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The map label for this gene is dctB [H]

Identifier: 154247970

GI number: 154247970

Start: 4479387

End: 4481279

Strand: Reverse

Name: dctB [H]

Synonym: Xaut_4049

Alternate gene names: 154247970

Gene position: 4481279-4479387 (Counterclockwise)

Preceding gene: 154247971

Following gene: 154247969

Centisome position: 84.41

GC content: 70.79

Gene sequence:

>1893_bases
ATGCGCCCCGATCTCGCCACCGCAGCGCGCGCCATGCTCCTCGCCGTTCTCGGCGCGGCAGCACTGTTCGCCGTGGTGAA
GGCGGGGGAGATGGCGGAGGCCCGCGTCGGCGAGCGCCTCGCCAGCGAGGCCCGCCACCGCAGCGAGATCTATGCCCAGA
GCCTGGAGGGCGCCATCGAGCGGTTCGGCTATCTGCCCGCCGCCGCCGCCCTCGACCTCAATGTGCGCAGCGCCCTCGTC
CAGCCCGACGACCCGAGGCTGATCGCCACCGTCAACACCTATCTGGAAACCCTCAACCGCGCTGCCGGGGCCAGCGTGCT
CTATCTCATCGACCCCTCGGGCATGACCATCGCCGCGTCCAACTGGGACACGCGGGAGACCTATGTGGGCGTGGACTTCA
GCTATCGCCCCTATTTCACCGAGGCCATGGCGGGCCAGGCCGGCCGGTTCTACGCCATCGGCACGCTGACCGGCGTGCCC
GGCTATTTCATCAGCGCCCCGGTGGCGATCGACGGCAGGATCCGGGGCGTGGTGGTCACCAAGGTCAATCTCGACCCCTT
GGAGGCGGTGTGGCAGGAGGCCGCCGACCGGGTGCTGGTGACCGACCCGAATGGCATCGTCTTCCTCGCCTCCGATACGC
GCTTCAAGTTCCACGCTACCCGCCCCATCGATGCCGCCACCGCGCAGGAATTGAAAAAGACTCGCCAATACGGGCGCAAG
ACCTATCCGCTGCTCAATCTCGGCACGGTGGAGACGGTGGGCGGCGTGCCTCTGATCGCGGCCTCGGACGTGGCCCCTCA
CGGCCGTGTCATCGCCGACGACAAGCCCCTTGTCCCCTATGACTGGCACCTGCTGCTGTTTGCAGACGCCGCCGCGCTGG
AGCTGGCCGGGCGCACCGCCCGCGTGGGCATGACGCTGGGCTTCGGCGTGCTCGGCCTCATCGGCCTCTATTGGTGGCAG
CACCTCAAGCGCGCCCGCGAGAGCCTCGCCGCCCGCGCGGCACTGGAGGCGGCGCAGCGCGAGCTGGAAGCCAAGGTGGA
AGCCCGCACCGCCGACCTCACCGCCGCCAACGGCCAGCTCGCGGGCGAGATCGAGGAACGCCGCCGCGCCGAGGCGGAGC
TGCGCGCCGCGCAGGACGAGCTGGTGCAGGCCGCCAAGATGGCGACCCTCGGCCAGATGGCGGCCGGCATCACCCATGAG
CTGAACCAGCCCCTCACCGCCTTGCGCGGCCTCGCCGACAATGCCGGCAAGCTTTTGGAGCAGGGGCGCGAGGAGGAGGC
GCAGGCCAATCTCGGCCGCATCACCGCCATGGTGGACCGGCTCGGCAAGATCACCGGGCAGTTGCGCGCCTTCGCCCGCA
AGAGCAGCAGCGAGACGCTGCCGGTGGACGTGGCGGCGGCGGTGGCCGAGAGCCTCGCCATCCTCGCCCCGCGCATCCGC
GTCGCCGGCATCGGCGTCCAGACCGACCTCGACGCGGCCGCTGCCACCGTGCGGTTCGAACCCATCCGCCTCAGCCAGGT
TCTGGTGAACCTCGTGGGCAACGCGCTGGACGCGGTGAAGGGTCGGCCTAGCGCCTGGGTCGGCCTTTCCACCCGGCGCG
AGGGCTCCCGCATCGTCCTCAGCGTGGAGGACAACGGCCCCGGCCTGCCGGAGGCCACCCTCGCGCGCATCTTCGATCCC
TTCTTCACCACCAAGCCGGCGGGCGAGGGGCTGGGGCTGGGCCTGCCCATCTCGCTCGCCATCGCCCGCGAATTCGGCGC
CACCCTCACCGCCCGCGCGCGAACAGGCGGCGGCCTCGCCTTCGATCTCGTCATGGAGGCTGCGGAGAGCGCGGACGCCG
CCCCGCCCCAGCCGGAAAGATTGCGCCACGAAAGGACGCACCATGTGTGCTGA

