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The map label for this gene is rkpK [H]

Identifier: 154247478

GI number: 154247478

Start: 3962773

End: 3964089

Strand: Reverse

Name: rkpK [H]

Synonym: Xaut_3551

Alternate gene names: 154247478

Gene position: 3964089-3962773 (Counterclockwise)

Preceding gene: 154247491

Following gene: 154247477

Centisome position: 74.67

GC content: 66.14

Gene sequence:

>1317_bases
ATGCGTGTGACCATGATCGGAGCGGGCTATGTGGGCTTGGTCTCCGGCGCGTGCTTTGCGGATTTCGGCCATACGGTTAC
GTGCGTCGACACGCACGAGGGCAAGATTGCGGCGCTGAAGCGCGGTGAAATCCCGATCTTCGAGCCCGGCCTCGACGATC
TCGTGGCCTCGAACGTGAAAGCCGAGAGGCTGTTCTTCACCACCAGCCTTGCCGAAGGCGTCGCCGATGCGGAAGCCGTG
TTCATCGCGGTGGGCACGCCGTCGCGGCGCGGCGACGGCCATGCCGACCTCTCCTACGTGCATCAGGCCGCCCGCGACAT
CGCCAGCGCGATGACGGGCTATACGGTGATCGTGACCAAATCCACCGTGCCCGTCGGCACCGGCGACGAGGTGGAGCGCA
TCATCCGCGAGACCCGGCCGGACGCTGAATTCTCCGTCGTCTCCAACCCCGAGTTCCTGCGCGAAGGCGCCGCCATCATC
GATTTCAAGCGGCCCGACCGCATCGTGGTGGGCACCGACGAGGAGCGCGCCAAGGAGGTCATGACCAACCTCTACCGCCC
GCTGTTCCTCAACCAGTCGCCGCTGCTGTTCACCTCGCGCCGCACCGCCGAACTGATCAAGTATGCGGCCAACGCCTTCC
TCGCCACCAAGATCACCTTCATCAACGAGATCTCGGACCTGTGCGAGAAGGTGGGCGGCAACGTCCAGGACGTGGCCCGC
GGCATCGGCCTCGACAACCGCATCGGCTCCAAGTTCCTGCACGCGGGTCCCGGCTACGGCGGATCCTGCTTCCCGAAGGA
CACTCTGGCCCTCATCAAGACCGCCCAGGACTATGATGCGCCCATCCGCATCGTGGAGACGGTCGTGTCGGTGAACGACC
AGCGCAAGCGCGCCATGGCCCGCAAGGTCATCACCGCGCTCGGCGGATCGGTGCGCGGCAAGACCGTCGGCGTGCTGGGC
CTCACCTTCAAGCCGAACACCGACGACATGCGCGACGCGCCGTCCATCGCCATCATCACCGCCCTTCAGGATGCCGGCGC
CACCATCCGGGCGCACGATCCCGAAGGCGTTGAGCAGGCCAAGATGGTGCTGAGCAACGTCGACTATGTGGATAGCCCCT
ATCAGGCGGCGGACGGGGCCGACGCCCTGGTCATCGTCACCGAATGGGACGCCTTCCGCGCCCTCGACCTCAAGCGCATC
CAGTCGATGATGGCCCAGCCGGTGGTGGTGGACCTGCGCAACATCTACCGCCCCGAGGAGATGGCGAGCCTCGGCTTCAG
GTACAGCAGCGTCGGGCGCGGCCTCGCCGACCTCTGA

Upstream 100 bases:

>100_bases
AAAATCCATTGAGATTTTGGCCACGGGGGGCTAATCCCTGCTGCGATGCAACATGCGACCGAAGCCTTAGGGCGAAAGTT
GCACAAAACAGGGCTGGGCC

Downstream 100 bases:

>100_bases
GACTGAGGTCGCGGATGCCGGAAGACACTCCGACCGGATTGTGCCGCAATCCGGTCGGTTGACCGTGCTTCCACCCAGGC
CTGACGGCGGACTTGAGGCT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRVTMIGAGYVGLVSGACFADFGHTVTCVDTHEGKIAALKRGEIPIFEPGLDDLVASNVKAERLFFTTSLAEGVADAEAV
FIAVGTPSRRGDGHADLSYVHQAARDIASAMTGYTVIVTKSTVPVGTGDEVERIIRETRPDAEFSVVSNPEFLREGAAII
DFKRPDRIVVGTDEERAKEVMTNLYRPLFLNQSPLLFTSRRTAELIKYAANAFLATKITFINEISDLCEKVGGNVQDVAR
GIGLDNRIGSKFLHAGPGYGGSCFPKDTLALIKTAQDYDAPIRIVETVVSVNDQRKRAMARKVITALGGSVRGKTVGVLG
LTFKPNTDDMRDAPSIAIITALQDAGATIRAHDPEGVEQAKMVLSNVDYVDSPYQAADGADALVIVTEWDAFRALDLKRI
QSMMAQPVVVDLRNIYRPEEMASLGFRYSSVGRGLADL

Sequences:

