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The map label for this gene is pcoA [H]

Identifier: 154247515

GI number: 154247515

Start: 4010827

End: 4012095

Strand: Reverse

Name: pcoA [H]

Synonym: Xaut_3588

Alternate gene names: 154247515

Gene position: 4012095-4010827 (Counterclockwise)

Preceding gene: 154247522

Following gene: 154247513

Centisome position: 75.57

GC content: 72.5

Gene sequence:

>1269_bases
GTGACGACGCCGATTCCCTCCCGACGCACCGTCCTCAAGGGTGCTGCAGCCCTCTCCCTGTCCGGCGCGGCGGGCGCGCT
CGTGCCGGCGCTCGCGCAATCGCCGGCCGCTGCGCAGGCGGCGGCGCCCCCCGCCGCGCAGGCCACCCCCCCGGTGACGC
TCACCGCCGCCGAAGGCAGCCTACCGGAGCTGGCCGGACCGGGGCCGCTCGCCCTATTCAACGGCGCCCTCCCCGGCCCG
GTGCTGCGGGTGAAGAAGGGCGGCATGCTAAATGTCACCCTCGCCAACAGCCTGAAAGAAAACGTCGCCCTGACCTGGCA
GGGCGTGCGGCTGCCAGCGGGTTCGCCCGCGCTGGCGTCGGTCGCGCCCGGCAAGAGCGCCAACCTCAGTCTCGTGGCCA
CGGATGCCGGCACGTTCTGGTATCATGCGACCTCGCCTAGCCTCGCCCGCCGCGCCCTTGCCGGCCCGCTGGTGGTGGAG
GAGGCCGGCGCCTCGGCCTATGCGGCGGACCACCTGTTGTTCATCCAGTCGTTTCCGCCGGAGAGCGGGGTGCCCATCTT
TCCGGTCAACGGCGCTATCTCGCCCACCTTCCAGGGTCCGGCCGGCGGGCGCGCCCGGCTGCGGCTGGTGAACGCGACCC
CGCTGTTCCTGCGCCTGAAGATTCGCGGGCCGGCGAGCTATGCCATCGCGGTGGACGGCCAGCCCGTGTCCGAGCCCTTC
GAACTGAAGGACGGCCGCATCCAGATCGCCCCCGGCGGCCGGGTGGACGTGGCGGCGACGCTGGACGACGCCGACGCCAC
CATCATCGAGATCGAGACCACGCAGGACCCCATCCGGCTGGCGGTGGTGACCCCGGTGGGCGCCGCCGTCACGCCACCGA
CCGGGGCGCCGGCGCCGCTGCCGCCCAACGACCTGCCGGCCGAGATCCCCCTCAAGGACGCCCTGCGCATCGAGCTGCCC
ATCGGCGACAAGCCGGGCGCGGGGGCAGCCTCCCTCGGCACCGTGAAGGCCGGCAAGAGCGTGGTGCTGACACTGGTGAA
CAGCCTCGACGCGCCGGTGTCGGTCTATATCGCCGGTCATCCCGTGCGCCTGCTGGACAATGTCTATGACGGCTGGCGGC
CGTGGTGGCACGACACCGTGCCGGTGCCGTCAAAGGCCACAGTGCGGGTAGCGTTCCGCGCCGCCCAGCCGGGCACCTGG
TCCATCATCGGCCAGCGCGGCGGCGACGGCGAGGTGGTGGTCTCCAAGACCTATGAAGTGACGGCCTGA

Upstream 100 bases:

>100_bases
CCCAGGAACCTGCTTAGGCCGTGAAAATCAGCGGTGGAAAGCCGCTTGCCCTTTTTCCAGCCACGTATGAAGGTCCACGC
ACCCTGCCAGGAGACGCCGC

Downstream 100 bases:

>100_bases
GGCCCGGAGAATTTTCCGCGAGCGACCAGGACGGCCCGGGCTGTCCTGGTCACCGCACCCCGAGCGTTTCGTACAGCCGG
CGGTAGACCTCGCGCAGCGC

Product: multicopper oxidase type 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTTPIPSRRTVLKGAAALSLSGAAGALVPALAQSPAAAQAAAPPAAQATPPVTLTAAEGSLPELAGPGPLALFNGALPGP
VLRVKKGGMLNVTLANSLKENVALTWQGVRLPAGSPALASVAPGKSANLSLVATDAGTFWYHATSPSLARRALAGPLVVE
EAGASAYAADHLLFIQSFPPESGVPIFPVNGAISPTFQGPAGGRARLRLVNATPLFLRLKIRGPASYAIAVDGQPVSEPF
ELKDGRIQIAPGGRVDVAATLDDADATIIEIETTQDPIRLAVVTPVGAAVTPPTGAPAPLPPNDLPAEIPLKDALRIELP
IGDKPGAGAASLGTVKAGKSVVLTLVNSLDAPVSVYIAGHPVRLLDNVYDGWRPWWHDTVPVPSKATVRVAFRAAQPGTW
SIIGQRGGDGEVVVSKTYEVTA

Sequences:

>Translated_422_residues
MTTPIPSRRTVLKGAAALSLSGAAGALVPALAQSPAAAQAAAPPAAQATPPVTLTAAEGSLPELAGPGPLALFNGALPGP
VLRVKKGGMLNVTLANSLKENVALTWQGVRLPAGSPALASVAPGKSANLSLVATDAGTFWYHATSPSLARRALAGPLVVE
EAGASAYAADHLLFIQSFPPESGVPIFPVNGAISPTFQGPAGGRARLRLVNATPLFLRLKIRGPASYAIAVDGQPVSEPF
ELKDGRIQIAPGGRVDVAATLDDADATIIEIETTQDPIRLAVVTPVGAAVTPPTGAPAPLPPNDLPAEIPLKDALRIELP
IGDKPGAGAASLGTVKAGKSVVLTLVNSLDAPVSVYIAGHPVRLLDNVYDGWRPWWHDTVPVPSKATVRVAFRAAQPGTW
SIIGQRGGDGEVVVSKTYEVTA
>Mature_421_residues
TTPIPSRRTVLKGAAALSLSGAAGALVPALAQSPAAAQAAAPPAAQATPPVTLTAAEGSLPELAGPGPLALFNGALPGPV
LRVKKGGMLNVTLANSLKENVALTWQGVRLPAGSPALASVAPGKSANLSLVATDAGTFWYHATSPSLARRALAGPLVVEE
AGASAYAADHLLFIQSFPPESGVPIFPVNGAISPTFQGPAGGRARLRLVNATPLFLRLKIRGPASYAIAVDGQPVSEPFE
LKDGRIQIAPGGRVDVAATLDDADATIIEIETTQDPIRLAVVTPVGAAVTPPTGAPAPLPPNDLPAEIPLKDALRIELPI
GDKPGAGAASLGTVKAGKSVVLTLVNSLDAPVSVYIAGHPVRLLDNVYDGWRPWWHDTVPVPSKATVRVAFRAAQPGTWS
IIGQRGGDGEVVVSKTYEVTA

Specific function: Required for the copper-inducible expression of copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789394, Length=372, Percent_Identity=25.2688172043011, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 42966; Mature: 42834

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPIPSRRTVLKGAAALSLSGAAGALVPALAQSPAAAQAAAPPAAQATPPVTLTAAEGS
CCCCCCCCHHHHCCCEEEEECCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCEEEEECCCC
LPELAGPGPLALFNGALPGPVLRVKKGGMLNVTLANSLKENVALTWQGVRLPAGSPALAS
CCCCCCCCCEEEECCCCCCCEEEEECCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCEE
VAPGKSANLSLVATDAGTFWYHATSPSLARRALAGPLVVEEAGASAYAADHLLFIQSFPP
ECCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCEEEECCCCCCEECEEEEEEECCCC
ESGVPIFPVNGAISPTFQGPAGGRARLRLVNATPLFLRLKIRGPASYAIAVDGQPVSEPF
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCEEEEEECCCCCCCCC
ELKDGRIQIAPGGRVDVAATLDDADATIIEIETTQDPIRLAVVTPVGAAVTPPTGAPAPL
CCCCCEEEECCCCCEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCEECCCCCCCCCC
PPNDLPAEIPLKDALRIELPIGDKPGAGAASLGTVKAGKSVVLTLVNSLDAPVSVYIAGH
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCCCCEEEEEHHCCCCCEEEEECCC
PVRLLDNVYDGWRPWWHDTVPVPSKATVRVAFRAAQPGTWSIIGQRGGDGEVVVSKTYEV
CHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEE
TA
CC
>Mature Secondary Structure 
TTPIPSRRTVLKGAAALSLSGAAGALVPALAQSPAAAQAAAPPAAQATPPVTLTAAEGS
CCCCCCCHHHHCCCEEEEECCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCEEEEECCCC
LPELAGPGPLALFNGALPGPVLRVKKGGMLNVTLANSLKENVALTWQGVRLPAGSPALAS
CCCCCCCCCEEEECCCCCCCEEEEECCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCEE
VAPGKSANLSLVATDAGTFWYHATSPSLARRALAGPLVVEEAGASAYAADHLLFIQSFPP
ECCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCEEEECCCCCCEECEEEEEEECCCC
ESGVPIFPVNGAISPTFQGPAGGRARLRLVNATPLFLRLKIRGPASYAIAVDGQPVSEPF
CCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCEEEEEECCCCCCCCC
ELKDGRIQIAPGGRVDVAATLDDADATIIEIETTQDPIRLAVVTPVGAAVTPPTGAPAPL
CCCCCEEEECCCCCEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCEECCCCCCCCCC
PPNDLPAEIPLKDALRIELPIGDKPGAGAASLGTVKAGKSVVLTLVNSLDAPVSVYIAGH
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCCCCEEEEEHHCCCCCEEEEECCC
PVRLLDNVYDGWRPWWHDTVPVPSKATVRVAFRAAQPGTWSIIGQRGGDGEVVVSKTYEV
CHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEE
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]