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The map label for this gene is trkA

Identifier: 154248316

GI number: 154248316

Start: 4873061

End: 4874437

Strand: Reverse

Name: trkA

Synonym: Xaut_4396

Alternate gene names: 154248316

Gene position: 4874437-4873061 (Counterclockwise)

Preceding gene: 154248317

Following gene: 154248315

Centisome position: 91.82

GC content: 68.48

Gene sequence:

>1377_bases
ATGAAGGTCGTGATCTGCGGCGCGGGCCAGGTGGGGTTCGGCATTGCCGAGCGCCTCGCCGGTGAGCAGAACGACGTGTC
CATCATCGACACGAGCCCGCGGCGCATCCAGATGGTGACCGAGCAGCTGGACGTGCGCGGCGTGGTGGGGCAGGGCTCCC
ATCCGGACGTGCTGGCGCGCGCCGGGGTCGAGGCCGCCGACATGCTCATCGCGGTGACCCTCCACGACGAGGTGAACATG
GTGGCCTGCCAGGTGGGCCACGCCTTGTTCAACGTGCCCACCAAGGTCGCCCGCATCCGCGCCCAGACCTATCTGGCGCC
GGAATGGCGCGACCTATTCTCCCGCGACCAGCTGCCCATCGACGTCATCATCTCCCCCGAGATCGAGGTCGGCGAGATGG
TGCTGCGCCGCCTGTCGCTGCCCGGGGCCACCGATACGGTGAGCTTCTCCGACGGGGCGGTGCAGGTGGTGGGCGTGCTG
TGCGGCGAGGACTGCCCGGTGGTGGATACCCCCCTCAGCCAGCTCACCCAGCTTTTCCCGGACATGCCGGCCACCATCGT
GGCCGTGAGCCGGAAGGGCAAGACGCTGGTGCCGCGCTCCAACGACCAGCTGGCGGTGGGCGACATCGTCTATTTCGTCG
CCCAGGCAGACCAGGTGCAGCGCGCCCTGTCCCTGCTCGGGCACGACGAGGTGCCGGGCCAGCGCATCGTCATCGCCGGG
GGCGGCAATATCGGCTATTACGTGGCAAGCGAGCTGGAGCGGCGCAATGCGGCCGCGCGGGTCAAGCTCATCGAATTCTC
GCGCGAGCGCGCCCAGACCATCGCCGAAGTGCTCTCGCGCACGGTGGTGCTGAACGGCGACGCGCTGGAGCGCGCCATCC
TCGACGAGGCCGGGGTGCGCGAGGCGGACACCATGATTTCGCTCACCAATGACGACCGGATCAACATCCTGTCCTGCCTG
CTGGCCAAGCAGATCGGCGCGAAGCGCATCCTGGCGCTGCTGAACGAGCAGGGCTACGCCACCTTCGCCCGGGGCCTGGG
CATCGACGCCCATGTGAATCCGCGCCAGATCACCGTTTCCAAGGTGCTCCAGCATGTGCGGCGCGGGCGCATTCGCGGCG
TCCATGCGCTGCTCGACGGCTCCGGCGAGATGATCGAGGCGGAAGCGCTGGAAACCTCGCCGCTGGTGGGCAAGCCGCTG
AAGGACCTCGACCTTCTGGAGGGGCTGCGCATCGGCGCCATCGTGCGGAACGGACAGGTGCTGCTGCCGCGCGGCGATTT
CGTGGTGCGGGCCCACGACCGGGTGGTGCTGTTCGCCCTCGCCGATCGCATCAAGCGCGTGGAACAGCTGTTCCGCGTGG
CGCTCGAATTCTTCTGA

Upstream 100 bases:

>100_bases
TACCCGAAAAAGGGGCTGCATCTGAGCTGAGGCTCAAGGTGCGATCGGTTTTGCCGCGATCTTTCAGGTCGCGATTCGCC
TGGGCGCCGGGGGAGGGTTC

Downstream 100 bases:

>100_bases
TCCTCTAAGGCCTTTCCGTTTCCCACTTCTCCTGGTCGCCAAGTTCTCCTGCTTGCAAGGCGCATATGGTCAACGCCGCT
CGCCCACTTGCCGCCGGTCT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVVICGAGQVGFGIAERLAGEQNDVSIIDTSPRRIQMVTEQLDVRGVVGQGSHPDVLARAGVEAADMLIAVTLHDEVNM
VACQVGHALFNVPTKVARIRAQTYLAPEWRDLFSRDQLPIDVIISPEIEVGEMVLRRLSLPGATDTVSFSDGAVQVVGVL
CGEDCPVVDTPLSQLTQLFPDMPATIVAVSRKGKTLVPRSNDQLAVGDIVYFVAQADQVQRALSLLGHDEVPGQRIVIAG
GGNIGYYVASELERRNAAARVKLIEFSRERAQTIAEVLSRTVVLNGDALERAILDEAGVREADTMISLTNDDRINILSCL
LAKQIGAKRILALLNEQGYATFARGLGIDAHVNPRQITVSKVLQHVRRGRIRGVHALLDGSGEMIEAEALETSPLVGKPL
KDLDLLEGLRIGAIVRNGQVLLPRGDFVVRAHDRVVLFALADRIKRVEQLFRVALEFF

