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The map label for this gene is bepF [H]

Identifier: 154248272

GI number: 154248272

Start: 4822820

End: 4823929

Strand: Direct

Name: bepF [H]

Synonym: Xaut_4352

Alternate gene names: 154248272

Gene position: 4822820-4823929 (Clockwise)

Preceding gene: 154248271

Following gene: 154248273

Centisome position: 90.84

GC content: 67.39

Gene sequence:

>1110_bases
ATGTCGCGCGCCCGTGCTGCCCGCATCGTTTCGCTGCTGTTGCTCGGTCTCCTATCTCCATGCGTTGCGCGCACCCAGGA
GGGCGGCATTCCGGTGGGCGTCGTTCCTGCCGCGCTCAAGCCCATCTCCGACGCCATGGAATTCGTCGGCCGCGTGGAGG
CGCCCGAACGCGTCGAGATCCGCGCCCGGGTGAAGGGCATGCTGGAAGCCGTCTTGTTCAAGGAGGGCGAGACGGTGAAG
GAGGGCGCACCACTCTACCGCATCGAGAAGCCGCTGTTCCAGGCGGATGTGGAGAATGCCGAAGGCAACGTGGAGCGGGC
CAAGGCCGCCCTGAGCCTGGCCAAGATCCAGCGCGAGCGCGCCGAGGAACTGGTCGCGAAGAATGCCGGCACGGTGGTGG
CCCGCGACCAGGCGGTGGCGAACGAGGAATCCTCCAAGGGCGCGCTGCTGTCCGCCGAAGCCAGCCTCCACACCACGCAG
ATCAATCTCGGCTACACCGACATCGTCTCCCCCATCACCGGCCGCATCGGCCGCTCGGCCGTCACCCGCGGCCACATCGT
GGGTCCGGAGAGTGGCGTGCTCGCCACCGTGGTGAGCCAGGATCCCATGTACGTCACCTTCCCCGTCAGCCAGCGCGACT
ATCTGGAGGCGCAGAAGGACGAGGGGAAGGTGGACCTCGCCAACGTGGAAGTGCGCATCAAGTTCTCCGATGGCGCGGTC
TATGGCGAGGTGGGGCGGGTGAATTTCGTGGACGTGTCGGTCAACCGCACCACCGACACCATGATCCTGCGCGCCGACGT
GCCCAACCCGAGCGGCAAGCTGGTGGACGGCCAGCTTGTCCGTGTGGAGCTGAAGGCGGGGACGCCGGAAGAACGGGTGG
TGATCCCGCAGGCGGCGCTGATCGCCGACCAGGCCGGCGTCTATGTGTTCGTGGTGGAGAACGGCAAGGCTGTGGTGCGC
CGGGTGAAAACCGGCGCCACCCAGGGGCCGAACATCATCATCACCGACGGCGTGAAGGCCGGCGAGCCGGTCATCGTGGA
GGGCTTCGAGAGCCTGAAGCCCGGCATCGCGGTGCGCGCGATCCCGACGGCCATCGGCCTGAAAGGCTGA

Upstream 100 bases:

>100_bases
CTTCCCACGCCACATACACCATCCGGTGTAATGGCGTGATCTGGGAAATGCCCGACCAAAAACGCCGCTGGGATGTTCCG
AGGATCTGGGGAGGACCGAC

Downstream 100 bases:

>100_bases
GCCATGCTCTCCTCCGTCTTCGTCGACCGCCCGCGGCTCGCCATCGTCATCGCCATCGTCACGACGATTGCCGGCCTGCT
CTCGCTGCTGGCCATCCCGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSRARAARIVSLLLLGLLSPCVARTQEGGIPVGVVPAALKPISDAMEFVGRVEAPERVEIRARVKGMLEAVLFKEGETVK
EGAPLYRIEKPLFQADVENAEGNVERAKAALSLAKIQRERAEELVAKNAGTVVARDQAVANEESSKGALLSAEASLHTTQ
INLGYTDIVSPITGRIGRSAVTRGHIVGPESGVLATVVSQDPMYVTFPVSQRDYLEAQKDEGKVDLANVEVRIKFSDGAV
YGEVGRVNFVDVSVNRTTDTMILRADVPNPSGKLVDGQLVRVELKAGTPEERVVIPQAALIADQAGVYVFVVENGKAVVR
RVKTGATQGPNIIITDGVKAGEPVIVEGFESLKPGIAVRAIPTAIGLKG

Sequences:

