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The map label for this gene is pabB [H]

Identifier: 154247509

GI number: 154247509

Start: 4004419

End: 4005843

Strand: Reverse

Name: pabB [H]

Synonym: Xaut_3582

Alternate gene names: 154247509

Gene position: 4005843-4004419 (Counterclockwise)

Preceding gene: 154247512

Following gene: 154247508

Centisome position: 75.45

GC content: 71.23

Gene sequence:

>1425_bases
TTGTGCCCAGCGTTTCGAATCGGTCGCCCTGCCGTGCTTATCGTTGAAATTCCGTACCGCGACCCGTTCGCCGTCCTCCA
CGCCTTCGCCGATGCGCCCTATTGCGCCTTCCTCGACAGCGCCGCGGAGGGGGACGCGCGGGCACGCTGGTCCTATCTGG
GGGCCGATCCGTTCCAGGTCATCACCAGCGCGGCCGATGGCGTGCGCGTGGACGGACGGCTCGTGCCCGGCACTCCGTTC
GAGGTTCTGTCTGTGGCGCTGGCCGCCAATGCGGCGCCGGCCGAACCCTCCCCGGTGCCGTTTCGCGGCGGCGCCATGGG
GTATCTCGGCTATGAGCTGGGCCGCCATCTGGAGCGCCTGCCCGCCCCCCGCCCGGCAGCCCCGGCCATTCCCGAGCTGG
TTCTCGGCCTCTACGACACGGTGCTCGCCTTCGACCGTCTGGAGCGCCGCGCCTACATCGTTTCCACCGGCCGGCCGGAG
CATGGCGCCGCCGCCAAGGCGCGCGCGCAGGTCCGGGCCGAGGCGATCCGCCGCCGGCTGGAGACGGCCCCCGCCATCGC
GCCGGCGCCGGATTTTTCCCGCACCGGCCGCTTCGTGCCGGAGCAGCCGCGCGCCCAGGTGGAAGCCGCCATCGCGCGGG
TGATCGAATACATCCGCGCCGGCGACATCTTCCAGGCCAACCTCACCCAGCAGATGCGCGCGGCGCGGCCCCAGGGGCTC
AGCGATCTAGCCCTCTACACCCGCCTGCGCGCGCTCTCCCCCTCCCCCTTCGCCGCCTTCCTGCGCGCCGGACCGGAGCT
TGCCGTGCTCAGCGCCTCACCGGAGCGCTTCCTCTCCCTCGATCCCGACGGGCGGGTGGAGACGCGGCCCATCAAGGGCA
CCCGCCGCCGCAGCCCGGACCCGCAGGAGGACGCGCGGCTTGCCGCCGCCCTCCTCGCCTCGCCCAAGGACCGGGCGGAA
AACCTGATGATCGTGGACCTGCTGCGCAACGACCTCTCGCGGGTCTGCAAGGTGGGCAGCGTGAAGGTGCCGGCCCTGTG
CGCGCTGGAGACCTTCGCCAGTGTGCATCACCTGGTCTCGGTGGTGGAAGGCCGGCTGAAAGACGGCCTCGGCCCGGTGG
ACCTGCTCACCGCCTGCTTTCCCGGCGGGTCCATCACGGGAGCGCCGAAGATCCGCGCCATGGAGATCATCCACGAGCTG
GAACCGGTGCCGCGCGGGGTCTATTGCGGCTCGGTGTGCTGGATCGGCTTCGACGGGGCGATGGATTCCTCCATCGTCAT
CCGCACCATAACCCGGGCCGGGGAGACGCTGCTGGCCCAGGCGGGCGGCGGCATCGTGGCGGATTCCGATCCGGCGGACG
AATATGAGGAGAGCCTGGTGAAGCTCTCGCCCATGCTGCGGGCCTTGTCGGGGGAGACATCGTGA

Upstream 100 bases:

>100_bases
AGGCGATACACGACGGCCATGCAGCGATGGGGTAGCTTTGCGTCAGGTGCCTCCCTCCGGACCATCGCGCGCATTGCCCC
CGGGGGCCGGGGACGCCATC

Downstream 100 bases:

>100_bases
AGCTCTGGCTCGGCACCGGCCTCGTCGCGCAGGACGATGCGCGCCTCTCCCCGTTCGACCGGGGCTTCACCCTCGGCGAC
GGCCTGTTCGAGACCCTGCG

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MCPAFRIGRPAVLIVEIPYRDPFAVLHAFADAPYCAFLDSAAEGDARARWSYLGADPFQVITSAADGVRVDGRLVPGTPF
EVLSVALAANAAPAEPSPVPFRGGAMGYLGYELGRHLERLPAPRPAAPAIPELVLGLYDTVLAFDRLERRAYIVSTGRPE
HGAAAKARAQVRAEAIRRRLETAPAIAPAPDFSRTGRFVPEQPRAQVEAAIARVIEYIRAGDIFQANLTQQMRAARPQGL
SDLALYTRLRALSPSPFAAFLRAGPELAVLSASPERFLSLDPDGRVETRPIKGTRRRSPDPQEDARLAAALLASPKDRAE
NLMIVDLLRNDLSRVCKVGSVKVPALCALETFASVHHLVSVVEGRLKDGLGPVDLLTACFPGGSITGAPKIRAMEIIHEL
EPVPRGVYCGSVCWIGFDGAMDSSIVIRTITRAGETLLAQAGGGIVADSDPADEYEESLVKLSPMLRALSGETS

