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The map label for this gene is oxyR [H]

Identifier: 154247410

GI number: 154247410

Start: 3877472

End: 3878401

Strand: Reverse

Name: oxyR [H]

Synonym: Xaut_3482

Alternate gene names: 154247410

Gene position: 3878401-3877472 (Counterclockwise)

Preceding gene: 154247412

Following gene: 154247409

Centisome position: 73.05

GC content: 68.17

Gene sequence:

>930_bases
ATGATCGATAAGCTTGAATACCTGATCGCCCTCGCCCGGGAACGTCACTTCGGCCGCGCCGGCGAAGCCTGCGGGGTGAC
GCAGCCCACCCTTTCCGCCGGAATCAAGCAGCTGGAAGACACGCTGGGGGTGCTGCTGGTGCAGCGCGGCTCGCGCTTCA
TGGGCTTTACGCCCGAGGGCGAGCGCACGCTGGAATGGGCGCGGCGCATCGTGGCCGATTCGCGGGCCATGCGGCAGGAC
ATCGACGCGCTCAAGCGCGGCCTTGCCGGCCCGCTGCGCATCGCCGCCATTCCCACCGCCCTGCCCATGGTGGCAGCATT
GACCACCCCCTTCCGCGCCCGCCACCCGGACGTTCGCTTCACGGTGATCTCCCGCACCTCCATCGAGATCCTGAACCATC
TCGAAAACCTGGAGATCGACGCCGGCCTCACCTATCTCGACAACGAGCCGCTGGGCCGGGTGAACACGGTGCCGCTCTAT
CGCGAGCGCTACCGGCTCGTCACCTCGCCCCAGTCCCGCTACGGCGAGCGCGACGCGGTGACCTGGGCGGAGGTGGCCGA
GCTCCAGCTCGCCCTGCTCACCCCCGACATGCAGAACCGCCGCATCGTGGACAATCTGCTTGCCGCCGCCGGCGCCAGCC
ACAAGCCGACGCTCGAATCCAATTCCATGATCGTGCTCTTCACCCACGTGCGCACCGGCCTGTGGGCGAGCGTGATGCCG
GCCATGCTGGCGGATTCGCTGGGGCTGACCTCGGTGGTGCGGTCGATTCCCATCGTGGAGCCGGACATCTCCCACTCCAT
CGGCCTGGTGGTGCCCCACCGCGAGCCGACCACGCCCATCACCGCCGCCCTGGTGGCGGAAGCCCGCCGCATCGCGCCGA
AGCTGGAGCAGAGCGGTATCGCCGATCCGGCCATTGCTGCAATGCAATAA

Upstream 100 bases:

>100_bases
AGCGCACCCATCCGGCGGCGGCCGTTCCCGGGCGGCGATCGCTGCGCTGCGGCAACACAGCCGCCTTGCGCGGCACCCCC
CGTCTCCGTGATATGGGGCC

Downstream 100 bases:

>100_bases
ATCCGACGGGGCCGACTGCGACAGCACGGCCCCGTGCATAGAAAAACACGATCAATATACCAAGAACCATCCCAGACAGA
CGCGATTGACGCAGCGCGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIDKLEYLIALARERHFGRAGEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEGERTLEWARRIVADSRAMRQD
IDALKRGLAGPLRIAAIPTALPMVAALTTPFRARHPDVRFTVISRTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLY
RERYRLVTSPQSRYGERDAVTWAEVAELQLALLTPDMQNRRIVDNLLAAAGASHKPTLESNSMIVLFTHVRTGLWASVMP
AMLADSLGLTSVVRSIPIVEPDISHSIGLVVPHREPTTPITAALVAEARRIAPKLEQSGIADPAIAAMQ

Sequences:

>Translated_309_residues
MIDKLEYLIALARERHFGRAGEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEGERTLEWARRIVADSRAMRQD
IDALKRGLAGPLRIAAIPTALPMVAALTTPFRARHPDVRFTVISRTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLY
RERYRLVTSPQSRYGERDAVTWAEVAELQLALLTPDMQNRRIVDNLLAAAGASHKPTLESNSMIVLFTHVRTGLWASVMP
AMLADSLGLTSVVRSIPIVEPDISHSIGLVVPHREPTTPITAALVAEARRIAPKLEQSGIADPAIAAMQ
>Mature_309_residues
MIDKLEYLIALARERHFGRAGEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEGERTLEWARRIVADSRAMRQD
IDALKRGLAGPLRIAAIPTALPMVAALTTPFRARHPDVRFTVISRTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLY
RERYRLVTSPQSRYGERDAVTWAEVAELQLALLTPDMQNRRIVDNLLAAAGASHKPTLESNSMIVLFTHVRTGLWASVMP
AMLADSLGLTSVVRSIPIVEPDISHSIGLVVPHREPTTPITAALVAEARRIAPKLEQSGIADPAIAAMQ

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=28.9285714285714, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI157672245, Length=259, Percent_Identity=27.4131274131274, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788748, Length=262, Percent_Identity=25.9541984732824, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=273, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786401, Length=182, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI2367136, Length=171, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=28.1786941580756, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788296, Length=215, Percent_Identity=28.8372093023256, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=146, Percent_Identity=30.1369863013699, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33884; Mature: 33884

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKLEYLIALARERHFGRAGEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
ERTLEWARRIVADSRAMRQDIDALKRGLAGPLRIAAIPTALPMVAALTTPFRARHPDVRF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCEEE
TVISRTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLYRERYRLVTSPQSRYGERDAV
EEECCHHHHHHHHHHCCEECCCCEEECCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCH
TWAEVAELQLALLTPDMQNRRIVDNLLAAAGASHKPTLESNSMIVLFTHVRTGLWASVMP
HHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHH
AMLADSLGLTSVVRSIPIVEPDISHSIGLVVPHREPTTPITAALVAEARRIAPKLEQSGI
HHHHHHCCHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ADPAIAAMQ
CCCHHHCCC
>Mature Secondary Structure
MIDKLEYLIALARERHFGRAGEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
ERTLEWARRIVADSRAMRQDIDALKRGLAGPLRIAAIPTALPMVAALTTPFRARHPDVRF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCEEE
TVISRTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLYRERYRLVTSPQSRYGERDAV
EEECCHHHHHHHHHHCCEECCCCEEECCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCH
TWAEVAELQLALLTPDMQNRRIVDNLLAAAGASHKPTLESNSMIVLFTHVRTGLWASVMP
HHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHH
AMLADSLGLTSVVRSIPIVEPDISHSIGLVVPHREPTTPITAALVAEARRIAPKLEQSGI
HHHHHHCCHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ADPAIAAMQ
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]