTCGTGGGCGCGGTGGCGCCGATCGCGGGATTCGACGACCTGTTCCTTTACGTGGCGCGGCCCGTCGACCCGCG
GGTCATCGGCTTTCTCAAGGTGACGCAGGACACCCTTGCCGATTACCGGGCGCTGGAGGAGCGGCGCTTCAACGTGCAGC
TCGCCTTTGCGCTGATGTATTCCATTGTCACGCTCATCGTGCTGCTGTCGGCGGTCTGGCTCGGGATCAACTTCTCCAAA
TGGCTGGTATCGCCCATCCGGCGGCTCATGTGGGCGGCGGGACGGGTGGCGGCGGGCAATCTGGAAGTGCAGGTGCCGGT
CAACCGGGCCGAGGGCGACCTCGCGACCCTGGGCGAAACCTTCAACAAGATGACGGTCGAGCTGAAGACCCAGCGCAACG
CGTTGGTGACGGCGCGCGACCAGATGGACAGCCGTCGCCGCTTCACCGAGGCGGTGCTCTCCGGCGTCGGCGCGGGCGTC
ATCGGCATCGATGCCGAGGCGCAGGTCACCATCCTCAACCGCTCCGCCGAGAAGCTCCTGGGCCTGAGCGAGGACGAGGC
GCTCGGCCGCAAGCTCGCGGATGTGGTGCCGGAAACCGACGCCCTGGTGGCCGAGGCCATGGGCGCGGGCCAGCGCGCGG
TACAGGGCAACATCACCATCCAGCGGGACGGCCGGGAACGGATTTTCGCCGTCCGGGTCACCACCGAGCAGTCCACGGCC
GAGGATCACGGCTGGGTGGTGACGCTGGACGACATCACCGCCCTGGTCTCGGCCCAGCGCACCTCCGCCTGGGCTGACGT
GGCCCGGCGCATCGCCCACGAGATCAAGAACCCGCTGACCCCCATCCAGCTCTCCGCCGAGCGGCTGAAGCGCAAGTACG
GGCGCCACATCACCCAGGATCGCGACGTGTTCGACCAGTGCACCGACACCATCATCCGTCAGGTCGGCGACATCGGCCGG
ATGGTGGACGAGTTCTCCTCCTTCGCCCGCATGCCCAAGCCCGTGGTAGATGCGCAGGACCTTGCCGAGACCGTGCGCCA
GGGCGTGTTCCTCATGCGCGTCGGCCATCCTGACGTGACCTTCGAGACCGAGCTGCCGCCCTCCATGCCGGCGCGGTTCG
ACCGGCGCCTGATCTCCCAGGCGCTCACCAACATCCTCAAGAACGCCGCCGAGGCCATCGAGGGGGTGCCTGAGGCCGAG
CGCGGCAAGGGCCTCATCCGCGTGCGCGTGGTTGCGGAGGGCGAGGACCGCGTCATCGACGTCATCGACAACGGCGCCGG
ACTGCCGAAGGAAAAGCGCAGCCGGCTGCTGGAGCCGTATGTGACCACCCGCGAGAAGGGCACCGGGCTCGGCCTCGCCA
TCGTGGGGAAAATCATGGAAGAGCACGGCGGCTTCATCGAACTCAACGATTCCCCCGAGGGCCGGGGGGCCTGGATCCGG
CTTCGGATGCGGGCAGACGGTCAACCACCGGCCGGCGCGGGCGGGGCGCAACCGGTCCCTGAAACAGGGAGGGCCTGA

Upstream 100 bases:

>100_bases
CCTCTGTCACATTTTTGCACCAGTGTCGTTCCACTGCATCACCCCTGTCGCGTGACTCGGCTCGCGACAGGGGGCGGAAG
CCTGGGGGACTGTGGCAAGG

Downstream 100 bases:

>100_bases
CACATGGCCATGGACATTCTCATCGTGGACGATGAGGCCGACATCTGCGAACTGGTGGCCGGCATCCTGGAGGACGAGGG
CTATGCCGCCCGCACCGCCC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 745; Mature: 744

Protein sequence:

