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The map label for this gene is ywlC [H]

Identifier: 154247193

GI number: 154247193

Start: 3626508

End: 3627545

Strand: Reverse

Name: ywlC [H]

Synonym: Xaut_3265

Alternate gene names: 154247193

Gene position: 3627545-3626508 (Counterclockwise)

Preceding gene: 154247195

Following gene: 154247192

Centisome position: 68.33

GC content: 74.28

Gene sequence:

>1038_bases
ATGGTTTCTCCCGCTCCGCCCCAGATGCGCCCGACCCGCCTTTTGCCGGCCGCCGCCCCCGGCGCTGTCGAAGAGGCGGC
GCGGCTTCTTTCCGGGGGCGGGCTCGTGGCCTTTCCCACCGAGACGGTCTACGGCCTCGGTGCCGATGCGGCGAACCCTC
AGGCCGTGGCCGCCCTCTATGCCGCCAAGGGGCGCCCGGCCTTCAACCCGCTGATCGCCCATACGAAGGACGCCGCCTCT
GCCCGCCGGCTCGGCAGCTTCAACCGGGCGGCGAACATTCTCGCGGAGCGCTTCTGGCCGGGGCCGCTGACGCTGGTGGT
GCCCTATGCCGGGGGCGACGGCGTCTGCGAACTGGCGCGGGCGGGGCTCGACACGGTGGCCCTGCGGGTGCCCGCCCATG
GCGATGCCGCCGCGCTCATCGCGGCCTTCGGCGGCGCGGTGGTGGCCCCCAGCGCCAACCGCTCGGGCCATGTCTCACCC
ACCACCGCCGCCCATGTGATGGACGACCTTTCCGGCCGTATCGATGCGGTTGTGGACGGCGGGCCAACGCCGGTGGGGGT
CGAATCCACCATTCTCGATGTCACCGGGGAGGTTCCGGTGCTGCTGCGTCCCGGAGGCCTGGCGCGGGAGGAGATCGAGG
CTGCCCTCGGCCACCCCATCGCGCGGCCTGTCGCCACCGATGACGCCCGCCCGCTGGCTCCGGGCCGCCTCGCCTCCCAT
TACGCGCCCCGCGCCGCGCTACGCCTCGACGCGACCCATGTCGCCCCGGGCGAAGCCCTGCTCACCTTCGCGGGGATGGC
ACCGGACGGCACGCCGAATGCCGGCAGCGTGCTCGACCTTAGCCCGTCCGGCGACCTCACCGAGGCCGCGGCCCGGCTCT
ATGGCGCGCTGCGGGCCCTCGATGCCTCGGGTGCATCCGCCATCGCCGTGGTGCCGCTGCCCCGCACCGGCCTTGGCGAA
GCCATCTCCGACCGCCTCGCGCGCGCTGCCGCGCCGCGCCCCTCCCCAGCCCCTTCCGGAAGCGAGATCCCCGCATGA

Upstream 100 bases:

>100_bases
CTAAGCACGCGACGTTCGGCTTCCCACATCGCGGCGCCGGCAGGCTTCGTCAAGGGGCGCGCCGTGGCCATTGGTCGGAC
ACGCGTGGATTGAAGGCATC

Downstream 100 bases:

>100_bases
CCGAGACGCTCGCCACCACCGCCGTTGAGGGTTTCGCCTTCAGCCATGCGCAGGACACCGACACGCCGGCGCTTGCCGCC
CTGTGGGAGCGCGCCGGCCT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MVSPAPPQMRPTRLLPAAAPGAVEEAARLLSGGGLVAFPTETVYGLGADAANPQAVAALYAAKGRPAFNPLIAHTKDAAS
ARRLGSFNRAANILAERFWPGPLTLVVPYAGGDGVCELARAGLDTVALRVPAHGDAAALIAAFGGAVVAPSANRSGHVSP
TTAAHVMDDLSGRIDAVVDGGPTPVGVESTILDVTGEVPVLLRPGGLAREEIEAALGHPIARPVATDDARPLAPGRLASH
YAPRAALRLDATHVAPGEALLTFAGMAPDGTPNAGSVLDLSPSGDLTEAAARLYGALRALDASGASAIAVVPLPRTGLGE
AISDRLARAAAPRPSPAPSGSEIPA

