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The map label for this gene is CYP102A1 [H]

Identifier: 154247323

GI number: 154247323

Start: 3782243

End: 3784441

Strand: Reverse

Name: CYP102A1 [H]

Synonym: Xaut_3395

Alternate gene names: 154247323

Gene position: 3784441-3782243 (Counterclockwise)

Preceding gene: 154247324

Following gene: 154247322

Centisome position: 71.28

GC content: 72.99

Gene sequence:

>2199_bases
ATGCTTCGCCGCCTTCATGCGCTGCCGGGTCTGGTGCTTGCGCTCGGCCTCACCGTCACCGCCCTCTCCGGCGCCGCGCT
CTCCATCCAGCCGGCGCTCGACCGCCTCGCTGCGCCGGCAATCCCGTCCGGCACCAGCGTGGCGGCGCTCGCCGAGGCGG
TGTCCGTCCGCCACCAGAGCGTCGATGCCATCCGCCTCAGGGCGGACGGAAGCCTCACCGTCGCCTTTAACGATGGCGGC
GGGCGCGGCGTGGAGCAGGTCGATCCTGCCACCGGCGCGGGTCTCGGCCCCTACCGGGTTTCCGACACGACGAGGTTCGT
GACGAACCTGCATCGTGCCTTCCTTTCCGGCGATGCCGGACGCGCCGTGGCGGGGATCTGCGCCCTCGCCATGCTCATCC
TGTCGGTCTCGGGCGCCGTCCTGCTTGCCCGCCGCCTCGGCGGCGCGGGCGCATTGCTGCGCCCCATCCGGGGCACGCCG
GCGCAGCGCTGGCACGGCGAGCTCGGCCGCCTCGCCGCCGCCGGCCTCATTCTCTCCTCCCTCACGGGACTGTGGATGTC
GGCGGGCAGCTTCGGCCTCATCCCCGGGACCGAGGGCACGGTACCGGAAGTCGTGGCGAGCGCCGGCGGGCCAGCGCCGG
TCGGAACGCTGGCGGCGCTGCGGTCCGTCGATGTGACGCGTATGCGCGAACTGACATTCCCCGCCCCCGGCGATCCGAGC
GACACCTACGGCCTGCGGACGGCGGCGGGCGAAGCGCGGATCGATGCGGCGACGGGCGCGGAGCTGTCCTTCACCCCCGC
GACGCCGCTCGACCGCCTGAACGACCTGGTGCGCACCCTCCATACCGGCCGGGGCGCCTGGGCGCTCGGGCTTCTGCTCG
GCCTTTCGGCGGCCACGGTCCCGGTGCTCGGTGCGACCGGCGCCGTGATGTGGTGGCGCCGCCGCGCCGCCCGGCCGCGC
ATTGCGATGAACGCCCCCCTGCGCACCGCCGACACTCTCATCCTGGTGGGCAGCGACGGCAATTCCACCTGGGGATTTGC
CGCGACGCTCCACGCCGCGCTGACCCGGGCCGGCCATCGCGTCCACACCACGGCCATGAATGAATTCCGAGCGCTCCCCG
AGGCCACGCAACGCCTGCTGGTCCTGGCCGCGACCCACGGGGACGGCGCAGCTCCCGGCTCGGCGAGTTCATTCCTGCCG
CGCCTCGCGCACCTCGCGCCCCGGCTGGACCGCCGGGTACCGGTGGCGGTGCTCGGCTTCGGCGACCGCACCTTCCCCCG
CTTCTGCGGCTATGCCGAGCAGGTGTCGGCCGCGTTCGCGGCGCAGGGCTTTCCGCAACTCCAGCCCCTGAAGCGCATCG
ACCGTCGCTCGGCGCAGGAATTCGCGCAGTGGGGCCGCGACCTCGGATCCAGCCTCGGCCACGATCTGGTGCTCGAACAT
ACGGCGGAGCGGCCGAAGACCCTCGCGCTCGAACTGGCGTCGCGCGAGGACTACGGCGCGGCCATTGGCGCACCGGTGGC
GATCCTGCGGTTTCGCGGGCCCGGACGGGGCGCGGCTGCGGGACGCCTGCCGGCCTTCGAGCCTGGCGACCTTCTCGGCA
TTCTGGCGCCGGGCGCCGACATGCCGCGGTTCTACTCTCTCGCATCGTCGTCGCGGGACGGGATGGTGGAAATCTGCGTC
CGCCTGCGCGCGGGCGGGCTCTGCTCCACCTTCCTGCATGGCCTCGCGCCGGGCGACAGGGTGGAAGCCTTCGTCCGCGC
CAATCCCGTCTTCCGGCCGGCCAAGGGCCGGGCGCCGCTCATCCTGATTGGCGCCGGCGCCGGCATCGGCCCGCTCGCCG
GGCTGGTGCGGGCCAACGCGGCGGGTCGGCCGGTCCACCTCTACTGGGGTGGCCGGAGCCCCTCGTCCGACTTCCTCTAC
GAGCACGAACTGGCCCAGCACCTCGCAGAGAAGCGCCTGACCTCGCTCCAGACGGCCTTTTCGCGAGGCCCGGATGGCCG
CGCCTATGTGCAGGACCGCATCGCCGCCGATGCCCCCCGCCTGCGCGAGCTGGTGAGGCAGGGCGCGCAGATCCTGGTGT
GCGGCGGCCGCGACATGGCCGAGGCGGTGACGCGTGCCTTCGAGCCGGTGGTGCGACCGCTGGGCCTCGATCTTGCGACC
CTCAAATCTCACGGACGCTACGTCGAAGATGTCTATTGA