Upstream 100 bases:

>100_bases
GCCGGGATGAGCATCCGCCGGCGCCCACCCTCGGGCGCCGGCTAAAGACAAGGACCGCGCCACGGCGGCCAAGCGGCCAG
GGAGCCGACGGACCAGGACC

Downstream 100 bases:

>100_bases
GCGCGCCCTCAAGTCCACTCCCGCCCCGCACCCGGCCGCCCGGCCCCGCGTGGTGCTGGTGGACGACGAGGAGATGATCC
GCATCACCATCGAGCAGACG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MRPDLATAARAMLLAVLGAAALFAVVKAGEMAEARVGERLASEARHRSEIYAQSLEGAIERFGYLPAAAALDLNVRSALV
QPDDPRLIATVNTYLETLNRAAGASVLYLIDPSGMTIAASNWDTRETYVGVDFSYRPYFTEAMAGQAGRFYAIGTLTGVP
GYFISAPVAIDGRIRGVVVTKVNLDPLEAVWQEAADRVLVTDPNGIVFLASDTRFKFHATRPIDAATAQELKKTRQYGRK
TYPLLNLGTVETVGGVPLIAASDVAPHGRVIADDKPLVPYDWHLLLFADAAALELAGRTARVGMTLGFGVLGLIGLYWWQ
HLKRARESLAARAALEAAQRELEAKVEARTADLTAANGQLAGEIEERRRAEAELRAAQDELVQAAKMATLGQMAAGITHE
LNQPLTALRGLADNAGKLLEQGREEEAQANLGRITAMVDRLGKITGQLRAFARKSSSETLPVDVAAAVAESLAILAPRIR
VAGIGVQTDLDAAAATVRFEPIRLSQVLVNLVGNALDAVKGRPSAWVGLSTRREGSRIVLSVEDNGPGLPEATLARIFDP
FFTTKPAGEGLGLGLPISLAIAREFGATLTARARTGGGLAFDLVMEAAESADAAPPQPERLRHERTHHVC

Sequences:

>Translated_630_residues
MRPDLATAARAMLLAVLGAAALFAVVKAGEMAEARVGERLASEARHRSEIYAQSLEGAIERFGYLPAAAALDLNVRSALV
QPDDPRLIATVNTYLETLNRAAGASVLYLIDPSGMTIAASNWDTRETYVGVDFSYRPYFTEAMAGQAGRFYAIGTLTGVP
GYFISAPVAIDGRIRGVVVTKVNLDPLEAVWQEAADRVLVTDPNGIVFLASDTRFKFHATRPIDAATAQELKKTRQYGRK
TYPLLNLGTVETVGGVPLIAASDVAPHGRVIADDKPLVPYDWHLLLFADAAALELAGRTARVGMTLGFGVLGLIGLYWWQ
HLKRARESLAARAALEAAQRELEAKVEARTADLTAANGQLAGEIEERRRAEAELRAAQDELVQAAKMATLGQMAAGITHE
LNQPLTALRGLADNAGKLLEQGREEEAQANLGRITAMVDRLGKITGQLRAFARKSSSETLPVDVAAAVAESLAILAPRIR
VAGIGVQTDLDAAAATVRFEPIRLSQVLVNLVGNALDAVKGRPSAWVGLSTRREGSRIVLSVEDNGPGLPEATLARIFDP
FFTTKPAGEGLGLGLPISLAIAREFGATLTARARTGGGLAFDLVMEAAESADAAPPQPERLRHERTHHVC
>Mature_630_residues
MRPDLATAARAMLLAVLGAAALFAVVKAGEMAEARVGERLASEARHRSEIYAQSLEGAIERFGYLPAAAALDLNVRSALV
QPDDPRLIATVNTYLETLNRAAGASVLYLIDPSGMTIAASNWDTRETYVGVDFSYRPYFTEAMAGQAGRFYAIGTLTGVP
GYFISAPVAIDGRIRGVVVTKVNLDPLEAVWQEAADRVLVTDPNGIVFLASDTRFKFHATRPIDAATAQELKKTRQYGRK
TYPLLNLGTVETVGGVPLIAASDVAPHGRVIADDKPLVPYDWHLLLFADAAALELAGRTARVGMTLGFGVLGLIGLYWWQ
HLKRARESLAARAALEAAQRELEAKVEARTADLTAANGQLAGEIEERRRAEAELRAAQDELVQAAKMATLGQMAAGITHE
LNQPLTALRGLADNAGKLLEQGREEEAQANLGRITAMVDRLGKITGQLRAFARKSSSETLPVDVAAAVAESLAILAPRIR
VAGIGVQTDLDAAAATVRFEPIRLSQVLVNLVGNALDAVKGRPSAWVGLSTRREGSRIVLSVEDNGPGLPEATLARIFDP
FFTTKPAGEGLGLGLPISLAIAREFGATLTARARTGGGLAFDLVMEAAESADAAPPQPERLRHERTHHVC