>745_residues
MTDAPVKDAVEGVVPRRGIAARLFAPIIVVLSLVLAVATFLILMGLTSIVPTPQVVVGVLTASGIAVLILLAIIGREVWR
ILRARARGRAASRLHVRIVGLFAGVAVVPAIVVALVASLTLDRSLDRYFSGRTREIVGTAASVAQTYVREHALSIRGDVL
AMSNDLSRMKQLYDTDIEKFRQILTAQAALRNVPGAQIVRRDLSVVERANLRTDREYIVPSNIAIAEASTEQPIIYLPSD
ADFVGAVAPIAGFDDLFLYVARPVDPRVIGFLKVTQDTLADYRALEERRFNVQLAFALMYSIVTLIVLLSAVWLGINFSK
WLVSPIRRLMWAAGRVAAGNLEVQVPVNRAEGDLATLGETFNKMTVELKTQRNALVTARDQMDSRRRFTEAVLSGVGAGV
IGIDAEAQVTILNRSAEKLLGLSEDEALGRKLADVVPETDALVAEAMGAGQRAVQGNITIQRDGRERIFAVRVTTEQSTA
EDHGWVVTLDDITALVSAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRHITQDRDVFDQCTDTIIRQVGDIGR
MVDEFSSFARMPKPVVDAQDLAETVRQGVFLMRVGHPDVTFETELPPSMPARFDRRLISQALTNILKNAAEAIEGVPEAE
RGKGLIRVRVVAEGEDRVIDVIDNGAGLPKEKRSRLLEPYVTTREKGTGLGLAIVGKIMEEHGGFIELNDSPEGRGAWIR
LRMRADGQPPAGAGGAQPVPETGRA

Sequences:

>Translated_745_residues
MTDAPVKDAVEGVVPRRGIAARLFAPIIVVLSLVLAVATFLILMGLTSIVPTPQVVVGVLTASGIAVLILLAIIGREVWR
ILRARARGRAASRLHVRIVGLFAGVAVVPAIVVALVASLTLDRSLDRYFSGRTREIVGTAASVAQTYVREHALSIRGDVL
AMSNDLSRMKQLYDTDIEKFRQILTAQAALRNVPGAQIVRRDLSVVERANLRTDREYIVPSNIAIAEASTEQPIIYLPSD
ADFVGAVAPIAGFDDLFLYVARPVDPRVIGFLKVTQDTLADYRALEERRFNVQLAFALMYSIVTLIVLLSAVWLGINFSK
WLVSPIRRLMWAAGRVAAGNLEVQVPVNRAEGDLATLGETFNKMTVELKTQRNALVTARDQMDSRRRFTEAVLSGVGAGV
IGIDAEAQVTILNRSAEKLLGLSEDEALGRKLADVVPETDALVAEAMGAGQRAVQGNITIQRDGRERIFAVRVTTEQSTA
EDHGWVVTLDDITALVSAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRHITQDRDVFDQCTDTIIRQVGDIGR
MVDEFSSFARMPKPVVDAQDLAETVRQGVFLMRVGHPDVTFETELPPSMPARFDRRLISQALTNILKNAAEAIEGVPEAE
RGKGLIRVRVVAEGEDRVIDVIDNGAGLPKEKRSRLLEPYVTTREKGTGLGLAIVGKIMEEHGGFIELNDSPEGRGAWIR
LRMRADGQPPAGAGGAQPVPETGRA
>Mature_744_residues
TDAPVKDAVEGVVPRRGIAARLFAPIIVVLSLVLAVATFLILMGLTSIVPTPQVVVGVLTASGIAVLILLAIIGREVWRI
LRARARGRAASRLHVRIVGLFAGVAVVPAIVVALVASLTLDRSLDRYFSGRTREIVGTAASVAQTYVREHALSIRGDVLA
MSNDLSRMKQLYDTDIEKFRQILTAQAALRNVPGAQIVRRDLSVVERANLRTDREYIVPSNIAIAEASTEQPIIYLPSDA
DFVGAVAPIAGFDDLFLYVARPVDPRVIGFLKVTQDTLADYRALEERRFNVQLAFALMYSIVTLIVLLSAVWLGINFSKW
LVSPIRRLMWAAGRVAAGNLEVQVPVNRAEGDLATLGETFNKMTVELKTQRNALVTARDQMDSRRRFTEAVLSGVGAGVI
GIDAEAQVTILNRSAEKLLGLSEDEALGRKLADVVPETDALVAEAMGAGQRAVQGNITIQRDGRERIFAVRVTTEQSTAE
DHGWVVTLDDITALVSAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRHITQDRDVFDQCTDTIIRQVGDIGRM
VDEFSSFARMPKPVVDAQDLAETVRQGVFLMRVGHPDVTFETELPPSMPARFDRRLISQALTNILKNAAEAIEGVPEAER
GKGLIRVRVVAEGEDRVIDVIDNGAGLPKEKRSRLLEPYVTTREKGTGLGLAIVGKIMEEHGGFIELNDSPEGRGAWIRL
RMRADGQPPAGAGGAQPVPETGRA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=351, Percent_Identity=27.0655270655271, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790300, Length=346, Percent_Identity=28.3236994219653, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=29.1304347826087, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789808, Length=209, Percent_Identity=29.1866028708134, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81245; Mature: 81114

