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The map label for this gene is rfbC [C]

Identifier: 154247475

GI number: 154247475

Start: 3959107

End: 3959673

Strand: Reverse

Name: rfbC [C]

Synonym: Xaut_3548

Alternate gene names: 154247475

Gene position: 3959673-3959107 (Counterclockwise)

Preceding gene: 154247477

Following gene: 154247474

Centisome position: 74.59

GC content: 65.43

Gene sequence:

>567_bases
ATGACGGCCTTTCAAGCGCTCGACCTGCCAGAGGTCATCCTCGTGACGCCGCGCCGCTTCGGCGACGCGCGCGGCTATTT
CTGCGAAACCTACGTCAAGCCGCTCTATGCGGCGAACGGGATCGTCGCCGATTTCGTACAGGACAACGAATCGCTGTCGG
CGCTGCCGGGCACGGTGCGCGGCCTCCACATGCAAGCGCCCCCCTTCGCGCAGGCCAAGCTGGTGCGGGTGCTGAGCGGC
GCCATCTTCGACGTGGCGGTGGATGTGCGGAAGGGCTCGCCCACCTACGGCCGCTGGGCCGGCGCCCGCCTCACCGCCGA
GGGCGGCGAACAGCTGTTTGTGCCGCAGGGTTTCGCCCACGGCTTCTGCACCCTCGCCCCCGACACGCGCGTCGCCTATA
AGGTGGACGCGTTTTATGATCGGGCGAGCGAATGCGGGATTATCTGGAACGATCCCGACCTCGCCATCGACTGGCGCTTC
ACCGGCGAGACCATTCTCTCCGACAAGGACCGGATATTGCCTCGCCTCAAGGATTTCGACAGTCCCTTCGTGCATTCGAA
CGGATAG

Upstream 100 bases:

>100_bases
CGACCTGCGGCGGGCGCCACACCGGGCTGGTCCGGGCCGGCGCCGGTCTCCGCCGCACCGCACCGTTGCCTTCGCCGTGC
GGCAGCCCTAGAAGCGCGCC

Downstream 100 bases:

>100_bases
CCGCGCGCCTGAAGCAGGGGCAGAGGCAATTGTGAAGGGAACGGCATGCGGGTTCTGGTGACCGGAGGAGCGGGCTTCAT
CGGCTCGGCGGTGGTGCGGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MTAFQALDLPEVILVTPRRFGDARGYFCETYVKPLYAANGIVADFVQDNESLSALPGTVRGLHMQAPPFAQAKLVRVLSG
AIFDVAVDVRKGSPTYGRWAGARLTAEGGEQLFVPQGFAHGFCTLAPDTRVAYKVDAFYDRASECGIIWNDPDLAIDWRF
TGETILSDKDRILPRLKDFDSPFVHSNG

Sequences:

>Translated_188_residues
MTAFQALDLPEVILVTPRRFGDARGYFCETYVKPLYAANGIVADFVQDNESLSALPGTVRGLHMQAPPFAQAKLVRVLSG
AIFDVAVDVRKGSPTYGRWAGARLTAEGGEQLFVPQGFAHGFCTLAPDTRVAYKVDAFYDRASECGIIWNDPDLAIDWRF
TGETILSDKDRILPRLKDFDSPFVHSNG
>Mature_187_residues
TAFQALDLPEVILVTPRRFGDARGYFCETYVKPLYAANGIVADFVQDNESLSALPGTVRGLHMQAPPFAQAKLVRVLSGA
IFDVAVDVRKGSPTYGRWAGARLTAEGGEQLFVPQGFAHGFCTLAPDTRVAYKVDAFYDRASECGIIWNDPDLAIDWRFT
GETILSDKDRILPRLKDFDSPFVHSNG

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=173, Percent_Identity=43.9306358381503, Blast_Score=149, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17550412, Length=166, Percent_Identity=42.7710843373494, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20704; Mature: 20572

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFQALDLPEVILVTPRRFGDARGYFCETYVKPLYAANGIVADFVQDNESLSALPGTVR
CCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
GLHMQAPPFAQAKLVRVLSGAIFDVAVDVRKGSPTYGRWAGARLTAEGGEQLFVPQGFAH
EEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCC
GFCTLAPDTRVAYKVDAFYDRASECGIIWNDPDLAIDWRFTGETILSDKDRILPRLKDFD
CEEEECCCCEEEEEEHHHHCCCCCCCEEECCCCEEEEEEECCCEEECCCHHHHHHHHCCC
SPFVHSNG
CCCEECCC
>Mature Secondary Structure 
TAFQALDLPEVILVTPRRFGDARGYFCETYVKPLYAANGIVADFVQDNESLSALPGTVR
CCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
GLHMQAPPFAQAKLVRVLSGAIFDVAVDVRKGSPTYGRWAGARLTAEGGEQLFVPQGFAH
EEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCC
GFCTLAPDTRVAYKVDAFYDRASECGIIWNDPDLAIDWRFTGETILSDKDRILPRLKDFD
CEEEECCCCEEEEEEHHHHCCCCCCCEEECCCCEEEEEEECCCEEECCCHHHHHHHHCCC
SPFVHSNG
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]