>Translated_438_residues
MRVTMIGAGYVGLVSGACFADFGHTVTCVDTHEGKIAALKRGEIPIFEPGLDDLVASNVKAERLFFTTSLAEGVADAEAV
FIAVGTPSRRGDGHADLSYVHQAARDIASAMTGYTVIVTKSTVPVGTGDEVERIIRETRPDAEFSVVSNPEFLREGAAII
DFKRPDRIVVGTDEERAKEVMTNLYRPLFLNQSPLLFTSRRTAELIKYAANAFLATKITFINEISDLCEKVGGNVQDVAR
GIGLDNRIGSKFLHAGPGYGGSCFPKDTLALIKTAQDYDAPIRIVETVVSVNDQRKRAMARKVITALGGSVRGKTVGVLG
LTFKPNTDDMRDAPSIAIITALQDAGATIRAHDPEGVEQAKMVLSNVDYVDSPYQAADGADALVIVTEWDAFRALDLKRI
QSMMAQPVVVDLRNIYRPEEMASLGFRYSSVGRGLADL
>Mature_438_residues
MRVTMIGAGYVGLVSGACFADFGHTVTCVDTHEGKIAALKRGEIPIFEPGLDDLVASNVKAERLFFTTSLAEGVADAEAV
FIAVGTPSRRGDGHADLSYVHQAARDIASAMTGYTVIVTKSTVPVGTGDEVERIIRETRPDAEFSVVSNPEFLREGAAII
DFKRPDRIVVGTDEERAKEVMTNLYRPLFLNQSPLLFTSRRTAELIKYAANAFLATKITFINEISDLCEKVGGNVQDVAR
GIGLDNRIGSKFLHAGPGYGGSCFPKDTLALIKTAQDYDAPIRIVETVVSVNDQRKRAMARKVITALGGSVRGKTVGVLG
LTFKPNTDDMRDAPSIAIITALQDAGATIRAHDPEGVEQAKMVLSNVDYVDSPYQAADGADALVIVTEWDAFRALDLKRI
QSMMAQPVVVDLRNIYRPEEMASLGFRYSSVGRGLADL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=464, Percent_Identity=38.3620689655172, Blast_Score=311, Evalue=9e-85,
Organism=Homo sapiens, GI296040438, Length=365, Percent_Identity=38.9041095890411, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI296040443, Length=314, Percent_Identity=39.4904458598726, Blast_Score=222, Evalue=4e-58,
Organism=Escherichia coli, GI1788340, Length=356, Percent_Identity=30.6179775280899, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI48994968, Length=437, Percent_Identity=29.5194508009153, Blast_Score=165, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17560350, Length=463, Percent_Identity=36.9330453563715, Blast_Score=287, Evalue=9e-78,
Organism=Drosophila melanogaster, GI17136908, Length=463, Percent_Identity=38.0129589632829, Blast_Score=296, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47306; Mature: 47306

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTMIGAGYVGLVSGACFADFGHTVTCVDTHEGKIAALKRGEIPIFEPGLDDLVASNVK
CEEEEEECCHHHHHCCHHHHCCCCEEEEEECCCCCEEEEECCCCCEECCCHHHHHHCCCC
AERLFFTTSLAEGVADAEAVFIAVGTPSRRGDGHADLSYVHQAARDIASAMTGYTVIVTK
HHHEEEEHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEE
STVPVGTGDEVERIIRETRPDAEFSVVSNPEFLREGAAIIDFKRPDRIVVGTDEERAKEV
CCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHCCCEEEEECCCCEEEEECCHHHHHHH
MTNLYRPLFLNQSPLLFTSRRTAELIKYAANAFLATKITFINEISDLCEKVGGNVQDVAR
HHHHCCHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIGLDNRIGSKFLHAGPGYGGSCFPKDTLALIKTAQDYDAPIRIVETVVSVNDQRKRAMA
HCCCCCHHCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
RKVITALGGSVRGKTVGVLGLTFKPNTDDMRDAPSIAIITALQDAGATIRAHDPEGVEQA
HHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHH
KMVLSNVDYVDSPYQAADGADALVIVTEWDAFRALDLKRIQSMMAQPVVVDLRNIYRPEE
HHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
MASLGFRYSSVGRGLADL
HHHHCCCHHHHCCCCCCC
>Mature Secondary Structure
MRVTMIGAGYVGLVSGACFADFGHTVTCVDTHEGKIAALKRGEIPIFEPGLDDLVASNVK
CEEEEEECCHHHHHCCHHHHCCCCEEEEEECCCCCEEEEECCCCCEECCCHHHHHHCCCC
AERLFFTTSLAEGVADAEAVFIAVGTPSRRGDGHADLSYVHQAARDIASAMTGYTVIVTK
HHHEEEEHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEE
STVPVGTGDEVERIIRETRPDAEFSVVSNPEFLREGAAIIDFKRPDRIVVGTDEERAKEV
CCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHCCCEEEEECCCCEEEEECCHHHHHHH
MTNLYRPLFLNQSPLLFTSRRTAELIKYAANAFLATKITFINEISDLCEKVGGNVQDVAR
HHHHCCHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIGLDNRIGSKFLHAGPGYGGSCFPKDTLALIKTAQDYDAPIRIVETVVSVNDQRKRAMA
HCCCCCHHCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
RKVITALGGSVRGKTVGVLGLTFKPNTDDMRDAPSIAIITALQDAGATIRAHDPEGVEQA
HHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHH
KMVLSNVDYVDSPYQAADGADALVIVTEWDAFRALDLKRIQSMMAQPVVVDLRNIYRPEE
HHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
MASLGFRYSSVGRGLADL
HHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]