BacMap

Definition	Xanthobacter autotrophicus Py2 chromosome, complete genome.
Accession	NC_009720
Length	5,308,934

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The map label for this gene is fadB1 [H]

Identifier: 154247236

GI number: 154247236

Start: 3677448

End: 3678218

Strand: Direct

Name: fadB1 [H]

Synonym: Xaut_3308

Alternate gene names: 154247236

Gene position: 3677448-3678218 (Clockwise)

Preceding gene: 154247235

Following gene: 154247238

Centisome position: 69.27

GC content: 66.54

Gene sequence:

>771_bases
ATGGCATACGAGACGATCCTGGTGGAGCAGCACGACCGCGTGGGGCTCATCCGCCTGAACCGCCCCCAGGCGCTCAATGC
GCTCAACGGCCAGCTGATCGGCGAGCTGAACGCGGCGCTGGATGCGTTCGAGCAGGATCGGGGCATCGGCTGCGTTGTTC
TCACCGGCTCGGAGAAGGCGTTCGCCGCCGGGGCCGACATCAAGGAGATGCAAGTCTTCTCCTATCCGGCGACCTATCTC
GACGATTTCATCACCTCCTGGGAGCGGCTGTCGCGCACCCGCAAGCCGGTGATCGCGGCGGTGGCGGGCTTCGCCCTGGG
TGGCGGCTGCGAGCTGGCCATGATGTGCGACTTCATCCTGGCCGCCGATACCGCGAAGTTCGGCCAGCCCGAGATCAAGC
TGGGGGTGATGCCCGGTGCCGGCGGCACTCAGCGCCTCACCCGATTCGTGGGCAAGTCGAAGGCCATGGAAATGTGCCTC
ACCGGCCGCTTGATGGATGCCGTCGAAGCCGAGCGCGCTGGCCTCGTCTCGCGCGTGGTGCCGGCAGCCGAGCTTCTGGA
CGAGGCGCTGAAGGTGGCGAAGGTCATCGCCGGCATGTCCGCGCACGTGGCCATGCAGACCAAGGAAAGCGTGAACCGCT
CCTACGAGACCACGCTTGCCGAAGGCATCCGCTTCGAGCGGCGGGTGTTCCAGGCCCAGTTCGGCGTCGCCGACCAGAAG
GAAGGCATGGCCGCCTTCATCGAGAAGCGCCCCGCGAAGTTCGAGCACTGA

Upstream 100 bases:

>100_bases
CGGTGACCGCGCGTGCTGGCGCCGCGCGGAGCCTTAAGCCGGCGTCTCGCCGGGGGACGAGCATGACCCGGCGTCACGCC
GGGCGACGAGGAGGAATGGG

Downstream 100 bases:

>100_bases
GGGCCGTTCGCGCACAGGGCGATTCGTCTGGGTGATGCGGGCATCGAGGCCCGGCTCGGCGGAGGGACGGACCATCGCGA
TGGCGGAGCGTTTCCGCCAT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MAYETILVEQHDRVGLIRLNRPQALNALNGQLIGELNAALDAFEQDRGIGCVVLTGSEKAFAAGADIKEMQVFSYPATYL
DDFITSWERLSRTRKPVIAAVAGFALGGGCELAMMCDFILAADTAKFGQPEIKLGVMPGAGGTQRLTRFVGKSKAMEMCL
TGRLMDAVEAERAGLVSRVVPAAELLDEALKVAKVIAGMSAHVAMQTKESVNRSYETTLAEGIRFERRVFQAQFGVADQK
EGMAAFIEKRPAKFEH

Sequences:

>Translated_256_residues
MAYETILVEQHDRVGLIRLNRPQALNALNGQLIGELNAALDAFEQDRGIGCVVLTGSEKAFAAGADIKEMQVFSYPATYL
DDFITSWERLSRTRKPVIAAVAGFALGGGCELAMMCDFILAADTAKFGQPEIKLGVMPGAGGTQRLTRFVGKSKAMEMCL
TGRLMDAVEAERAGLVSRVVPAAELLDEALKVAKVIAGMSAHVAMQTKESVNRSYETTLAEGIRFERRVFQAQFGVADQK
EGMAAFIEKRPAKFEH
>Mature_255_residues
AYETILVEQHDRVGLIRLNRPQALNALNGQLIGELNAALDAFEQDRGIGCVVLTGSEKAFAAGADIKEMQVFSYPATYLD
DFITSWERLSRTRKPVIAAVAGFALGGGCELAMMCDFILAADTAKFGQPEIKLGVMPGAGGTQRLTRFVGKSKAMEMCLT
GRLMDAVEAERAGLVSRVVPAAELLDEALKVAKVIAGMSAHVAMQTKESVNRSYETTLAEGIRFERRVFQAQFGVADQKE
GMAAFIEKRPAKFEH

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=256, Percent_Identity=55.078125, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI68989263, Length=187, Percent_Identity=36.3636363636364, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=34.1085271317829, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=28, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI70995211, Length=240, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI20127408, Length=177, Percent_Identity=36.1581920903955, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI150378541, Length=243, Percent_Identity=32.5102880658436, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI37594469, Length=199, Percent_Identity=31.1557788944724, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI37594471, Length=199, Percent_Identity=31.1557788944724, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI213417737, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI157694516, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI260274832, Length=257, Percent_Identity=26.0700389105058, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI45643119, Length=257, Percent_Identity=26.0700389105058, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI260275230, Length=257, Percent_Identity=26.0700389105058, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4757968, Length=264, Percent_Identity=25.3787878787879, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI49355787, Length=264, Percent_Identity=25.3787878787879, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI25453481, Length=263, Percent_Identity=25.4752851711027, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI51538573, Length=263, Percent_Identity=25.4752851711027, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221136756, Length=262, Percent_Identity=25.5725190839695, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221136753, Length=262, Percent_Identity=25.5725190839695, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI62530384, Length=211, Percent_Identity=26.0663507109005, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI221307494, Length=262, Percent_Identity=25.1908396946565, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI157694520, Length=217, Percent_Identity=27.1889400921659, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4757966, Length=252, Percent_Identity=25.7936507936508, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI51538581, Length=252, Percent_Identity=25.7936507936508, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI261878539, Length=93, Percent_Identity=38.7096774193548, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787659, Length=250, Percent_Identity=44.8, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=35.1778656126482, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1788597, Length=202, Percent_Identity=38.6138613861386, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=33.976833976834, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790281, Length=188, Percent_Identity=34.5744680851064, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082183, Length=260, Percent_Identity=31.5384615384615, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788682, Length=193, Percent_Identity=35.2331606217617, Blast_Score=101, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=52.9182879377432, Blast_Score=274, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=51.0288065843621, Blast_Score=251, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17540714, Length=220, Percent_Identity=31.8181818181818, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17540306, Length=237, Percent_Identity=34.5991561181435, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560910, Length=247, Percent_Identity=32.3886639676113, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17558304, Length=188, Percent_Identity=32.9787234042553, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144276, Length=192, Percent_Identity=34.375, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17508953, Length=192, Percent_Identity=34.375, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17508951, Length=192, Percent_Identity=34.375, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17536985, Length=265, Percent_Identity=26.4150943396226, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=257, Percent_Identity=28.4046692607004, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25144160, Length=195, Percent_Identity=31.2820512820513, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI25144157, Length=195, Percent_Identity=31.2820512820513, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=212, Percent_Identity=29.7169811320755, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=254, Percent_Identity=24.0157480314961, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320241, Length=196, Percent_Identity=27.5510204081633, Blast_Score=89, Evalue=6e-19,
Organism=Drosophila melanogaster, GI20129971, Length=257, Percent_Identity=59.9221789883268, Blast_Score=309, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24653477, Length=257, Percent_Identity=59.9221789883268, Blast_Score=309, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24653139, Length=259, Percent_Identity=35.9073359073359, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19922422, Length=257, Percent_Identity=30.7392996108949, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24650670, Length=212, Percent_Identity=35.377358490566, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357171, Length=249, Percent_Identity=30.9236947791165, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19920382, Length=223, Percent_Identity=34.5291479820628, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24654903, Length=194, Percent_Identity=29.8969072164948, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24583077, Length=178, Percent_Identity=33.1460674157303, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583079, Length=178, Percent_Identity=33.1460674157303, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921000, Length=178, Percent_Identity=33.1460674157303, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571729, Length=187, Percent_Identity=26.7379679144385, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571730, Length=187, Percent_Identity=26.7379679144385, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921018, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583165, Length=175, Percent_Identity=27.4285714285714, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27779; Mature: 27648

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYETILVEQHDRVGLIRLNRPQALNALNGQLIGELNAALDAFEQDRGIGCVVLTGSEKA
CCCCEEEEECCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FAAGADIKEMQVFSYPATYLDDFITSWERLSRTRKPVIAAVAGFALGGGCELAMMCDFIL
EECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AADTAKFGQPEIKLGVMPGAGGTQRLTRFVGKSKAMEMCLTGRLMDAVEAERAGLVSRVV
HHCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAAELLDEALKVAKVIAGMSAHVAMQTKESVNRSYETTLAEGIRFERRVFQAQFGVADQK
HHHHHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGMAAFIEKRPAKFEH
CHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AYETILVEQHDRVGLIRLNRPQALNALNGQLIGELNAALDAFEQDRGIGCVVLTGSEKA
CCCEEEEECCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FAAGADIKEMQVFSYPATYLDDFITSWERLSRTRKPVIAAVAGFALGGGCELAMMCDFIL
EECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AADTAKFGQPEIKLGVMPGAGGTQRLTRFVGKSKAMEMCLTGRLMDAVEAERAGLVSRVV
HHCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAAELLDEALKVAKVIAGMSAHVAMQTKESVNRSYETTLAEGIRFERRVFQAQFGVADQK
HHHHHHHHHHHHHHHHHCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGMAAFIEKRPAKFEH
CHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]