>Translated_369_residues
MSRARAARIVSLLLLGLLSPCVARTQEGGIPVGVVPAALKPISDAMEFVGRVEAPERVEIRARVKGMLEAVLFKEGETVK
EGAPLYRIEKPLFQADVENAEGNVERAKAALSLAKIQRERAEELVAKNAGTVVARDQAVANEESSKGALLSAEASLHTTQ
INLGYTDIVSPITGRIGRSAVTRGHIVGPESGVLATVVSQDPMYVTFPVSQRDYLEAQKDEGKVDLANVEVRIKFSDGAV
YGEVGRVNFVDVSVNRTTDTMILRADVPNPSGKLVDGQLVRVELKAGTPEERVVIPQAALIADQAGVYVFVVENGKAVVR
RVKTGATQGPNIIITDGVKAGEPVIVEGFESLKPGIAVRAIPTAIGLKG
>Mature_368_residues
SRARAARIVSLLLLGLLSPCVARTQEGGIPVGVVPAALKPISDAMEFVGRVEAPERVEIRARVKGMLEAVLFKEGETVKE
GAPLYRIEKPLFQADVENAEGNVERAKAALSLAKIQRERAEELVAKNAGTVVARDQAVANEESSKGALLSAEASLHTTQI
NLGYTDIVSPITGRIGRSAVTRGHIVGPESGVLATVVSQDPMYVTFPVSQRDYLEAQKDEGKVDLANVEVRIKFSDGAVY
GEVGRVNFVDVSVNRTTDTMILRADVPNPSGKLVDGQLVRVELKAGTPEERVVIPQAALIADQAGVYVFVVENGKAVVRR
VKTGATQGPNIIITDGVKAGEPVIVEGFESLKPGIAVRAIPTAIGLKG

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=364, Percent_Identity=33.2417582417582, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789929, Length=375, Percent_Identity=29.6, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789665, Length=373, Percent_Identity=30.5630026809651, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082036, Length=344, Percent_Identity=27.3255813953488, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87081796, Length=330, Percent_Identity=25.4545454545455, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39169; Mature: 39037

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRARAARIVSLLLLGLLSPCVARTQEGGIPVGVVPAALKPISDAMEFVGRVEAPERVEI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHH
RARVKGMLEAVLFKEGETVKEGAPLYRIEKPLFQADVENAEGNVERAKAALSLAKIQRER
HHHHHHHHHHHHHCCCCCHHCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AEELVAKNAGTVVARDQAVANEESSKGALLSAEASLHTTQINLGYTDIVSPITGRIGRSA
HHHHHHCCCCCEEECCHHHCCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHCCCHH
VTRGHIVGPESGVLATVVSQDPMYVTFPVSQRDYLEAQKDEGKVDLANVEVRIKFSDGAV
HCCCCEECCCCCEEEEEECCCCEEEEEECCCCHHHHCCCCCCCEEEEEEEEEEEECCCCE
YGEVGRVNFVDVSVNRTTDTMILRADVPNPSGKLVDGQLVRVELKAGTPEERVVIPQAAL
EECCCEEEEEEEEECCCCCEEEEEECCCCCCCCEECCEEEEEEEECCCCCCEEECCCHHE
IADQAGVYVFVVENGKAVVRRVKTGATQGPNIIITDGVKAGEPVIVEGFESLKPGIAVRA
EECCCCEEEEEEECCHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEECHHHCCCCEEEEE
IPTAIGLKG
ECHHCCCCC
>Mature Secondary Structure 
SRARAARIVSLLLLGLLSPCVARTQEGGIPVGVVPAALKPISDAMEFVGRVEAPERVEI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHH
RARVKGMLEAVLFKEGETVKEGAPLYRIEKPLFQADVENAEGNVERAKAALSLAKIQRER
HHHHHHHHHHHHHCCCCCHHCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AEELVAKNAGTVVARDQAVANEESSKGALLSAEASLHTTQINLGYTDIVSPITGRIGRSA
HHHHHHCCCCCEEECCHHHCCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHCCCHH
VTRGHIVGPESGVLATVVSQDPMYVTFPVSQRDYLEAQKDEGKVDLANVEVRIKFSDGAV
HCCCCEECCCCCEEEEEECCCCEEEEEECCCCHHHHCCCCCCCEEEEEEEEEEEECCCCE
YGEVGRVNFVDVSVNRTTDTMILRADVPNPSGKLVDGQLVRVELKAGTPEERVVIPQAAL
EECCCEEEEEEEEECCCCCEEEEEECCCCCCCCEECCEEEEEEEECCCCCCEEECCCHHE
IADQAGVYVFVVENGKAVVRRVKTGATQGPNIIITDGVKAGEPVIVEGFESLKPGIAVRA
EECCCCEEEEEEECCHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEECHHHCCCCEEEEE
IPTAIGLKG
ECHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]