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The map label for this gene is yccK [H]

Identifier: 154247264

GI number: 154247264

Start: 3710379

End: 3711374

Strand: Reverse

Name: yccK [H]

Synonym: Xaut_3336

Alternate gene names: 154247264

Gene position: 3711374-3710379 (Counterclockwise)

Preceding gene: 154247266

Following gene: 154247263

Centisome position: 69.91

GC content: 66.06

Gene sequence:

>996_bases
ATGAAAACACGCATGCTGGGCAAGAACGGACTTGAGGTTTCAGCCTTGGGCTTCGGCTGCATGGGCCTCAACTTCAGCTA
TGGCCACGCACTGGACAGCAATGATGCCATCGCCCTCATCCGGCAGACGGTGGAACGGGGCGTGACGTTTTTCGACACCG
CCGAAATCTACGGCCCCTTCACCAATGAAGAGATCGTCGGCGCGGCGCTGGCGCCGGTGCGCGAGCGGGTGGTGATCGCC
ACCAAGTTCGGATTCGCCATCGATCCCAAGACCGGCAAGCAGACCGGAATGGACAGCCGCCCCGAGCACATCCGCGCGGT
CTGCGATGCCTCCCTCAAGCGGCTGGGGGTGGAGGTCATCGACCTGTTCTACCAGCACCGCGTGGACCCCAACGTCCCCA
TCGAGGACGTGGCCGGCGCCGTGAAGGACCTGATCGCGGAAGGCAAGGTGAAGCATTTCGGTCTCTCCGAACCCGGTGCG
CAGACGGTGCGCCGCGCCCATGCGGTGCAGCCTGTCACGGCGCTGCAGAACGAATATTCCCTGTGGACGCGCGGGCCGGA
GACGAATGGCATCCTTGAGGCGAGCGAGGAGCTGGGCATCGGCCTCGTGGCGTACAGCCCCCTCGGCAAGGGCTTCCTCA
CCGGAGCCATGGGCCGGGACACCAAGCTCGCCGACGGGGACTTCCGCAGCATCCTGCCGCGCTTCACGCCGCAGGCCATG
GAAAAGAACCAGGCGCTGGTGGACCTGCTGAAACGCATCGCCGCCGGCAAACAGGCCACGCCCGCCCAGGTCGCACTGGC
CTGGCTTCTGGCGCAAAAACCCTGGATCGTGCCCATCCCCGGCACCACCAAGCTCAACCGGCTGGAGGAGAACCTGGGCG
CGGCCGACATCACGCTGTCCGCCGCCGACCTCGCCGAGATCGAACAGGCGGCGGCCGGGATCCAGGTGGAAGGCGAACGC
TATCCCGAGCAGCTCATGGCCACCATCGGCCGCTGA

Upstream 100 bases:

>100_bases
TAATCCATGGATCGACCACGCCCTATTTTCACGGACGCACCGGGCACCCGTTCCCGAGCCCCCCGGACGAGCCAAATGGA
CGAGCCCACTGGAGACGACC

Downstream 100 bases:

>100_bases
GCGGCCCGACCCGTCGGACGCATTGCGCGCGGGTCCCAACAAAAACCGGAGAACACCAGCATGTCCGACAACATCGCAGG
CAAGGTCGTCGTCATCACCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKTRMLGKNGLEVSALGFGCMGLNFSYGHALDSNDAIALIRQTVERGVTFFDTAEIYGPFTNEEIVGAALAPVRERVVIA
TKFGFAIDPKTGKQTGMDSRPEHIRAVCDASLKRLGVEVIDLFYQHRVDPNVPIEDVAGAVKDLIAEGKVKHFGLSEPGA
QTVRRAHAVQPVTALQNEYSLWTRGPETNGILEASEELGIGLVAYSPLGKGFLTGAMGRDTKLADGDFRSILPRFTPQAM
EKNQALVDLLKRIAAGKQATPAQVALAWLLAQKPWIVPIPGTTKLNRLEENLGAADITLSAADLAEIEQAAAGIQVEGER
YPEQLMATIGR

Sequences:

