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The map label for this gene is cidA [H]

Identifier: 154248256

GI number: 154248256

Start: 4808711

End: 4809199

Strand: Direct

Name: cidA [H]

Synonym: Xaut_4336

Alternate gene names: 154248256

Gene position: 4808711-4809199 (Clockwise)

Preceding gene: 154248254

Following gene: 154248257

Centisome position: 90.58

GC content: 66.67

Gene sequence:

>489_bases
ATGTCTGCCCCAATGTCTGCCCCCAAGCCTACTTCGACGACTTCACAGTCCTTTTCTCGCCTGCCCGTGTTGCGCAACAT
GCTGCGCAGCATGCGCATTACGCTGCATCGCAGCATGATCCTCCAGATCGCGGTTCTCGCCGGCTTCTGGGCCGTCGGGG
AGGCTACCGTGCGGCTCACCCATCTGCCTTTGCCTGGCGGCATTGTCGGCATGGTGGTGGTGCTGGCGCTGCTCGGCACC
GGCCACATCCGGCCCGCCGTGGTGCGGCGCGGGGCAGGGTGGCTGCTGGCTGAAATGCTGCTGTTCTTCGTTCCGGCGGT
GATGGCGATCCTCGACCATGGCGAGCTGATGGGCCTCGTCGGCCTCAAGATCGCCGCGGTGATCCTCGCCGGCACCGTCA
TGGTCATGGGTGGCACCGCGCTGGCGGTGGACCTGTGCTACCGCTGGCGCATGCGTTCGGCGACGCCGGAGGTGGGCCAT
GCTGCGTGA

Upstream 100 bases:

>100_bases
ATTATGGAATGAAATGAATTCAGTCAATTCATTTTCATCATGGTGCATCGCATACTATGTTGCCGGCAATGGCACTTCAG
GTGCTGAACGGTGTTTGCCC

Downstream 100 bases:

>100_bases
TCCGCTGTTCGCCGCCCTGTTCTGGTCGGCCGTCACCATCGGCTGCTATGCGGCGGCGCGGCTCATCGCCCGGCGCTGGC
GCTTCTGGTGGACCTCGCCG

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSAPMSAPKPTSTTSQSFSRLPVLRNMLRSMRITLHRSMILQIAVLAGFWAVGEATVRLTHLPLPGGIVGMVVVLALLGT
GHIRPAVVRRGAGWLLAEMLLFFVPAVMAILDHGELMGLVGLKIAAVILAGTVMVMGGTALAVDLCYRWRMRSATPEVGH
AA

Sequences:

>Translated_162_residues
MSAPMSAPKPTSTTSQSFSRLPVLRNMLRSMRITLHRSMILQIAVLAGFWAVGEATVRLTHLPLPGGIVGMVVVLALLGT
GHIRPAVVRRGAGWLLAEMLLFFVPAVMAILDHGELMGLVGLKIAAVILAGTVMVMGGTALAVDLCYRWRMRSATPEVGH
AA
>Mature_161_residues
SAPMSAPKPTSTTSQSFSRLPVLRNMLRSMRITLHRSMILQIAVLAGFWAVGEATVRLTHLPLPGGIVGMVVVLALLGTG
HIRPAVVRRGAGWLLAEMLLFFVPAVMAILDHGELMGLVGLKIAAVILAGTVMVMGGTALAVDLCYRWRMRSATPEVGHA
A

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 17235; Mature: 17104

Theoretical pI: Translated: 12.05; Mature: 12.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
7.4 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPMSAPKPTSTTSQSFSRLPVLRNMLRSMRITLHRSMILQIAVLAGFWAVGEATVRLT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEE
HLPLPGGIVGMVVVLALLGTGHIRPAVVRRGAGWLLAEMLLFFVPAVMAILDHGELMGLV
ECCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GLKIAAVILAGTVMVMGGTALAVDLCYRWRMRSATPEVGHAA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SAPMSAPKPTSTTSQSFSRLPVLRNMLRSMRITLHRSMILQIAVLAGFWAVGEATVRLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEE
HLPLPGGIVGMVVVLALLGTGHIRPAVVRRGAGWLLAEMLLFFVPAVMAILDHGELMGLV
ECCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GLKIAAVILAGTVMVMGGTALAVDLCYRWRMRSATPEVGHAA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA