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The map label for this gene is aldH [H]

Identifier: 154247302

GI number: 154247302

Start: 3760531

End: 3762057

Strand: Direct

Name: aldH [H]

Synonym: Xaut_3374

Alternate gene names: 154247302

Gene position: 3760531-3762057 (Clockwise)

Preceding gene: 154247301

Following gene: 154247310

Centisome position: 70.83

GC content: 71.84

Gene sequence:

>1527_bases
ATGGACGCGACCCCTGACGGCGGCCACCTGATCGCCGGGGCCTGGGTAGCCGGCGGCCCCACCTTCGAGAGCGCGCCGGC
CACCGGCACGCCGCGCCGCTTCTTCTCGGCGACCGAAGTTGAGGTGGATGCGGCCGCACGCGCGGCGGAAGACGCCTTCG
CCTCGTTTGGCTGGTCCAGCCGCAAGGCGCGGGCGGAGTTCCTCGACGCCATCGCCGCGCAGATGGAGGCGCGCGGCGCC
GACATCACCGCCATCGCGCAGGAGGAGACCGGCCTGCCGGCGCCCCGCCTCGCCGGGGAACTGGCGCGCACCACCGGGCA
ATTGCGCCTGTTCGCCCGCCACATCCTTGCCGGCGCCTATCTGGACCGGCGCCACGACGTGGCCTTGCCGGACCGCCAGC
CCCTGCCACGGCCGGACATTCGGCTGATGCAACGGCCCATCGGGCCGGTGGCGGTGTTCGGCGCCTCCAACTTCCCGCTC
GCCTTCTCTGTGGCTGGCGGCGACACCGCCTCTGCCCTCGCCGCCGGCTGCCCGGTGGTGGTGAAGGGCCATCCCGCCCA
TCCCGGCACCAGCCAGAAGGTGGCCGAGGCCATCGACGCAGCGCGCGCGGCGCTGGACCTTCATCCCGGCGTGTTCGCTC
TGCTCCAGTCCTTCACGGTGGAGGGCGGCACCGCGCTGGTGCGCCATCCGCTCATCAAGGCGGTGGGGTTCACCGGCAGT
CTCGGCGCGGGGCGTGCCCTGTTCGACCTGTGCGCCGCCCGCCCGGAACCGATCCCCTTCTTCGGCGAGCTGGGCTCGGT
CAATCCCATGTTCCTGCTGCCGGCGGCGTTGAAGGCGCGTAGCGGTACGCTCGGCGCCGGCTGGGCCGGGTCGCTCTCCA
TGGGCGTCGGCCAGTTTTGCACCAATCCCGGCATCGCCTTCGCCGTCGACGGGCCGGACACGGATGCCTTCCTTGCCGCG
ACTGAGGCGGGACTGGGACAGGTGGCGCCGCAGCCCATGCTGACCGATGGCATCGCCGCCGCCTTCCGCCGCGGGCGGGA
CCATGTGGCGCAAACGCCTGCCGTGCGATGCGCGTTGAAGGCAGACGCCGACGGCCGCAACGGCGCGCCGGCCCTGTTCG
AGACCACGGGCGCCGCCTTCCGCGCCGATTCAAGCCTTGCTCACGAGGTGTTCGGGCCGCTCGGCATCCTGGTGCGGGTC
GAGGATGAGGATGAGATGGTCGCGCTCGCGGCGGGGCTGGAAGGCCAACTCACAGCCACCCTCCAGATGGATGCGGACGA
CACGCCACTGGCCAAGCGGCTGATGCCGATCCTCGAGCGCAAGGCAGGCCGGGTGCTGGCCAATGGCTTTCCCACCGGCG
TCGAGGTCTGCGATGCCATGGTGCATGGCGGGCCTTATCCCGCCTCCACCAATTTCGGCGCCACCTCGGTGGGGACGATG
GCCATCCGCCGCTTCCTGCGACCGGTGAGCTACCAGAACCTGCCCGACGCGCTGTTGCCGGCGGACCTGCTGGAAGGCGG
GGCCTGA

