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The map label for this gene is dacC [H]

Identifier: 154248244

GI number: 154248244

Start: 4796792

End: 4797991

Strand: Direct

Name: dacC [H]

Synonym: Xaut_4324

Alternate gene names: 154248244

Gene position: 4796792-4797991 (Clockwise)

Preceding gene: 154248243

Following gene: 154248245

Centisome position: 90.35

GC content: 67.83

Gene sequence:

>1200_bases
ATGCTGCCGAAGCTGCGCTTCGCCCTTCTTTTCGCAGCCCTCGCCTCGCTTGCCGGCGCTTCGAGCGCGCGGGCGGCTGA
CGGCTTTCAGACCCAGGCGCCCTCCGCCATCCTGGTGGATTACGAAACCGGGACCATCCTGTTCGAGAAGGATGCCGACC
GCCGCATCGCCCCCGGCACCCTCGCCAAGGTGATGACGGCTGACGTGGTGTTCTCTCAGCTCAAGGCCGGCAAGATCGCC
CTCGACACCCCGTTCACCGTGAGCGTCAACGCCTGGCGCCGCGGCGGAGGCCCCTCGGGCGGGGCGGCCATGTTCGCCGA
GGTGAACAAGCCGGCCCCGGTGGGCGAGCTGCTCGCCGGCATGCTGGTGGTTTCGGGTAATGATGCGGCCATCGCCCTGG
CGGAGGGCGTCGGCGGCACCGAGACCGAGTTCTCCCAGCAGATGACGGAGCGGGCCAAGGCCATCGGCATGGCCAATTCC
GAGTTCCGCAACGCCACCGGCTTTGCAGATCCGGGCCAGTTCTCCACCGCCCGCGACCTGTCGGTGCTGGCCCAGCATGT
CATCCGCACCTATCCCGACTATTACCCGGTGTTCGCGCGGACCAGCATCGAGTGGAGCCGCATCAAGCAGCGCAACCGCA
ACGTGCTGCTGGATGCGGGCATCGGCGCCGACGGGCTGCAGATCGGCTGGGTGAAGGATGTGGGCTACCATGCCCTCGGC
TCGGCGGTGCAGAACGGCCAGCGGCTCATCGTGGTAGTGCTGGCGGCCAAGACCGAGAAGGAGCGGCTCGAGGAGGCCAA
GAAGCTGCTGGAGTGGGGTTTCCAGTCGTTCCGGCAGCGGGTGATCTTTACCGCCGACCAGGAGGTGGGCCGCGCTCAGG
TGTTCGGCGGCGCCTCCGGCACCGTCGGGCTCGTGGGGTCACGGCCGGTGACCGTGCTCACCCCGCGCTCGGGCAATGAG
CGTATCACCGCCCGCGTGGTCTATAATGGGCCGCTGCTGGCGCCGGTGACCAAGGGCACCCAGGTGGGACGGCTGGAAGT
CACGCGCGGCCAGACCAAGGTGCTGGAAATGCCTCTTTATACGCAGGAGGACGTGCCGGTGGGTTCGCTGACGGATCGCG
CCCTCGACGGCGGGCTGACGCTGATGGGCGACAGCGTGCGCGATCTGGCCAAGCGCGCTCTGGCGAAGATTCACAAATGA

Upstream 100 bases:

>100_bases
ATGATGATCGCCGCGCACCGCCGGCTGCGCAGGCGAGTCTCGGCCGACGAGTCTTGCCTGCGGCGGCCTTGGCCGGTTCG
GGATAGCCAGGTGGATCAAC

Downstream 100 bases:

>100_bases
CCCAGGGGCGATTCATCACGCTGGAAGGCGGGGAGGGGACCGGCAAGTCCACCCAGGCCCGCCGCCTCGCGGCGCATCTG
CGCACCCTTGGCCACACGGT

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLPKLRFALLFAALASLAGASSARAADGFQTQAPSAILVDYETGTILFEKDADRRIAPGTLAKVMTADVVFSQLKAGKIA
LDTPFTVSVNAWRRGGGPSGGAAMFAEVNKPAPVGELLAGMLVVSGNDAAIALAEGVGGTETEFSQQMTERAKAIGMANS
EFRNATGFADPGQFSTARDLSVLAQHVIRTYPDYYPVFARTSIEWSRIKQRNRNVLLDAGIGADGLQIGWVKDVGYHALG
SAVQNGQRLIVVVLAAKTEKERLEEAKKLLEWGFQSFRQRVIFTADQEVGRAQVFGGASGTVGLVGSRPVTVLTPRSGNE
RITARVVYNGPLLAPVTKGTQVGRLEVTRGQTKVLEMPLYTQEDVPVGSLTDRALDGGLTLMGDSVRDLAKRALAKIHK

Sequences:

>Translated_399_residues
MLPKLRFALLFAALASLAGASSARAADGFQTQAPSAILVDYETGTILFEKDADRRIAPGTLAKVMTADVVFSQLKAGKIA
LDTPFTVSVNAWRRGGGPSGGAAMFAEVNKPAPVGELLAGMLVVSGNDAAIALAEGVGGTETEFSQQMTERAKAIGMANS
EFRNATGFADPGQFSTARDLSVLAQHVIRTYPDYYPVFARTSIEWSRIKQRNRNVLLDAGIGADGLQIGWVKDVGYHALG
SAVQNGQRLIVVVLAAKTEKERLEEAKKLLEWGFQSFRQRVIFTADQEVGRAQVFGGASGTVGLVGSRPVTVLTPRSGNE
RITARVVYNGPLLAPVTKGTQVGRLEVTRGQTKVLEMPLYTQEDVPVGSLTDRALDGGLTLMGDSVRDLAKRALAKIHK
>Mature_399_residues
MLPKLRFALLFAALASLAGASSARAADGFQTQAPSAILVDYETGTILFEKDADRRIAPGTLAKVMTADVVFSQLKAGKIA
LDTPFTVSVNAWRRGGGPSGGAAMFAEVNKPAPVGELLAGMLVVSGNDAAIALAEGVGGTETEFSQQMTERAKAIGMANS
EFRNATGFADPGQFSTARDLSVLAQHVIRTYPDYYPVFARTSIEWSRIKQRNRNVLLDAGIGADGLQIGWVKDVGYHALG
SAVQNGQRLIVVVLAAKTEKERLEEAKKLLEWGFQSFRQRVIFTADQEVGRAQVFGGASGTVGLVGSRPVTVLTPRSGNE
RITARVVYNGPLLAPVTKGTQVGRLEVTRGQTKVLEMPLYTQEDVPVGSLTDRALDGGLTLMGDSVRDLAKRALAKIHK

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=374, Percent_Identity=34.7593582887701, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI87082022, Length=379, Percent_Identity=33.245382585752, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1786851, Length=351, Percent_Identity=32.4786324786325, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42530; Mature: 42530

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKLRFALLFAALASLAGASSARAADGFQTQAPSAILVDYETGTILFEKDADRRIAPGT
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHH
LAKVMTADVVFSQLKAGKIALDTPFTVSVNAWRRGGGPSGGAAMFAEVNKPAPVGELLAG
HHHHHHHHHHHHHHCCCEEEECCCEEEEEECEECCCCCCCCCEEEEECCCCCCHHHHHHC
MLVVSGNDAAIALAEGVGGTETEFSQQMTERAKAIGMANSEFRNATGFADPGQFSTARDL
EEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHH
SVLAQHVIRTYPDYYPVFARTSIEWSRIKQRNRNVLLDAGIGADGLQIGWVKDVGYHALG
HHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCEEEECCCCCCCEEEEEEHHCCHHHHH
SAVQNGQRLIVVVLAAKTEKERLEEAKKLLEWGFQSFRQRVIFTADQEVGRAQVFGGASG
HHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
TVGLVGSRPVTVLTPRSGNERITARVVYNGPLLAPVTKGTQVGRLEVTRGQTKVLEMPLY
CEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCEEEEECCCEEEEECCCC
TQEDVPVGSLTDRALDGGLTLMGDSVRDLAKRALAKIHK
CCCCCCCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPKLRFALLFAALASLAGASSARAADGFQTQAPSAILVDYETGTILFEKDADRRIAPGT
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHH
LAKVMTADVVFSQLKAGKIALDTPFTVSVNAWRRGGGPSGGAAMFAEVNKPAPVGELLAG
HHHHHHHHHHHHHHCCCEEEECCCEEEEEECEECCCCCCCCCEEEEECCCCCCHHHHHHC
MLVVSGNDAAIALAEGVGGTETEFSQQMTERAKAIGMANSEFRNATGFADPGQFSTARDL
EEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHH
SVLAQHVIRTYPDYYPVFARTSIEWSRIKQRNRNVLLDAGIGADGLQIGWVKDVGYHALG
HHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCEEEECCCCCCCEEEEEEHHCCHHHHH
SAVQNGQRLIVVVLAAKTEKERLEEAKKLLEWGFQSFRQRVIFTADQEVGRAQVFGGASG
HHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
TVGLVGSRPVTVLTPRSGNERITARVVYNGPLLAPVTKGTQVGRLEVTRGQTKVLEMPLY
CEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCEEEEECCCEEEEECCCC
TQEDVPVGSLTDRALDGGLTLMGDSVRDLAKRALAKIHK
CCCCCCCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]