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAPVKDAVEGVVPRRGIAARLFAPIIVVLSLVLAVATFLILMGLTSIVPTPQVVVGVL
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TASGIAVLILLAIIGREVWRILRARARGRAASRLHVRIVGLFAGVAVVPAIVVALVASLT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRSLDRYFSGRTREIVGTAASVAQTYVREHALSIRGDVLAMSNDLSRMKQLYDTDIEKF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
RQILTAQAALRNVPGAQIVRRDLSVVERANLRTDREYIVPSNIAIAEASTEQPIIYLPSD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEECCCCCCEEECCCC
ADFVGAVAPIAGFDDLFLYVARPVDPRVIGFLKVTQDTLADYRALEERRFNVQLAFALMY
CCHHHHHHHHCCHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SIVTLIVLLSAVWLGINFSKWLVSPIRRLMWAAGRVAAGNLEVQVPVNRAEGDLATLGET
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCEEEEEECCCCCCHHHHHHHH
FNKMTVELKTQRNALVTARDQMDSRRRFTEAVLSGVGAGVIGIDAEAQVTILNRSAEKLL
HHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHC
GLSEDEALGRKLADVVPETDALVAEAMGAGQRAVQGNITIQRDGRERIFAVRVTTEQSTA
CCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCEEEEECCCCEEEEEEEECCCCCC
EDHGWVVTLDDITALVSAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRHITQD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
RDVFDQCTDTIIRQVGDIGRMVDEFSSFARMPKPVVDAQDLAETVRQGVFLMRVGHPDVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEECCCCCE
FETELPPSMPARFDRRLISQALTNILKNAAEAIEGVPEAERGKGLIRVRVVAEGEDRVID
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEECCCCCEEE
VIDNGAGLPKEKRSRLLEPYVTTREKGTGLGLAIVGKIMEEHGGFIELNDSPEGRGAWIR
EECCCCCCCHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEE
LRMRADGQPPAGAGGAQPVPETGRA
EEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDAPVKDAVEGVVPRRGIAARLFAPIIVVLSLVLAVATFLILMGLTSIVPTPQVVVGVL
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TASGIAVLILLAIIGREVWRILRARARGRAASRLHVRIVGLFAGVAVVPAIVVALVASLT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRSLDRYFSGRTREIVGTAASVAQTYVREHALSIRGDVLAMSNDLSRMKQLYDTDIEKF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
RQILTAQAALRNVPGAQIVRRDLSVVERANLRTDREYIVPSNIAIAEASTEQPIIYLPSD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEECCCCCCEEECCCC
ADFVGAVAPIAGFDDLFLYVARPVDPRVIGFLKVTQDTLADYRALEERRFNVQLAFALMY
CCHHHHHHHHCCHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SIVTLIVLLSAVWLGINFSKWLVSPIRRLMWAAGRVAAGNLEVQVPVNRAEGDLATLGET
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCEEEEEECCCCCCHHHHHHHH
FNKMTVELKTQRNALVTARDQMDSRRRFTEAVLSGVGAGVIGIDAEAQVTILNRSAEKLL
HHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHC
GLSEDEALGRKLADVVPETDALVAEAMGAGQRAVQGNITIQRDGRERIFAVRVTTEQSTA
CCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCEEEEECCCCEEEEEEEECCCCCC
EDHGWVVTLDDITALVSAQRTSAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRHITQD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
RDVFDQCTDTIIRQVGDIGRMVDEFSSFARMPKPVVDAQDLAETVRQGVFLMRVGHPDVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEECCCCCE
FETELPPSMPARFDRRLISQALTNILKNAAEAIEGVPEAERGKGLIRVRVVAEGEDRVID
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEECCCCCEEE
VIDNGAGLPKEKRSRLLEPYVTTREKGTGLGLAIVGKIMEEHGGFIELNDSPEGRGAWIR
EECCCCCCCHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEE
LRMRADGQPPAGAGGAQPVPETGRA
EEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]