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The map label for this gene is yabD [H]

Identifier: 154248250

GI number: 154248250

Start: 4802719

End: 4803540

Strand: Direct

Name: yabD [H]

Synonym: Xaut_4330

Alternate gene names: 154248250

Gene position: 4802719-4803540 (Clockwise)

Preceding gene: 154248248

Following gene: 154248251

Centisome position: 90.46

GC content: 68.37

Gene sequence:

>822_bases
ATGCGCTTATGTGAGGCCGACCTTTCGAATGTGAATGCCATGCTTGTCGACAGCCATTGCCATCTCGATTTTCCCGACTT
CGCCGCCGAACTGCCCGACGTGGTGGCCCGCGCCGGCGCGGCCGGGGTGTCTCATCTCGTCACCATCTCCACCCGGGTGC
GGCGGTTTCCGCAGATCCTCGCCATCGCCGAGCGGTTCGATCAGGTGTCCTGCTCGGTGGGCACCCATCCCCACCAGGCG
GCGGAGGAGCTGGACGTGACCCTGGGCGAGATTGTCGCTCTCTCCCGCCATCCCAAGGTGGTGGCCATCGGCGAGGCCGG
GCTCGACTATCACTACGACACCAGCCCGCGCGACGCGCAGGAGCAGGGTTTCCGCACCCATATCGCGGCGGCGCGGGAGA
CCGGCCTGCCCCTGGTCATCCACGCCCGCGAGGCGGACGAGGATGTGGCCGCCATCCTGGAGGAGGAGAGCGCCAGGGGC
GCCTTCCCCTTCCTGCTCCACTGCTTCACGGCGGGGCCGGATCTGGCGCGCCGGGCGCTGGCGCTGGGCGGCTACATCTC
CTTCTCCGGCGTGGTGACCTTCAAGAAGAGTGAGGACCTGCGCGCCATCGCCGCCATCGTGCCGGCCGACCGCATCCTGG
TGGAGACCGATTCCCCCTTCCTCGCGCCCACGCCCTACCGCGGCAAGCGCAACGAGCCCTCCTTCGTGCGCGAGACCGCC
AAGGTGCTGGCCGAGGCGCGGGGCGAAGCGTTCGAGGACTTCGCGCAGGCCACCACGCGGAACTTCTTCACCCTTTTCTC
CAAGGCGAAAAGCCAGCCCTGA

Upstream 100 bases:

>100_bases
GCGGCGGCCTCCGTCAACGCCGTCACCCGGGGTATCAGGCCCGCGCGGCGCCAAAGCGCGGCCGCTCGCCTGACCCACCC
CACCTCGACGTGGCGGGGGG

Downstream 100 bases:

>100_bases
CATCACGAGGATGCGCCCGGTGAACCACGATCGTTACGACGACGCCTATATCCGCACCATCCTGTCGCAAGTGCGGACCA
TCGCCATCGTGGGCGCCAGC

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRLCEADLSNVNAMLVDSHCHLDFPDFAAELPDVVARAGAAGVSHLVTISTRVRRFPQILAIAERFDQVSCSVGTHPHQA
AEELDVTLGEIVALSRHPKVVAIGEAGLDYHYDTSPRDAQEQGFRTHIAAARETGLPLVIHAREADEDVAAILEEESARG
AFPFLLHCFTAGPDLARRALALGGYISFSGVVTFKKSEDLRAIAAIVPADRILVETDSPFLAPTPYRGKRNEPSFVRETA
KVLAEARGEAFEDFAQATTRNFFTLFSKAKSQP

Sequences:

>Translated_273_residues
MRLCEADLSNVNAMLVDSHCHLDFPDFAAELPDVVARAGAAGVSHLVTISTRVRRFPQILAIAERFDQVSCSVGTHPHQA
AEELDVTLGEIVALSRHPKVVAIGEAGLDYHYDTSPRDAQEQGFRTHIAAARETGLPLVIHAREADEDVAAILEEESARG
AFPFLLHCFTAGPDLARRALALGGYISFSGVVTFKKSEDLRAIAAIVPADRILVETDSPFLAPTPYRGKRNEPSFVRETA
KVLAEARGEAFEDFAQATTRNFFTLFSKAKSQP
>Mature_273_residues
MRLCEADLSNVNAMLVDSHCHLDFPDFAAELPDVVARAGAAGVSHLVTISTRVRRFPQILAIAERFDQVSCSVGTHPHQA
AEELDVTLGEIVALSRHPKVVAIGEAGLDYHYDTSPRDAQEQGFRTHIAAARETGLPLVIHAREADEDVAAILEEESARG
AFPFLLHCFTAGPDLARRALALGGYISFSGVVTFKKSEDLRAIAAIVPADRILVETDSPFLAPTPYRGKRNEPSFVRETA
KVLAEARGEAFEDFAQATTRNFFTLFSKAKSQP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=273, Percent_Identity=32.2344322344322, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI110349734, Length=273, Percent_Identity=32.2344322344322, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226061853, Length=281, Percent_Identity=32.7402135231317, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=30.7692307692308, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI225903424, Length=223, Percent_Identity=29.5964125560538, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI14042943, Length=266, Percent_Identity=24.812030075188, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI225903439, Length=224, Percent_Identity=25.4464285714286, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=42.7450980392157, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=31.5175097276265, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=33.206106870229, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=249, Percent_Identity=31.7269076305221, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=27.8625954198473, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=306, Percent_Identity=27.1241830065359, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=297, Percent_Identity=26.5993265993266, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=28.4210526315789, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221330018, Length=234, Percent_Identity=30.3418803418803, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24586117, Length=207, Percent_Identity=31.8840579710145, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29710; Mature: 29710

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLCEADLSNVNAMLVDSHCHLDFPDFAAELPDVVARAGAAGVSHLVTISTRVRRFPQIL
CCCCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AIAERFDQVSCSVGTHPHQAAEELDVTLGEIVALSRHPKVVAIGEAGLDYHYDTSPRDAQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHH
EQGFRTHIAAARETGLPLVIHAREADEDVAAILEEESARGAFPFLLHCFTAGPDLARRAL
HHCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHH
ALGGYISFSGVVTFKKSEDLRAIAAIVPADRILVETDSPFLAPTPYRGKRNEPSFVRETA
HHCCEEEECEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KVLAEARGEAFEDFAQATTRNFFTLFSKAKSQP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLCEADLSNVNAMLVDSHCHLDFPDFAAELPDVVARAGAAGVSHLVTISTRVRRFPQIL
CCCCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AIAERFDQVSCSVGTHPHQAAEELDVTLGEIVALSRHPKVVAIGEAGLDYHYDTSPRDAQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHH
EQGFRTHIAAARETGLPLVIHAREADEDVAAILEEESARGAFPFLLHCFTAGPDLARRAL
HHCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHH
ALGGYISFSGVVTFKKSEDLRAIAAIVPADRILVETDSPFLAPTPYRGKRNEPSFVRETA
HHCCEEEECEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KVLAEARGEAFEDFAQATTRNFFTLFSKAKSQP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]