Upstream 100 bases:

>100_bases
GAGTTGGAGGCCAGCCTGCCACGGCCGGCACCCGATGCGCCCATGGCGCTCTATCAGGGTGGCCAGTTCACCCAGGATCC
GATTTTCGAGGAGAAGTGAG

Downstream 100 bases:

>100_bases
GCGGCCCCGTCTCGAAGGTTCAGAGCACCACGGTGAACGGGGTGATGTCGGCGAAGTCCTCGTCGTCCGGGCCGAAGTCG
CGCCACATGAAGATGGCGAA

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MDATPDGGHLIAGAWVAGGPTFESAPATGTPRRFFSATEVEVDAAARAAEDAFASFGWSSRKARAEFLDAIAAQMEARGA
DITAIAQEETGLPAPRLAGELARTTGQLRLFARHILAGAYLDRRHDVALPDRQPLPRPDIRLMQRPIGPVAVFGASNFPL
AFSVAGGDTASALAAGCPVVVKGHPAHPGTSQKVAEAIDAARAALDLHPGVFALLQSFTVEGGTALVRHPLIKAVGFTGS
LGAGRALFDLCAARPEPIPFFGELGSVNPMFLLPAALKARSGTLGAGWAGSLSMGVGQFCTNPGIAFAVDGPDTDAFLAA
TEAGLGQVAPQPMLTDGIAAAFRRGRDHVAQTPAVRCALKADADGRNGAPALFETTGAAFRADSSLAHEVFGPLGILVRV
EDEDEMVALAAGLEGQLTATLQMDADDTPLAKRLMPILERKAGRVLANGFPTGVEVCDAMVHGGPYPASTNFGATSVGTM
AIRRFLRPVSYQNLPDALLPADLLEGGA

Sequences:

>Translated_508_residues
MDATPDGGHLIAGAWVAGGPTFESAPATGTPRRFFSATEVEVDAAARAAEDAFASFGWSSRKARAEFLDAIAAQMEARGA
DITAIAQEETGLPAPRLAGELARTTGQLRLFARHILAGAYLDRRHDVALPDRQPLPRPDIRLMQRPIGPVAVFGASNFPL
AFSVAGGDTASALAAGCPVVVKGHPAHPGTSQKVAEAIDAARAALDLHPGVFALLQSFTVEGGTALVRHPLIKAVGFTGS
LGAGRALFDLCAARPEPIPFFGELGSVNPMFLLPAALKARSGTLGAGWAGSLSMGVGQFCTNPGIAFAVDGPDTDAFLAA
TEAGLGQVAPQPMLTDGIAAAFRRGRDHVAQTPAVRCALKADADGRNGAPALFETTGAAFRADSSLAHEVFGPLGILVRV
EDEDEMVALAAGLEGQLTATLQMDADDTPLAKRLMPILERKAGRVLANGFPTGVEVCDAMVHGGPYPASTNFGATSVGTM
AIRRFLRPVSYQNLPDALLPADLLEGGA
>Mature_508_residues
MDATPDGGHLIAGAWVAGGPTFESAPATGTPRRFFSATEVEVDAAARAAEDAFASFGWSSRKARAEFLDAIAAQMEARGA
DITAIAQEETGLPAPRLAGELARTTGQLRLFARHILAGAYLDRRHDVALPDRQPLPRPDIRLMQRPIGPVAVFGASNFPL
AFSVAGGDTASALAAGCPVVVKGHPAHPGTSQKVAEAIDAARAALDLHPGVFALLQSFTVEGGTALVRHPLIKAVGFTGS
LGAGRALFDLCAARPEPIPFFGELGSVNPMFLLPAALKARSGTLGAGWAGSLSMGVGQFCTNPGIAFAVDGPDTDAFLAA
TEAGLGQVAPQPMLTDGIAAAFRRGRDHVAQTPAVRCALKADADGRNGAPALFETTGAAFRADSSLAHEVFGPLGILVRV
EDEDEMVALAAGLEGQLTATLQMDADDTPLAKRLMPILERKAGRVLANGFPTGVEVCDAMVHGGPYPASTNFGATSVGTM
AIRRFLRPVSYQNLPDALLPADLLEGGA