Sequences:

>Translated_345_residues
MVSPAPPQMRPTRLLPAAAPGAVEEAARLLSGGGLVAFPTETVYGLGADAANPQAVAALYAAKGRPAFNPLIAHTKDAAS
ARRLGSFNRAANILAERFWPGPLTLVVPYAGGDGVCELARAGLDTVALRVPAHGDAAALIAAFGGAVVAPSANRSGHVSP
TTAAHVMDDLSGRIDAVVDGGPTPVGVESTILDVTGEVPVLLRPGGLAREEIEAALGHPIARPVATDDARPLAPGRLASH
YAPRAALRLDATHVAPGEALLTFAGMAPDGTPNAGSVLDLSPSGDLTEAAARLYGALRALDASGASAIAVVPLPRTGLGE
AISDRLARAAAPRPSPAPSGSEIPA
>Mature_345_residues
MVSPAPPQMRPTRLLPAAAPGAVEEAARLLSGGGLVAFPTETVYGLGADAANPQAVAALYAAKGRPAFNPLIAHTKDAAS
ARRLGSFNRAANILAERFWPGPLTLVVPYAGGDGVCELARAGLDTVALRVPAHGDAAALIAAFGGAVVAPSANRSGHVSP
TTAAHVMDDLSGRIDAVVDGGPTPVGVESTILDVTGEVPVLLRPGGLAREEIEAALGHPIARPVATDDARPLAPGRLASH
YAPRAALRLDATHVAPGEALLTFAGMAPDGTPNAGSVLDLSPSGDLTEAAARLYGALRALDASGASAIAVVPLPRTGLGE
AISDRLARAAAPRPSPAPSGSEIPA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321269, Length=373, Percent_Identity=33.2439678284182, Blast_Score=146, Evalue=5e-36,
Organism=Drosophila melanogaster, GI78707274, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34480; Mature: 34480

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPAPPQMRPTRLLPAAAPGAVEEAARLLSGGGLVAFPTETVYGLGADAANPQAVAALY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCCHHHHHHHH
AAKGRPAFNPLIAHTKDAASARRLGSFNRAANILAERFWPGPLTLVVPYAGGDGVCELAR
HHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
AGLDTVALRVPAHGDAAALIAAFGGAVVAPSANRSGHVSPTTAAHVMDDLSGRIDAVVDG
CCCCEEEEEECCCCCHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECC
GPTPVGVESTILDVTGEVPVLLRPGGLAREEIEAALGHPIARPVATDDARPLAPGRLASH
CCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
YAPRAALRLDATHVAPGEALLTFAGMAPDGTPNAGSVLDLSPSGDLTEAAARLYGALRAL
CCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
DASGASAIAVVPLPRTGLGEAISDRLARAAAPRPSPAPSGSEIPA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVSPAPPQMRPTRLLPAAAPGAVEEAARLLSGGGLVAFPTETVYGLGADAANPQAVAALY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCCCHHHHHHHH
AAKGRPAFNPLIAHTKDAASARRLGSFNRAANILAERFWPGPLTLVVPYAGGDGVCELAR
HHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
AGLDTVALRVPAHGDAAALIAAFGGAVVAPSANRSGHVSPTTAAHVMDDLSGRIDAVVDG
CCCCEEEEEECCCCCHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECC
GPTPVGVESTILDVTGEVPVLLRPGGLAREEIEAALGHPIARPVATDDARPLAPGRLASH
CCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
YAPRAALRLDATHVAPGEALLTFAGMAPDGTPNAGSVLDLSPSGDLTEAAARLYGALRAL
CCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
DASGASAIAVVPLPRTGLGEAISDRLARAAAPRPSPAPSGSEIPA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]