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The map label for this gene is crtE [H]

Identifier: 154248054

GI number: 154248054

Start: 4573915

End: 4574847

Strand: Reverse

Name: crtE [H]

Synonym: Xaut_4133

Alternate gene names: 154248054

Gene position: 4574847-4573915 (Counterclockwise)

Preceding gene: 154248056

Following gene: 154248053

Centisome position: 86.17

GC content: 70.85

Gene sequence:

>933_bases
GTGCAGGAGCTGGAAGAGCCGGCAACCGCCGCCTTCCCGCCGCGCTCGCGCGACCTATCCTTCCTGCGGGCGGTGATCGA
TCGCCGGCTCGGCCTGCTGGTGCCGCCCGCCGCGTCCCACCCGGCCGTGCTGCATGCCGCCATGCGGCACATCCTGCTCT
CGCCCGGCAAACGGCTGCGACCCCTTCTCACCCTTGCCGCCGCGATCCAGCTCAACGCCTCCGAGCATGCGGTGCTGGAT
TTTGGCTGCGCGCTGGAGATGATCCACGCCTCCTCGCTGATCGTGGACGACCTCCCGTGCATGGACGACGCCGCCATGCG
CCGCGCCCAGCCCACCACCCATGTGCAGTACGGCGAGGATGTCGCGGTGCTGGCCTCCATTGGCCTTTTGTCGCGCGCCT
TCGGGGTGGCGGCGGCAGCGCCGGGGGTGAGCGAGCGTGCGCGCCTAGAAGCGGTCGCCATCCTCTCCATGGCGGTGGGC
TCGCTGGGCCTGTGCGGCGGCCAGTATGATGACCTGCGCCCGAGCCCCGGCCGCAGCCTGTCCGCTACCGAGGACGTGAA
CCGCCGCAAGACCGGCGTGCTGTTCTCGGCCGCTGTGGAGATCGCCGGCCATGTGGCGGCCGCCGACGAGACCCAGATGG
GCCACCTGAAGGCCCTGGCCGGCCATGTCGGCCGCGCATATCAGATCCTCGACGACATTCTGGATGCCTCCGCCTCTTCC
GCCAGCCTCGGCAAGGACGTGGGCAAGGATGCCCACAAGGCCACCGTCATCGCCTCCCTCGGCGCGCCGCGCGCGCGCAA
GCTCCTGTCCGAGCACCTGGCGGGCGCCCTTGCCACCTCTCAGGAGCTGGGACCCAACACGGAAGGCCAGGAGCCCCTGC
GCGATTTCATGACCGCCGCCTTCGGCGAACTGATGGGGCCGCTGGCGCCGTGA

Upstream 100 bases:

>100_bases
CGACGTGCTGCGGCCAGGCTCGTCCCACGGCGCGTCGCAAGGTGGTTCCACCCTGGTGCTGGCCGTGGCGGAGCCGGAGA
CCCGGGCACCGGAAGGTCGC

Downstream 100 bases:

>100_bases
GCGCCGCGTCCCGATACGACCTCCAGGTGGAAGACCCGGCCCCGGCACTCACACCGGCCCCGCCCCTCGCCATCTCGGGC
CTTCACGTGGGCTATGGCGC

Product: polyprenyl synthetase

Products: NA

Alternate protein names: GGPP synthase; Farnesyltranstransferase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MQELEEPATAAFPPRSRDLSFLRAVIDRRLGLLVPPAASHPAVLHAAMRHILLSPGKRLRPLLTLAAAIQLNASEHAVLD
FGCALEMIHASSLIVDDLPCMDDAAMRRAQPTTHVQYGEDVAVLASIGLLSRAFGVAAAAPGVSERARLEAVAILSMAVG
SLGLCGGQYDDLRPSPGRSLSATEDVNRRKTGVLFSAAVEIAGHVAAADETQMGHLKALAGHVGRAYQILDDILDASASS
ASLGKDVGKDAHKATVIASLGAPRARKLLSEHLAGALATSQELGPNTEGQEPLRDFMTAAFGELMGPLAP

Sequences:

>Translated_310_residues
MQELEEPATAAFPPRSRDLSFLRAVIDRRLGLLVPPAASHPAVLHAAMRHILLSPGKRLRPLLTLAAAIQLNASEHAVLD
FGCALEMIHASSLIVDDLPCMDDAAMRRAQPTTHVQYGEDVAVLASIGLLSRAFGVAAAAPGVSERARLEAVAILSMAVG
SLGLCGGQYDDLRPSPGRSLSATEDVNRRKTGVLFSAAVEIAGHVAAADETQMGHLKALAGHVGRAYQILDDILDASASS
ASLGKDVGKDAHKATVIASLGAPRARKLLSEHLAGALATSQELGPNTEGQEPLRDFMTAAFGELMGPLAP
>Mature_310_residues
MQELEEPATAAFPPRSRDLSFLRAVIDRRLGLLVPPAASHPAVLHAAMRHILLSPGKRLRPLLTLAAAIQLNASEHAVLD
FGCALEMIHASSLIVDDLPCMDDAAMRRAQPTTHVQYGEDVAVLASIGLLSRAFGVAAAAPGVSERARLEAVAILSMAVG
SLGLCGGQYDDLRPSPGRSLSATEDVNRRKTGVLFSAAVEIAGHVAAADETQMGHLKALAGHVGRAYQILDDILDASASS
ASLGKDVGKDAHKATVIASLGAPRARKLLSEHLAGALATSQELGPNTEGQEPLRDFMTAAFGELMGPLAP

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=273, Percent_Identity=38.0952380952381, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789578, Length=208, Percent_Identity=27.4038461538462, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.29 [H]

Molecular weight: Translated: 32356; Mature: 32356

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELEEPATAAFPPRSRDLSFLRAVIDRRLGLLVPPAASHPAVLHAAMRHILLSPGKRLR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCHHHH
PLLTLAAAIQLNASEHAVLDFGCALEMIHASSLIVDDLPCMDDAAMRRAQPTTHVQYGED
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCH
VAVLASIGLLSRAFGVAAAAPGVSERARLEAVAILSMAVGSLGLCGGQYDDLRPSPGRSL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SATEDVNRRKTGVLFSAAVEIAGHVAAADETQMGHLKALAGHVGRAYQILDDILDASASS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ASLGKDVGKDAHKATVIASLGAPRARKLLSEHLAGALATSQELGPNTEGQEPLRDFMTAA
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FGELMGPLAP
HHHHHCCCCC
>Mature Secondary Structure
MQELEEPATAAFPPRSRDLSFLRAVIDRRLGLLVPPAASHPAVLHAAMRHILLSPGKRLR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCHHHH
PLLTLAAAIQLNASEHAVLDFGCALEMIHASSLIVDDLPCMDDAAMRRAQPTTHVQYGED
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCH
VAVLASIGLLSRAFGVAAAAPGVSERARLEAVAILSMAVGSLGLCGGQYDDLRPSPGRSL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SATEDVNRRKTGVLFSAAVEIAGHVAAADETQMGHLKALAGHVGRAYQILDDILDASASS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ASLGKDVGKDAHKATVIASLGAPRARKLLSEHLAGALATSQELGPNTEGQEPLRDFMTAA
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FGELMGPLAP
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2263648; 1495965 [H]