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87081896, Length=409, Percent_Identity=27.6283618581907, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788042, Length=425, Percent_Identity=27.2941176470588, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789015, Length=432, Percent_Identity=26.1574074074074, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787558, Length=477, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71995606, Length=390, Percent_Identity=27.4358974358974, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71995613, Length=390, Percent_Identity=27.4358974358974, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362580, Length=432, Percent_Identity=26.6203703703704, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI62472918, Length=432, Percent_Identity=26.6203703703704, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI62472926, Length=432, Percent_Identity=26.6203703703704, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI62472936, Length=432, Percent_Identity=26.6203703703704, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356737, Length=432, Percent_Identity=26.6203703703704, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 52432; Mature: 52432

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATPDGGHLIAGAWVAGGPTFESAPATGTPRRFFSATEVEVDAAARAAEDAFASFGWSS
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHCCCCC
RKARAEFLDAIAAQMEARGADITAIAQEETGLPAPRLAGELARTTGQLRLFARHILAGAY
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRRHDVALPDRQPLPRPDIRLMQRPIGPVAVFGASNFPLAFSVAGGDTASALAAGCPVV
HCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCCCEE
VKGHPAHPGTSQKVAEAIDAARAALDLHPGVFALLQSFTVEGGTALVRHPLIKAVGFTGS
EECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
LGAGRALFDLCAARPEPIPFFGELGSVNPMFLLPAALKARSGTLGAGWAGSLSMGVGQFC
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCHHHCHHHHH
TNPGIAFAVDGPDTDAFLAATEAGLGQVAPQPMLTDGIAAAFRRGRDHVAQTPAVRCALK
CCCCEEEEECCCCCCCEEEEHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCCHHEEEEE
ADADGRNGAPALFETTGAAFRADSSLAHEVFGPLGILVRVEDEDEMVALAAGLEGQLTAT
CCCCCCCCCCCCEECCCCHHCCCCHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCEEEE
LQMDADDTPLAKRLMPILERKAGRVLANGFPTGVEVCDAMVHGGPYPASTNFGATSVGTM
EEECCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AIRRFLRPVSYQNLPDALLPADLLEGGA
HHHHHHHHCCCCCCCCHHCCHHHHCCCC
>Mature Secondary Structure
MDATPDGGHLIAGAWVAGGPTFESAPATGTPRRFFSATEVEVDAAARAAEDAFASFGWSS
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHCCCCC
RKARAEFLDAIAAQMEARGADITAIAQEETGLPAPRLAGELARTTGQLRLFARHILAGAY
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRRHDVALPDRQPLPRPDIRLMQRPIGPVAVFGASNFPLAFSVAGGDTASALAAGCPVV
HCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCCCEE
VKGHPAHPGTSQKVAEAIDAARAALDLHPGVFALLQSFTVEGGTALVRHPLIKAVGFTGS
EECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
LGAGRALFDLCAARPEPIPFFGELGSVNPMFLLPAALKARSGTLGAGWAGSLSMGVGQFC
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCHHHCHHHHH
TNPGIAFAVDGPDTDAFLAATEAGLGQVAPQPMLTDGIAAAFRRGRDHVAQTPAVRCALK
CCCCEEEEECCCCCCCEEEEHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCCHHEEEEE
ADADGRNGAPALFETTGAAFRADSSLAHEVFGPLGILVRVEDEDEMVALAAGLEGQLTAT
CCCCCCCCCCCCEECCCCHHCCCCHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCEEEE
LQMDADDTPLAKRLMPILERKAGRVLANGFPTGVEVCDAMVHGGPYPASTNFGATSVGTM
EEECCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AIRRFLRPVSYQNLPDALLPADLLEGGA
HHHHHHHHCCCCCCCCHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]