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=288, Percent_Identity=29.5138888888889, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=29.646017699115, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081816, Length=278, Percent_Identity=31.294964028777, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=267, Percent_Identity=28.4644194756554, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=31.2217194570136, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=29.7297297297297, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=26.6094420600858, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67203; Mature: 67203

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDLATAARAMLLAVLGAAALFAVVKAGEMAEARVGERLASEARHRSEIYAQSLEGAIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGYLPAAAALDLNVRSALVQPDDPRLIATVNTYLETLNRAAGASVLYLIDPSGMTIAAS
HHCCCCCHHHCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCEEEEC
NWDTRETYVGVDFSYRPYFTEAMAGQAGRFYAIGTLTGVPGYFISAPVAIDGRIRGVVVT
CCCCCCEEEEECCCCCCCHHHHHCCCCCCEEEEEEECCCCCHHEECCEEECCEEEEEEEE
KVNLDPLEAVWQEAADRVLVTDPNGIVFLASDTRFKFHATRPIDAATAQELKKTRQYGRK
EECCCHHHHHHHHHCCEEEEECCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHCCC
TYPLLNLGTVETVGGVPLIAASDVAPHGRVIADDKPLVPYDWHLLLFADAAALELAGRTA
CCCEEECCCCHHCCCCCEEEECCCCCCCEEEECCCCCCCCCCEEEEEECHHHHHHCCCCE
RVGMTLGFGVLGLIGLYWWQHLKRARESLAARAALEAAQRELEAKVEARTADLTAANGQL
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCH
AGEIEERRRAEAELRAAQDELVQAAKMATLGQMAAGITHELNQPLTALRGLADNAGKLLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
QGREEEAQANLGRITAMVDRLGKITGQLRAFARKSSSETLPVDVAAAVAESLAILAPRIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEE
VAGIGVQTDLDAAAATVRFEPIRLSQVLVNLVGNALDAVKGRPSAWVGLSTRREGSRIVL
EEECCCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
SVEDNGPGLPEATLARIFDPFFTTKPAGEGLGLGLPISLAIAREFGATLTARARTGGGLA
EEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCHH
FDLVMEAAESADAAPPQPERLRHERTHHVC
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRPDLATAARAMLLAVLGAAALFAVVKAGEMAEARVGERLASEARHRSEIYAQSLEGAIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGYLPAAAALDLNVRSALVQPDDPRLIATVNTYLETLNRAAGASVLYLIDPSGMTIAAS
HHCCCCCHHHCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCEEEEC
NWDTRETYVGVDFSYRPYFTEAMAGQAGRFYAIGTLTGVPGYFISAPVAIDGRIRGVVVT
CCCCCCEEEEECCCCCCCHHHHHCCCCCCEEEEEEECCCCCHHEECCEEECCEEEEEEEE
KVNLDPLEAVWQEAADRVLVTDPNGIVFLASDTRFKFHATRPIDAATAQELKKTRQYGRK
EECCCHHHHHHHHHCCEEEEECCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHCCC
TYPLLNLGTVETVGGVPLIAASDVAPHGRVIADDKPLVPYDWHLLLFADAAALELAGRTA
CCCEEECCCCHHCCCCCEEEECCCCCCCEEEECCCCCCCCCCEEEEEECHHHHHHCCCCE
RVGMTLGFGVLGLIGLYWWQHLKRARESLAARAALEAAQRELEAKVEARTADLTAANGQL
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCH
AGEIEERRRAEAELRAAQDELVQAAKMATLGQMAAGITHELNQPLTALRGLADNAGKLLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
QGREEEAQANLGRITAMVDRLGKITGQLRAFARKSSSETLPVDVAAAVAESLAILAPRIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEE
VAGIGVQTDLDAAAATVRFEPIRLSQVLVNLVGNALDAVKGRPSAWVGLSTRREGSRIVL
EEECCCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
SVEDNGPGLPEATLARIFDPFFTTKPAGEGLGLGLPISLAIAREFGATLTARARTGGGLA
EEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCHH
FDLVMEAAESADAAPPQPERLRHERTHHVC
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]