>Translated_331_residues
MKTRMLGKNGLEVSALGFGCMGLNFSYGHALDSNDAIALIRQTVERGVTFFDTAEIYGPFTNEEIVGAALAPVRERVVIA
TKFGFAIDPKTGKQTGMDSRPEHIRAVCDASLKRLGVEVIDLFYQHRVDPNVPIEDVAGAVKDLIAEGKVKHFGLSEPGA
QTVRRAHAVQPVTALQNEYSLWTRGPETNGILEASEELGIGLVAYSPLGKGFLTGAMGRDTKLADGDFRSILPRFTPQAM
EKNQALVDLLKRIAAGKQATPAQVALAWLLAQKPWIVPIPGTTKLNRLEENLGAADITLSAADLAEIEQAAAGIQVEGER
YPEQLMATIGR
>Mature_331_residues
MKTRMLGKNGLEVSALGFGCMGLNFSYGHALDSNDAIALIRQTVERGVTFFDTAEIYGPFTNEEIVGAALAPVRERVVIA
TKFGFAIDPKTGKQTGMDSRPEHIRAVCDASLKRLGVEVIDLFYQHRVDPNVPIEDVAGAVKDLIAEGKVKHFGLSEPGA
QTVRRAHAVQPVTALQNEYSLWTRGPETNGILEASEELGIGLVAYSPLGKGFLTGAMGRDTKLADGDFRSILPRFTPQAM
EKNQALVDLLKRIAAGKQATPAQVALAWLLAQKPWIVPIPGTTKLNRLEENLGAADITLSAADLAEIEQAAAGIQVEGER
YPEQLMATIGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=29.0322580645161, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=28.7096774193548, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI27436966, Length=310, Percent_Identity=28.7096774193548, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI27436969, Length=323, Percent_Identity=26.9349845201238, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4504825, Length=320, Percent_Identity=26.875, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=29.6774193548387, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI223718702, Length=297, Percent_Identity=30.6397306397306, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41152114, Length=294, Percent_Identity=28.2312925170068, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI41327764, Length=293, Percent_Identity=29.6928327645051, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI223718708, Length=139, Percent_Identity=34.5323741007194, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=32.7272727272727, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=32.8125, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=30.7926829268293, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=29.8076923076923, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=30.9248554913295, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788081, Length=278, Percent_Identity=26.6187050359712, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994888, Length=301, Percent_Identity=28.9036544850498, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325384, Length=347, Percent_Identity=28.2420749279539, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325169, Length=339, Percent_Identity=26.5486725663717, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=328, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=23.9864864864865, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=299, Percent_Identity=25.0836120401338, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=24.7011952191235, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640980, Length=341, Percent_Identity=25.2199413489736, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI45549126, Length=341, Percent_Identity=25.2199413489736, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646155, Length=162, Percent_Identity=32.7160493827161, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646159, Length=226, Percent_Identity=24.7787610619469, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 35674; Mature: 35674

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRMLGKNGLEVSALGFGCMGLNFSYGHALDSNDAIALIRQTVERGVTFFDTAEIYGPF
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHHCCCC
TNEEIVGAALAPVRERVVIATKFGFAIDPKTGKQTGMDSRPEHIRAVCDASLKRLGVEVI
CCCHHHHHHHHHHHHEEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPNVPIEDVAGAVKDLIAEGKVKHFGLSEPGAQTVRRAHAVQPVTALQNEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCC
LWTRGPETNGILEASEELGIGLVAYSPLGKGFLTGAMGRDTKLADGDFRSILPRFTPQAM
EEECCCCCCCCEECHHHCCEEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCHHHH
EKNQALVDLLKRIAAGKQATPAQVALAWLLAQKPWIVPIPGTTKLNRLEENLGAADITLS
HCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEC
AADLAEIEQAAAGIQVEGERYPEQLMATIGR
HHHHHHHHHHHCCCEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MKTRMLGKNGLEVSALGFGCMGLNFSYGHALDSNDAIALIRQTVERGVTFFDTAEIYGPF
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHHCCCC
TNEEIVGAALAPVRERVVIATKFGFAIDPKTGKQTGMDSRPEHIRAVCDASLKRLGVEVI
CCCHHHHHHHHHHHHEEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPNVPIEDVAGAVKDLIAEGKVKHFGLSEPGAQTVRRAHAVQPVTALQNEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCC
LWTRGPETNGILEASEELGIGLVAYSPLGKGFLTGAMGRDTKLADGDFRSILPRFTPQAM
EEECCCCCCCCEECHHHCCEEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCHHHH
EKNQALVDLLKRIAAGKQATPAQVALAWLLAQKPWIVPIPGTTKLNRLEENLGAADITLS
HCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEC
AADLAEIEQAAAGIQVEGERYPEQLMATIGR
HHHHHHHHHHHCCCEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]