Sequences:

>Translated_458_residues
MKVVICGAGQVGFGIAERLAGEQNDVSIIDTSPRRIQMVTEQLDVRGVVGQGSHPDVLARAGVEAADMLIAVTLHDEVNM
VACQVGHALFNVPTKVARIRAQTYLAPEWRDLFSRDQLPIDVIISPEIEVGEMVLRRLSLPGATDTVSFSDGAVQVVGVL
CGEDCPVVDTPLSQLTQLFPDMPATIVAVSRKGKTLVPRSNDQLAVGDIVYFVAQADQVQRALSLLGHDEVPGQRIVIAG
GGNIGYYVASELERRNAAARVKLIEFSRERAQTIAEVLSRTVVLNGDALERAILDEAGVREADTMISLTNDDRINILSCL
LAKQIGAKRILALLNEQGYATFARGLGIDAHVNPRQITVSKVLQHVRRGRIRGVHALLDGSGEMIEAEALETSPLVGKPL
KDLDLLEGLRIGAIVRNGQVLLPRGDFVVRAHDRVVLFALADRIKRVEQLFRVALEFF
>Mature_458_residues
MKVVICGAGQVGFGIAERLAGEQNDVSIIDTSPRRIQMVTEQLDVRGVVGQGSHPDVLARAGVEAADMLIAVTLHDEVNM
VACQVGHALFNVPTKVARIRAQTYLAPEWRDLFSRDQLPIDVIISPEIEVGEMVLRRLSLPGATDTVSFSDGAVQVVGVL
CGEDCPVVDTPLSQLTQLFPDMPATIVAVSRKGKTLVPRSNDQLAVGDIVYFVAQADQVQRALSLLGHDEVPGQRIVIAG
GGNIGYYVASELERRNAAARVKLIEFSRERAQTIAEVLSRTVVLNGDALERAILDEAGVREADTMISLTNDDRINILSCL
LAKQIGAKRILALLNEQGYATFARGLGIDAHVNPRQITVSKVLQHVRRGRIRGVHALLDGSGEMIEAEALETSPLVGKPL
KDLDLLEGLRIGAIVRNGQVLLPRGDFVVRAHDRVVLFALADRIKRVEQLFRVALEFF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=463, Percent_Identity=38.8768898488121, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49734; Mature: 49734

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVICGAGQVGFGIAERLAGEQNDVSIIDTSPRRIQMVTEQLDVRGVVGQGSHPDVLAR
CEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCEEECCCCCCCCHHHH
AGVEAADMLIAVTLHDEVNMVACQVGHALFNVPTKVARIRAQTYLAPEWRDLFSRDQLPI
CCCCHHCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCCCCE
DVIISPEIEVGEMVLRRLSLPGATDTVSFSDGAVQVVGVLCGEDCPVVDTPLSQLTQLFP
EEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHCC
DMPATIVAVSRKGKTLVPRSNDQLAVGDIVYFVAQADQVQRALSLLGHDEVPGQRIVIAG
CCCEEEEEEECCCCEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
GGNIGYYVASELERRNAAARVKLIEFSRERAQTIAEVLSRTVVLNGDALERAILDEAGVR
CCCEEEHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHCCCC
EADTMISLTNDDRINILSCLLAKQIGAKRILALLNEQGYATFARGLGIDAHVNPRQITVS
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEHH
KVLQHVRRGRIRGVHALLDGSGEMIEAEALETSPLVGKPLKDLDLLEGLRIGAIVRNGQV
HHHHHHHCCCCCEEEEEECCCCCEEEEHHCCCCCCCCCCCHHHHHHCCCEEEEEEECCEE
LLPRGDFVVRAHDRVVLFALADRIKRVEQLFRVALEFF
EEECCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVVICGAGQVGFGIAERLAGEQNDVSIIDTSPRRIQMVTEQLDVRGVVGQGSHPDVLAR
CEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCEEECCCCCCCCHHHH
AGVEAADMLIAVTLHDEVNMVACQVGHALFNVPTKVARIRAQTYLAPEWRDLFSRDQLPI
CCCCHHCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCCCCE
DVIISPEIEVGEMVLRRLSLPGATDTVSFSDGAVQVVGVLCGEDCPVVDTPLSQLTQLFP
EEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHCC
DMPATIVAVSRKGKTLVPRSNDQLAVGDIVYFVAQADQVQRALSLLGHDEVPGQRIVIAG
CCCEEEEEEECCCCEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
GGNIGYYVASELERRNAAARVKLIEFSRERAQTIAEVLSRTVVLNGDALERAILDEAGVR
CCCEEEHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHCCCC
EADTMISLTNDDRINILSCLLAKQIGAKRILALLNEQGYATFARGLGIDAHVNPRQITVS
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEHH
KVLQHVRRGRIRGVHALLDGSGEMIEAEALETSPLVGKPLKDLDLLEGLRIGAIVRNGQV
HHHHHHHCCCCCEEEEEECCCCCEEEEHHCCCCCCCCCCCHHHHHHCCCEEEEEEECCEE
LLPRGDFVVRAHDRVVLFALADRIKRVEQLFRVALEFF
EEECCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]