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The map label for this gene is cobT [H]

Identifier: 154247249

GI number: 154247249

Start: 3694517

End: 3695611

Strand: Direct

Name: cobT [H]

Synonym: Xaut_3321

Alternate gene names: 154247249

Gene position: 3694517-3695611 (Clockwise)

Preceding gene: 154247248

Following gene: 154247251

Centisome position: 69.59

GC content: 70.78

Gene sequence:

>1095_bases
TTGGCTCTATGCAGCGGCTTTCCGTTCCCGCGCCGGGTCCTGCGTCCCGGTGCCGCTTCAGGTAGCCTGCCCATGTATCC
GAGCGAATCCGGCCTGCCCTTCGACGACATCCGCCAGCTCGTCGCCACCATGCCCGGCCCGTCCGAGGGCGCGCGGGAGG
CGGCTCTGGCGCGGCAGGAACAGCTGGTGAAGCCCCTCGGCGCGCTGGGCCGGCTGGAGGCCATCGCCGCCCATCTCGCG
GCCTGGCAGGGCAATTCCATGCCCACCGTAAACCGGCCCATGGTGGCGGTATTCGCCGCGACCCATGGCATCGCCGATCG
CGGCGTCTCGCCCTATCCCGGCGCGGTGACCAAGCAGATGATGGCCACCTTCACCGCCGGCAAGGCGGCCGTGAACCAGA
TCTGCGCCACCTTCGACGCCGGGCTGCGGGTGTTCGACCTCGCCCTCGACTATCCCACCCCGGACATCACCCAGGGCGCT
GCGCTTGATGAGAAGGCCTGCGCGGCCACCATGGCCTTCGGCATGGAGGCCATCGCCGGCGGGTCGGATCTTTTGTGCCT
CGGCGAGATGGGTATCGGCAACACCACCATCGCAGCCGCCTTGTGCCACGGGCTTTACGGCGGCACGGCGGAGGAGTGGG
TAGGCGCCGGCACCGGCTCCACGGGCGAGGTGCTGGAGCGCAAGATCGCCGCGGTGCGCGATGCCGTGGCGTTCCACAAG
GACCACCTGTCCGATCCGCTGGAGGTGCTGCGCCGCCTTGGCGGGCGCGAAATCGCCGCCATCGCAGGCGCCATCATCGC
CGCGCGGCACGAGAAGGTGCCGGTGGTGCTGGATGGTTTCGTGGTCACCGCCGCCGCCGCCGTGCTCCACGCCCTCGACC
CGTCCGCTCTCGACCATTGCCTCGCCGGCCATGTCTCGGCGGAGAAGGCCCATCGCGCGCTGCTCGACCGGCTGGGCCTG
CGTCCGATCCTCGACCTCGACATGCGGCTGGGGGAAGGCTCAGGCGCGGCGCTGGCCATCGGCGTGGTGAAGGCGGCGGT
GGCCTGCCATCGTGGCATGGCCACCTTCGCCGAGGCCGGGGTGTCCGAAGGCTGA

Upstream 100 bases:

>100_bases
CCCTGGTCCCGCTGCCTGACCGAAGCCGCGCCTTCCGGGGCGTGAGTCGCGTACTCGACCCTACCGGTTCGCCCTTCTGC
CCCCTTCGCTCGGAGGCACT

Downstream 100 bases:

>100_bases
AAGCTCAGGAGTGCAGGGCGCGCGCGGGAGGAAACGTCACTTCGGCCCGCGTGCCGCCGCCAGGCCGCCGCTCCAGCGCC
AATGCGCCGCCGTGCAGGCC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MALCSGFPFPRRVLRPGAASGSLPMYPSESGLPFDDIRQLVATMPGPSEGAREAALARQEQLVKPLGALGRLEAIAAHLA
AWQGNSMPTVNRPMVAVFAATHGIADRGVSPYPGAVTKQMMATFTAGKAAVNQICATFDAGLRVFDLALDYPTPDITQGA
ALDEKACAATMAFGMEAIAGGSDLLCLGEMGIGNTTIAAALCHGLYGGTAEEWVGAGTGSTGEVLERKIAAVRDAVAFHK
DHLSDPLEVLRRLGGREIAAIAGAIIAARHEKVPVVLDGFVVTAAAAVLHALDPSALDHCLAGHVSAEKAHRALLDRLGL
RPILDLDMRLGEGSGAALAIGVVKAAVACHRGMATFAEAGVSEG

