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The map label for this gene is ompR [H]

Identifier: 154247331

GI number: 154247331

Start: 3789518

End: 3790228

Strand: Direct

Name: ompR [H]

Synonym: Xaut_3403

Alternate gene names: 154247331

Gene position: 3789518-3790228 (Clockwise)

Preceding gene: 154247330

Following gene: 154247332

Centisome position: 71.38

GC content: 68.21

Gene sequence:

>711_bases
GTGTCCCCCGAAGGCCATATCCTGATCGTCGACGACGACGCGGAGATCCGGCGCCTCGCCGGCAAGTTCCTGCGCGAGCA
TGGGCACAAGGTCACCACGGCCCAGGACGCACGCGAGATGCGCGAGGCGATGAAGGCGGGGCCGGTGGATCTCATCATCC
TCGACATCATGCTGCCGGGCGCGAGCGGGCTCGACCTGTGCCGGGACATCCGCCGCACCTCCAGCGTGCCCATCATCATG
CTCACCGCGCGCGGCAGTGACGTGGACCGCATCGTGGGGCTGGAGCTGGGTGCGGATGACTATCTGTCGAAGCCGTTCAA
TCCGCGCGAGCTGCTGGCGCGCATCCATGCGGTGCTGCGGCGCATGCGGCCTTCCGGTGGCGCCGCGACCGGCGGCTCCC
TGCTCAACTTCGCCGGCTGGACGCTCGACACCCGCCGGCGCGAGCTCACCAATCCGGCGGCCGTCGTGGTGGACCTCTCC
ACCGGCGAATACGACCTGCTCCTGACCTTCCTCGAACACCCCCAAAGGGTACTGACCCGCGACCAGCTGATGGACGCCGC
CAAGAACCGCACCGCCACGGGCTTCGACCGCGCCATCGACATCCAGGTCAGCCGGCTGCGCAAGAAGCTTGAATCCCACG
GCGGGCCGGAGATGGTGAAGACCGTGCGCGGCGCCGGTTATTTCTTCGTCCCGGAGGTGGAACGCTCGTGA

Upstream 100 bases:

>100_bases
GCCAACTTCAGATGGCGAAGCCGGCCTGCTGGGATAAAAGGGCTTGTCCGCGAAGCCGCCGGCGCGCTTGCGGGCCGGCT
ACGCAGGAGTGCGTCACCCC

Downstream 100 bases:

>100_bases
TCCGCGCCCTCATCCGCGCATCGGACAGCCTCGCCGTGCGCACCGCCGTGGTGGCGGTGCTGGGCATCGTTGTCGTGCAT
CTGCTGAGCCTGTGGACCTA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSPEGHILIVDDDAEIRRLAGKFLREHGHKVTTAQDAREMREAMKAGPVDLIILDIMLPGASGLDLCRDIRRTSSVPIIM
LTARGSDVDRIVGLELGADDYLSKPFNPRELLARIHAVLRRMRPSGGAATGGSLLNFAGWTLDTRRRELTNPAAVVVDLS
TGEYDLLLTFLEHPQRVLTRDQLMDAAKNRTATGFDRAIDIQVSRLRKKLESHGGPEMVKTVRGAGYFFVPEVERS

Sequences:

>Translated_236_residues
MSPEGHILIVDDDAEIRRLAGKFLREHGHKVTTAQDAREMREAMKAGPVDLIILDIMLPGASGLDLCRDIRRTSSVPIIM
LTARGSDVDRIVGLELGADDYLSKPFNPRELLARIHAVLRRMRPSGGAATGGSLLNFAGWTLDTRRRELTNPAAVVVDLS
TGEYDLLLTFLEHPQRVLTRDQLMDAAKNRTATGFDRAIDIQVSRLRKKLESHGGPEMVKTVRGAGYFFVPEVERS
>Mature_235_residues
SPEGHILIVDDDAEIRRLAGKFLREHGHKVTTAQDAREMREAMKAGPVDLIILDIMLPGASGLDLCRDIRRTSSVPIIML
TARGSDVDRIVGLELGADDYLSKPFNPRELLARIHAVLRRMRPSGGAATGGSLLNFAGWTLDTRRRELTNPAAVVVDLST
GEYDLLLTFLEHPQRVLTRDQLMDAAKNRTATGFDRAIDIQVSRLRKKLESHGGPEMVKTVRGAGYFFVPEVERS

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=42.7966101694915, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=39.647577092511, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=36.480686695279, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=36.4864864864865, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=40.7894736842105, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=35.4978354978355, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=36.480686695279, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=38.1578947368421, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.4821428571429, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.4782608695652, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.5638766519824, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=31.2775330396476, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=37.1681415929204, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=29.2682926829268, Blast_Score=64, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=119, Percent_Identity=32.7731092436975, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26138; Mature: 26006

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEGHILIVDDDAEIRRLAGKFLREHGHKVTTAQDAREMREAMKAGPVDLIILDIMLPG
CCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCC
ASGLDLCRDIRRTSSVPIIMLTARGSDVDRIVGLELGADDYLSKPFNPRELLARIHAVLR
CCCHHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCHHHHCCCCCHHHHHHHHHHHHH
RMRPSGGAATGGSLLNFAGWTLDTRRRELTNPAAVVVDLSTGEYDLLLTFLEHPQRVLTR
HHCCCCCCCCCCHHHHHCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHCHHHHHHH
DQLMDAAKNRTATGFDRAIDIQVSRLRKKLESHGGPEMVKTVRGAGYFFVPEVERS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure 
SPEGHILIVDDDAEIRRLAGKFLREHGHKVTTAQDAREMREAMKAGPVDLIILDIMLPG
CCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCC
ASGLDLCRDIRRTSSVPIIMLTARGSDVDRIVGLELGADDYLSKPFNPRELLARIHAVLR
CCCHHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCHHHHCCCCCHHHHHHHHHHHHH
RMRPSGGAATGGSLLNFAGWTLDTRRRELTNPAAVVVDLSTGEYDLLLTFLEHPQRVLTR
HHCCCCCCCCCCHHHHHCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHCHHHHHHH
DQLMDAAKNRTATGFDRAIDIQVSRLRKKLESHGGPEMVKTVRGAGYFFVPEVERS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]