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The map label for this gene is fmt [H]

Identifier: 154247232

GI number: 154247232

Start: 3673439

End: 3674362

Strand: Reverse

Name: fmt [H]

Synonym: Xaut_3304

Alternate gene names: 154247232

Gene position: 3674362-3673439 (Counterclockwise)

Preceding gene: 154247233

Following gene: 154247231

Centisome position: 69.21

GC content: 71.54

Gene sequence:

>924_bases
ATGCGCATCGTCTTCATGGGAACGCCGGATTTCGCCGTGCCGACCCTTTCCGAGATTGTCGGACGTGGGCACGAGGTGGT
GGCCGTCTATACCCGCGCGCCGGCTCCGGCCGGGCGGCGCGGGCTCGATCTCACCCCCTCCCCGGTGCATCAGGTGGCCG
AGCGCTTCGGCCTCAAGGTTCTCACTCCGAAAAGCCTGCGCACCCCGGAAGCGGCGGCCGAATTTGCCGCCCATGACGCC
GACGTGGCGGTGGTGGTGGCCTATGGCCTCATCCTGCCGCTGGCGATCCTTGAGGCGCCGCGCCTCGGCTGCCTCAACCT
GCACGGTTCGCTTCTGCCCCGCTGGCGCGGCGCCGCGCCCATCCAGCGCGCCATCATGGCCGGGGATCAGGCGACGGGCG
TCTGTGTGATGCAGATGGAGCAGGGCCTCGACACCGGCCCCGTCGGTCTCGTGGAGCGCATCCCCATCGGCCCGGACATG
ACGGCGGGCGACCTGCATGATCGCATGATGGTGCTGGGCGCCGACCTGATGGCCCGCGCACTGGCGGCGCTGGAGCGCGG
CGGCCTCGCCTTCACCGCCCAGCCGGAGGCGGGCGTCGCCTATGCCGCCAAGATCGAGAAGGCGGAAACCCGCATCGACT
GGTCGCAGCCGGCGCAGGTGGTGCACGATCGCATCCGCGGCCTCTCCCCCTTCCCCGGTGCCTGGTTTCCGCTGGGGCCG
GACGAGACGCGGGTGAAGGTGCTGCGCTCGACCCTCGCGGAGGGCGCGGGTCCCCCCGGCGACGTGCTGGACGACCGCCT
CACCATCGCCTGCGGCTCCGGCGCGGTGCGGCTGGTGGAATTGCAGAAGGCCGGCAAGCAGCCGGCGGGTGCGTCGAGCT
TTCTCAACGGGAATGCCGTGCCGCCCGGCACCCGGCTCACCTGA

Upstream 100 bases:

>100_bases
CGCCTTTCCCGCTTTCCCGCTGATGCCGTCGCATCCGGGTCCTTTCGCTCAATCGCCGCGCACCTGACTGGACGGGTCGC
GCCGGCCCGGATCAGGCAGC

Downstream 100 bases:

>100_bases
GCCGCCGGCTCGCCCCGCCATGCCGCGCTACAAGCTGACCATCGAATATGATGGCACCCCCTATGCCGGCTGGCAGATCC
AGGCCGACCAGCAGACCGTG

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRIVFMGTPDFAVPTLSEIVGRGHEVVAVYTRAPAPAGRRGLDLTPSPVHQVAERFGLKVLTPKSLRTPEAAAEFAAHDA
DVAVVVAYGLILPLAILEAPRLGCLNLHGSLLPRWRGAAPIQRAIMAGDQATGVCVMQMEQGLDTGPVGLVERIPIGPDM
TAGDLHDRMMVLGADLMARALAALERGGLAFTAQPEAGVAYAAKIEKAETRIDWSQPAQVVHDRIRGLSPFPGAWFPLGP
DETRVKVLRSTLAEGAGPPGDVLDDRLTIACGSGAVRLVELQKAGKQPAGASSFLNGNAVPPGTRLT

Sequences:

>Translated_307_residues
MRIVFMGTPDFAVPTLSEIVGRGHEVVAVYTRAPAPAGRRGLDLTPSPVHQVAERFGLKVLTPKSLRTPEAAAEFAAHDA
DVAVVVAYGLILPLAILEAPRLGCLNLHGSLLPRWRGAAPIQRAIMAGDQATGVCVMQMEQGLDTGPVGLVERIPIGPDM
TAGDLHDRMMVLGADLMARALAALERGGLAFTAQPEAGVAYAAKIEKAETRIDWSQPAQVVHDRIRGLSPFPGAWFPLGP
DETRVKVLRSTLAEGAGPPGDVLDDRLTIACGSGAVRLVELQKAGKQPAGASSFLNGNAVPPGTRLT
>Mature_307_residues
MRIVFMGTPDFAVPTLSEIVGRGHEVVAVYTRAPAPAGRRGLDLTPSPVHQVAERFGLKVLTPKSLRTPEAAAEFAAHDA
DVAVVVAYGLILPLAILEAPRLGCLNLHGSLLPRWRGAAPIQRAIMAGDQATGVCVMQMEQGLDTGPVGLVERIPIGPDM
TAGDLHDRMMVLGADLMARALAALERGGLAFTAQPEAGVAYAAKIEKAETRIDWSQPAQVVHDRIRGLSPFPGAWFPLGP
DETRVKVLRSTLAEGAGPPGDVLDDRLTIACGSGAVRLVELQKAGKQPAGASSFLNGNAVPPGTRLT

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=270, Percent_Identity=31.8518518518519, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI238814322, Length=270, Percent_Identity=29.6296296296296, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI164663775, Length=325, Percent_Identity=28.9230769230769, Blast_Score=95, Evalue=8e-20,
Organism=Escherichia coli, GI1789683, Length=313, Percent_Identity=45.3674121405751, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1788589, Length=309, Percent_Identity=27.5080906148867, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI133930964, Length=272, Percent_Identity=29.4117647058824, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319458, Length=261, Percent_Identity=26.8199233716475, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550868, Length=306, Percent_Identity=30.3921568627451, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28571984, Length=227, Percent_Identity=33.0396475770925, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24585660, Length=237, Percent_Identity=27.0042194092827, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 32241; Mature: 32241

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVFMGTPDFAVPTLSEIVGRGHEVVAVYTRAPAPAGRRGLDLTPSPVHQVAERFGLKV
CEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEE
LTPKSLRTPEAAAEFAAHDADVAVVVAYGLILPLAILEAPRLGCLNLHGSLLPRWRGAAP
ECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHH
IQRAIMAGDQATGVCVMQMEQGLDTGPVGLVERIPIGPDMTAGDLHDRMMVLGADLMARA
HHHHHHCCCCCCCEEEEEHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LAALERGGLAFTAQPEAGVAYAAKIEKAETRIDWSQPAQVVHDRIRGLSPFPGAWFPLGP
HHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
DETRVKVLRSTLAEGAGPPGDVLDDRLTIACGSGAVRLVELQKAGKQPAGASSFLNGNAV
CHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCCEEEEEEHHCCCCCCCCHHCCCCCCC
PPGTRLT
CCCCCCC
>Mature Secondary Structure
MRIVFMGTPDFAVPTLSEIVGRGHEVVAVYTRAPAPAGRRGLDLTPSPVHQVAERFGLKV
CEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEE
LTPKSLRTPEAAAEFAAHDADVAVVVAYGLILPLAILEAPRLGCLNLHGSLLPRWRGAAP
ECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHH
IQRAIMAGDQATGVCVMQMEQGLDTGPVGLVERIPIGPDMTAGDLHDRMMVLGADLMARA
HHHHHHCCCCCCCEEEEEHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LAALERGGLAFTAQPEAGVAYAAKIEKAETRIDWSQPAQVVHDRIRGLSPFPGAWFPLGP
HHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
DETRVKVLRSTLAEGAGPPGDVLDDRLTIACGSGAVRLVELQKAGKQPAGASSFLNGNAV
CHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCCEEEEEEHHCCCCCCCCHHCCCCCCC
PPGTRLT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA