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The map label for this gene is ywbI [H]

Identifier: 154248255

GI number: 154248255

Start: 4807709

End: 4808602

Strand: Reverse

Name: ywbI [H]

Synonym: Xaut_4335

Alternate gene names: 154248255

Gene position: 4808602-4807709 (Counterclockwise)

Preceding gene: 154248258

Following gene: 154248249

Centisome position: 90.58

GC content: 70.58

Gene sequence:

>894_bases
ATGGAACTGCGCTCCCTGAGGGTCTTTGTCGAGGTGGTGCGGCAGGGCGGATTTTCCGCCGCCGCCAAGGCGCTGTTTTC
CACCCAGCCCACCGTATCCAAGGCGGTGAAGCAGCTGGAGGACGAGCTGGGCGTTCCCCTGCTCGACCGCATCGGCCATC
GCAGCCAGCTGACCGCGGCGGGGGAGATCGTCTATCGCCGCGCCCTCACCCTGCTGGCGGAGCGGGAGGGGCTGGTGGCG
GAGTTGGACGACCTCAGGGGCCTGAGGCGCGGCAGCCTGCGCCTCGGCCTGCCGCCACTCGGCGCCAGCACGCTGTTCGC
GCCGCTGTTTGCCATTTTCCGCGCGCGCTATCCCGGCATCGAGATCCGCCTCACCGAGCACGGCTCGAAGCGGCTGGAGG
AAATGCTGCTGGATGGCGAGGTGGAACTGGCCGGCGCGCTGATGCCGGCGCGCGAGGGGTTCGACGGCCAGCCGGTGCGG
CACGAGCCGCTGATGGCCGTTCTGCCCAGGACCCACCCGCTGGCCGGGGCGGAAAGCATCGGCATCGCAGCGCTTGCGGC
CTCGCCCTTCATCCTGTTCGAGGGCGGCTTCTCGCTCAACCAGGTGCTGGAGGATGCCTGCGCCCGCAACGGCTTTGCGC
CGCAGGTCGCGGCGCGCAGCGGGCAGATCGATTTCATCGTGGAACTGGTGGGGGCGGGCCTCGGCGTCGCCTTCCTGCCC
CGCACCATCGCCGAGCAGCGGGCGACGCCCTCCATCGCCCTCGTCCGGCTCGATGAGCCGGGCACCGAATGGCAGATGGC
CATCGTCTGGCGGCAGGGCAGCTACCTGTCCCACGCCGCCCGCGCGTGGCTGGATCTCACCCGCGAAGTCTATGGCCCCG
AGGGTTCGGGCTGA

Upstream 100 bases:

>100_bases
ACCGTTCAGCACCTGAAGTGCCATTGCCGGCAACATAGTATGCGATGCACCATGATGAAAATGAATTGACTGAATTCATT
TCATTCCATAATCGCATAGT

Downstream 100 bases:

>100_bases
GGCGGCGTCGGCCCGGCGCCGGGTCCGAGGAAGGCAAAGGGCGCGCTTGGCGCGAAAGCGCTGCTCACCTCGCCCGAAAA
AATGTTGCCCTGGTTGGGTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MELRSLRVFVEVVRQGGFSAAAKALFSTQPTVSKAVKQLEDELGVPLLDRIGHRSQLTAAGEIVYRRALTLLAEREGLVA
ELDDLRGLRRGSLRLGLPPLGASTLFAPLFAIFRARYPGIEIRLTEHGSKRLEEMLLDGEVELAGALMPAREGFDGQPVR
HEPLMAVLPRTHPLAGAESIGIAALAASPFILFEGGFSLNQVLEDACARNGFAPQVAARSGQIDFIVELVGAGLGVAFLP
RTIAEQRATPSIALVRLDEPGTEWQMAIVWRQGSYLSHAARAWLDLTREVYGPEGSG

Sequences:

>Translated_297_residues
MELRSLRVFVEVVRQGGFSAAAKALFSTQPTVSKAVKQLEDELGVPLLDRIGHRSQLTAAGEIVYRRALTLLAEREGLVA
ELDDLRGLRRGSLRLGLPPLGASTLFAPLFAIFRARYPGIEIRLTEHGSKRLEEMLLDGEVELAGALMPAREGFDGQPVR
HEPLMAVLPRTHPLAGAESIGIAALAASPFILFEGGFSLNQVLEDACARNGFAPQVAARSGQIDFIVELVGAGLGVAFLP
RTIAEQRATPSIALVRLDEPGTEWQMAIVWRQGSYLSHAARAWLDLTREVYGPEGSG
>Mature_297_residues
MELRSLRVFVEVVRQGGFSAAAKALFSTQPTVSKAVKQLEDELGVPLLDRIGHRSQLTAAGEIVYRRALTLLAEREGLVA
ELDDLRGLRRGSLRLGLPPLGASTLFAPLFAIFRARYPGIEIRLTEHGSKRLEEMLLDGEVELAGALMPAREGFDGQPVR
HEPLMAVLPRTHPLAGAESIGIAALAASPFILFEGGFSLNQVLEDACARNGFAPQVAARSGQIDFIVELVGAGLGVAFLP
RTIAEQRATPSIALVRLDEPGTEWQMAIVWRQGSYLSHAARAWLDLTREVYGPEGSG

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=284, Percent_Identity=32.0422535211268, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787530, Length=280, Percent_Identity=27.5, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=29.4520547945205, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=32.3770491803279, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790399, Length=295, Percent_Identity=27.1186440677966, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI145693105, Length=307, Percent_Identity=26.3843648208469, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=28.2758620689655, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788748, Length=288, Percent_Identity=27.4305555555556, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789506, Length=296, Percent_Identity=21.9594594594595, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=27.2357723577236, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788296, Length=299, Percent_Identity=25.4180602006689, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790208, Length=256, Percent_Identity=28.125, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787806, Length=284, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786401, Length=119, Percent_Identity=38.655462184874, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=23.4817813765182, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=35.2459016393443, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789204, Length=240, Percent_Identity=22.9166666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693193, Length=141, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789440, Length=121, Percent_Identity=30.5785123966942, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32109; Mature: 32109

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRSLRVFVEVVRQGGFSAAAKALFSTQPTVSKAVKQLEDELGVPLLDRIGHRSQLTAA
CCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
GEIVYRRALTLLAEREGLVAELDDLRGLRRGSLRLGLPPLGASTLFAPLFAIFRARYPGI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCE
EIRLTEHGSKRLEEMLLDGEVELAGALMPAREGFDGQPVRHEPLMAVLPRTHPLAGAESI
EEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
GIAALAASPFILFEGGFSLNQVLEDACARNGFAPQVAARSGQIDFIVELVGAGLGVAFLP
CCHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHH
RTIAEQRATPSIALVRLDEPGTEWQMAIVWRQGSYLSHAARAWLDLTREVYGPEGSG
HHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELRSLRVFVEVVRQGGFSAAAKALFSTQPTVSKAVKQLEDELGVPLLDRIGHRSQLTAA
CCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
GEIVYRRALTLLAEREGLVAELDDLRGLRRGSLRLGLPPLGASTLFAPLFAIFRARYPGI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCE
EIRLTEHGSKRLEEMLLDGEVELAGALMPAREGFDGQPVRHEPLMAVLPRTHPLAGAESI
EEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
GIAALAASPFILFEGGFSLNQVLEDACARNGFAPQVAARSGQIDFIVELVGAGLGVAFLP
CCHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHH
RTIAEQRATPSIALVRLDEPGTEWQMAIVWRQGSYLSHAARAWLDLTREVYGPEGSG
HHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]