Upstream 100 bases:

>100_bases
AGTGGTGGTGCCGCTCGACACCGCAGCCTCGGGCAAGCCGGTGCCCGGCAAGGGCTACGTCAAATCCTTCTCGGTCACCT
TCTGAACCTGACAGGTCCTC

Downstream 100 bases:

>100_bases
GCCGGTCTCCCGACCCTCGGCGCTGAGCCGCCACGCGCTGAGCGGCCCCGCCATGGGGTCGCGCTGGTCCGCTGTCTTCT
GGTCGAACGCAAAGGTCGAT

Product: oxidoreductase FAD/NAD(P)-binding subunit

Products: NA

Alternate protein names: Cytochrome P450(BM-3); Cytochrome P450BM-3; Cytochrome P450 102; NADPH--cytochrome P450 reductase [H]

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MLRRLHALPGLVLALGLTVTALSGAALSIQPALDRLAAPAIPSGTSVAALAEAVSVRHQSVDAIRLRADGSLTVAFNDGG
GRGVEQVDPATGAGLGPYRVSDTTRFVTNLHRAFLSGDAGRAVAGICALAMLILSVSGAVLLARRLGGAGALLRPIRGTP
AQRWHGELGRLAAAGLILSSLTGLWMSAGSFGLIPGTEGTVPEVVASAGGPAPVGTLAALRSVDVTRMRELTFPAPGDPS
DTYGLRTAAGEARIDAATGAELSFTPATPLDRLNDLVRTLHTGRGAWALGLLLGLSAATVPVLGATGAVMWWRRRAARPR
IAMNAPLRTADTLILVGSDGNSTWGFAATLHAALTRAGHRVHTTAMNEFRALPEATQRLLVLAATHGDGAAPGSASSFLP
RLAHLAPRLDRRVPVAVLGFGDRTFPRFCGYAEQVSAAFAAQGFPQLQPLKRIDRRSAQEFAQWGRDLGSSLGHDLVLEH
TAERPKTLALELASREDYGAAIGAPVAILRFRGPGRGAAAGRLPAFEPGDLLGILAPGADMPRFYSLASSSRDGMVEICV
RLRAGGLCSTFLHGLAPGDRVEAFVRANPVFRPAKGRAPLILIGAGAGIGPLAGLVRANAAGRPVHLYWGGRSPSSDFLY
EHELAQHLAEKRLTSLQTAFSRGPDGRAYVQDRIAADAPRLRELVRQGAQILVCGGRDMAEAVTRAFEPVVRPLGLDLAT
LKSHGRYVEDVY

Sequences:

>Translated_732_residues
MLRRLHALPGLVLALGLTVTALSGAALSIQPALDRLAAPAIPSGTSVAALAEAVSVRHQSVDAIRLRADGSLTVAFNDGG
GRGVEQVDPATGAGLGPYRVSDTTRFVTNLHRAFLSGDAGRAVAGICALAMLILSVSGAVLLARRLGGAGALLRPIRGTP
AQRWHGELGRLAAAGLILSSLTGLWMSAGSFGLIPGTEGTVPEVVASAGGPAPVGTLAALRSVDVTRMRELTFPAPGDPS
DTYGLRTAAGEARIDAATGAELSFTPATPLDRLNDLVRTLHTGRGAWALGLLLGLSAATVPVLGATGAVMWWRRRAARPR
IAMNAPLRTADTLILVGSDGNSTWGFAATLHAALTRAGHRVHTTAMNEFRALPEATQRLLVLAATHGDGAAPGSASSFLP
RLAHLAPRLDRRVPVAVLGFGDRTFPRFCGYAEQVSAAFAAQGFPQLQPLKRIDRRSAQEFAQWGRDLGSSLGHDLVLEH
TAERPKTLALELASREDYGAAIGAPVAILRFRGPGRGAAAGRLPAFEPGDLLGILAPGADMPRFYSLASSSRDGMVEICV
RLRAGGLCSTFLHGLAPGDRVEAFVRANPVFRPAKGRAPLILIGAGAGIGPLAGLVRANAAGRPVHLYWGGRSPSSDFLY
EHELAQHLAEKRLTSLQTAFSRGPDGRAYVQDRIAADAPRLRELVRQGAQILVCGGRDMAEAVTRAFEPVVRPLGLDLAT
LKSHGRYVEDVY
>Mature_732_residues
MLRRLHALPGLVLALGLTVTALSGAALSIQPALDRLAAPAIPSGTSVAALAEAVSVRHQSVDAIRLRADGSLTVAFNDGG
GRGVEQVDPATGAGLGPYRVSDTTRFVTNLHRAFLSGDAGRAVAGICALAMLILSVSGAVLLARRLGGAGALLRPIRGTP
AQRWHGELGRLAAAGLILSSLTGLWMSAGSFGLIPGTEGTVPEVVASAGGPAPVGTLAALRSVDVTRMRELTFPAPGDPS
DTYGLRTAAGEARIDAATGAELSFTPATPLDRLNDLVRTLHTGRGAWALGLLLGLSAATVPVLGATGAVMWWRRRAARPR
IAMNAPLRTADTLILVGSDGNSTWGFAATLHAALTRAGHRVHTTAMNEFRALPEATQRLLVLAATHGDGAAPGSASSFLP
RLAHLAPRLDRRVPVAVLGFGDRTFPRFCGYAEQVSAAFAAQGFPQLQPLKRIDRRSAQEFAQWGRDLGSSLGHDLVLEH
TAERPKTLALELASREDYGAAIGAPVAILRFRGPGRGAAAGRLPAFEPGDLLGILAPGADMPRFYSLASSSRDGMVEICV
RLRAGGLCSTFLHGLAPGDRVEAFVRANPVFRPAKGRAPLILIGAGAGIGPLAGLVRANAAGRPVHLYWGGRSPSSDFLY
EHELAQHLAEKRLTSLQTAFSRGPDGRAYVQDRIAADAPRLRELVRQGAQILVCGGRDMAEAVTRAFEPVVRPLGLDLAT
LKSHGRYVEDVY

Specific function: Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is re

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=238, Percent_Identity=34.0336134453782, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI24041029, Length=224, Percent_Identity=32.1428571428571, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI40254422, Length=225, Percent_Identity=32, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI10835173, Length=224, Percent_Identity=29.0178571428571, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI221316709, Length=274, Percent_Identity=27.3722627737226, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1789123, Length=226, Percent_Identity=31.858407079646, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554134, Length=191, Percent_Identity=31.413612565445, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17566446, Length=178, Percent_Identity=33.1460674157303, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321832, Length=172, Percent_Identity=33.1395348837209, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325305, Length=170, Percent_Identity=26.4705882352941, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583543, Length=235, Percent_Identity=31.063829787234, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI78706876, Length=235, Percent_Identity=31.063829787234, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI78706872, Length=235, Percent_Identity=31.063829787234, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24660907, Length=176, Percent_Identity=26.7045454545455, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24660903, Length=176, Percent_Identity=26.7045454545455, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17137192, Length=225, Percent_Identity=25.3333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582192, Length=226, Percent_Identity=24.7787610619469, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023206
- InterPro:   IPR001128
- InterPro:   IPR015702
- InterPro:   IPR017972
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1; PF00067 p450 [H]

EC number: =1.14.14.1; =1.6.2.4 [H]

Molecular weight: Translated: 76523; Mature: 76523

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRLHALPGLVLALGLTVTALSGAALSIQPALDRLAAPAIPSGTSVAALAEAVSVRHQS
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
VDAIRLRADGSLTVAFNDGGGRGVEQVDPATGAGLGPYRVSDTTRFVTNLHRAFLSGDAG
CCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCC
RAVAGICALAMLILSVSGAVLLARRLGGAGALLRPIRGTPAQRWHGELGRLAAAGLILSS
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LTGLWMSAGSFGLIPGTEGTVPEVVASAGGPAPVGTLAALRSVDVTRMRELTFPAPGDPS
HHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC
DTYGLRTAAGEARIDAATGAELSFTPATPLDRLNDLVRTLHTGRGAWALGLLLGLSAATV
CCCCCEECCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
PVLGATGAVMWWRRRAARPRIAMNAPLRTADTLILVGSDGNSTWGFAATLHAALTRAGHR
HHHCCCHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VHTTAMNEFRALPEATQRLLVLAATHGDGAAPGSASSFLPRLAHLAPRLDRRVPVAVLGF
EEHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC
GDRTFPRFCGYAEQVSAAFAAQGFPQLQPLKRIDRRSAQEFAQWGRDLGSSLGHDLVLEH
CCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TAERPKTLALELASREDYGAAIGAPVAILRFRGPGRGAAAGRLPAFEPGDLLGILAPGAD
HCCCCCEEEEEECCCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCC
MPRFYSLASSSRDGMVEICVRLRAGGLCSTFLHGLAPGDRVEAFVRANPVFRPAKGRAPL
CCHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCE
ILIGAGAGIGPLAGLVRANAAGRPVHLYWGGRSPSSDFLYEHELAQHLAEKRLTSLQTAF
EEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRGPDGRAYVQDRIAADAPRLRELVRQGAQILVCGGRDMAEAVTRAFEPVVRPLGLDLAT
HCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHH
LKSHGRYVEDVY
HHHCCCCHHCCC
>Mature Secondary Structure
MLRRLHALPGLVLALGLTVTALSGAALSIQPALDRLAAPAIPSGTSVAALAEAVSVRHQS
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
VDAIRLRADGSLTVAFNDGGGRGVEQVDPATGAGLGPYRVSDTTRFVTNLHRAFLSGDAG
CCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCC
RAVAGICALAMLILSVSGAVLLARRLGGAGALLRPIRGTPAQRWHGELGRLAAAGLILSS
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LTGLWMSAGSFGLIPGTEGTVPEVVASAGGPAPVGTLAALRSVDVTRMRELTFPAPGDPS
HHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC
DTYGLRTAAGEARIDAATGAELSFTPATPLDRLNDLVRTLHTGRGAWALGLLLGLSAATV
CCCCCEECCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
PVLGATGAVMWWRRRAARPRIAMNAPLRTADTLILVGSDGNSTWGFAATLHAALTRAGHR
HHHCCCHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VHTTAMNEFRALPEATQRLLVLAATHGDGAAPGSASSFLPRLAHLAPRLDRRVPVAVLGF
EEHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC
GDRTFPRFCGYAEQVSAAFAAQGFPQLQPLKRIDRRSAQEFAQWGRDLGSSLGHDLVLEH
CCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TAERPKTLALELASREDYGAAIGAPVAILRFRGPGRGAAAGRLPAFEPGDLLGILAPGAD
HCCCCCEEEEEECCCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCC
MPRFYSLASSSRDGMVEICVRLRAGGLCSTFLHGLAPGDRVEAFVRANPVFRPAKGRAPL
CCHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCE
ILIGAGAGIGPLAGLVRANAAGRPVHLYWGGRSPSSDFLYEHELAQHLAEKRLTSLQTAF
EEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SRGPDGRAYVQDRIAADAPRLRELVRQGAQILVCGGRDMAEAVTRAFEPVVRPLGLDLAT
HCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHH
LKSHGRYVEDVY
HHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544578; 1727637; 8342039; 9033595; 10051560; 11695892 [H]