Sequences:

>Translated_474_residues
MCPAFRIGRPAVLIVEIPYRDPFAVLHAFADAPYCAFLDSAAEGDARARWSYLGADPFQVITSAADGVRVDGRLVPGTPF
EVLSVALAANAAPAEPSPVPFRGGAMGYLGYELGRHLERLPAPRPAAPAIPELVLGLYDTVLAFDRLERRAYIVSTGRPE
HGAAAKARAQVRAEAIRRRLETAPAIAPAPDFSRTGRFVPEQPRAQVEAAIARVIEYIRAGDIFQANLTQQMRAARPQGL
SDLALYTRLRALSPSPFAAFLRAGPELAVLSASPERFLSLDPDGRVETRPIKGTRRRSPDPQEDARLAAALLASPKDRAE
NLMIVDLLRNDLSRVCKVGSVKVPALCALETFASVHHLVSVVEGRLKDGLGPVDLLTACFPGGSITGAPKIRAMEIIHEL
EPVPRGVYCGSVCWIGFDGAMDSSIVIRTITRAGETLLAQAGGGIVADSDPADEYEESLVKLSPMLRALSGETS
>Mature_474_residues
MCPAFRIGRPAVLIVEIPYRDPFAVLHAFADAPYCAFLDSAAEGDARARWSYLGADPFQVITSAADGVRVDGRLVPGTPF
EVLSVALAANAAPAEPSPVPFRGGAMGYLGYELGRHLERLPAPRPAAPAIPELVLGLYDTVLAFDRLERRAYIVSTGRPE
HGAAAKARAQVRAEAIRRRLETAPAIAPAPDFSRTGRFVPEQPRAQVEAAIARVIEYIRAGDIFQANLTQQMRAARPQGL
SDLALYTRLRALSPSPFAAFLRAGPELAVLSASPERFLSLDPDGRVETRPIKGTRRRSPDPQEDARLAAALLASPKDRAE
NLMIVDLLRNDLSRVCKVGSVKVPALCALETFASVHHLVSVVEGRLKDGLGPVDLLTACFPGGSITGAPKIRAMEIIHEL
EPVPRGVYCGSVCWIGFDGAMDSSIVIRTITRAGETLLAQAGGGIVADSDPADEYEESLVKLSPMLRALSGETS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=442, Percent_Identity=39.5927601809955, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1787518, Length=409, Percent_Identity=32.0293398533007, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1786809, Length=271, Percent_Identity=28.0442804428044, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082077, Length=208, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=436, Percent_Identity=34.4036697247706, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6324361, Length=400, Percent_Identity=28.25, Blast_Score=142, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50763; Mature: 50763

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCPAFRIGRPAVLIVEIPYRDPFAVLHAFADAPYCAFLDSAAEGDARARWSYLGADPFQV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCCCHHHH
ITSAADGVRVDGRLVPGTPFEVLSVALAANAAPAEPSPVPFRGGAMGYLGYELGRHLERL
HHHCCCCEEECCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
PAPRPAAPAIPELVLGLYDTVLAFDRLERRAYIVSTGRPEHGAAAKARAQVRAEAIRRRL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
ETAPAIAPAPDFSRTGRFVPEQPRAQVEAAIARVIEYIRAGDIFQANLTQQMRAARPQGL
HHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCH
SDLALYTRLRALSPSPFAAFLRAGPELAVLSASPERFLSLDPDGRVETRPIKGTRRRSPD
HHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCHHEEECCCCCCEECCCCCCCCCCCCC
PQEDARLAAALLASPKDRAENLMIVDLLRNDLSRVCKVGSVKVPALCALETFASVHHLVS
CHHHHHHHHHHHCCCHHHHCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VVEGRLKDGLGPVDLLTACFPGGSITGAPKIRAMEIIHELEPVPRGVYCGSVCWIGFDGA
HHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCEEEEEECCC
MDSSIVIRTITRAGETLLAQAGGGIVADSDPADEYEESLVKLSPMLRALSGETS
CCCHHHHHHHHHCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MCPAFRIGRPAVLIVEIPYRDPFAVLHAFADAPYCAFLDSAAEGDARARWSYLGADPFQV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHCCCCHHHH
ITSAADGVRVDGRLVPGTPFEVLSVALAANAAPAEPSPVPFRGGAMGYLGYELGRHLERL
HHHCCCCEEECCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
PAPRPAAPAIPELVLGLYDTVLAFDRLERRAYIVSTGRPEHGAAAKARAQVRAEAIRRRL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
ETAPAIAPAPDFSRTGRFVPEQPRAQVEAAIARVIEYIRAGDIFQANLTQQMRAARPQGL
HHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCH
SDLALYTRLRALSPSPFAAFLRAGPELAVLSASPERFLSLDPDGRVETRPIKGTRRRSPD
HHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCHHEEECCCCCCEECCCCCCCCCCCCC
PQEDARLAAALLASPKDRAENLMIVDLLRNDLSRVCKVGSVKVPALCALETFASVHHLVS
CHHHHHHHHHHHCCCHHHHCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VVEGRLKDGLGPVDLLTACFPGGSITGAPKIRAMEIIHELEPVPRGVYCGSVCWIGFDGA
HHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCEEEEEECCC
MDSSIVIRTITRAGETLLAQAGGGIVADSDPADEYEESLVKLSPMLRALSGETS
CCCHHHHHHHHHCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]