Sequences:

>Translated_364_residues
MALCSGFPFPRRVLRPGAASGSLPMYPSESGLPFDDIRQLVATMPGPSEGAREAALARQEQLVKPLGALGRLEAIAAHLA
AWQGNSMPTVNRPMVAVFAATHGIADRGVSPYPGAVTKQMMATFTAGKAAVNQICATFDAGLRVFDLALDYPTPDITQGA
ALDEKACAATMAFGMEAIAGGSDLLCLGEMGIGNTTIAAALCHGLYGGTAEEWVGAGTGSTGEVLERKIAAVRDAVAFHK
DHLSDPLEVLRRLGGREIAAIAGAIIAARHEKVPVVLDGFVVTAAAAVLHALDPSALDHCLAGHVSAEKAHRALLDRLGL
RPILDLDMRLGEGSGAALAIGVVKAAVACHRGMATFAEAGVSEG
>Mature_363_residues
ALCSGFPFPRRVLRPGAASGSLPMYPSESGLPFDDIRQLVATMPGPSEGAREAALARQEQLVKPLGALGRLEAIAAHLAA
WQGNSMPTVNRPMVAVFAATHGIADRGVSPYPGAVTKQMMATFTAGKAAVNQICATFDAGLRVFDLALDYPTPDITQGAA
LDEKACAATMAFGMEAIAGGSDLLCLGEMGIGNTTIAAALCHGLYGGTAEEWVGAGTGSTGEVLERKIAAVRDAVAFHKD
HLSDPLEVLRRLGGREIAAIAGAIIAARHEKVPVVLDGFVVTAAAAVLHALDPSALDHCLAGHVSAEKAHRALLDRLGLR
PILDLDMRLGEGSGAALAIGVVKAAVACHRGMATFAEAGVSEG

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=341, Percent_Identity=33.4310850439883, Blast_Score=168, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37397; Mature: 37265

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALCSGFPFPRRVLRPGAASGSLPMYPSESGLPFDDIRQLVATMPGPSEGAREAALARQE
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
QLVKPLGALGRLEAIAAHLAAWQGNSMPTVNRPMVAVFAATHGIADRGVSPYPGAVTKQM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHHCHHHCCCCCCCCHHHHHH
MATFTAGKAAVNQICATFDAGLRVFDLALDYPTPDITQGAALDEKACAATMAFGMEAIAG
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
GSDLLCLGEMGIGNTTIAAALCHGLYGGTAEEWVGAGTGSTGEVLERKIAAVRDAVAFHK
CCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
DHLSDPLEVLRRLGGREIAAIAGAIIAARHEKVPVVLDGFVVTAAAAVLHALDPSALDHC
HHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHH
LAGHVSAEKAHRALLDRLGLRPILDLDMRLGEGSGAALAIGVVKAAVACHRGMATFAEAG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
VSEG
CCCC
>Mature Secondary Structure 
ALCSGFPFPRRVLRPGAASGSLPMYPSESGLPFDDIRQLVATMPGPSEGAREAALARQE
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
QLVKPLGALGRLEAIAAHLAAWQGNSMPTVNRPMVAVFAATHGIADRGVSPYPGAVTKQM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEHHHHHCHHHCCCCCCCCHHHHHH
MATFTAGKAAVNQICATFDAGLRVFDLALDYPTPDITQGAALDEKACAATMAFGMEAIAG
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
GSDLLCLGEMGIGNTTIAAALCHGLYGGTAEEWVGAGTGSTGEVLERKIAAVRDAVAFHK
CCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
DHLSDPLEVLRRLGGREIAAIAGAIIAARHEKVPVVLDGFVVTAAAAVLHALDPSALDHC
HHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHH
LAGHVSAEKAHRALLDRLGLRPILDLDMRLGEGSGAALAIGVVKAAVACHRGMATFAEAG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
VSEG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA